Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

14-3-3 zeta/delta
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
6-phosphofructokinase, liver type
6-phosphofructokinase, muscle type
A-kinase anchoring protein.
Acetyl-CoA carboxylase 1
Acetylcholine receptor protein, delta chain
ADR1
Alpha adducin
APC
Aquaporin 0
Aquaporin 2
Arachidonate 5 lipoxygenase
ATP-binding cassette 1
ATP-citrate synthase
Aurora kinase A
Aurora-C
B-Raf
BAD
Beta adducin
Beta casein precursor
Beta-2 adrenergic receptor
Beta-ARK-1
Brain sodium channel 2
C/EBP beta
CAD
Calcium/calmodulin-dependent protein kinase kinase 1
cAMP-dependent protein kinase regulatory subunit
cAMP-dependent protein kinase type II-alpha regulatory subunit
cAMP-dependent protein kinase type II-beta regulatory subunit
cAMP-dependent protein kinase, alpha-catalytic subunit
CAPN2
Casein kinase I, delta isoform
CD243
CD42C
CD91
Centrin 1
CETN2
CFTR
Chorionic gonadotrophin beta subunit
Common beta c subunit
Connexin 32
CPI-17
CTP synthase
Cullin 5
Cut like 1
Cyclic-AMP-dependent transcription factor ATF-2
Cyclin D1
Cytochrome P450 2B1
Cytochrome P450 2B2
DARPP-32
Dematin
Desmin
Desmoplakin
DPDE4
Drp1
E3 ubiquitin-protein ligase Nedd-4-like protein
eIF-2-beta
Erythrocyte band 7 integral membrane protein
Erythrocyte membrane protein band 4.2
Estrogen receptor alpha
ETV5
FGF2
Fibrinogen alpha chain
Fructose-1,6-bisphosphatase
G alpha 13
GABA(A) receptor B1
GFAP
GFPT2
Glucosamine--fructose-6-phosphate aminotransferase
GluR-1
GluR-4
GluR-6
Glycogenin-1
GMF-beta
GRK7
GSK-3 alpha
GSK-3 beta
HAND1
HDAC8
Histone H1.1
Histone H2A.c/d/i/n/p
Histone H2B.a/g/h/k/l
HLA-A1
HMG14
hnRPA1
hnRPD
HRH1
HSP27
Inositol 1,4,5-trisphosphate receptor type 1
Integrin alpha 4
IPP1
L-plastin
Lamin Dm0
LASP1
Lipase hormone sensitive
Lipocortin I (annexinI)
Lysozyme C
MBP
Melanocortin 4 receptor
Merlin
MHC class II transactivator
MLCK
Moesin
Mybpc3
MYOM1
Neurabin II protein
Neutrophil cytosol factor 1
NF-ATc1
NFE2L1
NIPP1
Nitric-oxide synthase, brain
Nitric-oxide synthase, endothelial
Nopp140
NPR-A
Nuclear factor NF-kappa-B p105 subunit
Octamer binding transcription factor 1
Orphan nuclear receptor NR4A1
PCTAIRE1
Perilipin
Phenylalanine-4-hydroxylase
Phosducin
Phosphodiesterase 3B
Phosphodiesterase 5A
Phospholamban
Phospholemman precursor
Phosphorylase b kinase alpha regulatory chain, skeletal muscle isoform
Phosphorylase b kinase beta regulatory chain
Phytochrome A type 3
PIN1
PLC beta 3
PLC gamma 1
PMCA1
Potassium voltage-gated channel subfamily H member 2
PPP1R14D
Presenilin 1
Prostaglandin E2 receptor, EP4 subtype
Protamine YI
Protamine YII
Protamine Z
Protein phosphatase 1, regulatory subunit 3A
PTBP1
PTH/PTHr receptor
Pyruvate kinase, isozymes R/L
Raf1
Rap1GAP
Ras related protein 1A
Ras-related protein Rap-1b
Regulator of G-protein signaling 10, isoform a
REL
RGS14
Rho guanine nucleotide exchange factor 7
Rhodopsin kinase
Ryanodine receptor 1
Ryanodine receptor 2
S-protein
Serine/threonine-protein kinase Sgk1
Serotonin acetylase
SNARE-associated protein Snapin
Sodium bicarbonate cotransporter
Sodium channel protein
Sodium channel protein type II alpha subunit
Solute carrier family,member 2
SOX9
spdya-A
Src
Stathmin
STK24
Sucrase isomaltase
Synapsin II
Synapsin-1
TAL-1 protein
tau
TBXA2R
Thimet oligopeptidase 1
Thyroid hormone receptor alpha
Transforming protein RhoA
Troponin I, cardiac muscle
Troponin I, fast skeletal muscle
Tryptophan 5-hydroxylase 1
Tumor necrosis factor receptor superfamily member 16
Tyr-3-hydroxylase
Tyrosine-protein phosphatase, non-receptor type 12
Tyrosine-protein phosphatase, non-receptor type 7
UNC84B
VASP
Vimentin
vitamin D receptor
Voltage-dependent L-type calcium channel alpha-1C subunit
Voltage-dependent L-type calcium channel alpha-1S subunit
Voltage-dependent L-type calcium channel beta-2 subunit
Wilm tumor protein

Substrate:

14-3-3 zeta/delta (14-3-3 protein zeta/delta (Protein kinase C inhibitor protein-1) (KCIP-1) (Factor activating exoenzyme S) (FAS))

Seq-ID:

P63104 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14323   FOXO3_HUMAN
MINT-14772   PRLR_HUMAN
MINT-17015   IL9R_HUMAN
MINT-17278   KC1A_HUMAN
MINT-17367   TPD53_HUMAN
MINT-17571   RIN1_HUMAN
MINT-17818   ATX1_HUMAN
MINT-19329   MPIP2_HUMAN
MINT-19336   ADA23_HUMAN
MINT-45800   RAF1_HUMAN
MINT-48206   NEMO_HUMAN
MINT-48480   M3K3_HUMAN
MINT-50358   HSP71_HUMAN
MINT-50935   EGFR_HUMAN
MINT-51005   IF4A3_HUMAN
MINT-51010   TRA2B_HUMAN
MINT-51012   DFFA_HUMAN
MINT-51013   STK38_HUMAN
MINT-51018   E41L3_HUMAN
MINT-51019   MEP50_HUMAN
MINT-51020   RO52_HUMAN
MINT-51021   TBB5_HUMAN
MINT-51022   ZO2_HUMAN
MINT-51025   KLC4_HUMAN
MINT-51027   Q8IXP7_HUMAN
MINT-51051   K1C19_HUMAN
MINT-51052   K1C18_HUMAN
MINT-63980   KU70_HUMAN
MINT-74924   KAPCA_HUMAN
MINT-74925   P53_HUMAN
MINT-3294407   MPIP1_HUMAN
MINT-3294433   MPIP3_HUMAN
MINT-3294883   MARK2_HUMAN
MINT-3295089   NUMA1_HUMAN
MINT-3295217   PCM1_HUMAN
MINT-3295255   NDE1_HUMAN
MINT-3295375   WEE1_HUMAN
MINT-3295392   CDK18_HUMAN
MINT-3295415   CDK17_HUMAN
MINT-3295530   MARK3_HUMAN
MINT-3295552   BRAF_HUMAN
MINT-3295573   MPRIP_HUMAN
MINT-3295597   ARHG2_HUMAN
MINT-3295618   RHG21_HUMAN
MINT-3295674   GAPD1_HUMAN
MINT-3295696   ARHGG_HUMAN
MINT-3295740   ATLA2_HUMAN
MINT-3295774   LIPB1_HUMAN
MINT-3295882   IRS2_HUMAN
MINT-3295899   PDE3A_HUMAN
MINT-3295953   LIMA1_HUMAN
MINT-3295975   CALM_HUMAN
MINT-3295996   PARD3_HUMAN
MINT-3296030   SI1L3_HUMAN
MINT-3296068   APC_HUMAN
MINT-3296095   NOLC1_HUMAN
MINT-3296132   NUCL_HUMAN
MINT-3296152   NPM_HUMAN
MINT-3296187   PSMD2_HUMAN
MINT-3296221   THIO_HUMAN
MINT-3296237   PRDX1_HUMAN
MINT-3296270   CE170_HUMAN
MINT-3296359   PYRG1_HUMAN
MINT-3296408   NADK_HUMAN
MINT-3296440   NDKB_HUMAN
MINT-3296457   KITH_HUMAN
MINT-3296491   HDAC4_HUMAN
MINT-3296507   HDAC7_HUMAN
MINT-3296523   YBOX1_HUMAN
MINT-3296639   HAT1_HUMAN
MINT-3296655   H4_HUMAN
MINT-3296701   H2A1_HUMAN
MINT-3296729   SPT6H_HUMAN
MINT-3296749   DNMT1_HUMAN
MINT-3296781   RUVB2_HUMAN
MINT-3296831   HNRPF_HUMAN
MINT-3296856   HNRH2_HUMAN
MINT-3296872   HNRPK_HUMAN
MINT-3296888   PCBP1_HUMAN
MINT-3296904   HNRPC_HUMAN
MINT-3296922   ROA1_HUMAN
MINT-3296956   DDX1_HUMAN
MINT-3296972   DDX3X_HUMAN
MINT-3297068   LA_HUMAN
MINT-3297088   RS3_HUMAN
MINT-3297112   RLA0_HUMAN
MINT-3297147   RL19_HUMAN
MINT-3297169   RL5_HUMAN
MINT-3297185   RLA2_HUMAN
MINT-3297202   RS7_HUMAN
MINT-3297276   SYEP_HUMAN
MINT-3297301   PABP2_HUMAN
MINT-3297322   PABP4_HUMAN
MINT-3297360   GCN1L_HUMAN
MINT-3297377   IF4G1_HUMAN
MINT-3297431   EIF3F_HUMAN
MINT-3297456   EF2_HUMAN
MINT-3297472   EF1A1_HUMAN
MINT-3297494   EF1B_HUMAN
MINT-3297642   KINH_HUMAN
MINT-3297660   KLC2_HUMAN
MINT-3297714   DYHC1_HUMAN
MINT-3297730   TBA1B_HUMAN
MINT-3297793   VIME_HUMAN
MINT-3297814   LMNA_HUMAN
MINT-3297843   LMNB1_HUMAN
MINT-3297866   ANXA2_HUMAN
MINT-3297886   ANXA1_HUMAN
MINT-3297917   ACTB_HUMAN
MINT-3297984   TLN1_HUMAN
MINT-3298006   FSCN1_HUMAN
MINT-3298028   HAKAI_HUMAN
MINT-3298189   PROF1_HUMAN
MINT-3298215   COF1_HUMAN
MINT-3304213   K6PP_HUMAN
MINT-3304235   F262_HUMAN
MINT-3304340   FAS_HUMAN
MINT-3304385   ACSL4_HUMAN
MINT-3304469   G3P_HUMAN
MINT-3304487   KCRU_HUMAN
MINT-3304522   LDHB_HUMAN
MINT-3304540   LDHA_HUMAN
MINT-3304560   SPRE_HUMAN
MINT-3304637   KPYM_HUMAN
MINT-3304676   TKT_HUMAN
MINT-3304695   ALDOA_HUMAN
MINT-3304712   ENOA_HUMAN
MINT-3304765   TPIS_HUMAN
MINT-3304790   TCPQ_HUMAN
MINT-3304899   TCPA_HUMAN
MINT-3305086   CH60_HUMAN
MINT-3305120   GRP78_HUMAN
MINT-3305183   HS90A_HUMAN
MINT-3305276   HS105_HUMAN
MINT-3305331   HSPB1_HUMAN
MINT-3305423   PPIA_HUMAN
MINT-3305616   TRAP1_HUMAN
MINT-3305679   HS71L_HUMAN
MINT-3305799   IPO7_HUMAN
MINT-3305862   IMB1_HUMAN
MINT-3306240   TIF1B_HUMAN
MINT-3306314   CIC_HUMAN
MINT-3306548   LMO7_HUMAN
MINT-3306606   VIR_HUMAN
MINT-3306625   FL2D_HUMAN
MINT-3306813   ZC3HD_HUMAN
MINT-3307270   PERQ2_HUMAN
MINT-3307331   LARP1_HUMAN
MINT-3307383   FNBP2_HUMAN
MINT-3307403   SMAG2_HUMAN
MINT-3307456   TERA_HUMAN
MINT-3307546   TPD52_HUMAN
MINT-3307735   MYCB2_HUMAN
MINT-3307756   MCM3_HUMAN
MINT-3307783   ASPP2_HUMAN
MINT-3307813   P3C2B_HUMAN
MINT-3307838   FRAP_HUMAN
MINT-3308034   PAK4_HUMAN
MINT-3308059   RPGF2_HUMAN
MINT-3308248   IQGA1_HUMAN
MINT-3308267   RPGP1_HUMAN
MINT-3308328   ATLA3_HUMAN
MINT-3308436   SRGP1_HUMAN
MINT-3308521   AFAD_HUMAN
MINT-3308685   LIPB1_HUMAN
MINT-3317863   TSC2_HUMAN
MINT-3317888   AKTS1_HUMAN
MINT-3317913   PTN3_HUMAN
MINT-3317930   YAP1_HUMAN
MINT-3317972   SH3B4_HUMAN
MINT-3317988   PSMD1_HUMAN
MINT-3318133   UBP8_HUMAN
MINT-3318149   CAND1_HUMAN
MINT-3318217   UBA1_HUMAN
MINT-3318321   PYR1_HUMAN
MINT-3318337   HDAC5_HUMAN
MINT-3318368   PRI2_HUMAN
MINT-3318428   PTBP1_HUMAN
MINT-3318458   HNRPU_HUMAN
MINT-3318488   DCP1A_HUMAN
MINT-3318520   DHX9_HUMAN
MINT-3318572   SRRM2_HUMAN
MINT-3318588   SYVC_HUMAN
MINT-3318610   SYIC_HUMAN
MINT-3318644   SYAC_HUMAN
MINT-3318676   EIF3A_HUMAN
MINT-3318692   IF4A1_HUMAN
MINT-3318708   KIF23_HUMAN
MINT-3318724   KLC3_HUMAN
MINT-3318808   FLNA_HUMAN
MINT-3318838   CING_HUMAN
MINT-3318854   AHNK_HUMAN
MINT-3318871   DESP_HUMAN
MINT-3318887   EZRI_HUMAN
MINT-3318904   SPTA2_HUMAN
MINT-3318920   SPTB2_HUMAN
MINT-3318937   VINC_HUMAN
MINT-3318960   ACTN4_HUMAN
MINT-3318976   PGAM1_HUMAN
MINT-3319004   PGK1_HUMAN
MINT-3319021   S27A2_HUMAN
MINT-3319127   PANK2_HUMAN
MINT-3319198   PURA1_HUMAN
MINT-3319239   CGL_HUMAN
MINT-3319281   TFR1_HUMAN
MINT-3319320   GRP75_HUMAN
MINT-3319337   HSP7C_HUMAN
MINT-3319393   FKBP4_HUMAN
MINT-3319394   HSP74_HUMAN
MINT-3319575   HS90B_HUMAN
MINT-3319592   XPO1_HUMAN
MINT-3319626   NFAC1_HUMAN
MINT-3319708   NUFP1_HUMAN
MINT-3319791   SET_HUMAN
MINT-3319822   CV028_HUMAN
MINT-3319865   TBCD4_HUMAN
MINT-3319899   KIBRA_HUMAN
MINT-3319917   RAI14_HUMAN
MINT-3319945   MVP_HUMAN
MINT-3319979   1433S_HUMAN
MINT-3319998   ESYT1_HUMAN
MINT-3320046   EDC3_HUMAN
MINT-3320063   MYCPP_HUMAN
MINT-3320079   CLH1_HUMAN
MINT-3320095   MYOF_HUMAN
MINT-3320159   SCAM2_HUMAN
MINT-7262288   KPCE_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein domain specific binding, transcription factor binding	melanosome	anti-apoptosis, signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	58	YKNVVGARRSSWRVVSSIEQK	PKA_group	16376338	LTP	-	MOD_PKA_1	-	14_3_3	0.30	2O02	45.90%

Substrate:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, (from PhosphoBase))

Seq-ID:

P07953 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
6-phosphofructo-2-kinase activity, fructose-2,6-bisphosphate 2-phosphatase activity, identical protein binding, ATP binding, kinase binding, fructose-6-phosphate binding	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex	fructose 2,6-bisphosphate metabolic process, response to cAMP, positive regulation of glucokinase activity, organ regeneration, response to insulin stimulus, response to glucagon stimulus, response to glucocorticoid stimulus, response to starvation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	33	SSSVLQRRRGSSIPQFTNSPT	PKA_group	6330071	LTP	0.44	MOD_PKA_1	-	6PF2K	0.49	-	low

Substrate:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Enzyme: Phosphotransferase)

Seq-ID:

P26285 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
6-phosphofructo-2-kinase activity, fructose-2,6-bisphosphate 2-phosphatase activity, ATP binding		fructose 2,6-bisphosphate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	467	SQTPVRMRRNSFTPLSSSNTI	PKA_group	2846551	LTP	0.61	MOD_PKA_1	-	-	0.68	-	low

Substrate:

6-phosphofructokinase, liver type (6-phosphofructokinase, liver type (from PhosphoBase))

Seq-ID:

P17858 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48115   IKKE_HUMAN
MINT-48463   M3K3_HUMAN
MINT-49011   RELB_HUMAN
MINT-49206   TAB2_HUMAN
MINT-61849   PR40A_HUMAN
MINT-2861721   ATN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
identical protein binding, metal ion binding, ATP binding, kinase binding, fructose-6-phosphate binding, 6-phosphofructokinase activity	6-phosphofructokinase complex	fructose 6-phosphate metabolic process, protein oligomerization, glycolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	773	SGELEHVTRRTLSMDKGF	PKA_group	8670219	LTP	0.15	MOD_PKA_2	-	-	0.27	-	medium

Substrate:

6-phosphofructokinase, muscle type (6-phosphofructokinase, muscle type (from PhosphoBase))

Seq-ID:

P00511 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein C-terminus binding, metal ion binding, ATP binding, 6-phosphofructokinase activity	6-phosphofructokinase complex	glycolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	377	FDEAMKLRGRSFMNNWEVYKL	PKA_group	1825608	LTP	0.98		-	-	0.18	-	medium
S	775	AHLEHISRKRSGEATV	PKA_group	1825608	LTP	0.22	MOD_PKA_1	-	-	0.50	-	medium

Substrate:

A-kinase anchoring protein. (kinase activity, Rho guanyl-nucleotide exchange factor activity)

Seq-ID:

Q12802 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, cAMP-dependent protein kinase activity, metal ion binding, signal transducer activity, protein binding	membrane fraction, cytosol, nucleus, membrane	induction of apoptosis by extracellular signals, apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1565	MRSLSPFRRHSWGPGKNAASD	PKA_group	15229649	LTP	-	MOD_PKA_1	-	-	0.66	-	medium
S	2733	SELSVSPKRNSISRTHKDKGP	PKA_group	15383279	LTP	-	MOD_PKA_1	-	-	0.79	-	medium

Substrate:

Acetyl-CoA carboxylase 1 (Enzyme: Carboxylase)

Seq-ID:

P11497 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, acetyl-CoA carboxylase activity, biotin carboxylase activity, ATP binding, biotin binding	soluble fraction	response to organic cyclic substance, acetyl-CoA metabolic process, response to drug, fatty acid biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	77	QDGLAFHMRSSMSGLHLVKQG	PKA_group	2900138	LTP	0.16	MOD_PKA_2	-	-	0.30	-	low
S	1200	RGNIPTLNRMSFASNLNHYGM	PKA_group	7915280	LTP	0.83	MOD_PKA_2	-	ACC_central	0.27	-	low
S	1200	RGNIPTLNRMSFASNLNHYGM	PKA_group	2900138	LTP	0.83	MOD_PKA_2	-	ACC_central	0.27	-	low

Substrate:

Acetylcholine receptor protein, delta chain (Acetylcholine receptor)

Seq-ID:

P02718 [Torpedo californica]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nicotinic acetylcholine-activated cation-selective channel activity, receptor activity	cell junction, integral to membrane, postsynaptic membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	381	DWQNDLKLRRSSSVGYISKAQ	PKA_group	3038884	LTP	0.23	MOD_PKA_1	-	Neur_chan_memb	0.25	-	medium
S	382	WQNDLKLRRSSSVGYISKAQE	PKA_group	3038884	LTP	1.00	MOD_PKA_1	-	Neur_chan_memb	0.22	-	medium
S	383	QNDLKLRRSSSVGYISKAQEY	PKA_group	3038884	LTP	1.00	MOD_PKA_1	-	Neur_chan_memb	0.19	-	medium

Substrate:

ADR1 (regulatory protein ADR1 (from PhosphoBase))

Seq-ID:

P07248 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7929868 FUS3_YEAST

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	transcription, peroxisome organization, regulation of carbohydrate metabolic process, negative regulation of transcription from RNA polymerase II promoter by glucose

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	230	KYLKKLTRRASFSAQSASSYA	PKA_group	2644045	LTP	1.00	MOD_PKA_1	-	-	0.41	-	low
S	230	KYLKKLTRRASFSAQSASSYA	PKA_group	8910470	LTP	1.00	MOD_PKA_1	-	-	0.41	-	low

Substrate:

Alpha adducin (Structural protein)

Seq-ID:

P35611 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-72730 RFX1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
spectrin binding, protein heterodimerization activity, protein homodimerization activity, metal ion binding, transcription factor binding, calmodulin binding, actin filament binding	plasma membrane, cytosol, F-actin capping protein complex, nucleus	positive regulation of protein binding, actin filament bundle assembly, barbed-end actin filament capping

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	59	FNMMEQKKRVSMILQSPAFCE	PKA_group	8810272	LTP	1.00	MOD_PKA_1	-	-	0.35	-	medium
S	408	PALREKSKKYSDVEVPASVTG	PKA_group	8810272	LTP	1.00	MOD_PKA_1	-	-	0.46	-	medium
S	436	DSGTCSPLRHSFQKQQREKTR	PKA_group	8810272	LTP	0.10	MOD_PKA_2	-	-	0.65	-	medium
S	481	KWTKEDGHRTSTSAVPNLFVP	PKA_group	8810272	LTP	0.67	MOD_PKA_2	-	-	0.61	-	medium

Substrate:

APC (Adhesion molecule)

Seq-ID:

P25054 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1780719   DLG4_MOUSE
MINT-3296068   1433Z_HUMAN
MINT-3975353   1433S_HUMAN
MINT-4508229   CTNB1_HUMAN
MINT-6732416   SCRIB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
microtubule plus-end binding, protein kinase regulator activity, protein kinase binding, beta-catenin binding, gamma-catenin binding	centrosome, Axin-APC-beta-catenin-GSK3B complex, beta-catenin destruction complex, cytosol, lateral plasma membrane, kinetochore, adherens junction, nucleus, tight junction	negative regulation of cyclin-dependent protein kinase activity, positive regulation of protein catabolic process, protein complex assembly, positive regulation of cell migration, positive regulation of pseudopodium assembly, cell cycle arrest, cytokinesis after mitosis, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of apoptosis, canonical Wnt receptor signaling pathway, negative regulation of microtubule depolymerization, regulation of attachment of spindle microtubules to kinetochore, response to DNA damage stimulus, cell adhesion, tight junction assembly, mitotic cell cycle spindle assembly checkpoint

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2054	SSAMPKKKKPSRLKGDNEKHS	PKA_group	11050185	LTP	0.11	MOD_PKA_1	-	-	0.81	-	medium

Substrate:

Aquaporin 0 (Water channel. Transporter activity)

Seq-ID:

P06624 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of eye lens	gap junction, integral to membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	243	RLSILKGSRPSESNGQPEVTG	PKA_group	2176601	LTP	0.36	MOD_PKA_2	-	-	0.55	-	-

Substrate:

Aquaporin 0 (Water channel. Transporter activity)

Seq-ID:

P30301 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of eye lens	gap junction, integral to plasma membrane	visual perception, response to stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	229	YDFLLFPRLKSISERLSVLKG	PKA_group	2176601	LTP	0.27		-	-	0.03	-	medium
S	231	FLLFPRLKSISERLSVLKGAK	PKA_group	2176601	LTP	0.96		-	-	0.06	-	medium

Substrate:

Aquaporin 2 (Water channel)

Seq-ID:

P41181 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
glycerol transmembrane transporter activity, water channel activity	integral to membrane, cytoplasmic vesicle membrane, apical plasma membrane	excretion, cellular response to copper ion, cellular response to mercury ion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	256	WEEREVRRRQSVELHSPQSLP	PKA_group	10710543	LTP	0.37	MOD_PKA_1	-	-	0.54	-	medium

Substrate:

Arachidonate 5 lipoxygenase (Enzyme: Lipase)

Seq-ID:

P09917 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
arachidonate 5-lipoxygenase activity, iron ion binding, lipoxygenase activity, protein binding	nuclear envelope lumen, cytosol, nuclear membrane, nuclear matrix	oxidation reduction, leukotriene biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	272	MVECSLERQLSLEQEVQQGNI	PKA_group	11844797	LTP	0.64		-	Lipoxygenase	0.18	-	high
S	524	YVYGMRGRKSSGFPKSVKSRE	PKA_group	16230355	LTP	0.90	MOD_PKA_1	-	Lipoxygenase	0.32	-	high
S	524	YVYGMRGRKSSGFPKSVKSRE	PKA_group	15280375	LTP	0.90	MOD_PKA_1	-	Lipoxygenase	0.32	-	high

Substrate:

ATP-binding cassette 1 (Transport/cargo protein)

Seq-ID:

O95477 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-59503 SNTB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATPase activity, anion transmembrane transporter activity, apolipoprotein A-I receptor activity, small GTPase binding, cholesterol binding, phospholipid binding, ATP binding, phospholipid transporter activity, syntaxin-13 binding, cholesterol transporter activity	membrane fraction, integral to plasma membrane, phagocytic vesicle, membrane raft	positive regulation of cAMP biosynthetic process, platelet dense granule organization, high-density lipoprotein particle assembly, cholesterol homeostasis, endosome transport, phospholipid homeostasis, lysosome organization, negative regulation of macrophage derived foam cell differentiation, phospholipid efflux, negative regulation of cholesterol storage, reverse cholesterol transport, Cdc42 protein signal transduction, cholesterol efflux, cholesterol metabolic process, interleukin-1 beta secretion, intracellular cholesterol transport, G-protein coupled receptor protein signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1042	QLSGGMQRKLSVALAFVGGSK	PKA_group	12196520	LTP	1.00	MOD_PKA_1	-	AAA	0.13	-	medium
S	2054	NYSGGNKRKLSTAMALIGGPP	PKA_group	12196520	LTP	1.00	MOD_PKA_1	-	AAA	0.29	-	medium

Substrate:

ATP-citrate synthase (ATPase)

Seq-ID:

P16638 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP citrate synthase activity, metal ion binding, ATP binding, succinate-CoA ligase (ADP-forming) activity	cytoplasm, soluble fraction	fatty acid biosynthetic process, acetyl-CoA biosynthetic process, citrate metabolic process, cellular carbohydrate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	454	TSTPAPSRTASFSESRADEVA	PKA_group	6286669	LTP	0.68		-	-	0.72	-	low

Substrate:

ATP-citrate synthase (ATPase)

Seq-ID:

P53396 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP citrate synthase activity, metal ion binding, ATP binding, succinate-CoA ligase (ADP-forming) activity, citrate (pro-3S)-lyase activity, protein binding	cytosol, citrate lyase complex	coenzyme A metabolic process, ATP catabolic process, citrate metabolic process, cellular carbohydrate metabolic process, lipid biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	455	TSTPAPSRTASFSESRADEVA	PKA_group	10653665	LTP	0.68		-	-	0.73	-	medium

Substrate:

Aurora kinase A (Serine/threonine kinase)

Seq-ID:

O14965 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, protein kinase binding, ATP binding	spindle microtubule, nucleus, spindle pole centrosome	protein amino acid phosphorylation, cell division, phosphoinositide-mediated signaling, mitosis, spindle organization, regulation of protein stability

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	288	SVHAPSSRRTTLCGTLDYLPP	PKA_group	11039908	LTP	1.00	MOD_PKA_1	-	S_TKc	0.28	1MQ4	33.56%

Substrate:

Aurora-C (Ser/Thr protein kinase family)

Seq-ID:

O88445 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding	chromosome, centromeric region, cytoplasm, spindle pole	protein amino acid phosphorylation, cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	171	SVHTPSLRRKTMCGTLDYLPP	PKA_group	11879579	LTP	0.97	MOD_PKA_1	-	S_TKc	0.25	-	low
T	175	PSLRRKTMCGTLDYLPPEMIA	PKA_group	11879579	LTP	0.97		-	S_TKc	0.29	-	low

Substrate:

B-Raf (B-Raf proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P15056 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50344   1433B_HUMAN
MINT-50372   1433T_HUMAN
MINT-2833162   KPCA_HUMAN
MINT-2833238   KPCE_HUMAN
MINT-2833314   KS6A2_HUMAN
MINT-3295552   1433Z_HUMAN
MINT-3374124   M3K1_HUMAN
MINT-3975375   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, ATP binding	cytoplasm, nucleus	protein amino acid phosphorylation, organ morphogenesis, anti-apoptosis, small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	429	SPGPQRERKSSSSSEDRNRMK	PKA_group	11510412	LTP	1.00	MOD_PKA_1	-	-	0.92	-	-

Substrate:

BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))

Seq-ID:

Q92934 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14699   B2CL1_HUMAN
MINT-66103   1433S_HUMAN
MINT-7034091   B2L11_HUMAN
MINT-7717137   NAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding	cytosol, mitochondrial outer membrane	induction of apoptosis by extracellular signals, activation of pro-apoptotic gene products

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	75	GAVEIRSRHSSYPAGTEDDEG	PKA_group	15226424	LTP	0.32	MOD_PKA_2	-	Bcl-2_BAD	0.83	-	medium

Substrate:

Beta adducin (Anchor protein)

Seq-ID:

P35612 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
spectrin binding, protein heterodimerization activity, protein homodimerization activity, metal ion binding, calmodulin binding, actin filament binding	plasma membrane, cytoplasm, F-actin capping protein complex	positive regulation of protein binding, actin filament bundle assembly, barbed-end actin filament capping

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	55	FNLMEQKKRVTMILQSPSFRE	PKA_group	8810272	LTP	0.95	MOD_PKA_1	-	-	0.40	-	medium

Substrate:

Beta casein precursor (beta casein (from PhosphoBase))

Seq-ID:

P02666 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
antioxidant activity, transporter activity, metalloendopeptidase inhibitor activity	extracellular region	regulation of blood pressure

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	139	YPVEPFTESQSLTLTDVENLH	PKA_group	1059131	LTP	0.19		-	Casein	0.47	-	low

Substrate:

Beta-2 adrenergic receptor (Protein G coupled receptor)

Seq-ID:

P07550 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1796656   NHRF1_HUMAN
MINT-4051815   SRC_HUMAN
MINT-7291631   UBP33_HUMAN
MINT-7720120   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
potassium channel regulator activity, protein homodimerization activity, norepinephrine binding, beta2-adrenergic receptor activity	receptor complex, endosome, integral to plasma membrane, lysosome	positive regulation of MAPKKK cascade, receptor-mediated endocytosis, activation of transmembrane receptor protein tyrosine kinase activity, endosome to lysosome transport, desensitization of G-protein coupled receptor protein signaling pathway by arrestin

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	262	GRTGHGLRRSSKFCLKEHKAL	PKA_group	11146000	LTP	1.00	MOD_PKA_1	-	7tm_1	0.20	-	-
S	345	AFQELLCLRRSSLKAYGNGYS	PKA_group	11146000	LTP	0.14	MOD_PKA_1	-	-	0.08	2R4R	83.61%
S	346	FQELLCLRRSSLKAYGNGYSS	PKA_group	11146000	LTP	0.18	MOD_PKA_1	-	-	0.10	2R4R	28.69%

Substrate:

Beta-ARK-1 (Beta-adrenergic receptor kinase)

Seq-ID:

P25098 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51490   EGFR_HUMAN
MINT-3376147   MDM2_HUMAN
MINT-6608788   GIT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
G-protein coupled receptor kinase activity, ATP binding, Edg-2 lysophosphatidic acid receptor binding, alpha-2A adrenergic receptor binding, beta-adrenergic receptor kinase activity, signal transducer activity	cytosol, soluble fraction	negative regulation of striated muscle contraction, desensitization of G-protein coupled receptor protein signaling pathway, positive regulation of catecholamine secretion, muscarinic acetylcholine receptor signaling pathway, tachykinin receptor signaling pathway, peptidyl-serine phosphorylation, cardiac muscle contraction, negative regulation of the force of heart contraction by chemical signal

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	685	LSKVPLVQRGSANGL	PKA_group	11278469	LTP	0.26	MOD_PKA_2	-	-	0.36	-	-

Substrate:

Brain sodium channel 2 (Ion channel, other)

Seq-ID:

P78348 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amiloride-sensitive sodium channel activity, protein binding	integral to plasma membrane	response to pH, signal transduction, calcium ion transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	479	GKCQKEAKRSSADKGVALSLD	PKA_group	12578970	LTP	0.41	MOD_PKA_1	-	-	0.33	-	high

Substrate:

C/EBP beta (Transcription factor)

Seq-ID:

P17676 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14023   SMAD3_HUMAN
MINT-14687   SMAD4_HUMAN
MINT-49733   HMGA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
RNA polymerase II transcription factor activity, enhancer binding		transcription from RNA polymerase II promoter, immune response, acute-phase response

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	288	RERNNIAVRKSRDKAKMRNLE	PKA_group	9374525	LTP	1.00	MOD_PKA_2	-	COIL	0.73	2E42	62.30%

Substrate:

CAD (carbamoyl-phosphate synthase (glutamine-hyd...)

Seq-ID:

P27708 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48168   NEMO_HUMAN
MINT-48300   M3K1_HUMAN
MINT-48426   M3K3_HUMAN
MINT-48660   NFKB1_HUMAN
MINT-48723   NFKB2_HUMAN
MINT-48821   M3K14_HUMAN
MINT-48995   RELB_HUMAN
MINT-49046   RIPK1_HUMAN
MINT-49196   TAB2_HUMAN
MINT-49403   TNR1B_HUMAN
MINT-3318321   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
aspartate carbamoyltransferase activity, dihydroorotase activity, carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, metal ion binding, ATP binding, enzyme binding, protein kinase activity, aspartate binding	cytosol, nuclear matrix	`de novo` pyrimidine base biosynthetic process, protein amino acid autophosphorylation, pyrimidine nucleotide biosynthetic process, peptidyl-threonine phosphorylation, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1406	SMRGAGGRRLSSFVTKGYRTR	PKA_group	17206380	LTP	1.00	MOD_PKA_1	-	MGS	0.28	-	medium
S	1406	SMRGAGGRRLSSFVTKGYRTR	PKA_group	14991569	LTP	1.00	MOD_PKA_1	-	MGS	0.28	-	medium
S	1406	SMRGAGGRRLSSFVTKGYRTR	PKA_group	17485345	LTP	1.00	MOD_PKA_1	-	MGS	0.28	-	medium

Substrate:

Calcium/calmodulin-dependent protein kinase kinase 1 (Ser/Thr protein kinase family)

Seq-ID:

Q8N5S9 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6491300 1433F_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP binding, calmodulin-dependent protein kinase activity, calmodulin binding	cytosol, nucleus	protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	108	HISPRAWRRPTIESHHVAISD	PKA_group	10187789	LTP	1.00	MOD_PKA_1	-	-	0.51	-	medium

Substrate:

cAMP-dependent protein kinase regulatory subunit (cAMP-dependent protein kinase regulatory chain (from PhosphoBase))

Seq-ID:

P07278 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, identical protein binding, cAMP-dependent protein kinase regulator activity, cAMP-dependent protein kinase inhibitor activity	plasma membrane, cAMP-dependent protein kinase complex, cytoplasm, nucleus	negative regulation of Ras protein signal transduction, signal transduction, regulation of protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	145	PMHFNAQRRTSVSGETLQPNN	PKA_group	1956339	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium

Substrate:

cAMP-dependent protein kinase type II-alpha regulatory subunit (cAMP-dependent protein kinase type II-alpha regulatory chain)

Seq-ID:

P00515 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-1779097 CSK21_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	cAMP-dependent protein kinase complex	signal transduction, regulation of protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	96	PIPGRFDRRVSVCAETYNPDE	PKA_group	4367815	LTP	0.96	MOD_PKA_1	-	-	0.52	-	medium

Substrate:

cAMP-dependent protein kinase type II-alpha regulatory subunit (cAMP-dependent protein kinase type II-alpha regulatory chain)

Seq-ID:

P13861 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-2411858   AKA12_HUMAN
MINT-2411925   AKAP1_HUMAN
MINT-2983605   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	membrane fraction, cytosol	intracellular signaling pathway, signal transduction, activation of protein kinase A activity, regulation of protein amino acid phosphorylation, hormone-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	99	PVPSRFNRRVSVCAETYNPDE	PKA_group	11263724	LTP	0.97	MOD_PKA_1	-	-	0.53	-	low

Substrate:

cAMP-dependent protein kinase type II-beta regulatory subunit (cAMP-dependent protein kinase type II-beta regulatory chain)

Seq-ID:

P31322 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding	cAMP-dependent protein kinase complex	signal transduction, regulation of protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	114	PVINRFTRRASVCAEAYNPDE	PKA_group	4030778	LTP	0.98	MOD_PKA_1	-	-	0.45	-	low

Substrate:

cAMP-dependent protein kinase type II-beta regulatory subunit (cAMP-dependent protein kinase type II-beta regulatory chain)

Seq-ID:

P31323 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	cytosol	intracellular signaling pathway, signal transduction, activation of protein kinase A activity, regulation of protein amino acid phosphorylation, hormone-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	114	PVINRFTRRASVCAEAYNPDE	PKA_group	7479855	LTP	0.98	MOD_PKA_1	-	-	0.44	-	medium

Substrate:

cAMP-dependent protein kinase, alpha-catalytic subunit (cAMP-dependent protein kinase)

Seq-ID:

P00517 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP-dependent protein kinase activity, ATP binding	neuromuscular junction, nucleus	mesoderm formation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	198	FAKRVKGRTWTLCGTPEYLAP	PKA_group	221492	LTP	0.95		-	S_TKc	0.09	1XH9	48.63%
S	339	DDYEEEEIRVSINEKCGKEFS	PKA_group	6262777	LTP	0.85	MOD_PKA_2	-	S_TK_X	0.30	1XH9	74.59%

Substrate:

CAPN2 (cysteine-type peptidase activity)

Seq-ID:

P17655 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1795337 NMT1_HUMAN
MINT-6793394 PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	plasma membrane, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	369	TKMDGNWRRGSTAGGCRNYPN	PKA_group	11909964	LTP	0.98	MOD_PKA_1	-	calpain_III	0.41	1KFX	7.38%
T	370	KMDGNWRRGSTAGGCRNYPNT	PKA_group	11909964	LTP	1.00	MOD_PKA_1	-	calpain_III	0.41	1KFX	0.00%

Substrate:

Casein kinase I, delta isoform (casein kinase I activity)

Seq-ID:

Q06486 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-3389911   SNAPN_MOUSE
MINT-3390028   P53_HUMAN
MINT-3390055   MAP4_HUMAN
MINT-3390085   TAU_HUMAN
MINT-3390466   MAP1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, peptide binding, glycoprotein binding, ATP binding, phosphoprotein binding	centrosome, spindle, soluble fraction, nucleus	protein amino acid phosphorylation, mitotic cell cycle, regulation of circadian rhythm, circadian regulation of gene expression, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Wnt receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	370	VSGMERERKVSMRLHRGAPVN	PKA_group	17594292	LTP	0.64	MOD_PKA_1	-	-	0.76	-	low

Substrate:

CD243 (multidrug resistance protein 1 (P-glycoprotein 1) (from PhosphoBase))

Seq-ID:

P08183 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-50920 CAV1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
xenobiotic-transporting ATPase activity, ATP binding, protein binding	membrane fraction, cell surface, integral to membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	667	DSRSSLIRKRSTRRSVRGSQA	PKA_group	8132598	LTP	0.92	MOD_PKA_1	-	-	0.51	-	medium
S	683	RGSQAQDRKLSTKEALDESIP	PKA_group	8132598	LTP	0.39	MOD_PKA_1	-	-	0.44	-	medium

Substrate:

CD42C (platelet glycoprotein IB beta chain precursor (GP-IB beta) (from PhosphoBase))

Seq-ID:

P13224 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transmembrane receptor activity, protein binding	integral to plasma membrane, platelet alpha granule membrane	cell surface receptor linked signaling pathway, cell adhesion, platelet activation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	191	RARARAAARLSLTDPLVAERA	PKA_group	2504723	LTP	0.79	MOD_PKA_2	YWHAZ 14-3-3	-	0.22	-	medium

Substrate:

CD91 (Cell surface receptor)

Seq-ID:

Q07954 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, calcium ion binding, lipid transporter activity, lipoprotein binding, lipoprotein receptor binding, apolipoprotein binding, protein complex binding	membrane fraction, integral to plasma membrane, coated pit, nucleus	lipid metabolic process, regulation of phospholipase A2 activity, negative regulation of Wnt receptor signaling pathway, positive regulation of cholesterol efflux, apoptotic cell clearance, multicellular organismal development, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	4517	YATLYMGGHGSRHSLASTDEK	PKA_group	11158305	LTP	0.11	MOD_PKA_2	-	-	0.41	-	low
S	4520	LYMGGHGSRHSLASTDEKREL	PKA_group	12069755	LTP	0.23	MOD_PKA_2	-	-	0.49	-	low

Substrate:

Centrin 1 (Calcium binding protein)

Seq-ID:

Q12798 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, ATP-dependent helicase activity, ATP binding, nucleic acid binding	spindle pole	cell division, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	170	EEFLRIMKKTSLY	PKA_group	11279195	LTP	0.03		-	-	0.18	-	low

Substrate:

CETN2 (calcium ion binding, protein binding)

Seq-ID:

P41208 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, ATP-dependent helicase activity, ATP binding, nucleic acid binding	cytosol, centriole	cell division, centriole replication, regulation of cytokinesis, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	170	QEFLRIMKKTSLY	PKA_group	11279195	LTP	0.05		-	-	0.18	-	-

Substrate:

CFTR (cystic fibrosis transmembrane conductance regulator (CFTR) (from PhosphoBase))

Seq-ID:

P13569 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-60075   NHRF1_MOUSE
MINT-69537   BCR_HUMAN
MINT-73263   NHRF3_MOUSE
MINT-1783772   GOPC_HUMAN
MINT-1787402   NHRF2_HUMAN
MINT-1794992   CALX_HUMAN
MINT-1796681   NHRF1_HUMAN
MINT-7218998   UBP19_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
channel-conductance-controlling ATPase activity, ATP-binding and phosphorylation-dependent chloride channel activity, ATP binding, enzyme binding, PDZ domain binding	early endosome membrane, basolateral plasma membrane, chloride channel complex, apical plasma membrane	respiratory gaseous exchange

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	660	FDQFSAERRNSILTETLHRFS	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.28	2BBS	43.44%
S	700	TGEFGEKRKNSILNPINSIRK	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.41	-	-
S	737	DSDEPLERRLSLVPDSEQGEA	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.64	-	-
S	753	EQGEAILPRISVISTGPTLQA	PKA_group	7530719	LTP	0.34	MOD_PKA_2	-	-	0.48	-	-
S	768	GPTLQARRRQSVLNLMTHSVN	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.46	-	-
S	795	RKTTASTRKVSLAPQANLTEL	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.40	-	-
S	813	TELDIYSRRLSQETGLEISEE	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.29	-	-

Substrate:

Chorionic gonadotrophin beta subunit (choriogonatropin beta chain precursor (from PhosphoBase))

Seq-ID:

P01233 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-24926 GLHA_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
hormone activity	extracellular region, soluble fraction	apoptosis, signal transduction, cell-cell signaling, female gamete generation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	86	VCNYRDVRFESIRLPGCPRGV	PKA_group	6196363	LTP	0.16		-	GHB	0.16	1HCN	57.38%
S	116	LSCQCALCRRSTTDCGGPKDH	PKA_group	6196363	LTP	0.22	MOD_PKA_1	-	GHB	0.11	1HCN	78.69%
T	117	SCQCALCRRSTTDCGGPKDHP	PKA_group	6196363	LTP	0.84	MOD_PKA_1	-	GHB	0.12	1HCN	59.59%

Substrate:

Common beta c subunit (Cytokine recpetor common beta chain)

Seq-ID:

P32927 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cytokine receptor activity	granulocyte macrophage colony-stimulating factor receptor complex	respiratory gaseous exchange

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	601	GPYLGPPHSRSLPDILGQPEP	PKA_group	10949031	LTP	1.00		YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.90	-	medium

Substrate:

Connexin 32 (Intercellular channel)

Seq-ID:

P08033 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
gap junction channel activity	connexon complex, integral to membrane, endoplasmic reticulum	protein oligomerization, cell communication, purine ribonucleotide transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	233	RRSNPPSRKGSGFGHRLSPEY	PKA_group	2170122	LTP	0.61	MOD_PKA_1	-	-	0.52	-	medium

Substrate:

Connexin 32 (Intercellular channel)

Seq-ID:

P08034 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
gap junction channel activity	connexon complex, integral to membrane, endoplasmic reticulum membrane	nervous system development, cell-cell signaling

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	233	RRSNPPSRKGSGFGHRLSPEY	PKA_group	8390988	LTP	0.49	MOD_PKA_1	-	-	0.52	-	low

Substrate:

CPI-17 (Inhibitor of PPP1CA)

Seq-ID:

Q96A00 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-16604 KC1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity, protein binding	cytoplasm	regulation of phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	38	GGLQKRHARVTVKYDRRELQR	PKA_group	15003508	LTP	1.00	MOD_PKA_2	-	PP1_inhibitor	0.51	-	medium

Substrate:

CTP synthase (Enzyme: Ligase)

Seq-ID:

P17812 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3296359 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP binding, CTP synthase activity, protein binding		CTP biosynthetic process, response to drug, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	455	GGTMRLGKRRTLFQTKNSVMR	PKA_group	17189248	LTP	1.00	MOD_PKA_1	-	GATase	0.37	-	medium

Substrate:

Cullin 5 (Ubiquitin proteasome system protein)

Seq-ID:

Q93034 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-61623 SMAD2_HUMAN
MINT-7277713 ELOA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, calcium channel activity, ubiquitin protein ligase binding	cytosol, cullin-RING ubiquitin ligase complex	negative regulation of cell proliferation, cell cycle arrest, G1/S transition of mitotic cell cycle, induction of apoptosis by intracellular signals, interspecies interaction between organisms, ubiquitin-dependent protein catabolic process, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	730	IQIMKMRKKISNAQLQTELVE	PKA_group	10898738	LTP	0.31	MOD_PKA_1	-	Cullin_Nedd8	0.16	3DPL	31.97%

Substrate:

Cut like 1 (Transcription regulatory protein)

Seq-ID:

P39880 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13924   RB_HUMAN
MINT-64663   BIN1_HUMAN
MINT-64665   RECQ5_HUMAN
MINT-64666   RNZ2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity	nucleus	transcription, negative regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1215	EKKAYMKRRHSSVSDSQPCEP	PKA_group	16574653	LTP	1.00	MOD_PKA_1	-	-	0.68	-	medium

Substrate:

Cyclic-AMP-dependent transcription factor ATF-2 (Transcription factor)

Seq-ID:

P15336 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1788416   JUNB_HUMAN
MINT-6628041   JUN_HUMAN
MINT-6628046   CITE1_HUMAN
MINT-6699865   I2BP1_HUMAN
MINT-7555703   HDAC4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, protein dimerization activity, RNA polymerase II transcription factor activity, transcription coactivator activity, zinc ion binding, sequence-specific DNA binding transcription factor activity	nucleoplasm	transcription, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	44	TLKFGPARNDSVIVADQTPTP	PKA_group	1661585	LTP	0.00		-	-	0.62	-	-
S	44	TLKFGPARNDSVIVADQTPTP	PKA_group	1661585	LTP	0.00		-	-	0.62	-	-

Substrate:

Cyclin D1 (Cyclin D1)

Seq-ID:

P24385 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50433   CDK4_HUMAN
MINT-50434   CDK6_HUMAN
MINT-50435   MCM10_HUMAN
MINT-50437   CDN1A_HUMAN
MINT-7033534   CDK4_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding	cytosol, cyclin-dependent protein kinase holoenzyme complex, nucleoplasm	positive regulation of protein amino acid phosphorylation, cell division, response to UV-A, mitotic cell cycle G1/S DNA damage checkpoint, G1/S transition of mitotic cell cycle, response to drug, positive regulation of cyclin-dependent protein kinase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	90	LAMNYLDRFLSLEPVKKSRLQ	PKA_group	8058338	LTP	1.00	-	CYCLIN	0.08	2W96	14.75%
S	197	ALCATDVKFISNPPSMVAAGS	PKA_group	8058338	LTP	0.06	-	Cyclin_C	0.16	2W96	57.38%
S	234	LSYYRLTRFLSRVIKCDPDCL	PKA_group	8058338	LTP	0.15	-	Cyclin_C	0.05	2W96	4.10%

Substrate:

Cytochrome P450 2B1 (cytochrome P450 IIB1 (P450-B) (from PhosphoBase))

Seq-ID:

P00176 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
heme binding, electron carrier activity, aromatase activity, steroid hydroxylase activity	microsome, endoplasmic reticulum membrane	response to sulfur dioxide, oxidation reduction, drug metabolic process, response to organic cyclic substance, response to drug, response to calcium ion, response to insulin stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	128	GERWKALRRFSLATMRDFGMG	PKA_group	2583091	LTP	0.97	MOD_PKA_1	-	p450	0.10	-	medium

Substrate:

Cytochrome P450 2B2 (cytochrome P450 IIB2 (P450E) (from PhosphoBase))

Seq-ID:

P04167 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
heme binding, electron carrier activity, aromatase activity, steroid hydroxylase activity	microsome, endoplasmic reticulum membrane	oxidation reduction, drug metabolic process, response to organic cyclic substance, aging, response to calcium ion, nicotine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	128	GERWKALRRFSLATMRDFGMG	PKA_group	2583091	LTP	0.97	MOD_PKA_1	-	p450	0.10	-	low

Substrate:

DARPP-32 (Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32))

Seq-ID:

P07516 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity	cytoplasm	signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	34	QVEMIRRRRPTPAMLFRLSEH	PKA_group	3511054	LTP	1.00		-	DARPP-32	0.73	-	high

Substrate:

Dematin (Structural protein)

Seq-ID:

Q08495 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-64072 SMD2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
actin binding	cytoplasm, actin cytoskeleton	actin filament capping, actin filament bundle assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	403	WKRNELKKKASLF	PKA_group	7615546	LTP	0.00		-	VHP	0.24	-	-

Substrate:

Desmin (desmin (from PhosphoBase))

Seq-ID:

P02542 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity	intermediate filament, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	29	GGTSPVFPRASFGSRGSGSSV	PKA_group	3359992	LTP	0.69	MOD_PKA_2	-	Filament_head	0.50	-	low
S	35	FPRASFGSRGSGSSVTSRVYQ	PKA_group	3359992	LTP	0.83	MOD_PKA_2	-	Filament_head	0.41	-	low
S	50	TSRVYQVSRTSAVPTLSTFRT	PKA_group	3359992	LTP	0.97	MOD_PKA_2	-	Filament_head	0.39	-	low

Substrate:

Desmoplakin (Cytoskeletal protein)

Seq-ID:

P15924 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48119   IKKE_HUMAN
MINT-48557   NFKB1_HUMAN
MINT-49027   RELB_HUMAN
MINT-1792815   PKP4_HUMAN
MINT-3318871   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, protein binding, bridging	desmosome, cornified envelope	keratinocyte differentiation, peptide cross-linking

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2849	SGSRSGSRRGSFDATGNSSYS	PKA_group	7525582	LTP	1.00	MOD_PKA_1	-	-	0.58	-	-

Substrate:

DPDE4 (Enzyme: Phosphodiesterase)

Seq-ID:

Q07343 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, 3`,5`-cyclic-AMP phosphodiesterase activity	cytosol, insoluble fraction, soluble fraction	signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	133	TFPGHSQRRESFLYRSDSDYD	PKA_group	12441002	LTP	1.00	MOD_PKA_1	-	-	0.52	-	low

Substrate:

Drp1 (GTPase)

Seq-ID:

O00429 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, protein binding	cis-Golgi network, cytosol, mitochondrial outer membrane, endoplasmic reticulum, endomembrane system	mitochondrial fragmentation involved in apoptosis, mitochondrial membrane organization, cell communication, multicellular organismal development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	637	DVPVPVARKLSAREQRDCEVI	PKA_group	17553808	LTP	0.71	MOD_PKA_1	-	-	0.40	-	medium

Substrate:

Drp1 (GTPase)

Seq-ID:

O35303 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, protein binding	microsome, mitochondrion, cytosol, peroxisome, membrane, endomembrane system

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	656	DVPVPVARKLSAREQRDCEVI	PKA_group	17721437	LTP	0.69	MOD_PKA_1	-	-	0.40	-	low

Substrate:

E3 ubiquitin-protein ligase Nedd-4-like protein (Ubiquitin-protein ligase activity)

Seq-ID:

Q96PU5 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-61615 SMAD2_HUMAN
MINT-63860 GDIR1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sodium channel regulator activity, protein binding, ubiquitin-protein ligase activity	cytoplasm	positive regulation of endocytosis, water homeostasis, excretion, sodium ion transport, interspecies interaction between organisms, cellular sodium ion homeostasis, regulation of protein catabolic process, response to metal ion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	342	REPSSRLRSCSVTDAVAEQGH	PKA_group	15328345	LTP	0.96		-	-	0.73	-	medium
T	367	SAPAGRARSSTVTGGEEPTPS	PKA_group	15328345	LTP	0.04	MOD_PKA_2	-	-	0.90	-	medium
S	448	EPQIRRPRSLSSPTVTLSAPL	PKA_group	15328345	LTP	1.00		-	-	0.74	-	medium

Substrate:

eIF-2-beta (eukaryotic translation initation factor 2 beta subunit (from PhosphoBase))

Seq-ID:

P41035 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
translation initiation factor activity, metal ion binding

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	218	QVVRVGTKKTSFVNFTDICKL	PKA_group	8024572	LTP	0.21	MOD_PKA_1	-	eIF2B_5	0.18	-	medium

Substrate:

Erythrocyte band 7 integral membrane protein (erythrocyte band 7 integral membrane protein (stomatin) (from PhosphoBase))

Seq-ID:

P27105 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	integral to plasma membrane, melanosome, cytoskeleton, membrane raft	protein homooligomerization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	10	MAEKRHTRDSEAQRLPDSFK	PKA_group	8373790	LTP	0.14	MOD_PKA_1	-	-	0.49	-	low

Substrate:

Erythrocyte membrane protein band 4.2 (erythrocyte membrane protein band 4.2 (P4.2) (pallidin) (from PhosphoBase))

Seq-ID:

P16452 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, ATP binding, protein-glutamine gamma-glutamyltransferase activity, protein binding	plasma membrane, cytoplasm, cytoskeleton	erythrocyte maturation, regulation of cell shape, peptide cross-linking

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	248	EGALLNKRRGSVPILRQWLTG	PKA_group	8499466	LTP	1.00	MOD_PKA_1	-	Transglut_core	0.21	-	medium

Substrate:

Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )

Seq-ID:

P03372 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13786   BRCA1_HUMAN
MINT-50646   STA5A_HUMAN
MINT-50709   M3K1_HUMAN
MINT-5222241   NCOA1_HUMAN
MINT-6169667   EGFR_HUMAN
MINT-6614126   SMCA4_HUMAN
MINT-6614301   CHD3_HUMAN
MINT-6614361   MTA1_HUMAN
MINT-6614421   MTA2_HUMAN
MINT-6761899   PTN1_HUMAN
MINT-6761906   PTN6_HUMAN
MINT-7013584   PA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
beta-catenin binding, nitric-oxide synthase regulator activity, estrogen response element binding, steroid binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, estrogen receptor activity	chromatin remodeling complex	response to estradiol stimulus, transcription, DNA-dependent, regulation of transcription, DNA-dependent, positive regulation of retinoic acid receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	236	QCTIDKNRRKSCQACRLRKCY	PKA_group	9891036	LTP	1.00	MOD_PKA_1	-	ZnF_C4	0.22	1HCQ	73.77%

Substrate:

ETV5 (transcription factor activity)

Seq-ID:

P41161 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
promoter binding, sequence-specific DNA binding transcription factor activity	nucleus	cellular response to oxidative stress, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	367	REGPPYQRRGSLQLWQFLVTL	PKA_group	11682477	LTP	1.00	MOD_PKA_1	-	ETS	0.21	-	low

Substrate:

FGF2 (protein binding)

Seq-ID:

P09038 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
fibroblast growth factor receptor binding, heparin binding, growth factor activity	extracellular space	branching involved in ureteric bud morphogenesis, positive regulation of cell fate specification, positive regulation of ERK1 and ERK2 cascade, positive regulation of blood vessel endothelial cell migration, positive regulation of cardiac muscle cell proliferation, negative regulation of cell death, negative regulation of blood vessel endothelial cell migration, activation of MAPK activity, chondroblast differentiation, chemotaxis, cell migration involved in sprouting angiogenesis, Ras protein signal transduction, positive regulation of cell division, fibroblast growth factor receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	121	NYNTYRSRKYTSWYVALKRTG	PKA_group	2541433	LTP	-	MOD_PKA_1	-	FGF	0.20	1BFG	53.42%

Substrate:

Fibrinogen alpha chain (fibrinogen (from PhosphoBase))

Seq-ID:

P02671 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-62797 BAT2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
eukaryotic cell surface binding, protein binding, bridging, receptor binding	external side of plasma membrane, fibrinogen complex, platelet alpha granule lumen	signal transduction, protein polymerization, response to calcium ion, platelet activation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	460	TSGSTTTTRRSCSKTVTKTVI	PKA_group	6255944	LTP	1.00	MOD_PKA_2	-	-	0.65	-	medium

Substrate:

Fructose-1,6-bisphosphatase (fructose-1,6-bisphosphatase (from PhosphoBase))

Seq-ID:

P09201 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
fructose 1,6-bisphosphate 1-phosphatase activity, identical protein binding, metal ion binding	cytosol	gluconeogenesis, oxygen and reactive oxygen species metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	12	PTLVNGPRRDSTEGFDTDIIT	PKA_group	3005313	LTP	0.17	MOD_PKA_1	-	-	0.40	-	medium

Substrate:

Fructose-1,6-bisphosphatase (fructose-1,6-bisphosphatase (from PhosphoBase))

Seq-ID:

P19112 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
fructose 1,6-bisphosphate 1-phosphatase activity, metal ion binding, monosaccharide binding	cytosol, soluble fraction	gluconeogenesis, fructose 6-phosphate metabolic process, cellular response to insulin stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	339	LEIYNKDKAKSRPSLPLPQSR	PKA_group	2824503	LTP	0.14	MOD_PKA_2	-	-	0.48	-	medium
S	342	YNKDKAKSRPSLPLPQSRARE	PKA_group	6274412	LTP	0.48	MOD_PKA_2	-	-	0.61	-	medium
S	357	QSRARESPVHSICDELF	PKA_group	2824503	LTP	-		-	-	0.36	-	medium

Substrate:

G alpha 13 (G protein)

Seq-ID:

Q14344 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, signal transducer activity	melanosome	cellular component movement

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	203	QQDILLARRPTKGIHEYDFEI	PKA_group	12399457	LTP	1.00	MOD_PKA_1	-	G_alpha	0.20	-	low

Substrate:

GABA(A) receptor B1 (gamma-aminobutyric-acid receptor beta-1 subunit precursor (from PhosphoBase))

Seq-ID:

P18505 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity	cell junction, integral to plasma membrane, chloride channel complex, postsynaptic membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	434	PSKGRIRRRASQLKVKIPDLT	PKA_group	1321150	LTP	0.79	MOD_PKA_1	-	Neur_chan_memb	0.42	-	medium

Substrate:

GFAP (glial fibrillary acidic protein, astrocyte (GFAP) (from PhosphoBase))

Seq-ID:

Q28115 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	intermediate filament, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	7	MERRRVTSATRRSYVSS	PKA_group	2155236	LTP	0.11	MOD_PKA_1	-	Filament_head	0.53	-	medium
S	8	MERRRVTSATRRSYVSSS	PKA_group	2155236	LTP	0.95	MOD_PKA_1	-	Filament_head	0.53	-	medium
S	13	RRRVTSATRRSYVSSSEMVVG	PKA_group	2155236	LTP	0.72	MOD_PKA_2	-	Filament_head	0.47	-	medium
S	34	GRRLGPGTRLSLARMPPPLPA	PKA_group	2155236	LTP	1.00	MOD_PKA_2	-	Filament_head	0.58	-	medium

Substrate:

GFPT2 (glutamine-fructose-6-phosphate transaminase...)

Seq-ID:

O94808 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sugar binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity	cytoplasm	carbohydrate biosynthetic process, fructose 6-phosphate metabolic process, energy reserve metabolic process, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	202	PGEAVATRRGSPLLIGVRSKY	PKA_group	15133036	LTP	0.99		-	GATase_2	0.24	-	medium

Substrate:

Glucosamine--fructose-6-phosphate aminotransferase (Enzyme: Aminotransferase)

Seq-ID:

Q06210 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sugar binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity	cytoplasm	carbohydrate biosynthetic process, fructose 6-phosphate metabolic process, energy reserve metabolic process, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	205	PGQAVGTRRGSPLLIGVRSEH	PKA_group	10806197	LTP	0.99	-	GATase_2	0.38	-	medium
S	205	PGQAVGTRRGSPLLIGVRSEH	PKA_group	9836513	LTP	0.99	-	GATase_2	0.38	-	medium
S	235	LYRTARTQIGSKFTRWGSQGE	PKA_group	10806197	LTP	-	-	-	0.38	-	medium
S	235	LYRTARTQIGSKFTRWGSQGE	PKA_group	9836513	LTP	-	-	-	0.38	-	medium

Substrate:

GluR-1 (Extracellular ligand gated channel)

Seq-ID:

P42261 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-18147 KAPCA_HUMAN
MINT-49811 CXCR2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
kainate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity	endocytic vesicle membrane, cell junction, endoplasmic reticulum membrane, postsynaptic membrane	synaptic transmission

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	863	AIRTSTLPRNSGAGASSGGSG	PKA_group	8663994	LTP	0.42	MOD_PKA_2	-	-	0.60	-	low

Substrate:

GluR-4 (Extracellular ligand gated channel)

Seq-ID:

P48058 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-17826 KCC2A_HUMAN
MINT-49874 KAPCA_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
extracellular-glutamate-gated ion channel activity	endocytic vesicle membrane, cell junction, postsynaptic membrane	glutamate signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	862	SEAIRNKARLSITGSVGENGR	PKA_group	10366608	LTP	0.94	MOD_PKA_2	-	-	0.30	-	low

Substrate:

GluR-6 (glutamate receptor 6 precursor (GluR-6) (glutamate receptor, (from PhosphoBase))

Seq-ID:

Q13002 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
kainate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity	cell junction, postsynaptic membrane	positive regulation of synaptic transmission, neuron apoptosis, regulation of short-term neuronal synaptic plasticity, glutamate signaling pathway, induction of programmed cell death in response to chemical stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	697	DGATMTFFKKSKISTYDKMWA	PKA_group	8382377	LTP	0.98		-	PBPe	0.09	1S50	16.39%
S	715	MWAFMSSRRQSVLVKSNEEGI	PKA_group	8382377	LTP	0.82	MOD_PKA_1	-	PBPe	0.22	1S50	45.08%

Substrate:

Glycogenin-1 (glycogenin (from PhosphoBase))

Seq-ID:

P13280 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
glycogenin glucosyltransferase activity		glycogen biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	44	RLAVLTTPQVSDTMRKALEIV	PKA_group	3151442	LTP	0.97		-	Glyco_transf_8	0.22	1LL2	34.43%

Substrate:

GMF-beta (Glia maturation factor)

Seq-ID:

P60983 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
enzyme activator activity, protein kinase inhibitor activity, growth factor activity, actin binding, signal transducer activity	intracellular	nervous system development, protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	27	KLRKFRFRKETNNAAIIMKID	PKA_group	9030586	LTP	0.31	MOD_PKA_1	-	ADF	0.19	-	medium
S	83	YKYQHDDGRVSYPLCFIFSSP	PKA_group	9030586	LTP	0.96	MOD_PKA_2	-	ADF	0.09	-	medium

Substrate:

GRK7 (ser/thr kinase)

Seq-ID:

Q8WTQ7 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
G-protein coupled receptor kinase activity, ATP binding, signal transducer activity	membrane	protein amino acid phosphorylation, visual perception, response to stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	23	NTAYLQARKPSDCDSKELQRR	PKA_group	15946941	LTP	0.04	MOD_PKA_1	-	-	0.43	-	medium
S	36	DSKELQRRRRSLALPGLQGCA	PKA_group	15946941	LTP	0.19	MOD_PKA_1	-	-	0.38	-	medium

Substrate:

GSK-3 alpha (Glycogen synthase kinase-3 alpha)

Seq-ID:

P49840 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-4544606 AXN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, tau-protein kinase activity, ATP binding, protein kinase A catalytic subunit binding	beta-catenin destruction complex, cytosol	positive regulation of protein catabolic process, protein amino acid phosphorylation, negative regulation of insulin receptor signaling pathway, negative regulation of transferase activity, negative regulation of glucose import, insulin receptor signaling pathway, negative regulation of UDP-glucose catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	PGGSGRARTSSFAEPGGGGGG	PKA_group	11035810	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium

Substrate:

GSK-3 beta (Glycogen synthase kinase-3 beta)

Seq-ID:

P49841 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-65985   DBPA_HUMAN
MINT-65986   YBOX1_HUMAN
MINT-2837737   PSN1_HUMAN
MINT-3974216   TAU_HUMAN
MINT-4049759   PCM1_HUMAN
MINT-4049773   NIN_HUMAN
MINT-4508051   CTNB1_HUMAN
MINT-4508259   AXN1_HUMAN
MINT-4793253   P53_HUMAN
MINT-6761890   PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, tau-protein kinase activity, p53 binding, beta-catenin binding, ATP binding, protein kinase A catalytic subunit binding, NF-kappaB binding	Axin-APC-beta-catenin-GSK3B complex, beta-catenin destruction complex, cytosol, nucleus	positive regulation of protein catabolic process, hippocampus development, negative regulation of apoptosis, positive regulation of protein export from nucleus, positive regulation of Rac GTPase activity, positive regulation of protein complex assembly, peptidyl-serine phosphorylation, glycogen metabolic process, superior temporal gyrus development, canonical Wnt receptor signaling pathway, ER overload response, negative regulation of protein binding, positive regulation of cell-matrix adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	9	MSGRPRTTSFAESCKPVQQ	PKA_group	11035810	LTP	0.60	MOD_PKA_2	-	-	0.61	-	-

Substrate:

HAND1 (Transcription factor)

Seq-ID:

O96004 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, protein homodimerization activity, bHLH transcription factor binding, transcription coactivator activity	cytoplasm, nucleolus, nucleoplasm	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, cardiac left ventricle formation, positive regulation of gene-specific transcription from RNA polymerase II promoter, angiogenesis, cardiac septum morphogenesis, cardiac right ventricle formation, heart looping, ventricular cardiac muscle tissue morphogenesis, trophectodermal cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	98	LGGRLGRRKGSGPKKERRRTE	PKA_group	14636580	LTP	0.22	MOD_PKA_1	-	HLH	0.85	-	medium
T	107	GSGPKKERRRTESINSAFAEL	PKA_group	14636580	LTP	1.00	MOD_PKA_1	-	HLH	0.70	-	medium
S	109	GPKKERRRTESINSAFAELRE	PKA_group	14636580	LTP	1.00	MOD_PKA_1	-	HLH	0.63	-	medium

Substrate:

HDAC8 (histone deacetylase activity, transcription factor binding)

Seq-ID:

Q9BY41 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-5207405 P53_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, histone deacetylase activity, transcription factor binding	histone deacetylase complex, cytoplasm, nuclear chromosome	transcription, histone deacetylation, chromatin assembly or disassembly, negative regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	39	DSLAKIPKRASMVHSLIEAYA	PKA_group	14701748	LTP	0.20	MOD_PKA_1	-	Hist_deacetyl	0.15	3EW8	22.95%

Substrate:

Histone H1.1

Seq-ID:

P02253 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	nucleosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	35	KKPAGARRKASGPPVSELITK	PKA_group	1137958	LTP	1.00	MOD_PKA_1	-	H15	0.64	-	medium

Substrate:

Histone H2A.c/d/i/n/p (histone H2A.1 (from PhosphoBase))

Seq-ID:

P0C0S9 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	nucleosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	20	KARAKAKTRSSRAGLQFPVGR	PKA_group	1137958	LTP	-	MOD_PKA_2	-	H2A	0.50	2CV5	59.02%

Substrate:

Histone H2B.a/g/h/k/l (histone H2B (from PhosphoBase))

Seq-ID:

P62807 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding, protein binding	nucleus, nucleosome	defense response to bacterium, nucleosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	15	AKSAPAPKKGSKKAVTKAQKK	PKA_group	1137958	LTP	0.00	MOD_PKA_1	-	-	0.79	-	-
S	33	QKKDGKKRKRSRKESYSVYVY	PKA_group	192223	LTP	0.30	MOD_PKA_1	-	H2B	0.53	2CV5	98.36%
S	37	GKKRKRSRKESYSVYVYKVLK	PKA_group	192223	LTP	1.00	MOD_PKA_1	-	H2B	0.42	2CV5	47.54%

Substrate:

HLA-A1 (MHC complex protein)

Seq-ID:

P30443 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
MHC class I receptor activity	MHC class I protein complex, integral to plasma membrane	immune response, interspecies interaction between organisms, antigen processing and presentation of peptide antigen via MHC class I

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	336	VVAAVMWRRKSSDRKGGSYTQ	PKA_group	6333425	LTP	0.95	MOD_PKA_1	-	MHC_I_C	0.38	-	medium
S	337	VAAVMWRRKSSDRKGGSYTQA	PKA_group	6333425	LTP	0.95	MOD_PKA_1	-	MHC_I_C	0.41	-	medium
S	343	RRKSSDRKGGSYTQAASSDSA	PKA_group	6333425	LTP	0.89		-	MHC_I_C	0.61	-	medium

Substrate:

HMG14 (Transcription regulatory protein)

Seq-ID:

P02316 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	chromatin, nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	MPKRKVSSAEGAAKEEPK	PKA_group	6279643	LTP	0.00	MOD_PKA_1	-	HMG17	0.91	-	medium

Substrate:

HMG14 (Transcription regulatory protein)

Seq-ID:

P05114 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
positive transcription elongation factor activity, DNA binding, RNA polymerase II transcription factor activity	cytoplasm, chromatin, nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	GAAKEEPKRRSARLSAKPPAK	PKA_group	11438671	LTP	1.00	MOD_PKA_1	-	HMG17	0.91	-	medium
S	25	EEPKRRSARLSAKPPAKVEAK	PKA_group	11438671	LTP	1.00	MOD_PKA_2	-	HMG17	0.91	-	medium

Substrate:

hnRPA1 (RNA binding protein)

Seq-ID:

P09651 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48852   M3K14_HUMAN
MINT-62794   BAT2_HUMAN
MINT-3296922   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nucleotide binding, single-stranded RNA binding, single-stranded DNA binding, protein binding	spliceosomal complex, cytoplasm, nucleolus, nucleoplasm, heterogeneous nuclear ribonucleoprotein complex	mRNA transport, nuclear import, interspecies interaction between organisms, RNA export from nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	199	ASSSQRGRSGSGNFGGGRGGG	PKA_group	8451194	LTP	0.27		-	-	0.70	-	-

Substrate:

hnRPD (Ribonucleoprotein)

Seq-ID:

Q14103 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nucleotide binding, transcription activator activity, telomeric DNA binding, RNA binding, protein binding	chromosome, heterogeneous nuclear ribonucleoprotein complex	transcription, regulation of transcription, DNA-dependent, RNA catabolic process, RNA splicing

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	87	EGHSNSSPRHSEAATAQREEW	PKA_group	12819195	LTP	-	MOD_PKA_2	-	-	0.85	-	-

Substrate:

HRH1 (G-protein coupled receptor activity, histamine receptor activity)

Seq-ID:

P35367 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
histamine receptor activity	integral to plasma membrane	inflammatory response, activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	398	KFTWKRLRSHSRQYVSGLHMN	PKA_group	15107581	LTP	1.00		-	7tm_1	0.19	-	medium

Substrate:

HSP27 (heat shock 27 kD protein (HSP 27) (from PhosphoBase))

Seq-ID:

P14602 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	plasma membrane, insoluble fraction, soluble fraction, nucleus, Z disc	response to heat

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	15	RVPFSLLRSPSWEPFRDWYPA	PKA_group	1332886	LTP	1.00		-	-	0.14	-	medium
S	86	AFSRALNRQLSSGVSEIRQTA	PKA_group	1332886	LTP	0.31		-	-	0.41	-	medium

Substrate:

Inositol 1,4,5-trisphosphate receptor type 1 (inositol 1,4,5-trisphosphate-binding protein type 1 receptor (from PhosphoBase))

Seq-ID:

P29994 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, protein binding	plasma membrane, secretory granule membrane, integral to membrane, endoplasmic reticulum membrane, membrane raft, postsynaptic density	elevation of cytosolic calcium ion concentration

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1756	GNIRPSGRRESLTSFGNGPLS	PKA_group	7935353	LTP	0.50	MOD_PKA_1	-	-	0.64	-	medium

Substrate:

Integrin alpha 4 (Cell surface receptor)

Seq-ID:

P13612 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, identical protein binding	integrin complex	B cell differentiation, integrin-mediated signaling pathway, leukocyte cell-cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1027	SILQEENRRDSWSYINSKSND	PKA_group	11533025	LTP	0.05	MOD_PKA_1	-	-	0.36	-	medium

Substrate:

IPP1 (protein phosphatase inhibitor 1 (IPP-1) (from PhosphoBase))

Seq-ID:

P01099 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity		signal transduction, glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	35	AAEQIRRRRPTPATLVLTSDQ	PKA_group	193727	LTP	1.00		-	DARPP-32	0.89	-	medium

Substrate:

L-plastin (Calcium binding protein)

Seq-ID:

P13796 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding	cell junction, cytosol, ruffle membrane	T cell activation involved in immune response, regulation of intracellular protein transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	5	MARGSVSDEEMMELR	PKA_group	10446213	LTP	0.28	MOD_PKA_2	-	-	0.45	-	medium
S	7	MARGSVSDEEMMELREA	PKA_group	10446213	LTP	0.81	MOD_PKA_2	-	-	0.41	-	medium

Substrate:

Lamin Dm0 (lamin Dm0 (from PhosphoBase))

Seq-ID:

P08928 [Drosophila melanogaster]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-42096 IMA_DROME
MINT-42822 OTE_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, receptor binding	lipid particle, microtubule associated complex, lamin filament, nuclear envelope	gonad morphogenesis, terminal branching, open tracheal system, central nervous system development, compound eye morphogenesis, nuclear migration, chromatin silencing, chitin-based cuticle development, mitotic nuclear envelope reassembly, digestive tract morphogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	50	ASSPLSPTRHSRVAEKVELQN	PKA_group	9013881	LTP	1.00	MOD_PKA_2	-	-	0.80	-	medium

Substrate:

LASP1 (Cytoskeletal protein)

Seq-ID:

Q14847 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-66300 TRP13_HUMAN
MINT-66313 PLS1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ion transmembrane transporter activity, SH3/SH2 adaptor activity, zinc ion binding, actin binding	focal adhesion, cortical actin cytoskeleton

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	146	GEGMEPERRDSQDGSSYRRPL	PKA_group	12571245	LTP	0.95	MOD_PKA_1	-	-	0.90	-	low

Substrate:

Lipase hormone sensitive (Enzyme: Lipase)

Seq-ID:

P15304 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7211789 KAPCA_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
rRNA primary transcript binding, acylglycerol lipase activity, RNA polymerase I transcription termination factor activity, hormone-sensitive lipase activity, protein binding	lipid particle, mitochondrion, caveola, cytosol, extracellular space, nucleus	triglyceride catabolic process, response to drug, female pregnancy, cholesterol metabolic process, transcription initiation from RNA polymerase I promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	863	SGRLTESMRRSVSEAALAQPE	PKA_group	15294048	LTP	0.17	MOD_PKA_2	-	Abhydrolase_3	0.63	-	medium
S	959	AFPDGFHPRRSSQGVLHMPLY	PKA_group	15294048	LTP	0.13	MOD_PKA_1	-	Abhydrolase_3	0.44	-	medium
S	960	FPDGFHPRRSSQGVLHMPLYS	PKA_group	15294048	LTP	0.32	MOD_PKA_1	-	Abhydrolase_3	0.42	-	medium

Substrate:

Lipase hormone sensitive (Enzyme: Lipase)

Seq-ID:

P16386 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
rRNA primary transcript binding, RNA polymerase I transcription termination factor activity, hormone-sensitive lipase activity, lipase activity	mitochondrion, caveola, cytosol, nucleus	lipid catabolic process, cholesterol metabolic process, transcription initiation from RNA polymerase I promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	KTEPMRRSVSEAALTQPE	PKA_group	3345839	LTP	0.79	MOD_PKA_2	-	-	0.92	-	medium

Substrate:

Lipase hormone sensitive (Enzyme: Lipase)

Seq-ID:

Q05469 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
hormone-sensitive lipase activity, protein binding	caveola, cytosol	protein amino acid phosphorylation, cholesterol metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	853	SEPIAEPMRRSVSEAALAQPQ	PKA_group	3345839	LTP	0.17	MOD_PKA_2	-	Abhydrolase_3	0.69	-	medium
S	853	SEPIAEPMRRSVSEAALAQPQ	PKA_group	16188906	LTP	0.17	MOD_PKA_2	-	Abhydrolase_3	0.69	-	medium
S	855	PIAEPMRRSVSEAALAQPQGP	PKA_group	15033481	LTP	0.43	MOD_PKA_2	-	Abhydrolase_3	0.72	-	medium
S	950	AFPEGFHPRRSSQGATQMPLY	PKA_group	9417067	LTP	0.13	MOD_PKA_1	-	Abhydrolase_3	0.62	-	medium
S	951	FPEGFHPRRSSQGATQMPLYS	PKA_group	9417067	LTP	0.32	MOD_PKA_1	-	Abhydrolase_3	0.60	-	medium

Substrate:

Lipocortin I (annexinI) ( Ca++, phospholipids and actin-binding protein)

Seq-ID:

P04083 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51101 EGFR_HUMAN
MINT-3297886 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium-dependent phospholipid binding, calcium ion binding, phospholipase A2 inhibitor activity, protein binding, bridging, structural molecule activity, receptor binding	extracellular region, cilium, cytoplasm, basolateral plasma membrane, cornified envelope, nucleus	positive regulation of vesicle fusion, lipid metabolic process, keratinocyte differentiation, anti-apoptosis, cellular component movement, signal transduction, inflammatory response, cell surface receptor linked signaling pathway, peptide cross-linking

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	216	LYEAGERRKGTDVNVFNTILT	PKA_group	2457390	LTP	1.00	MOD_PKA_1	-	ANX	0.31	1AIN	0.0%

Substrate:

Lysozyme C (egg white lysozyme C (from PhosphoBase))

Seq-ID:

P00698 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
lysozyme activity	extracellular space	defense response to bacterium, cell wall macromolecule catabolic process, cytolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	42	RHGLDNYRGYSLGNWVCAAKF	PKA_group	169238	LTP	1.00		-	LYZ1	0.05	1V7S	39.34%
S	68	TQATNRNTDGSTDYGILQINS	PKA_group	169238	LTP	1.00	MOD_PKA_2	-	LYZ1	0.28	1V7S	0.00%

Substrate:

MBP (myelin basic protein (MBP) (from PhosphoBase))

Seq-ID:

P02687 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6613181 MK01_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of myelin sheath, protein binding	plasma membrane, myelin sheath

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	7	AAQKRPSQRSKYLASAS	PKA_group	2413024	LTP	0.42	MOD_PKA_1	-	-	0.80	-	low
S	10	AAQKRPSQRSKYLASASTMD	PKA_group	2413024	LTP	0.12	MOD_PKA_1	-	-	0.82	-	low
T	33	RHGFLPRHRDTGILDSLGRFF	PKA_group	4833512	LTP	0.17	MOD_PKA_2	-	Myelin_MBP	0.52	-	low
S	54	GSDRGAPKRGSGKDGHHAART	PKA_group	2413024	LTP	0.45	MOD_PKA_1	-	Myelin_MBP	0.87	-	low
S	109	PPSQGKGRGLSLSRFSWGAEG	PKA_group	4833512	LTP	1.00		-	Myelin_MBP	0.71	-	low
S	131	KPGFGYGGRASDYKSAHKGLK	PKA_group	2413024	LTP	0.87	MOD_PKA_2	-	Myelin_MBP	0.63	-	low
S	160	SKIFKLGGRDSRSGSPMARR	PKA_group	2413024	LTP	1.00	MOD_PKA_2	-	Myelin_MBP	0.71	-	low

Substrate:

Melanocortin 4 receptor (G protein coupled receptor)

Seq-ID:

P32245 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ubiquitin protein ligase binding, neuropeptide binding, melanocyte-stimulating hormone receptor activity	plasma membrane, integral to membrane	positive regulation of cAMP biosynthetic process, positive regulation of bone resorption, feeding behavior, G-protein signaling, coupled to cAMP nucleotide second messenger

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	312	YALRSQELRKTFKEIICCYPL	PKA_group	12639913	LTP	1.00	MOD_PKA_2	-	7TM_GPCR_Srsx	0.01	-	low
S	329	CYPLGGLCDLSSRY	PKA_group	12639913	LTP	0.20		-	-	0.01	-	low
S	330	YPLGGLCDLSSRY	PKA_group	12639913	LTP	0.00		-	-	0.01	-	low

Substrate:

Merlin (Probably acts as a ,15, stabilizing protein)

Seq-ID:

P35240 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cytoskeletal protein binding	early endosome, cytoskeleton, nucleolus, ruffle membrane, extrinsic to membrane, perinuclear region of cytoplasm, filopodium membrane	negative regulation of DNA replication, actin cytoskeleton organization, negative regulation of tyrosine phosphorylation of Stat5 protein, positive regulation of stress fiber assembly, negative regulation of cell proliferation, regulation of hippo signaling cascade, negative regulation of cell-matrix adhesion, Schwann cell proliferation, negative regulation of cell-cell adhesion, negative regulation of cell migration, negative regulation of tyrosine phosphorylation of Stat3 protein

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	518	DFKDTDMKRLSMEIEKEKVEY	PKA_group	14981079	LTP	1.00	MOD_PKA_1	-	COIL	0.46	-	medium

Substrate:

MHC class II transactivator (Transcription regulatory protein)

Seq-ID:

P33076 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, protein C-terminus binding, RNA polymerase II transcription factor activity, transcription activator binding, ATP binding, transcription coactivator activity, ubiquitin binding, promoter binding, protein complex binding	nucleus	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription, response to interferon-gamma, positive regulation of MHC class II biosynthetic process, response to antibiotic, positive regulation of transcription from RNA polymerase II promoter, negative regulation of collagen biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	834	HVVQELPGRLSFLGTRLTPPD	PKA_group	11416140	LTP	1.00	MOD_PKA_2	-	-	0.30	-	medium
S	1050	PSLAASLLRLSLYNNCICDVG	PKA_group	11416140	LTP	0.18	MOD_PKA_2	-	LRR	0.04	-	medium

Substrate:

MLCK (Serine/threonine Kinase)

Seq-ID:

Q15746 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7250086 NCK1_HUMAN
MINT-7252174 P85A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
myosin light chain kinase activity, metal ion binding, ATP binding, actin binding, calmodulin binding	cytosol	protein amino acid phosphorylation, muscle contraction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	13	DVKLVASSHISKTSLSVDPSR	PKA_group	11964068	LTP	1.00		-	-	0.39	-	medium

Substrate:

Moesin (Adapter molecule)

Seq-ID:

P26038 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, cell adhesion molecule binding, receptor binding	filopodium, cytoplasm, cytoskeleton, nucleolus, microvillus membrane, extrinsic to membrane, apical plasma membrane	membrane to membrane docking, leukocyte cell-cell adhesion, leukocyte migration

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	558	NMRLGRDKYKTLRQIRQGNTK	PKA_group	15634677	LTP	0.98		-	ERM	0.69	-	medium

Substrate:

Mybpc3 (Myosin-binding protein)

Seq-ID:

O70468 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, myosin heavy chain binding, actin binding	A band	myosin filament assembly, heart morphogenesis, cardiac muscle contraction, regulation of heart rate, cell adhesion, sarcomere organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	273	LDLRSAFRRTSLAGAGRRTSD	PKA_group	20151718	LTP	1.00	MOD_PKA_1	-	-	0.46	-	low
S	282	TSLAGAGRRTSDSHEDAGTPD	PKA_group	20151718	LTP	0.15	MOD_PKA_1	-	-	0.67	-	low
S	302	DFSSLLKKRDSFRRDSKLEAP	PKA_group	20151718	LTP	0.20	MOD_PKA_1	-	-	0.44	-	low
S	307	LKKRDSFRRDSKLEAPAEEDV	PKA_group	20151718	LTP	0.30	MOD_PKA_1	-	-	0.46	-	low

Substrate:

Mybpc3 (Myosin-binding protein)

Seq-ID:

Q14896 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATPase activator activity, myosin heavy chain binding, structural constituent of muscle, titin binding, actin binding	C zone, striated myosin muscle thick filament	positive regulation of ATPase activity, regulation of striated muscle contraction, regulation of muscle filament sliding, cardiac muscle contraction, ventricular cardiac muscle tissue morphogenesis, cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	275	LDLLSAFRRTSLAGGGRRISD	PKA_group	20151718	LTP	1.00	MOD_PKA_1	-	-	0.30	-	low
S	275	LDLLSAFRRTSLAGGGRRISD	PKA_group	18802026	LTP	1.00	MOD_PKA_1	-	-	0.30	-	low
S	284	TSLAGGGRRISDSHEDTGILD	PKA_group	20151718	LTP	0.14	MOD_PKA_1	-	-	0.42	-	low
S	284	TSLAGGGRRISDSHEDTGILD	PKA_group	18802026	LTP	0.14	MOD_PKA_1	-	-	0.42	-	low
S	304	DFSSLLKKSSSFRTPRDSKLE	PKA_group	20151718	LTP	0.20	MOD_PKA_1	-	-	0.36	-	low
S	304	DFSSLLKKSSSFRTPRDSKLE	PKA_group	18802026	LTP	0.20	MOD_PKA_1	-	-	0.36	-	low
S	311	KSSSFRTPRDSKLEAPAEEDV	PKA_group	20151718	LTP	0.01	MOD_PKA_2	-	-	0.49	-	low

Substrate:

MYOM1 (structural constituent of muscle)

Seq-ID:

P52179 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of muscle	striated myosin muscle thick filament

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	482	AEKARLKSPLSTLDWTVIVTE	PKA_group	9029142	LTP	0.00		-	-	0.29	-	medium

Substrate:

Neurabin II protein (Cytoskeletal protein)

Seq-ID:

Q96SB3 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-62199 PP1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity, protein phosphatase 1 binding, actin binding	dendritic spine, cell junction, protein phosphatase type 1 complex, cytoskeleton, synapse, nucleoplasm	nervous system development, negative regulation of cell growth, cell cycle arrest, regulation of exit from mitosis, regulation of cell proliferation, regulation of cell growth by extracellular stimulus, RNA splicing, cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	94	PRASERGVRLSLPRASSLNEN	PKA_group	12417592	LTP	0.21	MOD_PKA_2	-	-	0.75	-	medium
S	100	GVRLSLPRASSLNENVDHSAL	PKA_group	12417592	LTP	1.00	MOD_PKA_2	-	-	0.62	-	medium

Substrate:

Neutrophil cytosol factor 1 (Neutrophil cytosol factor 1)

Seq-ID:

P14598 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-58638   TF65_HUMAN
MINT-66383   TRIM9_HUMAN
MINT-74863   ACTB_HUMAN
MINT-3973484   KPCA_HUMAN
MINT-3973536   KPCD_HUMAN
MINT-7135171   GNAI2_HUMAN
MINT-7300360   NCF4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3 domain binding, phosphoinositide binding, GTPase activity, GTP binding, electron carrier activity	cytosol, NADPH oxidase complex, soluble fraction	protein targeting to membrane, superoxide anion generation, cellular defense response, innate immune response, cell communication, respiratory burst

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	303	QIKRGAPPRRSSIRNAHSIHQ	PKA_group	7520867	LTP	1.00	MOD_PKA_1	-	-	0.76	1NG2	44.26%
S	320	SIHQRSRKRLSQDAYRRNSVR	PKA_group	8626435	LTP	1.00	MOD_PKA_1	-	-	0.59	1NG2	58.20%
S	320	SIHQRSRKRLSQDAYRRNSVR	PKA_group	7520867	LTP	1.00	MOD_PKA_1	-	-	0.59	1NG2	58.20%
S	328	RLSQDAYRRNSVRFLQQRRRQ	PKA_group	8626435	LTP	0.99	MOD_PKA_1	-	-	0.56	1NG2	0.00%
S	348	QARPGPQSPGSPLEEERQTQR	PKA_group	8626435	LTP	0.81	MOD_CK2_1	-	p47_phox_C	0.94	-	-
S	359	PLEEERQTQRSKPQPAVPPRP	PKA_group	8626435	LTP	0.71	MOD_PKA_2	-	p47_phox_C	0.94	-	-
S	370	KPQPAVPPRPSADLILNRCSE	PKA_group	8626435	LTP	1.00	MOD_PKA_2	-	p47_phox_C	0.80	-	-

Substrate:

NF-ATc1 (Transcription factor)

Seq-ID:

O95644 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-3319626 1433Z_HUMAN
MINT-6166975 OGT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
FK506 binding, transcription activator activity, promoter binding, sequence-specific DNA binding transcription factor activity, protein binding	cytoplasm, nucleus	intracellular signaling pathway, transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	245	RHSPSTSPRASVTEESWLGAR	PKA_group	9072970	LTP	1.00	MOD_PKA_2	-	-	0.73	-	low
S	269	PASPCNKRKYSLNGRQPPYSP	PKA_group	9072970	LTP	0.94	MOD_PKA_1	-	-	0.68	-	low
S	294	TPSPHGSPRVSVTDDSWLGNT	PKA_group	12351631	LTP	1.00	MOD_PKA_2	-	-	0.77	-	low

Substrate:

NFE2L1 (transcription cofactor activity, transcription factor activity)

Seq-ID:

Q14494 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, protein dimerization activity, transcription cofactor activity, sequence-specific DNA binding transcription factor activity	nucleus	transcription from RNA polymerase II promoter, heme biosynthetic process, anatomical structure morphogenesis, inflammatory response, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	599	LPPPSALKKGSKEKQADFLDK	PKA_group	15308669	LTP	0.20	MOD_PKA_1	-	-	0.62	-	medium

Substrate:

NIPP1 (RNA binding protein)

Seq-ID:

Q12972 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15257   CDC5L_HUMAN
MINT-62188   PP1A_HUMAN
MINT-64092   STC2_HUMAN
MINT-64094   SETB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding, protein serine/threonine phosphatase inhibitor activity, endonuclease activity, ribonuclease E activity, RNA binding, protein binding	spliceosomal complex, cytoplasm, nuclear speck	mRNA processing, transcription, regulation of transcription, RNA catabolic process, RNA splicing

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	178	EFNTAHNKRISTLTIEEGNLD	PKA_group	9407077	LTP	1.00	MOD_PKA_1	-	-	0.55	-	medium
S	199	IQRPKRKRKNSRVTFSEDDEI	PKA_group	9407077	LTP	0.19	MOD_PKA_1	-	-	0.70	-	medium

Substrate:

Nitric-oxide synthase, brain (Enzyme: Synthetase)

Seq-ID:

P29476 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-58323 AT2B4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amino acid binding, protein homodimerization activity, heme binding, cadmium ion binding, enzyme binding, NADP or NADPH binding, FAD binding, calmodulin binding, nitric-oxide synthase activity, FMN binding	dendritic spine, cytosol, nuclear membrane, synapse, photoreceptor inner segment, mitochondrial outer membrane, azurophil granule, perinuclear region of cytoplasm, sarcolemma	response to organic nitrogen, negative regulation of blood pressure, response to vitamin E, oxidation reduction, response to hypoxia, response to estrogen stimulus, response to organic cyclic substance, aging, response to heat, arginine catabolic process, negative regulation of insulin secretion, nitric oxide biosynthetic process, negative regulation of heart contraction, regulation of sensory perception of pain, response to ethanol, positive regulation of vasodilation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	374	QYYSSIKRFGSKAHMDRLEEV	PKA_group	1721813	LTP	1.00		-	NO_synthase	0.32	1OM4	25.41%

Substrate:

Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)

Seq-ID:

P29474 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
arginine binding, actin monomer binding, heme binding, cadmium ion binding, NADP or NADPH binding, FAD binding, calmodulin binding, nitric-oxide synthase activity, tetrahydrobiopterin binding, FMN binding	Golgi membrane, caveola, cytosol, cytoskeleton	regulation of blood vessel size, positive regulation of vasodilation, oxidation reduction, blood vessel remodeling, regulation of systemic arterial blood pressure by endothelin, anti-apoptosis, response to heat, positive regulation of guanylate cyclase activity, arginine catabolic process, negative regulation of muscle hyperplasia, positive regulation of angiogenesis, nitric oxide biosynthetic process, smooth muscle hyperplasia, endothelial cell migration, negative regulation of platelet activation, response to fluid shear stress, mitochondrion organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	633	VSSWRRKRKESSNTDSAGALG	PKA_group	12171920	LTP	0.04	MOD_PKA_1	-	Flavodoxin_1	0.47	-	-

Substrate:

Nopp140 (Transcription factor)

Seq-ID:

Q14978 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-73494 VE7_HPV16
MINT-3296095 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTP binding, ATP binding, protein binding	cytoplasm, nucleolus	rRNA processing, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	623	KRKKGEKRASSPFRRVREEEI	PKA_group	12167624	LTP	0.65	MOD_PKA_1	-	SRP40_C	0.71	-	medium

Substrate:

NPR-A (Guanylate cyclase)

Seq-ID:

P16066 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-61913 MCAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTP binding, guanylate cyclase activity, ATP binding, peptide receptor activity, G-protein coupled, protein kinase activity, natriuretic peptide receptor activity	integral to plasma membrane	regulation of blood vessel size, protein amino acid phosphorylation, diuresis, receptor guanylyl cyclase signaling pathway, negative regulation of angiogenesis, regulation of blood pressure, negative regulation of cell growth, natriuresis, regulation of vasodilation, regulation of vascular permeability

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	529	SLERHLRSAGSRLTLSGRGSN	PKA_group	9528788	LTP	1.00	MOD_PKA_2	-	STYKc	0.37	-	medium

Substrate:

Nuclear factor NF-kappa-B p105 subunit (Nuclear factor NF-kappa-B p105 subunit)

Seq-ID:

P19838 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-47827   M3K8_HUMAN
MINT-47861   IKBB_HUMAN
MINT-48545   TPR_HUMAN
MINT-48546   KCRB_HUMAN
MINT-48547   CLH1_HUMAN
MINT-48555   VIME_HUMAN
MINT-48556   ADT3_HUMAN
MINT-48557   DESP_HUMAN
MINT-48560   JIP4_HUMAN
MINT-48561   COPB2_HUMAN
MINT-48636   BAG2_HUMAN
MINT-48638   NEMO_HUMAN
MINT-48639   HS71L_HUMAN
MINT-48640   GRP78_HUMAN
MINT-48641   HSP7C_HUMAN
MINT-48642   HNRPF_HUMAN
MINT-48643   IKKA_HUMAN
MINT-48644   ADT2_HUMAN
MINT-48645   GRP75_HUMAN
MINT-48646   RUVB2_HUMAN
MINT-48648   IMA3_HUMAN
MINT-48650   DNJA1_HUMAN
MINT-48651   IMA4_HUMAN
MINT-48653   C1QBP_HUMAN
MINT-48654   EF1A2_HUMAN
MINT-48655   MATR3_HUMAN
MINT-48656   IKBA_HUMAN
MINT-48659   MYH10_HUMAN
MINT-48660   PYR1_HUMAN
MINT-48663   ACTG_HUMAN
MINT-48665   STUB1_HUMAN
MINT-48666   REL_HUMAN
MINT-48669   TBB6_HUMAN
MINT-48670   CALM_HUMAN
MINT-48671   NONO_HUMAN
MINT-48672   TBB5_HUMAN
MINT-48673   TBB4_HUMAN
MINT-48675   K1967_HUMAN
MINT-48677   DNJA3_HUMAN
MINT-48678   MYH9_HUMAN
MINT-48679   RS8_HUMAN
MINT-48680   SFPQ_HUMAN
MINT-48682   HS90A_HUMAN
MINT-48684   PRKDC_HUMAN
MINT-48685   MYL6_HUMAN
MINT-48687   HNRPM_HUMAN
MINT-48688   HS90B_HUMAN
MINT-48689   ML12A_HUMAN
MINT-48724   NFKB2_HUMAN
MINT-48996   RELB_HUMAN
MINT-50169   HDAC1_HUMAN
MINT-7023862   CTNB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
promoter binding, sequence-specific DNA binding transcription factor activity, protein binding	cytosol, I-kappaB/NF-kappaB complex, nucleoplasm	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, positive regulation of transcription, negative regulation of cellular protein metabolic process, apoptosis, anti-apoptosis, negative regulation of cholesterol transport, membrane protein intracellular domain proteolysis, positive regulation of lipid storage, signal transduction, inflammatory response, positive regulation of macrophage derived foam cell differentiation, negative regulation of vitamin D biosynthetic process, negative regulation of calcidiol 1-monooxygenase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	337	ASVFVQLRRKSDLETSEPKPF	PKA_group	12947093	LTP	1.00	MOD_PKA_1	-	IPT	0.42	1U3J	67.21%
S	337	ASVFVQLRRKSDLETSEPKPF	PKA_group	15642694	LTP	1.00	MOD_PKA_1	-	IPT	0.42	1U3J	67.21%

Substrate:

Octamer binding transcription factor 1 (Transcription factor)

Seq-ID:

P14859 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6803426 SP1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, protein binding		transcription, negative regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	385	GLSRRRKKRTSIETNIRVALE	PKA_group	1684878	LTP	1.00	MOD_PKA_1	-	HOX	0.43	1HF0	90.16%

Substrate:

Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR (Early response protein NAK1) (TR3 orphan receptor))

Seq-ID:

P22829 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
zinc ion binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity	nucleus	transcription

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	340	GMVKEVVRTDSLKGRRGRLPS	PKA_group	8227042	LTP	1.00		-	-	0.49	1CIT	104.92%
S	350	SLKGRRGRLPSKPKQPPDASP	PKA_group	8227042	LTP	1.00		-	-	0.78	1CIT	100.82%

Substrate:

PCTAIRE1 (Serine/threonine-protein kinase PCTAIRE-1)

Seq-ID:

Q00536 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cyclin-dependent protein kinase activity, ATP binding, protein binding		protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	12	DRMKKIKRQLSMTLRGGRGID	PKA_group	12154078	LTP	0.96		-	-	0.72	-	medium
S	110	RMRNHPPRKISTEDINKRLSL	PKA_group	12154078	LTP	0.99	MOD_PKA_1	-	-	0.68	-	medium
S	119	ISTEDINKRLSLPADIRLPEG	PKA_group	12154078	LTP	0.96	MOD_PKA_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.47	-	medium
S	153	KPLSRRLRRVSLSEIGFGKLE	PKA_group	12154078	LTP	0.96	MOD_PKA_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.23	-	medium

Substrate:

Perilipin (Storage protein)

Seq-ID:

P43884 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	lipid particle	lipid metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	81	WSMEPVVRRLSTQFTAANELA	PKA_group	11751901	LTP	0.07	MOD_PKA_1	-	Perilipin	0.30	-	medium
S	223	KAKPSLLRRVSTLANTLSRHT	PKA_group	11751901	LTP	0.06	MOD_PKA_1	-	Perilipin	0.54	-	medium
S	277	AAMQVVSRRQSEVRVPWLHNL	PKA_group	11751901	LTP	0.11	MOD_PKA_1	-	Perilipin	0.41	-	medium

Substrate:

Phenylalanine-4-hydroxylase (phenylalanine-4-hydroxylase (PAH) (from PhosphoBase))

Seq-ID:

P00439 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phenylalanine 4-monooxygenase activity		neurotransmitter biosynthetic process, oxidation reduction, L-phenylalanine catabolic process, catecholamine biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	LENPGLGRKLSDFGQETSYIE	PKA_group	12185072	LTP	0.43	MOD_PKA_1	-	-	0.36	-	medium

Substrate:

Phenylalanine-4-hydroxylase (phenylalanine-4-hydroxylase (PAH) (from PhosphoBase))

Seq-ID:

P04176 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
iron ion binding, amino acid binding, protein homodimerization activity, cofactor binding, phenylalanine 4-monooxygenase activity		oxidation reduction, L-phenylalanine catabolic process, protein amino acid hydroxylation, tyrosine biosynthetic process, tetrahydrobiopterin metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	LENGVLSRKLSDFGQETSYIE	PKA_group	7387651	LTP	0.54	MOD_PKA_1	-	-	0.27	-	-

Substrate:

Phosducin (phosducin (meka protein) (from PhosphoBase))

Seq-ID:

P19632 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytosol, photoreceptor outer segment, photoreceptor inner segment	visual perception, response to stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	73	DSKERFSRKMSVQEYELIHKD	PKA_group	2394752	LTP	1.00	MOD_PKA_1	-	Phosducin	0.44	1A0R	40.16%

Substrate:

Phosducin (phosducin (meka protein) (from PhosphoBase))

Seq-ID:

P20942 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytosol, photoreceptor outer segment, photoreceptor inner segment	visual perception, response to stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	73	DSKERMSRKMSIQEYELIHQD	PKA_group	2394752	LTP	1.00	MOD_PKA_1	-	Phosducin	0.54	-	-

Substrate:

Phosphodiesterase 3B (Enzyme: Phosphodiesterase)

Seq-ID:

Q13370 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase B binding, metal ion binding, cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	guanyl-nucleotide exchange factor complex, microsome, integral to membrane, Golgi apparatus, endoplasmic reticulum	cAMP catabolic process, signal transduction, negative regulation of cell adhesion mediated by integrin, negative regulation of cAMP-mediated signaling, cellular response to insulin stimulus, negative regulation of lipid catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	318	YGSCKIFRRPSLPCISREQMI	PKA_group	8626720	LTP	1.00	MOD_PKA_1	YWHAB 14-3-3	-	0.05	-	medium
S	318	YGSCKIFRRPSLPCISREQMI	PKA_group	17255105	LTP	1.00	MOD_PKA_1	YWHAB 14-3-3	-	0.05	-	medium

Substrate:

Phosphodiesterase 5A (Enzyme: Phosphodiesterase)

Seq-ID:

O76074 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cGMP binding, 3`,5`-cyclic-GMP phosphodiesterase activity, zinc ion binding		signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	102	SVPGTPTRKISASEFDRPLRP	PKA_group	12359732	LTP	1.00	MOD_PKA_1	-	-	0.54	-	medium
S	102	SVPGTPTRKISASEFDRPLRP	PKA_group	16690614	LTP	1.00	MOD_PKA_1	-	-	0.54	-	medium

Substrate:

Phospholamban (Integral membrane protein)

Seq-ID:

P26678 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium channel regulator activity, protein binding	sarcoplasmic reticulum, mitochondrial membrane, integral to membrane	blood circulation, regulation of calcium ion transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	YLTRSAIRRASTIEMPQQARQ	PKA_group	9468536	LTP	-	MOD_PKA_1	-	Phospholamban	0.12	-	-

Substrate:

Phospholamban (Integral membrane protein)

Seq-ID:

P61013 [Sus scrofa]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATPase inhibitor activity, calcium channel regulator activity	sarcoplasmic reticulum, mitochondrial membrane, integral to membrane	regulation of calcium ion transport, calcium ion transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	YLTRSAIRRASTIEMPQQARQ	PKA_group	2544595	LTP	-	MOD_PKA_1	-	Phospholamban	0.12	-	-

Substrate:

Phospholemman precursor (FXYD family)

Seq-ID:

O00168 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
chloride channel activity	integral to plasma membrane, chloride channel complex	muscle contraction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	83	PDEEEGTFRSSIRRLSTRRR	PKA_group	10556585	LTP	0.08	MOD_PKA_2	-	-	0.52	-	-

Substrate:

Phosphorylase b kinase alpha regulatory chain, skeletal muscle isoform (Enzyme: Phosphorylase)

Seq-ID:

P18688 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calmodulin binding, glucan 1,4-alpha-glucosidase activity	plasma membrane	glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1018	EIKQVEFRRLSISTESQPNGG	PKA_group	2567185	LTP	0.45	MOD_PKA_1	-	PHK_AB	0.52	-	low

Substrate:

Phosphorylase b kinase beta regulatory chain (phosphorylase b kinase beta regulatory chain (from PhosphoBase))

Seq-ID:

P12798 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calmodulin binding, glucan 1,4-alpha-glucosidase activity	plasma membrane	glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	27	ERRARTKRSGSVYEPLKSINL	PKA_group	164350	LTP	-		-	PHK_AB	0.39	-	medium

Substrate:

Phytochrome A type 3 (phytochrome A type 3 (AP3) (from PhosphoBase))

Seq-ID:

P06593 [Avena sativa]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
G-protein coupled photoreceptor activity, protein homodimerization activity, ATP binding, two-component sensor activity	membrane	peptidyl-histidine phosphorylation, transcription, red, far-red light phototransduction, protein-chromophore linkage, sensory perception, regulation of transcription, DNA-dependent, protein-tetrapyrrole linkage

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	18	SSSSSRNRQSSQARVLAQTTL	PKA_group	2354157	LTP	0.18	MOD_PKA_2	-	-	0.64	-	low
S	599	NDASKPKREASLDNQIGDLKL	PKA_group	2354157	LTP	0.08		-	-	0.46	-	low

Substrate:

PIN1 (protein binding)

Seq-ID:

Q13526 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15316   TOP2A_HUMAN
MINT-15821   CSK21_HUMAN
MINT-19990   P53_HUMAN
MINT-63063   SOCS3_HUMAN
MINT-63769   LEPR_HUMAN
MINT-64243   MTFR1_HUMAN
MINT-64894   CHSS2_HUMAN
MINT-65416   DDX24_HUMAN
MINT-66285   T22D4_HUMAN
MINT-66396   RAI1_HUMAN
MINT-67692   HNRPC_HUMAN
MINT-67798   RBPMS_HUMAN
MINT-67901   RBBP8_HUMAN
MINT-2861778   UBQL4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoserine binding, phosphothreonine binding, peptidyl-prolyl cis-trans isomerase activity	nucleus	protein folding, negative regulation of transforming growth factor beta receptor signaling pathway, cell cycle, regulation of pathway-restricted SMAD protein phosphorylation, regulation of mitosis, positive regulation of ubiquitin-protein ligase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	KLPPGWEKRMSRSSGRVYYFN	PKA_group	11723108	LTP	1.00	MOD_PKA_1	-	WW	0.43	1PIN	34.43%

Substrate:

PLC beta 3 (Enzyme: Phospholipase)

Seq-ID:

Q01970 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-62354   PARD3_HUMAN
MINT-62355   PAR6A_HUMAN
MINT-73251   NHRF1_HUMAN
MINT-73254   EZRI_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, phosphoinositide phospholipase C activity, signal transducer activity	cytosol	lipid catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1105	QKILDRKRHNSISEAKMRDKH	PKA_group	10893237	LTP	0.35		-	PLC-beta_C	0.66	-	medium
S	1105	QKILDRKRHNSISEAKMRDKH	PKA_group	9660757	LTP	0.35		-	PLC-beta_C	0.66	-	medium

Substrate:

PLC gamma 1 (Major substrate for eparin binding growth factor)

Seq-ID:

P19174 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19688   RBP2_MOUSE
MINT-74678   EGFR_HUMAN
MINT-74680   ERBB2_HUMAN
MINT-74682   ERBB3_HUMAN
MINT-7146767   AKT1_HUMAN
MINT-7229970   RAC1_HUMAN
MINT-7231507   PLD1_HUMAN
MINT-7252402   ICAL_HUMAN
MINT-7252438   TRAIP_HUMAN
MINT-7252450   SNX17_HUMAN
MINT-7252486   ASAP2_HUMAN
MINT-7252498   ARHGB_HUMAN
MINT-7252534   ASAP1_HUMAN
MINT-7252546   RRAS_HUMAN
MINT-7252558   M4K1_HUMAN
MINT-7252594   GHR_HUMAN
MINT-7252618   RGS7_HUMAN
MINT-7252642   CKAP5_HUMAN
MINT-7252666   JAK2_HUMAN
MINT-7252678   SOS1_HUMAN
MINT-7252690   FLNB_HUMAN
MINT-7252714   FLNA_HUMAN
MINT-7252738   ABL1_HUMAN
MINT-7252750   SUV92_HUMAN
MINT-7252762   SC24B_HUMAN
MINT-7252786   FCG2B_HUMAN
MINT-7252798   FCG2C_HUMAN
MINT-7252810   PHAR2_HUMAN
MINT-7252846   FANCA_HUMAN
MINT-7252858   TGON2_HUMAN
MINT-7252882   CAF1A_HUMAN
MINT-7252894   MAP4_HUMAN
MINT-7252954   SHAN2_HUMAN
MINT-7252966   DNLI3_HUMAN
MINT-7252978   NELFB_HUMAN
MINT-7253038   DTBP1_HUMAN
MINT-7253050   ABL2_HUMAN
MINT-7253062   AKAP2_HUMAN
MINT-7253086   FLNC_HUMAN
MINT-7253122   MINT_HUMAN
MINT-7253146   LIPA4_HUMAN
MINT-7253158   ADNP_HUMAN
MINT-7306637   LCP2_HUMAN
MINT-7309951   SCRB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoinositide phospholipase C activity, receptor signaling protein activity	plasma membrane, cytosol	interspecies interaction between organisms, phospholipid catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1248	QLFHGRAREGSFESRYQQPFE	PKA_group	1370476	LTP	0.94		-	-	0.40	-	medium

Substrate:

PMCA1 (calcium-transporting ATPase plasma membreane (calcium pump) (from PhosphoBase))

Seq-ID:

P20020 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-69534 BCR_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, ATP binding, calcium-transporting ATPase activity, calmodulin binding, protein binding	integral to plasma membrane	ATP biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1178	EGLEKPESRSSIHNFMTHPEF	PKA_group	2548572	LTP	0.77	MOD_PKA_2	-	-	0.66	-	medium

Substrate:

Potassium voltage-gated channel subfamily H member 2 (potassium ion transport)

Seq-ID:

Q12809 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
delayed rectifier potassium channel activity, two-component sensor activity	voltage-gated potassium channel complex	muscle contraction, blood circulation, regulation of heart contraction, two-component signal transduction system (phosphorelay), regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	283	RESCASVRRASSADDIEAMRA	PKA_group	11953308	LTP	0.80	MOD_PKA_1	YWHAE 14-3-3	-	0.55	-	low
S	1137	LPQEGPTRRLSLPGQLGALTS	PKA_group	11953308	LTP	1.00	MOD_PKA_1	YWHAE 14-3-3	-	0.79	-	low

Substrate:

PPP1R14D (Protein phosphatase)

Seq-ID:

Q9NXH3 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity, protein binding	cytoplasm	regulation of phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	58	IPRSRRPSRLTVKYDRGQLQR	PKA_group	12974676	LTP	1.00	MOD_PKA_1	-	PP1_inhibitor	0.54	-	low

Substrate:

Presenilin 1 (Presenilin 1 (PS-1) (S182 protein))

Seq-ID:

P49768 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14193   PKP4_HUMAN
MINT-15987   FLNB_HUMAN
MINT-16205   B2CL1_HUMAN
MINT-17726   FLNA_HUMAN
MINT-49819   CADH1_HUMAN
MINT-2837737   GSK3B_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium channel activity, beta-catenin binding, endopeptidase activity, PDZ domain binding	centrosome, Golgi membrane, smooth endoplasmic reticulum, integral to plasma membrane, cell surface, kinetochore, nuclear outer membrane, endoplasmic reticulum membrane, rough endoplasmic reticulum, gamma-secretase complex	induction of apoptosis by extracellular signals, membrane protein ectodomain proteolysis, anti-apoptosis, Notch receptor processing, membrane protein intracellular domain proteolysis, Notch signaling pathway, amyloid precursor protein catabolic process, cell-cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	310	EGDPEAQRRVSKNSKYNAEST	PKA_group	14576165	LTP	0.25	MOD_PKA_1	-	PSN	0.66	-	medium

Substrate:

Prostaglandin E2 receptor, EP4 subtype (G protein coupled receptor)

Seq-ID:

P35408 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
prostaglandin E receptor activity	plasma membrane, integral to membrane	immune response, G-protein signaling, coupled to cAMP nucleotide second messenger

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	222	RMHRQFMRRTSLGTEQHHAAA	PKA_group	11597569	LTP	1.00	MOD_PKA_1	-	7tm_1	0.25	-	medium
S	259	PRLSDFRRRRSFRRIAGAEIQ	PKA_group	11597569	LTP	1.00	MOD_PKA_1	-	7tm_1	0.11	-	medium

Substrate:

Protamine YI (protamine (clupeine) YI (from PhosphoBase))

Seq-ID:

P69013 [Clupea pallasii]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	spermatogenesis, cell differentiation, multicellular organismal development, chromosome condensation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	ARRRRSSSRPIRRRRPRR	PKA_group	202510	LTP	-	MOD_PKA_1	-	-	0.98	-	medium

Substrate:

Protamine YII (protamine (clupeine) YII (from PhosphoBase))

Seq-ID:

P69009 [Clupea pallasii]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	spermatogenesis, cell differentiation, multicellular organismal development, chromosome condensation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	5	PRRRTRRASRPVRRR	PKA_group	3142476	LTP	-	MOD_PKA_1	-	-	0.97	-	medium
S	9	PRRRTRRASRPVRRRRPRR	PKA_group	202510	LTP	-	MOD_PKA_1	-	-	0.97	-	medium

Substrate:

Protamine Z (protamines Z1 and Z2 (thynnins Z1 and Z2) (from PhosphoBase))

Seq-ID:

P69011 [Clupea pallasii]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	spermatogenesis, cell differentiation, multicellular organismal development, chromosome condensation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	ARRRRSRRASRPVRRR	PKA_group	3142476	LTP	-	MOD_PKA_1	-	-	0.96	-	medium
S	10	ARRRRSRRASRPVRRRRPRR	PKA_group	3142476	LTP	-	MOD_PKA_1	-	-	0.96	-	medium

Substrate:

Protein phosphatase 1, regulatory subunit 3A (Serine/threonine phosphatase)

Seq-ID:

Q16821 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	integral to membrane	glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	48	SPQPSRRGSDSSEDIYLDTPS	PKA_group	10648825	LTP	1.00	MOD_PKA_1	-	-	0.68	-	medium
S	65	DTPSSGTRRVSFADSFGFNLV	PKA_group	10648825	LTP	1.00	MOD_PKA_1	-	-	0.22	-	medium

Substrate:

PTBP1 (poly-pyrimidine tract binding, protein binding)

Seq-ID:

P26599 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-62326   ZMYM2_HUMAN
MINT-62329   SFPQ_HUMAN
MINT-75016   NPM_HUMAN
MINT-2855482   PCBP1_HUMAN
MINT-3318428   1433Z_HUMAN
MINT-7974432   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nucleotide binding, poly-pyrimidine tract binding, protein binding	nucleolus, nucleoplasm, heterogeneous nuclear ribonucleoprotein complex	mRNA processing, RNA splicing

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	PDIAVGTKRGSDELFSTCVTN	PKA_group	12851456	LTP	1.00	MOD_PKA_1	-	-	0.34	-	-

Substrate:

PTH/PTHr receptor (parathyroid hormone/parathyroid hormone-related peptide receptor (from PhosphoBase))

Seq-ID:

P25107 [Didelphis virginiana]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
parathyroid hormone receptor activity	plasma membrane, integral to membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	467	NGEVQAEIKKSWSRWTLALDF	PKA_group	9157772	LTP	0.20		-	-	0.11	-	medium
S	469	EVQAEIKKSWSRWTLALDFKR	PKA_group	9157772	LTP	0.28	MOD_PKA_2	-	-	0.14	-	medium
S	485	LDFKRKARSGSSTYSYGPMVS	PKA_group	9157772	LTP	1.00		-	-	0.32	-	medium

Substrate:

Pyruvate kinase, isozymes R/L (pyruvate kinase, isoenzyme L (from PhosphoBase))

Seq-ID:

P12928 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
potassium ion binding, magnesium ion binding, ATP binding, pyruvate kinase activity	cytosol, soluble fraction	pyruvate biosynthetic process, response to hypoxia, ATP biosynthetic process, response to organic cyclic substance, response to lithium ion, response to cAMP, response to heat, response to glucose stimulus, response to nutrient, response to ATP, cellular response to insulin stimulus, glycolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	43	GGPAGYLRRASVAQLTQELGT	PKA_group	1106423	LTP	-	MOD_PKA_1	-	-	0.31	-	medium

Substrate:

Raf1 (RAF proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P04049 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19324   KPYM_HUMAN
MINT-24923   RAP1A_HUMAN
MINT-45800   1433Z_HUMAN
MINT-51053   K1C19_HUMAN
MINT-51055   K1C18_HUMAN
MINT-51056   K2C8_HUMAN
MINT-56513   CNKR1_HUMAN
MINT-3389399   PAK1_HUMAN
MINT-3389607   PEBP1_HUMAN
MINT-3975386   1433S_HUMAN
MINT-6946517   RASH_HUMAN
MINT-7014370   MP2K1_HUMAN
MINT-7014449   AKT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, metal ion binding, receptor signaling protein activity, ATP binding, protein binding	plasma membrane, cytosol, mitochondrial outer membrane	protein amino acid phosphorylation, negative regulation of cell proliferation, apoptosis, Ras protein signal transduction, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	43	VQQFGYQRRASDDGKLTDPSK	PKA_group	11971957	LTP	1.00	MOD_PKA_1	-	-	0.48	-	medium
S	259	GSLSQRQRSTSTPNVHMVSTT	PKA_group	11971957	LTP	1.00	MOD_PKB_1	SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.73	-	medium
S	621	HSLPKINRSASEPSLHRAAHT	PKA_group	11971957	LTP	0.99		SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.49	-	medium

Substrate:

Rap1GAP (GTPase activating protein)

Seq-ID:

P47736 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-3308267 1433Z_HUMAN
MINT-6543629 RAP1B_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, GTPase activator activity, Ras GTPase binding	Golgi membrane	signal transduction, regulation of Ras GTPase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	490	VPGKSPTRKKSGPFGSRRSSA	PKA_group	1406653	LTP	0.92	MOD_PKA_1	-	-	0.79	-	low
S	499	KSGPFGSRRSSAIGIENIQEV	PKA_group	1406653	LTP	1.00	MOD_PKA_1	-	-	0.72	-	low

Substrate:

Ras related protein 1A (GTPase)

Seq-ID:

P62834 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-24923 RAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding	plasma membrane, cytosol

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	180	PVEKKKPKKKSCLLL	PKA_group	9867809	LTP	0.09	MOD_PKA_1	-	-	0.31	-	medium

Substrate:

Ras-related protein Rap-1b (ras-related protein rap-1b (GTP-binding protein smg p21b) (from PhosphoBase))

Seq-ID:

P61224 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48838 M3K14_HUMAN
MINT-6543629 RPGP1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GDP binding, GTPase activity, GTP binding, protein binding	plasma membrane, cytosol

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	179	TPVPGKARKKSSCQLL	PKA_group	1696481	LTP	0.55	MOD_PKA_1	-	-	0.42	-	low
S	179	TPVPGKARKKSSCQLL	PKA_group	1551424	LTP	0.55	MOD_PKA_1	-	-	0.42	-	low

Substrate:

Regulator of G-protein signaling 10, isoform a (GTPase activating protein)

Seq-ID:

O43665 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
signal transducer activity, protein binding		negative regulation of signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	168	PDAQTAAKRASRIYNT	PKA_group	11443111	LTP	1.00	MOD_PKA_1	-	-	0.50	-	-

Substrate:

REL (c-Rel proto-oncogene protein (p68) (from PhosphoBase))

Seq-ID:

P16236 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity	cytoplasm, nucleus	DNA fragmentation involved in apoptotic nuclear change

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	266	ITVKMQLRRPSDQEVSEPMDF	PKA_group	8437855	LTP	0.96	MOD_PKA_1	-	IPT	0.57	1GJI	68.85%

Substrate:

RGS14 (GTPase activating protein)

Seq-ID:

O43566 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor signaling protein activity, GTPase activator activity	membrane	negative regulation of signal transduction, regulation of G-protein coupled receptor protein signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	260	GTANAALRRESQGSLNSSASL	PKA_group	12534294	LTP	1.00	MOD_PKA_1	-	-	0.51	-	-
T	496	VPSSATGKRQTCDIEGLVELL	PKA_group	12534294	LTP	0.71	MOD_PKA_1	-	-	0.46	-	-

Substrate:

Rho guanine nucleotide exchange factor 7 (RAC1 guanine nucleotide exchange factor (GEF))

Seq-ID:

Q14155-1 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-56630 CBLB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, protein binding	cytosol	induction of apoptosis by extracellular signals, apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	516	LPKRKPERKPSDEEFASRKST	PKA_group	15513924	LTP	1.00	MOD_PKA_1	-	-	0.80	-	medium
T	526	SDEEFASRKSTAALEEDAQIL	PKA_group	15513924	LTP	1.00	MOD_PKA_1	-	-	0.59	-	medium

Substrate:

Rhodopsin kinase (rhodopsin kinase (EC 2.7.1.125) (RhK) (from PhosphoBase))

Seq-ID:

Q15835 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
rhodopsin kinase activity, G-protein coupled receptor kinase activity, ATP binding, signal transducer activity	membrane	rhodopsin mediated phototransduction, regulation of G-protein coupled receptor protein signaling pathway, rhodopsin mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	ANSAFIAARGSFDGSSSQPSR	PKA_group	15946941	LTP	0.31	MOD_PKA_2	-	-	0.37	-	low

Substrate:

Ryanodine receptor 1 (ryanodine receptor, skeletal muscle (calcium release channel) (from PhosphoBase))

Seq-ID:

P11716 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, calcium ion binding, ryanodine-sensitive calcium-release channel activity, calmodulin binding	terminal cisterna, integral to membrane	cellular calcium ion homeostasis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2843	RTEKKKTRKISQTAQTYDPRE	PKA_group	8380342	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium

Substrate:

Ryanodine receptor 2 (ryanodine receptor, cardiac muscle (from PhosphoBase))

Seq-ID:

Q92736 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19826 DYN2_MOUSE
MINT-61836 SMAD5_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, calcium ion binding, identical protein binding, ryanodine-sensitive calcium-release channel activity, protein kinase A regulatory subunit binding, suramin binding, calmodulin binding, protein kinase A catalytic subunit binding	plasma membrane, calcium channel complex, plasma membrane enriched fraction, sarcoplasmic reticulum membrane	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to hypoxia, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, cardiac muscle contraction, induction of apoptosis by ionic changes, response to caffeine, detection of calcium ion, response to redox state

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2031	SDLTIRGRLLSLVEKVTYLKK	PKA_group	16407108	LTP	0.00		-	-	0.16	-	medium
S	2031	SDLTIRGRLLSLVEKVTYLKK	PKA_group	15790957	LTP	0.00		-	-	0.16	-	medium
S	2808	MALYNRTRRISQTSQVSVDAA	PKA_group	10830164	LTP	0.85	MOD_PKA_1	-	-	0.42	-	medium
S	2808	MALYNRTRRISQTSQVSVDAA	PKA_group	15790957	LTP	0.85	MOD_PKA_1	-	-	0.42	-	medium

Substrate:

Ryanodine receptor 2 (ryanodine receptor, cardiac muscle (from PhosphoBase))

Seq-ID:

ENSMUSP00000050824 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, ryanodine-sensitive calcium-release channel activity	sarcoplasmic reticulum membrane, Z disc	response to caffeine

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2019	NDLTIRGRLLSLVEKVTYLKK	PKA_group	15790957	LTP	0.85		-	-	0.16	-	medium
S	2019	NDLTIRGRLLSLVEKVTYLKK	PKA_group	16483256	LTP	0.85		-	-	0.16	-	medium

Substrate:

S-protein (Vitronectin precursor (Serum spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B)

Seq-ID:

P04004 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
scavenger receptor activity, heparin binding, integrin binding	alphav-beta3 integrin-vitronectin complex, extracellular space	positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein binding, positive regulation of wound healing, positive regulation of smooth muscle cell migration, immune response, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of receptor-mediated endocytosis, negative regulation of endopeptidase activity, cell-matrix adhesion, cell adhesion mediated by integrin, negative regulation of blood coagulation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	397	RGRNQNSRRPSRATWLSLFSS	PKA_group	1696913	LTP	1.00	MOD_PKA_1	-	-	0.46	-	-

Substrate:

Serine/threonine-protein kinase Sgk1 (Serine/threonine kinase)

Seq-ID:

O00141 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-56642 CREB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein binding	plasma membrane, nucleus, endoplasmic reticulum	protein amino acid phosphorylation, response to stress, apoptosis, sodium ion transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	369	NWDDLINKKITPPFNPNVSGP	PKA_group	11096081	LTP	0.87		-	S_TK_X	0.37	2R5T	85.62%

Substrate:

Serotonin acetylase (Enzyme: Acyltransferase)

Seq-ID:

Q16613 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
aralkylamine N-acetyltransferase activity	cytosol	melatonin biosynthetic process, circadian rhythm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	31	PESPSCQRRHTLPASEFRCLT	PKA_group	11336675	LTP	1.00	MOD_PKA_1	-	-	0.35	-	medium
S	205	LRGHPFLRRNSGC	PKA_group	11336675	LTP	0.23		-	-	0.19	-	medium

Substrate:

SNARE-associated protein Snapin (Unclassified)

Seq-ID:

Q9Z266 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3389911 KC1D_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cell junction, cytosol, synaptic vesicle membrane, synaptosome	exocytosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	50	LDSHVHAVRESQVELREQIDN	PKA_group	11283605	LTP	1.00	MOD_PKA_2	-	COIL	0.45	-	low

Substrate:

Sodium bicarbonate cotransporter (Membrane transport protein)

Seq-ID:

Q9Y6R1 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
inorganic anion exchanger activity, sodium:bicarbonate symporter activity	basolateral plasma membrane, integral to plasma membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1026	DEKKKKKKKGSLDSDNDDSDC	PKA_group	11744745	LTP	0.65	MOD_PKA_1	-	-	0.69	-	medium

Substrate:

Sodium channel protein (sodium channel protein (from PhosphoBase))

Seq-ID:

P02719 [Electrophorus electricus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
voltage-gated sodium channel activity	voltage-gated sodium channel complex

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	MARKFSSARPEMFRRF	PKA_group	2557902	LTP	0.04	MOD_PKA_1	-	-	0.34	-	medium
S	7	MARKFSSARPEMFRRFT	PKA_group	2557902	LTP	0.00	MOD_PKA_1	-	-	0.34	-	medium
T	17	SARPEMFRRFTPDSLEEIEAF	PKA_group	2557902	LTP	1.00		-	-	0.34	-	medium
S	1776	KPMLDKPRMPSLSVPETYPIQ	PKA_group	2557902	LTP	0.11		-	-	0.46	-	medium

Substrate:

Sodium channel protein type II alpha subunit (sodium channel protein, brain II alpha subunit (from PhosphoBase))

Seq-ID:

P04775 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
voltage-gated sodium channel activity, sodium ion binding, leucine zipper domain binding	voltage-gated sodium channel complex, initial segment, node of Ranvier, synaptosome	myelination

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	573	RGSLFSPRRNSRASLFNFKGR	PKA_group	8262976	LTP	1.00	MOD_PKA_1	-	-	0.42	-	-
S	610	TFEDNDSRRDSLFVPHRHGER	PKA_group	8262976	LTP	1.00	MOD_PKA_1	-	-	0.72	-	-
S	623	VPHRHGERRPSNVSQASRASR	PKA_group	8262976	LTP	1.00	MOD_PKA_1	-	-	0.79	-	-
S	687	TETEIRKRRSSSYHVSMDLLE	PKA_group	8262976	LTP	0.35	MOD_PKA_1	-	-	0.45	-	-

Substrate:

Solute carrier family,member 2 (Membrane transport protein)

Seq-ID:

P11168 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	membrane fraction, integral to plasma membrane	carbohydrate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	491	FFKVPETKGKSFEEIAAEFQK	PKA_group	8626492	LTP	0.21	-	Sugar_tr	0.10	-	medium
S	503	EEIAAEFQKKSGSAHRPKAAV	PKA_group	8626492	LTP	0.07	-	-	0.17	-	medium
S	505	IAAEFQKKSGSAHRPKAAVEM	PKA_group	8626492	LTP	0.28	-	-	0.15	-	medium

Substrate:

SOX9 (specific RNA polymerase II transcription fa...)

Seq-ID:

P48436 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
specific RNA polymerase II transcription factor activity	nucleus	transcription

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	64	PKGEPDLKKESEEDKFPVCIR	PKA_group	10805756	LTP	0.27	MOD_PKA_1	-	-	0.59	-	medium
S	181	DYKYQPRRRKSVKNGQAEAEE	PKA_group	10805756	LTP	0.98	MOD_PKA_1	-	-	0.82	-	medium
S	181	DYKYQPRRRKSVKNGQAEAEE	PKA_group	11120880	LTP	0.98	MOD_PKA_1	-	-	0.82	-	medium
S	181	DYKYQPRRRKSVKNGQAEAEE	PKA_group	15889150	LTP	0.98	MOD_PKA_1	-	-	0.82	-	medium

Substrate:

spdya-A (RINGO/Speedy protein 1-A)

Seq-ID:

Q9PU13 [Xenopus laevis]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-17807 CDC2A_XENLA

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding, cyclin binding	nucleus	mRNA polyadenylation, oocyte maturation, positive regulation of meiotic cell cycle, positive regulation of cyclin-dependent protein kinase activity, activation of MAPK activity, meiotic G2/MI transition, multicellular organismal development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	12	RHMQSVTRATSICGSGVKQVI	PKA_group	16964245	LTP	0.08	MOD_PKA_2	-	-	0.34	-	medium
S	180	VSRRCCDEVMSKDPTHWAWLR	PKA_group	16964245	LTP	0.00		-	-	0.13	-	medium

Substrate:

Src (Proto-oncogene tyrosine-protein kinase Src)

Seq-ID:

P00523 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15440   HNRPK_RAT
MINT-16809   KHDR1_HUMAN
MINT-17269   SHC1_HUMAN
MINT-7212640   HCN2_MOUSE
MINT-7306585   LCP2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
non-membrane spanning protein tyrosine kinase activity, ATP binding		signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	17	KPKDPSQRRRSLEPPDSTHHG	PKA_group	2423705	LTP	0.24	MOD_PKA_1	-	-	0.94	-	-

Substrate:

Src (Proto-oncogene tyrosine-protein kinase Src)

Seq-ID:

P12931 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14765   DDR2_HUMAN
MINT-15459   CAV1_HUMAN
MINT-46002   CTNB1_MOUSE
MINT-50376   RASH_HUMAN
MINT-62340   KPCD_HUMAN
MINT-62342   CDCP1_HUMAN
MINT-65953   DYN1_HUMAN
MINT-65954   DYN2_HUMAN
MINT-68512   PDC6I_HUMAN
MINT-74753   ERBB3_HUMAN
MINT-2792760   PAK2_HUMAN
MINT-2793013   ADA15_HUMAN
MINT-2840132   TLR3_HUMAN
MINT-3381308   FAK1_HUMAN
MINT-3381360   FYN_HUMAN
MINT-4051815   ADRB2_HUMAN
MINT-4961196   AFAD_HUMAN
MINT-4980122   SNIP_MOUSE
MINT-5210599   SNIP_HUMAN
MINT-6539730   CBL_HUMAN
MINT-6771405   FAK1_MOUSE
MINT-6794909   ACTS_HUMAN
MINT-6795322   ACTN1_HUMAN
MINT-6795447   PTN1_HUMAN
MINT-7035260   HNRPK_HUMAN
MINT-7040283   CBLB_HUMAN
MINT-7104422   BCAR1_HUMAN
MINT-7145938   RL10_HUMAN
MINT-7244986   ASAP1_HUMAN
MINT-7244998   FANCA_HUMAN
MINT-7245022   PHAR2_HUMAN
MINT-7245034   ABL1_HUMAN
MINT-7245058   DLGP4_HUMAN
MINT-7245070   SNX17_HUMAN
MINT-7245106   RTN4_HUMAN
MINT-7245118   ASAP2_HUMAN
MINT-7245142   E41L3_HUMAN
MINT-7245154   ICAL_HUMAN
MINT-7245214   FCG2B_HUMAN
MINT-7245226   FCG2C_HUMAN
MINT-7245334   SHAN2_HUMAN
MINT-7245346   SHRM2_HUMAN
MINT-7245358   DNLI3_HUMAN
MINT-7245370   EIF3D_HUMAN
MINT-7245406   HCN2_HUMAN
MINT-7245490   CKAP5_HUMAN
MINT-7245502   M4K1_HUMAN
MINT-7245538   RPP38_HUMAN
MINT-7245562   SP1_HUMAN
MINT-7245574   DOCK1_HUMAN
MINT-7245586   RLGPB_HUMAN
MINT-7245598   ABL2_HUMAN
MINT-7245610   CELR2_HUMAN
MINT-7245622   SOS1_HUMAN
MINT-7245634   AKAP6_HUMAN
MINT-7245670   DPOD1_HUMAN
MINT-7245682   DAG1_HUMAN
MINT-7245694   SNX3_HUMAN
MINT-7245730   KI67_HUMAN
MINT-7245742   CD97_HUMAN
MINT-7245754   RPGF1_HUMAN
MINT-7245778   ACAP1_HUMAN
MINT-7245790   PRIC3_HUMAN
MINT-7245814   AKAP2_HUMAN
MINT-7245826   RRAS_HUMAN
MINT-7296136   P85A_HUMAN
MINT-7296149   ACTB_HUMAN
MINT-7306598   LCP2_HUMAN
MINT-7552515   PTPRA_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3/SH2 adaptor activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, integrin binding, SH2 domain binding	caveola, cytosol	protein amino acid phosphorylation, regulation of bone resorption, signal complex assembly, regulation of vascular permeability, response to interleukin-1, interspecies interaction between organisms, Ras protein signal transduction, positive regulation of integrin activation, intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	17	KPKDASQRRRSLEPAENVHGA	PKA_group	11804588	LTP	0.24	MOD_PKA_1	-	-	0.88	-	-

Substrate:

Stathmin (stathmin (phosphoprotein p19) (oncoprotein 18) (Op18) (from PhosphoBase))

Seq-ID:

P16949 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-2860477 UBQL4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
signal transducer activity, tubulin binding	cytoplasm, microtubule	intracellular signaling pathway, nervous system development, mitotic spindle organization, cell differentiation, microtubule depolymerization, response to virus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	63	KLEAAEERRKSHEAEVLKQLA	PKA_group	10913145	LTP	0.81	MOD_PKA_1	-	COIL	0.67	-	medium
S	63	KLEAAEERRKSHEAEVLKQLA	PKA_group	11415983	LTP	0.81	MOD_PKA_1	-	COIL	0.67	-	medium

Substrate:

Stathmin (stathmin (phosphoprotein p19) (oncoprotein 18) (Op18) (from PhosphoBase))

Seq-ID:

P54227 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cytoplasm, microtubule	positive regulation of cellular component movement, negative regulation of microtubule polymerization, axonogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	16	IQVKELEKRASGQAFELILSP	PKA_group	8376365	LTP	0.93	MOD_PKA_1	-	Stathmin	0.46	-	low
S	63	KLEAAEERRKSHEAEVLKQLA	PKA_group	8376365	LTP	0.81	MOD_PKA_1	-	COIL	0.67	-	low

Substrate:

STK24 (protein kinase activity)

Seq-ID:

Q9Y6E0 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, protein binding	cytosol, nucleoplasm	protein amino acid phosphorylation, signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	18	WGLALNKRRATLPHPGGSTNL	PKA_group	10644707	LTP	0.00	MOD_PKA_1	-	-	0.41	-	-

Substrate:

Sucrase isomaltase (Enzyme: Glucosidase)

Seq-ID:

P14410 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sucrose alpha-glucosidase activity, oligo-1,6-glucosidase activity	brush border, integral to membrane, Golgi apparatus, apical plasma membrane	carbohydrate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	7	MARKKFSGLEISLIVLF	PKA_group	8521865	LTP	1.00	MOD_PKA_1	-	SIGNAL	0.02	-	low

Substrate:

Synapsin II (Unclassified)

Seq-ID:

Q92777 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
catalytic activity, ATP binding	cell junction, synaptic vesicle	neurotransmitter secretion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	10	MMNFLRRRLSDSSFIANLPN	PKA_group	10571231	LTP	1.00	MOD_PKA_1	-	Synapsin_N	0.52	-	low

Substrate:

Synapsin-1 (Synapsin I (Brain protein 4.1))

Seq-ID:

P09951 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
catalytic activity, ATP binding, actin binding	cell junction, Golgi apparatus	neurotransmitter secretion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	9	MNYLRRRLSDSNFMANLPN	PKA_group	3118371	LTP	1.00	MOD_PKA_1	-	Synapsin_N	0.48	-	medium

Substrate:

Synapsin-1 (Synapsin I (Brain protein 4.1))

Seq-ID:

P17599 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
catalytic activity, ATP binding, actin binding	synaptonemal complex, cell junction, synaptic vesicle membrane, Golgi apparatus	neurotransmitter secretion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	9	MNYLRRRLSDSNFMANLPN	PKA_group	3118371	LTP	1.00	MOD_PKA_1	-	Synapsin_N	0.50	-	low

Substrate:

TAL-1 protein (Transcription factor)

Seq-ID:

P17542 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7254852 CRK_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
histone deacetylase binding, promoter binding, sequence-specific DNA binding transcription factor activity	nucleus	regulation of gene-specific transcription from RNA polymerase II promoter, transcription, cell fate commitment, erythrocyte differentiation, positive regulation of erythrocyte differentiation, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	172	TTNNRVKRRPSPYEMEITDGP	PKA_group	9111058	LTP	0.54		-	-	0.77	-	high

Substrate:

tau (Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau))

Seq-ID:

P10636 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-49642   AATF_HUMAN
MINT-74874   KS6B1_HUMAN
MINT-3390085   KC1D_RAT
MINT-3974182   CDK5_HUMAN
MINT-3974216   GSK3B_HUMAN
MINT-7148384   EAA2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
apolipoprotein E binding, SH3 domain binding, lipoprotein binding, identical protein binding, structural constituent of cytoskeleton, enzyme binding, microtubule binding	plasma membrane, cytosol, microtubule associated complex, tubulin complex, axon, growth cone, microtubule	positive regulation of microtubule polymerization, superior temporal gyrus development, negative regulation of microtubule depolymerization, positive regulation of axon extension, microtubule cytoskeleton organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	531	GTPGSRSRTPSLPTPPTREPK	PKA_group	12435421	LTP	0.54		-	-	0.97	-	medium

Substrate:

TBXA2R (receptor activity, rhodopsin-like receptor activity)

Seq-ID:

ENSP00000248419 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
guanyl-nucleotide exchange factor activity, thromboxane A2 receptor activity, protein binding	integral to plasma membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	330	QPRLSTRPRRSLTLWPSLEYS	PKA_group	12147288	LTP	0.26	MOD_PKA_2	-	-	0.27	-	low

Substrate:

Thimet oligopeptidase 1 (Metallo protease)

Seq-ID:

P52888 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7148420 CALM_RAT
MINT-7148437 CALM_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, metalloendopeptidase activity, protein binding	cytoplasm	proteolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	643	LNSKVGMDYRSCILRPGGSED	PKA_group	10969067	LTP	0.04		-	Peptidase_M3	0.31	2O36	54.92%

Substrate:

Thyroid hormone receptor alpha (thyroid hormone receptor alpha (c-ErbA) (from PhosphoBase))

Seq-ID:

P04625 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, thyroid hormone receptor activity, zinc ion binding, sequence-specific DNA binding transcription factor activity, protein binding, steroid hormone receptor activity	nucleus	transcription, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	28	RWLDGKRKRKSSQCLVKSSMS	PKA_group	2903825	LTP	0.19	MOD_PKA_1	-	-	0.26	-	medium
S	29	WLDGKRKRKSSQCLVKSSMSG	PKA_group	2903825	LTP	0.39	MOD_PKA_1	-	-	0.26	-	medium

Substrate:

Transforming protein RhoA (GTPase)

Seq-ID:

P61586 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-56522   CNKR1_HUMAN
MINT-68456   RHG01_HUMAN
MINT-6743347   VAV_HUMAN
MINT-7301170   RTKN_HUMAN
MINT-7717229   OTUB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, myosin binding, GTP binding	plasma membrane, cytoskeleton	negative regulation of axonogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of stress fiber assembly, Rho protein signal transduction, positive regulation of axonogenesis, positive regulation of neuron differentiation, positive regulation of NF-kappaB import into nucleus, interspecies interaction between organisms

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	188	ALQARRGKKKSGCLVL	PKA_group	12654918	LTP	0.11	MOD_PKA_1	-	-	0.36	1CC0	0.0%

Substrate:

Troponin I, cardiac muscle (troponin I, cardiac muscle (from PhosphoBase))

Seq-ID:

P02646 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

Molecular Function	Cellular Component	Biological Process
actin binding

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	22	RPAPAPVRRRSSANYRAYATE	PKA_group	202250	LTP	0.20	MOD_PKA_1	-	-	0.68	-	medium
S	151	RPTLRLRVRISADAMMQALLG	PKA_group	202250	LTP	1.00	MOD_PKA_2	-	Troponin	0.31	-	medium

Substrate:

Troponin I, cardiac muscle (troponin I, cardiac muscle (from PhosphoBase))

Seq-ID:

P19429 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium-dependent protein binding, troponin T binding, protein kinase binding, protein domain specific binding, troponin C binding, calcium channel inhibitor activity, actin binding	troponin complex	regulation of systemic arterial blood pressure by ischemic conditions, negative regulation of ATPase activity, cellular calcium ion homeostasis, cardiac muscle contraction, vasculogenesis, ventricular cardiac muscle tissue morphogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	23	RPAPAPIRRRSSNYRAYATEP	PKA_group	8543035	LTP	0.19	MOD_PKA_1	-	-	0.71	-	-
S	24	PAPAPIRRRSSNYRAYATEPH	PKA_group	8543035	LTP	0.19	MOD_PKA_1	-	-	0.70	-	-

Substrate:

Troponin I, cardiac muscle (troponin I, cardiac muscle (from PhosphoBase))

Seq-ID:

P48787 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
actin binding		regulation of systemic arterial blood pressure by ischemic conditions, cellular calcium ion homeostasis, vasculogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	23	QPAPAPVRRRSSANYRAYATE	PKA_group	15507454	LTP	0.18	MOD_PKA_1	-	-	0.73	-	-
S	24	PAPAPVRRRSSANYRAYATEP	PKA_group	15507454	LTP	0.18	MOD_PKA_1	-	-	0.72	-	-

Substrate:

Troponin I, fast skeletal muscle (troponin I, fast skeletal muscle (from PhosphoBase))

Seq-ID:

P02643 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
troponin T binding, actin binding

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	20	AITARRQHLKSVMLQIAATEL	PKA_group	4369265	LTP	1.00		-	Troponin	0.45	1A2X	59.84%
S	118	KRPPLRRVRMSADAMLKALLG	PKA_group	4369265	LTP	1.00	MOD_PKA_2	-	Troponin	0.47	-	-

Substrate:

Tryptophan 5-hydroxylase 1 (Enzyme: Oxygenase)

Seq-ID:

P09810 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
iron ion binding, amino acid binding, tryptophan 5-monooxygenase activity	cytoplasm, neuron projection	oxidation reduction, response to stress, serotonin biosynthetic process from tryptophan

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	58	IESRKSKRRNSEFEIFVDCDI	PKA_group	9109552	LTP	0.25	MOD_PKA_1	-	ACT	0.26	-	medium

Substrate:

Tryptophan 5-hydroxylase 1 (Enzyme: Oxygenase)

Seq-ID:

P17752 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
iron ion binding, amino acid binding, tryptophan 5-monooxygenase activity	cytosol	oxidation reduction, aromatic amino acid family metabolic process, serotonin biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	58	IESRKSKRRNSEFEIFVDCDI	PKA_group	9109552	LTP	0.21	MOD_PKA_1	-	ACT	0.26	-	low

Substrate:

Tumor necrosis factor receptor superfamily member 16 (Cell surface receptor)

Seq-ID:

P08138 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7012345 SALL2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	endosome, cytosol, integral to plasma membrane, nucleoplasm	induction of apoptosis by extracellular signals, negative regulation of axonogenesis, apoptosis, anti-apoptosis, membrane protein intracellular domain proteolysis, positive regulation of axonogenesis, negative regulation of cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	303	TPPPEGEKLHSDSGISVDSQS	PKA_group	12682012	LTP	1.00		-	-	0.79	-	low

Substrate:

Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))

Seq-ID:

P04177 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amino acid binding, tyrosine 3-monooxygenase activity, ferrous iron binding, ferric iron binding, dopamine binding	mitochondrion, cytosol, synaptic vesicle, terminal button	neurotransmitter biosynthetic process, oxidation reduction, response to hypoxia, response to steroid hormone stimulus, protein homotetramerization, dopamine biosynthetic process from tyrosine

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	40	TSPRFIGRRQSLIEDARKERE	PKA_group	2874140	LTP	1.00	MOD_PKA_1	-	-	0.52	-	medium
S	153	AALLSSVRRVSDDVRSAREDK	PKA_group	2874140	LTP	0.42	MOD_PKA_1	-	-	0.31	-	medium

Substrate:

Tyr-3-hydroxylase (tyrosine 3-monooxygenase (tyrosine 3-hydroxylase) (TH) (from PhosphoBase))

Seq-ID:

P07101 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
tyrosine 3-monooxygenase activity, protein binding	smooth endoplasmic reticulum, perikaryon, internal side of plasma membrane, cytosol, melanosome membrane, nucleus	synaptic transmission, dopaminergic, embryonic camera-type eye morphogenesis, neurotransmitter biosynthetic process, oxidation reduction, response to hypoxia, heart morphogenesis, learning, eye photoreceptor cell development, regulation of heart contraction, visual perception, norepinephrine biosynthetic process, dopamine biosynthetic process from tyrosine, locomotory behavior, memory, epinephrine biosynthetic process, pigmentation, response to ethanol

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	71	RSPRFIGRRQSLIEDARKERE	PKA_group	1680128	LTP	1.00	MOD_PKA_1	-	-	0.61	-	low

Substrate:

Tyrosine-protein phosphatase, non-receptor type 12 (tyrosine phosphatase)

Seq-ID:

Q05209 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50149   PPIP1_HUMAN
MINT-50152   WASP_HUMAN
MINT-61770   GLHA_HUMAN
MINT-61771   TEX10_HUMAN
MINT-61772   RBM19_HUMAN
MINT-61775   UTRO_HUMAN
MINT-61778   BAT3_HUMAN
MINT-61825   SMAD5_HUMAN
MINT-74936   BCAR1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3 domain binding, non-membrane spanning protein tyrosine phosphatase activity	soluble fraction	protein amino acid dephosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	39	ARDFMRLRRLSTKYRTEKIYP	PKA_group	7909431	LTP	1.00	MOD_PKA_1	-	PTPc	0.22	-	medium
S	39	ARDFMRLRRLSTKYRTEKIYP	PKA_group	7520867	LTP	1.00	MOD_PKA_1	-	PTPc	0.22	-	medium
S	435	QIDKKLERNLSFEIKKVPLQE	PKA_group	7909431	LTP	1.00		-	-	0.55	-	medium
S	435	QIDKKLERNLSFEIKKVPLQE	PKA_group	7520867	LTP	1.00		-	-	0.55	-	medium

Substrate:

Tyrosine-protein phosphatase, non-receptor type 7 (Tyrosine phosphatase)

Seq-ID:

P35236 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein tyrosine phosphatase activity, protein binding		protein amino acid dephosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	44	KHVRLQERRGSNVALMLDVRS	PKA_group	10559944	LTP	1.00	MOD_PKA_1	-	-	0.48	-	-

Substrate:

UNC84B (microtubule binding)

Seq-ID:

Q9UH99 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
lamin binding, microtubule binding	nuclear inner membrane, integral to membrane, endosome membrane, SUN-KASH complex	nuclear envelope organization, nuclear matrix anchoring at nuclear membrane, nuclear migration, cytoskeletal anchoring at nuclear membrane, mitotic spindle organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	12	SRRSQRLTRYSQGDDDGSSSS	PKA_group	12239280	LTP	0.19	MOD_PKA_2	-	-	0.81	-	low
S	54	KRKSSNMKRLSPAPQLGPSSD	PKA_group	12239280	LTP	0.06		-	-	0.81	-	low
S	116	GTGGSESSRASGLVGRKATED	PKA_group	12239280	LTP	0.19	MOD_PKA_2	-	-	0.54	-	low

Substrate:

VASP (vasodilator-stimulated phosphoprotein (vasp) (from PhosphoBase))

Seq-ID:

P50552 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-67510   WWP2_HUMAN
MINT-67637   PLS1_HUMAN
MINT-67679   TRIM9_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3 domain binding, actin binding, profilin binding	focal adhesion, cytosol, lamellipodium membrane, actin cytoskeleton, filopodium membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	157	GPSEHIERRVSNAGGPPAPPA	PKA_group	8182057	LTP	0.76	MOD_PKA_1	-	-	0.96	-	-
S	157	GPSEHIERRVSNAGGPPAPPA	PKA_group	8182057	LTP	0.76	MOD_PKA_1	-	-	0.96	-	-
S	239	AIAGAKLRKVSKQEEASGGPT	PKA_group	8182057	LTP	0.11	MOD_PKA_1	-	-	0.90	-	-
S	239	AIAGAKLRKVSKQEEASGGPT	PKA_group	8182057	LTP	0.11	MOD_PKA_1	-	-	0.90	-	-
T	278	NAMLARRRKATQVGEKTPKDE	PKA_group	8182057	LTP	0.13	MOD_PKA_1	-	-	0.89	-	-
T	278	NAMLARRRKATQVGEKTPKDE	PKA_group	8182057	LTP	0.13	MOD_PKA_1	-	-	0.89	-	-

Substrate:

Vimentin (vimentin (from PhosphoBase))

Seq-ID:

P20152 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-19723 ARRB1_HUMAN
MINT-50699 KPCE_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	cytoplasm, type III intermediate filament, cell leading edge	intermediate filament-based process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	5	MSTRSVSSSSYRRMF	PKA_group	2500966	LTP	0.31		-	-	0.50	-	medium
S	47	TYSLGSALRPSTSRSLYSSSP	PKA_group	2500966	LTP	0.72	MOD_PKA_2	-	Filament_head	0.49	-	medium
S	51	GSALRPSTSRSLYSSSPGGAY	PKA_group	2500966	LTP	0.46		-	Filament_head	0.50	-	medium

Substrate:

vitamin D receptor (Vitamin D receptor)

Seq-ID:

P11473 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
vitamin D3 receptor activity, zinc ion binding, sequence-specific DNA binding transcription factor activity, retinoid X receptor binding, steroid hormone receptor activity		negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription, decidualization, negative regulation of cell proliferation, regulation of calcidiol 1-monooxygenase activity, positive regulation of vitamin D 24-hydroxylase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	182	SRHTPSFSGDSSSSCSDHCIT	PKA_group	15474498	LTP	0.63		-	-	0.54	-	medium

Substrate:

Voltage-dependent L-type calcium channel alpha-1C subunit (dihydropyridine-sensitive L-type, cardiac muscle calcium channel (from PhosphoBase))

Seq-ID:

P15381 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
dihydropyridine-sensitive calcium channel activity, calmodulin binding	voltage-gated calcium channel complex, postsynaptic density	elevation of cytosolic calcium ion concentration

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1627	AIIKKIWKRTSMKLLDQVVPP	PKA_group	8664319	LTP	1.00	MOD_PKA_1	-	-	0.18	-	medium
S	1700	DIGPEIRRAISGDLTAEEELD	PKA_group	8664319	LTP	1.00		-	-	0.50	-	medium

Substrate:

Voltage-dependent L-type calcium channel alpha-1S subunit (dihydropyridine-sensitive L-type, skeletal muscle calcium channel (from PhosphoBase))

Seq-ID:

P07293 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
voltage-gated calcium channel activity	voltage-gated calcium channel complex

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	687	KAEERKRRKMSRGLPDKTEEE	PKA_group	2844809	LTP	0.33	MOD_PKA_1	-	-	0.73	-	medium
S	1617	QVDTFLERTNSLPPVMANQRP	PKA_group	2844809	LTP	0.80		-	-	0.52	-	medium
S	1757	DPPERGQRRTSLTGSLQDEAP	PKA_group	7608207	LTP	0.07	MOD_PKA_1	-	-	0.93	-	medium
S	1772	LQDEAPQRRSSEGSTPRRPAP	PKA_group	1322891	LTP	0.60	MOD_PKA_1	-	-	0.96	-	medium
S	1854	SVPGSLSRRSSLGSLDQVQGS	PKA_group	7608207	LTP	0.09	MOD_PKA_1	-	-	0.67	-	medium

Substrate:

Voltage-dependent L-type calcium channel beta-2 subunit (Voltage gated channel)

Seq-ID:

Q08289 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
voltage-gated calcium channel activity, protein binding	sarcolemma, integral to plasma membrane, voltage-gated calcium channel complex	neuromuscular junction development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	219	GDIVPSSRKSTPPSSAIDIDA	PKA_group	10441130	LTP	0.92	MOD_PKA_2	-	-	0.58	-	medium
S	514	TDRSAPIRSASQAEEEPSVEP	PKA_group	10441130	LTP	0.55		-	-	0.90	-	medium
S	514	TDRSAPIRSASQAEEEPSVEP	PKA_group	10567342	LTP	0.55		-	-	0.90	-	medium
S	533	EPVKKSQHRSSSSAPHHNHRS	PKA_group	10441130	LTP	0.48	MOD_PKA_2	-	-	0.94	-	medium
S	533	EPVKKSQHRSSSSAPHHNHRS	PKA_group	10567342	LTP	0.48	MOD_PKA_2	-	-	0.94	-	medium
S	534	PVKKSQHRSSSSAPHHNHRSG	PKA_group	10441130	LTP	0.83	MOD_PKA_2	-	-	0.94	-	medium
S	534	PVKKSQHRSSSSAPHHNHRSG	PKA_group	10567342	LTP	0.83	MOD_PKA_2	-	-	0.94	-	medium

Substrate:

Wilm tumor protein (Transcription regulatory protein)

Seq-ID:

P19544 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, specific transcriptional repressor activity, transcription activator activity, RNA binding, zinc ion binding, promoter binding, sequence-specific DNA binding transcription factor activity, C2H2 zinc finger domain binding	cytoplasm, nuclear speck, nucleoplasm	branching involved in ureteric bud morphogenesis, negative regulation of apoptosis, transcription, glomerular basement membrane development, male gonad development, negative regulation of cell proliferation, sex determination, negative regulation of cell growth, metanephric S-shaped body morphogenesis, glomerular visceral epithelial cell differentiation, positive regulation of gene-specific transcription, negative regulation of translation, adrenal gland development, visceral serous pericardium development, induction of apoptosis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of gene-specific transcription

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	365	CDFKDCERRFSRSDQLKRHQR	PKA_group	11237525	LTP	1.00	MOD_PKA_1	-	ZnF_C2H2	0.44	-	-
S	393	FQCKTCQRKFSRSDHLKTHTR	PKA_group	11237525	LTP	1.00	MOD_PKA_1	-	ZnF_C2H2	0.44	-	-