Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

14-3-3 zeta/delta
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
6-phosphofructokinase, liver type
6-phosphofructokinase, muscle type
A-kinase anchoring protein.
Acetyl-CoA carboxylase 1
Acetylcholine receptor protein, delta chain
ADR1
Alpha adducin
APC
Aquaporin 0
Aquaporin 2
Arachidonate 5 lipoxygenase
ATP-binding cassette 1
ATP-citrate synthase
Aurora kinase A
Aurora-C
B-Raf
BAD
Beta adducin
Beta casein precursor
Beta-2 adrenergic receptor
Beta-ARK-1
Brain sodium channel 2
C/EBP beta
CAD
Calcium/calmodulin-dependent protein kinase kinase 1
cAMP-dependent protein kinase regulatory subunit
cAMP-dependent protein kinase type II-alpha regulatory subunit
cAMP-dependent protein kinase type II-beta regulatory subunit
cAMP-dependent protein kinase, alpha-catalytic subunit
CAPN2
Casein kinase I, delta isoform
CD243
CD42C
CD91
Centrin 1
CETN2
CFTR
Chorionic gonadotrophin beta subunit
Common beta c subunit
Connexin 32
CPI-17
CTP synthase
Cullin 5
Cut like 1
Cyclic-AMP-dependent transcription factor ATF-2
Cyclin D1
Cytochrome P450 2B1
Cytochrome P450 2B2
DARPP-32
Dematin
Desmin
Desmoplakin
DPDE4
Drp1
E3 ubiquitin-protein ligase Nedd-4-like protein
eIF-2-beta
Erythrocyte band 7 integral membrane protein
Erythrocyte membrane protein band 4.2
Estrogen receptor alpha
ETV5
FGF2
Fibrinogen alpha chain
Fructose-1,6-bisphosphatase
G alpha 13
GABA(A) receptor B1
GFAP
GFPT2
Glucosamine--fructose-6-phosphate aminotransferase
GluR-1
GluR-4
GluR-6
Glycogenin-1
GMF-beta
GRK7
GSK-3 alpha
GSK-3 beta
HAND1
HDAC8
Histone H1.1
Histone H2A.c/d/i/n/p
Histone H2B.a/g/h/k/l
HLA-A1
HMG14
hnRPA1
hnRPD
HRH1
HSP27
Inositol 1,4,5-trisphosphate receptor type 1
Integrin alpha 4
IPP1
L-plastin
Lamin Dm0
LASP1
Lipase hormone sensitive
Lipocortin I (annexinI)
Lysozyme C
MBP
Melanocortin 4 receptor
Merlin
MHC class II transactivator
MLCK
Moesin
Mybpc3
MYOM1
Neurabin II protein
Neutrophil cytosol factor 1
NF-ATc1
NFE2L1
NIPP1
Nitric-oxide synthase, brain
Nitric-oxide synthase, endothelial
Nopp140
NPR-A
Nuclear factor NF-kappa-B p105 subunit
Octamer binding transcription factor 1
Orphan nuclear receptor NR4A1
PCTAIRE1
Perilipin
Phenylalanine-4-hydroxylase
Phosducin
Phosphodiesterase 3B
Phosphodiesterase 5A
Phospholamban
Phospholemman precursor
Phosphorylase b kinase alpha regulatory chain, skeletal muscle isoform
Phosphorylase b kinase beta regulatory chain
Phytochrome A type 3
PIN1
PLC beta 3
PLC gamma 1
PMCA1
Potassium voltage-gated channel subfamily H member 2
PPP1R14D
Presenilin 1
Prostaglandin E2 receptor, EP4 subtype
Protamine YI
Protamine YII
Protamine Z
Protein phosphatase 1, regulatory subunit 3A
PTBP1
PTH/PTHr receptor
Pyruvate kinase, isozymes R/L
Raf1
Rap1GAP
Ras related protein 1A
Ras-related protein Rap-1b
Regulator of G-protein signaling 10, isoform a
REL
RGS14
Rho guanine nucleotide exchange factor 7
Rhodopsin kinase
Ryanodine receptor 1
Ryanodine receptor 2
S-protein
Serine/threonine-protein kinase Sgk1
Serotonin acetylase
SNARE-associated protein Snapin
Sodium bicarbonate cotransporter
Sodium channel protein
Sodium channel protein type II alpha subunit
Solute carrier family,member 2
SOX9
spdya-A
Src
Stathmin
STK24
Sucrase isomaltase
Synapsin II
Synapsin-1
TAL-1 protein
tau
TBXA2R
Thimet oligopeptidase 1
Thyroid hormone receptor alpha
Transforming protein RhoA
Troponin I, cardiac muscle
Troponin I, fast skeletal muscle
Tryptophan 5-hydroxylase 1
Tumor necrosis factor receptor superfamily member 16
Tyr-3-hydroxylase
Tyrosine-protein phosphatase, non-receptor type 12
Tyrosine-protein phosphatase, non-receptor type 7
UNC84B
VASP
Vimentin
vitamin D receptor
Voltage-dependent L-type calcium channel alpha-1C subunit
Voltage-dependent L-type calcium channel alpha-1S subunit
Voltage-dependent L-type calcium channel beta-2 subunit
Wilm tumor protein

Substrate:

14-3-3 zeta/delta (14-3-3 protein zeta/delta (Protein kinase C inhibitor protein-1) (KCIP-1) (Factor activating exoenzyme S) (FAS))

Seq-ID:

P63104 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14323   FOXO3_HUMAN
MINT-14772   PRLR_HUMAN
MINT-17015   IL9R_HUMAN
MINT-17278   KC1A_HUMAN
MINT-17367   TPD53_HUMAN
MINT-17571   RIN1_HUMAN
MINT-17818   ATX1_HUMAN
MINT-19329   MPIP2_HUMAN
MINT-19336   ADA23_HUMAN
MINT-45800   RAF1_HUMAN
MINT-48206   NEMO_HUMAN
MINT-48480   M3K3_HUMAN
MINT-50358   HSP71_HUMAN
MINT-50935   EGFR_HUMAN
MINT-51005   IF4A3_HUMAN
MINT-51010   TRA2B_HUMAN
MINT-51012   DFFA_HUMAN
MINT-51013   STK38_HUMAN
MINT-51018   E41L3_HUMAN
MINT-51019   MEP50_HUMAN
MINT-51020   RO52_HUMAN
MINT-51021   TBB5_HUMAN
MINT-51022   ZO2_HUMAN
MINT-51025   KLC4_HUMAN
MINT-51027   Q8IXP7_HUMAN
MINT-51051   K1C19_HUMAN
MINT-51052   K1C18_HUMAN
MINT-63980   KU70_HUMAN
MINT-74924   KAPCA_HUMAN
MINT-74925   P53_HUMAN
MINT-3294407   MPIP1_HUMAN
MINT-3294433   MPIP3_HUMAN
MINT-3294883   MARK2_HUMAN
MINT-3295089   NUMA1_HUMAN
MINT-3295217   PCM1_HUMAN
MINT-3295255   NDE1_HUMAN
MINT-3295375   WEE1_HUMAN
MINT-3295392   CDK18_HUMAN
MINT-3295415   CDK17_HUMAN
MINT-3295530   MARK3_HUMAN
MINT-3295552   BRAF_HUMAN
MINT-3295573   MPRIP_HUMAN
MINT-3295597   ARHG2_HUMAN
MINT-3295618   RHG21_HUMAN
MINT-3295674   GAPD1_HUMAN
MINT-3295696   ARHGG_HUMAN
MINT-3295740   ATLA2_HUMAN
MINT-3295774   LIPB1_HUMAN
MINT-3295882   IRS2_HUMAN
MINT-3295899   PDE3A_HUMAN
MINT-3295953   LIMA1_HUMAN
MINT-3295975   CALM_HUMAN
MINT-3295996   PARD3_HUMAN
MINT-3296030   SI1L3_HUMAN
MINT-3296068   APC_HUMAN
MINT-3296095   NOLC1_HUMAN
MINT-3296132   NUCL_HUMAN
MINT-3296152   NPM_HUMAN
MINT-3296187   PSMD2_HUMAN
MINT-3296221   THIO_HUMAN
MINT-3296237   PRDX1_HUMAN
MINT-3296270   CE170_HUMAN
MINT-3296359   PYRG1_HUMAN
MINT-3296408   NADK_HUMAN
MINT-3296440   NDKB_HUMAN
MINT-3296457   KITH_HUMAN
MINT-3296491   HDAC4_HUMAN
MINT-3296507   HDAC7_HUMAN
MINT-3296523   YBOX1_HUMAN
MINT-3296639   HAT1_HUMAN
MINT-3296655   H4_HUMAN
MINT-3296701   H2A1_HUMAN
MINT-3296729   SPT6H_HUMAN
MINT-3296749   DNMT1_HUMAN
MINT-3296781   RUVB2_HUMAN
MINT-3296831   HNRPF_HUMAN
MINT-3296856   HNRH2_HUMAN
MINT-3296872   HNRPK_HUMAN
MINT-3296888   PCBP1_HUMAN
MINT-3296904   HNRPC_HUMAN
MINT-3296922   ROA1_HUMAN
MINT-3296956   DDX1_HUMAN
MINT-3296972   DDX3X_HUMAN
MINT-3297068   LA_HUMAN
MINT-3297088   RS3_HUMAN
MINT-3297112   RLA0_HUMAN
MINT-3297147   RL19_HUMAN
MINT-3297169   RL5_HUMAN
MINT-3297185   RLA2_HUMAN
MINT-3297202   RS7_HUMAN
MINT-3297276   SYEP_HUMAN
MINT-3297301   PABP2_HUMAN
MINT-3297322   PABP4_HUMAN
MINT-3297360   GCN1L_HUMAN
MINT-3297377   IF4G1_HUMAN
MINT-3297431   EIF3F_HUMAN
MINT-3297456   EF2_HUMAN
MINT-3297472   EF1A1_HUMAN
MINT-3297494   EF1B_HUMAN
MINT-3297642   KINH_HUMAN
MINT-3297660   KLC2_HUMAN
MINT-3297714   DYHC1_HUMAN
MINT-3297730   TBA1B_HUMAN
MINT-3297793   VIME_HUMAN
MINT-3297814   LMNA_HUMAN
MINT-3297843   LMNB1_HUMAN
MINT-3297866   ANXA2_HUMAN
MINT-3297886   ANXA1_HUMAN
MINT-3297917   ACTB_HUMAN
MINT-3297984   TLN1_HUMAN
MINT-3298006   FSCN1_HUMAN
MINT-3298028   HAKAI_HUMAN
MINT-3298189   PROF1_HUMAN
MINT-3298215   COF1_HUMAN
MINT-3304213   K6PP_HUMAN
MINT-3304235   F262_HUMAN
MINT-3304340   FAS_HUMAN
MINT-3304385   ACSL4_HUMAN
MINT-3304469   G3P_HUMAN
MINT-3304487   KCRU_HUMAN
MINT-3304522   LDHB_HUMAN
MINT-3304540   LDHA_HUMAN
MINT-3304560   SPRE_HUMAN
MINT-3304637   KPYM_HUMAN
MINT-3304676   TKT_HUMAN
MINT-3304695   ALDOA_HUMAN
MINT-3304712   ENOA_HUMAN
MINT-3304765   TPIS_HUMAN
MINT-3304790   TCPQ_HUMAN
MINT-3304899   TCPA_HUMAN
MINT-3305086   CH60_HUMAN
MINT-3305120   GRP78_HUMAN
MINT-3305183   HS90A_HUMAN
MINT-3305276   HS105_HUMAN
MINT-3305331   HSPB1_HUMAN
MINT-3305423   PPIA_HUMAN
MINT-3305616   TRAP1_HUMAN
MINT-3305679   HS71L_HUMAN
MINT-3305799   IPO7_HUMAN
MINT-3305862   IMB1_HUMAN
MINT-3306240   TIF1B_HUMAN
MINT-3306314   CIC_HUMAN
MINT-3306548   LMO7_HUMAN
MINT-3306606   VIR_HUMAN
MINT-3306625   FL2D_HUMAN
MINT-3306813   ZC3HD_HUMAN
MINT-3307270   PERQ2_HUMAN
MINT-3307331   LARP1_HUMAN
MINT-3307383   FNBP2_HUMAN
MINT-3307403   SMAG2_HUMAN
MINT-3307456   TERA_HUMAN
MINT-3307546   TPD52_HUMAN
MINT-3307735   MYCB2_HUMAN
MINT-3307756   MCM3_HUMAN
MINT-3307783   ASPP2_HUMAN
MINT-3307813   P3C2B_HUMAN
MINT-3307838   FRAP_HUMAN
MINT-3308034   PAK4_HUMAN
MINT-3308059   RPGF2_HUMAN
MINT-3308248   IQGA1_HUMAN
MINT-3308267   RPGP1_HUMAN
MINT-3308328   ATLA3_HUMAN
MINT-3308436   SRGP1_HUMAN
MINT-3308521   AFAD_HUMAN
MINT-3308685   LIPB1_HUMAN
MINT-3317863   TSC2_HUMAN
MINT-3317888   AKTS1_HUMAN
MINT-3317913   PTN3_HUMAN
MINT-3317930   YAP1_HUMAN
MINT-3317972   SH3B4_HUMAN
MINT-3317988   PSMD1_HUMAN
MINT-3318133   UBP8_HUMAN
MINT-3318149   CAND1_HUMAN
MINT-3318217   UBA1_HUMAN
MINT-3318321   PYR1_HUMAN
MINT-3318337   HDAC5_HUMAN
MINT-3318368   PRI2_HUMAN
MINT-3318428   PTBP1_HUMAN
MINT-3318458   HNRPU_HUMAN
MINT-3318488   DCP1A_HUMAN
MINT-3318520   DHX9_HUMAN
MINT-3318572   SRRM2_HUMAN
MINT-3318588   SYVC_HUMAN
MINT-3318610   SYIC_HUMAN
MINT-3318644   SYAC_HUMAN
MINT-3318676   EIF3A_HUMAN
MINT-3318692   IF4A1_HUMAN
MINT-3318708   KIF23_HUMAN
MINT-3318724   KLC3_HUMAN
MINT-3318808   FLNA_HUMAN
MINT-3318838   CING_HUMAN
MINT-3318854   AHNK_HUMAN
MINT-3318871   DESP_HUMAN
MINT-3318887   EZRI_HUMAN
MINT-3318904   SPTA2_HUMAN
MINT-3318920   SPTB2_HUMAN
MINT-3318937   VINC_HUMAN
MINT-3318960   ACTN4_HUMAN
MINT-3318976   PGAM1_HUMAN
MINT-3319004   PGK1_HUMAN
MINT-3319021   S27A2_HUMAN
MINT-3319127   PANK2_HUMAN
MINT-3319198   PURA1_HUMAN
MINT-3319239   CGL_HUMAN
MINT-3319281   TFR1_HUMAN
MINT-3319320   GRP75_HUMAN
MINT-3319337   HSP7C_HUMAN
MINT-3319393   FKBP4_HUMAN
MINT-3319394   HSP74_HUMAN
MINT-3319575   HS90B_HUMAN
MINT-3319592   XPO1_HUMAN
MINT-3319626   NFAC1_HUMAN
MINT-3319708   NUFP1_HUMAN
MINT-3319791   SET_HUMAN
MINT-3319822   CV028_HUMAN
MINT-3319865   TBCD4_HUMAN
MINT-3319899   KIBRA_HUMAN
MINT-3319917   RAI14_HUMAN
MINT-3319945   MVP_HUMAN
MINT-3319979   1433S_HUMAN
MINT-3319998   ESYT1_HUMAN
MINT-3320046   EDC3_HUMAN
MINT-3320063   MYCPP_HUMAN
MINT-3320079   CLH1_HUMAN
MINT-3320095   MYOF_HUMAN
MINT-3320159   SCAM2_HUMAN
MINT-7262288   KPCE_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein domain specific binding, transcription factor binding	melanosome	anti-apoptosis, signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	58	YKNVVGARRSSWRVVSSIEQK	PKA_group	16376338	LTP	-	MOD_PKA_1	-	14_3_3	0.30	2O02	45.90%

Substrate:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, (from PhosphoBase))

Seq-ID:

P07953 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
6-phosphofructo-2-kinase activity, fructose-2,6-bisphosphate 2-phosphatase activity, identical protein binding, ATP binding, kinase binding, fructose-6-phosphate binding	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex	fructose 2,6-bisphosphate metabolic process, response to cAMP, positive regulation of glucokinase activity, organ regeneration, response to insulin stimulus, response to glucagon stimulus, response to glucocorticoid stimulus, response to starvation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	33	SSSVLQRRRGSSIPQFTNSPT	PKA_group	6330071	LTP	0.44	MOD_PKA_1	-	6PF2K	0.49	-	low

Substrate:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Enzyme: Phosphotransferase)

Seq-ID:

P26285 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
6-phosphofructo-2-kinase activity, fructose-2,6-bisphosphate 2-phosphatase activity, ATP binding		fructose 2,6-bisphosphate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	467	SQTPVRMRRNSFTPLSSSNTI	PKA_group	2846551	LTP	0.61	MOD_PKA_1	-	-	0.68	-	low

Substrate:

6-phosphofructokinase, liver type (6-phosphofructokinase, liver type (from PhosphoBase))

Seq-ID:

P17858 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48115   IKKE_HUMAN
MINT-48463   M3K3_HUMAN
MINT-49011   RELB_HUMAN
MINT-49206   TAB2_HUMAN
MINT-61849   PR40A_HUMAN
MINT-2861721   ATN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
identical protein binding, metal ion binding, ATP binding, kinase binding, fructose-6-phosphate binding, 6-phosphofructokinase activity	6-phosphofructokinase complex	fructose 6-phosphate metabolic process, protein oligomerization, glycolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	773	SGELEHVTRRTLSMDKGF	PKA_group	8670219	LTP	0.15	MOD_PKA_2	-	-	0.27	-	medium

Substrate:

6-phosphofructokinase, muscle type (6-phosphofructokinase, muscle type (from PhosphoBase))

Seq-ID:

P00511 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein C-terminus binding, metal ion binding, ATP binding, 6-phosphofructokinase activity	6-phosphofructokinase complex	glycolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	377	FDEAMKLRGRSFMNNWEVYKL	PKA_group	1825608	LTP	0.98		-	-	0.18	-	medium
S	775	AHLEHISRKRSGEATV	PKA_group	1825608	LTP	0.22	MOD_PKA_1	-	-	0.50	-	medium

Substrate:

A-kinase anchoring protein. (kinase activity, Rho guanyl-nucleotide exchange factor activity)

Seq-ID:

Q12802 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Rho guanyl-nucleotide exchange factor activity, cAMP-dependent protein kinase activity, metal ion binding, signal transducer activity, protein binding	membrane fraction, cytosol, nucleus, membrane	induction of apoptosis by extracellular signals, apoptosis, regulation of Rho protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1565	MRSLSPFRRHSWGPGKNAASD	PKA_group	15229649	LTP	-	MOD_PKA_1	-	-	0.66	-	medium
S	2733	SELSVSPKRNSISRTHKDKGP	PKA_group	15383279	LTP	-	MOD_PKA_1	-	-	0.79	-	medium

Substrate:

Acetyl-CoA carboxylase 1 (Enzyme: Carboxylase)

Seq-ID:

P11497 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, acetyl-CoA carboxylase activity, biotin carboxylase activity, ATP binding, biotin binding	soluble fraction	response to organic cyclic substance, acetyl-CoA metabolic process, response to drug, fatty acid biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	77	QDGLAFHMRSSMSGLHLVKQG	PKA_group	2900138	LTP	0.16	MOD_PKA_2	-	-	0.30	-	low
S	1200	RGNIPTLNRMSFASNLNHYGM	PKA_group	7915280	LTP	0.83	MOD_PKA_2	-	ACC_central	0.27	-	low
S	1200	RGNIPTLNRMSFASNLNHYGM	PKA_group	2900138	LTP	0.83	MOD_PKA_2	-	ACC_central	0.27	-	low

Substrate:

Acetylcholine receptor protein, delta chain (Acetylcholine receptor)

Seq-ID:

P02718 [Torpedo californica]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nicotinic acetylcholine-activated cation-selective channel activity, receptor activity	cell junction, integral to membrane, postsynaptic membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	381	DWQNDLKLRRSSSVGYISKAQ	PKA_group	3038884	LTP	0.23	MOD_PKA_1	-	Neur_chan_memb	0.25	-	medium
S	382	WQNDLKLRRSSSVGYISKAQE	PKA_group	3038884	LTP	1.00	MOD_PKA_1	-	Neur_chan_memb	0.22	-	medium
S	383	QNDLKLRRSSSVGYISKAQEY	PKA_group	3038884	LTP	1.00	MOD_PKA_1	-	Neur_chan_memb	0.19	-	medium

Substrate:

ADR1 (regulatory protein ADR1 (from PhosphoBase))

Seq-ID:

P07248 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7929868 FUS3_YEAST

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	transcription, peroxisome organization, regulation of carbohydrate metabolic process, negative regulation of transcription from RNA polymerase II promoter by glucose

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	230	KYLKKLTRRASFSAQSASSYA	PKA_group	2644045	LTP	1.00	MOD_PKA_1	-	-	0.41	-	low
S	230	KYLKKLTRRASFSAQSASSYA	PKA_group	8910470	LTP	1.00	MOD_PKA_1	-	-	0.41	-	low

Substrate:

Alpha adducin (Structural protein)

Seq-ID:

P35611 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-72730 RFX1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
spectrin binding, protein heterodimerization activity, protein homodimerization activity, metal ion binding, transcription factor binding, calmodulin binding, actin filament binding	plasma membrane, cytosol, F-actin capping protein complex, nucleus	positive regulation of protein binding, actin filament bundle assembly, barbed-end actin filament capping

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	59	FNMMEQKKRVSMILQSPAFCE	PKA_group	8810272	LTP	1.00	MOD_PKA_1	-	-	0.35	-	medium
S	408	PALREKSKKYSDVEVPASVTG	PKA_group	8810272	LTP	1.00	MOD_PKA_1	-	-	0.46	-	medium
S	436	DSGTCSPLRHSFQKQQREKTR	PKA_group	8810272	LTP	0.10	MOD_PKA_2	-	-	0.65	-	medium
S	481	KWTKEDGHRTSTSAVPNLFVP	PKA_group	8810272	LTP	0.67	MOD_PKA_2	-	-	0.61	-	medium

Substrate:

APC (Adhesion molecule)

Seq-ID:

P25054 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1780719   DLG4_MOUSE
MINT-3296068   1433Z_HUMAN
MINT-3975353   1433S_HUMAN
MINT-4508229   CTNB1_HUMAN
MINT-6732416   SCRIB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
microtubule plus-end binding, protein kinase regulator activity, protein kinase binding, beta-catenin binding, gamma-catenin binding	centrosome, Axin-APC-beta-catenin-GSK3B complex, beta-catenin destruction complex, cytosol, lateral plasma membrane, kinetochore, adherens junction, nucleus, tight junction	negative regulation of cyclin-dependent protein kinase activity, positive regulation of protein catabolic process, protein complex assembly, positive regulation of cell migration, positive regulation of pseudopodium assembly, cell cycle arrest, cytokinesis after mitosis, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of apoptosis, canonical Wnt receptor signaling pathway, negative regulation of microtubule depolymerization, regulation of attachment of spindle microtubules to kinetochore, response to DNA damage stimulus, cell adhesion, tight junction assembly, mitotic cell cycle spindle assembly checkpoint

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2054	SSAMPKKKKPSRLKGDNEKHS	PKA_group	11050185	LTP	0.11	MOD_PKA_1	-	-	0.81	-	medium

Substrate:

Aquaporin 0 (Water channel. Transporter activity)

Seq-ID:

P06624 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of eye lens	gap junction, integral to membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	243	RLSILKGSRPSESNGQPEVTG	PKA_group	2176601	LTP	0.36	MOD_PKA_2	-	-	0.55	-	-

Substrate:

Aquaporin 0 (Water channel. Transporter activity)

Seq-ID:

P30301 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of eye lens	gap junction, integral to plasma membrane	visual perception, response to stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	229	YDFLLFPRLKSISERLSVLKG	PKA_group	2176601	LTP	0.27		-	-	0.03	-	medium
S	231	FLLFPRLKSISERLSVLKGAK	PKA_group	2176601	LTP	0.96		-	-	0.06	-	medium

Substrate:

Aquaporin 2 (Water channel)

Seq-ID:

P41181 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
glycerol transmembrane transporter activity, water channel activity	integral to membrane, cytoplasmic vesicle membrane, apical plasma membrane	excretion, cellular response to copper ion, cellular response to mercury ion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	256	WEEREVRRRQSVELHSPQSLP	PKA_group	10710543	LTP	0.37	MOD_PKA_1	-	-	0.54	-	medium

Substrate:

Arachidonate 5 lipoxygenase (Enzyme: Lipase)

Seq-ID:

P09917 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
arachidonate 5-lipoxygenase activity, iron ion binding, lipoxygenase activity, protein binding	nuclear envelope lumen, cytosol, nuclear membrane, nuclear matrix	oxidation reduction, leukotriene biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	272	MVECSLERQLSLEQEVQQGNI	PKA_group	11844797	LTP	0.64		-	Lipoxygenase	0.18	-	high
S	524	YVYGMRGRKSSGFPKSVKSRE	PKA_group	16230355	LTP	0.90	MOD_PKA_1	-	Lipoxygenase	0.32	-	high
S	524	YVYGMRGRKSSGFPKSVKSRE	PKA_group	15280375	LTP	0.90	MOD_PKA_1	-	Lipoxygenase	0.32	-	high

Substrate:

ATP-binding cassette 1 (Transport/cargo protein)

Seq-ID:

O95477 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-59503 SNTB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATPase activity, anion transmembrane transporter activity, apolipoprotein A-I receptor activity, small GTPase binding, cholesterol binding, phospholipid binding, ATP binding, phospholipid transporter activity, syntaxin-13 binding, cholesterol transporter activity	membrane fraction, integral to plasma membrane, phagocytic vesicle, membrane raft	positive regulation of cAMP biosynthetic process, platelet dense granule organization, high-density lipoprotein particle assembly, cholesterol homeostasis, endosome transport, phospholipid homeostasis, lysosome organization, negative regulation of macrophage derived foam cell differentiation, phospholipid efflux, negative regulation of cholesterol storage, reverse cholesterol transport, Cdc42 protein signal transduction, cholesterol efflux, cholesterol metabolic process, interleukin-1 beta secretion, intracellular cholesterol transport, G-protein coupled receptor protein signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1042	QLSGGMQRKLSVALAFVGGSK	PKA_group	12196520	LTP	1.00	MOD_PKA_1	-	AAA	0.13	-	medium
S	2054	NYSGGNKRKLSTAMALIGGPP	PKA_group	12196520	LTP	1.00	MOD_PKA_1	-	AAA	0.29	-	medium

Substrate:

ATP-citrate synthase (ATPase)

Seq-ID:

P16638 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP citrate synthase activity, metal ion binding, ATP binding, succinate-CoA ligase (ADP-forming) activity	cytoplasm, soluble fraction	fatty acid biosynthetic process, acetyl-CoA biosynthetic process, citrate metabolic process, cellular carbohydrate metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	454	TSTPAPSRTASFSESRADEVA	PKA_group	6286669	LTP	0.68		-	-	0.72	-	low

Substrate:

ATP-citrate synthase (ATPase)

Seq-ID:

P53396 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP citrate synthase activity, metal ion binding, ATP binding, succinate-CoA ligase (ADP-forming) activity, citrate (pro-3S)-lyase activity, protein binding	cytosol, citrate lyase complex	coenzyme A metabolic process, ATP catabolic process, citrate metabolic process, cellular carbohydrate metabolic process, lipid biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	455	TSTPAPSRTASFSESRADEVA	PKA_group	10653665	LTP	0.68		-	-	0.73	-	medium

Substrate:

Aurora kinase A (Serine/threonine kinase)

Seq-ID:

O14965 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, protein kinase binding, ATP binding	spindle microtubule, nucleus, spindle pole centrosome	protein amino acid phosphorylation, cell division, phosphoinositide-mediated signaling, mitosis, spindle organization, regulation of protein stability

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	288	SVHAPSSRRTTLCGTLDYLPP	PKA_group	11039908	LTP	1.00	MOD_PKA_1	-	S_TKc	0.28	1MQ4	33.56%

Substrate:

Aurora-C (Ser/Thr protein kinase family)

Seq-ID:

O88445 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding	chromosome, centromeric region, cytoplasm, spindle pole	protein amino acid phosphorylation, cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	171	SVHTPSLRRKTMCGTLDYLPP	PKA_group	11879579	LTP	0.97	MOD_PKA_1	-	S_TKc	0.25	-	low
T	175	PSLRRKTMCGTLDYLPPEMIA	PKA_group	11879579	LTP	0.97		-	S_TKc	0.29	-	low

Substrate:

B-Raf (B-Raf proto-oncogene serine/threonine-protein kinase)

Seq-ID:

P15056 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50344   1433B_HUMAN
MINT-50372   1433T_HUMAN
MINT-2833162   KPCA_HUMAN
MINT-2833238   KPCE_HUMAN
MINT-2833314   KS6A2_HUMAN
MINT-3295552   1433Z_HUMAN
MINT-3374124   M3K1_HUMAN
MINT-3975375   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, ATP binding	cytoplasm, nucleus	protein amino acid phosphorylation, organ morphogenesis, anti-apoptosis, small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	429	SPGPQRERKSSSSSEDRNRMK	PKA_group	11510412	LTP	1.00	MOD_PKA_1	-	-	0.92	-	-

Substrate:

BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))

Seq-ID:

Q92934 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14699   B2CL1_HUMAN
MINT-66103   1433S_HUMAN
MINT-7034091   B2L11_HUMAN
MINT-7717137   NAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding	cytosol, mitochondrial outer membrane	induction of apoptosis by extracellular signals, activation of pro-apoptotic gene products

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	75	GAVEIRSRHSSYPAGTEDDEG	PKA_group	15226424	LTP	0.32	MOD_PKA_2	-	Bcl-2_BAD	0.83	-	medium

Substrate:

Beta adducin (Anchor protein)

Seq-ID:

P35612 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
spectrin binding, protein heterodimerization activity, protein homodimerization activity, metal ion binding, calmodulin binding, actin filament binding	plasma membrane, cytoplasm, F-actin capping protein complex	positive regulation of protein binding, actin filament bundle assembly, barbed-end actin filament capping

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	55	FNLMEQKKRVTMILQSPSFRE	PKA_group	8810272	LTP	0.95	MOD_PKA_1	-	-	0.40	-	medium

Substrate:

Beta casein precursor (beta casein (from PhosphoBase))

Seq-ID:

P02666 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
antioxidant activity, transporter activity, metalloendopeptidase inhibitor activity	extracellular region	regulation of blood pressure

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	139	YPVEPFTESQSLTLTDVENLH	PKA_group	1059131	LTP	0.19		-	Casein	0.47	-	low

Substrate:

Beta-2 adrenergic receptor (Protein G coupled receptor)

Seq-ID:

P07550 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1796656   NHRF1_HUMAN
MINT-4051815   SRC_HUMAN
MINT-7291631   UBP33_HUMAN
MINT-7720120   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
potassium channel regulator activity, protein homodimerization activity, norepinephrine binding, beta2-adrenergic receptor activity	receptor complex, endosome, integral to plasma membrane, lysosome	positive regulation of MAPKKK cascade, receptor-mediated endocytosis, activation of transmembrane receptor protein tyrosine kinase activity, endosome to lysosome transport, desensitization of G-protein coupled receptor protein signaling pathway by arrestin

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	262	GRTGHGLRRSSKFCLKEHKAL	PKA_group	11146000	LTP	1.00	MOD_PKA_1	-	7tm_1	0.20	-	-
S	345	AFQELLCLRRSSLKAYGNGYS	PKA_group	11146000	LTP	0.14	MOD_PKA_1	-	-	0.08	2R4R	83.61%
S	346	FQELLCLRRSSLKAYGNGYSS	PKA_group	11146000	LTP	0.18	MOD_PKA_1	-	-	0.10	2R4R	28.69%

Substrate:

Beta-ARK-1 (Beta-adrenergic receptor kinase)

Seq-ID:

P25098 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51490   EGFR_HUMAN
MINT-3376147   MDM2_HUMAN
MINT-6608788   GIT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
G-protein coupled receptor kinase activity, ATP binding, Edg-2 lysophosphatidic acid receptor binding, alpha-2A adrenergic receptor binding, beta-adrenergic receptor kinase activity, signal transducer activity	cytosol, soluble fraction	negative regulation of striated muscle contraction, desensitization of G-protein coupled receptor protein signaling pathway, positive regulation of catecholamine secretion, muscarinic acetylcholine receptor signaling pathway, tachykinin receptor signaling pathway, peptidyl-serine phosphorylation, cardiac muscle contraction, negative regulation of the force of heart contraction by chemical signal

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	685	LSKVPLVQRGSANGL	PKA_group	11278469	LTP	0.26	MOD_PKA_2	-	-	0.36	-	-

Substrate:

Brain sodium channel 2 (Ion channel, other)

Seq-ID:

P78348 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amiloride-sensitive sodium channel activity, protein binding	integral to plasma membrane	response to pH, signal transduction, calcium ion transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	479	GKCQKEAKRSSADKGVALSLD	PKA_group	12578970	LTP	0.41	MOD_PKA_1	-	-	0.33	-	high

Substrate:

C/EBP beta (Transcription factor)

Seq-ID:

P17676 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-14023   SMAD3_HUMAN
MINT-14687   SMAD4_HUMAN
MINT-49733   HMGA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
RNA polymerase II transcription factor activity, enhancer binding		transcription from RNA polymerase II promoter, immune response, acute-phase response

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	288	RERNNIAVRKSRDKAKMRNLE	PKA_group	9374525	LTP	1.00	MOD_PKA_2	-	COIL	0.73	2E42	62.30%

Substrate:

CAD (carbamoyl-phosphate synthase (glutamine-hyd...)

Seq-ID:

P27708 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48168   NEMO_HUMAN
MINT-48300   M3K1_HUMAN
MINT-48426   M3K3_HUMAN
MINT-48660   NFKB1_HUMAN
MINT-48723   NFKB2_HUMAN
MINT-48821   M3K14_HUMAN
MINT-48995   RELB_HUMAN
MINT-49046   RIPK1_HUMAN
MINT-49196   TAB2_HUMAN
MINT-49403   TNR1B_HUMAN
MINT-3318321   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
aspartate carbamoyltransferase activity, dihydroorotase activity, carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, metal ion binding, ATP binding, enzyme binding, protein kinase activity, aspartate binding	cytosol, nuclear matrix	`de novo` pyrimidine base biosynthetic process, protein amino acid autophosphorylation, pyrimidine nucleotide biosynthetic process, peptidyl-threonine phosphorylation, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1406	SMRGAGGRRLSSFVTKGYRTR	PKA_group	17206380	LTP	1.00	MOD_PKA_1	-	MGS	0.28	-	medium
S	1406	SMRGAGGRRLSSFVTKGYRTR	PKA_group	14991569	LTP	1.00	MOD_PKA_1	-	MGS	0.28	-	medium
S	1406	SMRGAGGRRLSSFVTKGYRTR	PKA_group	17485345	LTP	1.00	MOD_PKA_1	-	MGS	0.28	-	medium

Substrate:

Calcium/calmodulin-dependent protein kinase kinase 1 (Ser/Thr protein kinase family)

Seq-ID:

Q8N5S9 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6491300 1433F_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP binding, calmodulin-dependent protein kinase activity, calmodulin binding	cytosol, nucleus	protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	108	HISPRAWRRPTIESHHVAISD	PKA_group	10187789	LTP	1.00	MOD_PKA_1	-	-	0.51	-	medium

Substrate:

cAMP-dependent protein kinase regulatory subunit (cAMP-dependent protein kinase regulatory chain (from PhosphoBase))

Seq-ID:

P07278 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, identical protein binding, cAMP-dependent protein kinase regulator activity, cAMP-dependent protein kinase inhibitor activity	plasma membrane, cAMP-dependent protein kinase complex, cytoplasm, nucleus	negative regulation of Ras protein signal transduction, signal transduction, regulation of protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	145	PMHFNAQRRTSVSGETLQPNN	PKA_group	1956339	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium

Substrate:

cAMP-dependent protein kinase type II-alpha regulatory subunit (cAMP-dependent protein kinase type II-alpha regulatory chain)

Seq-ID:

P00515 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-1779097 CSK21_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	cAMP-dependent protein kinase complex	signal transduction, regulation of protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	96	PIPGRFDRRVSVCAETYNPDE	PKA_group	4367815	LTP	0.96	MOD_PKA_1	-	-	0.52	-	medium

Substrate:

cAMP-dependent protein kinase type II-alpha regulatory subunit (cAMP-dependent protein kinase type II-alpha regulatory chain)

Seq-ID:

P13861 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-2411858   AKA12_HUMAN
MINT-2411925   AKAP1_HUMAN
MINT-2983605   1433S_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	membrane fraction, cytosol	intracellular signaling pathway, signal transduction, activation of protein kinase A activity, regulation of protein amino acid phosphorylation, hormone-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	99	PVPSRFNRRVSVCAETYNPDE	PKA_group	11263724	LTP	0.97	MOD_PKA_1	-	-	0.53	-	low

Substrate:

cAMP-dependent protein kinase type II-beta regulatory subunit (cAMP-dependent protein kinase type II-beta regulatory chain)

Seq-ID:

P31322 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding	cAMP-dependent protein kinase complex	signal transduction, regulation of protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	114	PVINRFTRRASVCAEAYNPDE	PKA_group	4030778	LTP	0.98	MOD_PKA_1	-	-	0.45	-	low

Substrate:

cAMP-dependent protein kinase type II-beta regulatory subunit (cAMP-dependent protein kinase type II-beta regulatory chain)

Seq-ID:

P31323 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP binding, cAMP-dependent protein kinase regulator activity	cytosol	intracellular signaling pathway, signal transduction, activation of protein kinase A activity, regulation of protein amino acid phosphorylation, hormone-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	114	PVINRFTRRASVCAEAYNPDE	PKA_group	7479855	LTP	0.98	MOD_PKA_1	-	-	0.44	-	medium

Substrate:

cAMP-dependent protein kinase, alpha-catalytic subunit (cAMP-dependent protein kinase)

Seq-ID:

P00517 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cAMP-dependent protein kinase activity, ATP binding	neuromuscular junction, nucleus	mesoderm formation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	198	FAKRVKGRTWTLCGTPEYLAP	PKA_group	221492	LTP	0.95		-	S_TKc	0.09	1XH9	48.63%
S	339	DDYEEEEIRVSINEKCGKEFS	PKA_group	6262777	LTP	0.85	MOD_PKA_2	-	S_TK_X	0.30	1XH9	74.59%

Substrate:

CAPN2 (cysteine-type peptidase activity)

Seq-ID:

P17655 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1795337 NMT1_HUMAN
MINT-6793394 PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	plasma membrane, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	369	TKMDGNWRRGSTAGGCRNYPN	PKA_group	11909964	LTP	0.98	MOD_PKA_1	-	calpain_III	0.41	1KFX	7.38%
T	370	KMDGNWRRGSTAGGCRNYPNT	PKA_group	11909964	LTP	1.00	MOD_PKA_1	-	calpain_III	0.41	1KFX	0.00%

Substrate:

Casein kinase I, delta isoform (casein kinase I activity)

Seq-ID:

Q06486 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-3389911   SNAPN_MOUSE
MINT-3390028   P53_HUMAN
MINT-3390055   MAP4_HUMAN
MINT-3390085   TAU_HUMAN
MINT-3390466   MAP1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, peptide binding, glycoprotein binding, ATP binding, phosphoprotein binding	centrosome, spindle, soluble fraction, nucleus	protein amino acid phosphorylation, mitotic cell cycle, regulation of circadian rhythm, circadian regulation of gene expression, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Wnt receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	370	VSGMERERKVSMRLHRGAPVN	PKA_group	17594292	LTP	0.64	MOD_PKA_1	-	-	0.76	-	low

Substrate:

CD243 (multidrug resistance protein 1 (P-glycoprotein 1) (from PhosphoBase))

Seq-ID:

P08183 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-50920 CAV1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
xenobiotic-transporting ATPase activity, ATP binding, protein binding	membrane fraction, cell surface, integral to membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	667	DSRSSLIRKRSTRRSVRGSQA	PKA_group	8132598	LTP	0.92	MOD_PKA_1	-	-	0.51	-	medium
S	683	RGSQAQDRKLSTKEALDESIP	PKA_group	8132598	LTP	0.39	MOD_PKA_1	-	-	0.44	-	medium

Substrate:

CD42C (platelet glycoprotein IB beta chain precursor (GP-IB beta) (from PhosphoBase))

Seq-ID:

P13224 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transmembrane receptor activity, protein binding	integral to plasma membrane, platelet alpha granule membrane	cell surface receptor linked signaling pathway, cell adhesion, platelet activation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	191	RARARAAARLSLTDPLVAERA	PKA_group	2504723	LTP	0.79	MOD_PKA_2	YWHAZ 14-3-3	-	0.22	-	medium

Substrate:

CD91 (Cell surface receptor)

Seq-ID:

Q07954 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, calcium ion binding, lipid transporter activity, lipoprotein binding, lipoprotein receptor binding, apolipoprotein binding, protein complex binding	membrane fraction, integral to plasma membrane, coated pit, nucleus	lipid metabolic process, regulation of phospholipase A2 activity, negative regulation of Wnt receptor signaling pathway, positive regulation of cholesterol efflux, apoptotic cell clearance, multicellular organismal development, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	4517	YATLYMGGHGSRHSLASTDEK	PKA_group	11158305	LTP	0.11	MOD_PKA_2	-	-	0.41	-	low
S	4520	LYMGGHGSRHSLASTDEKREL	PKA_group	12069755	LTP	0.23	MOD_PKA_2	-	-	0.49	-	low

Substrate:

Centrin 1 (Calcium binding protein)

Seq-ID:

Q12798 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, ATP-dependent helicase activity, ATP binding, nucleic acid binding	spindle pole	cell division, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	170	EEFLRIMKKTSLY	PKA_group	11279195	LTP	0.03		-	-	0.18	-	low

Substrate:

CETN2 (calcium ion binding, protein binding)

Seq-ID:

P41208 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, ATP-dependent helicase activity, ATP binding, nucleic acid binding	cytosol, centriole	cell division, centriole replication, regulation of cytokinesis, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	170	QEFLRIMKKTSLY	PKA_group	11279195	LTP	0.05		-	-	0.18	-	-

Substrate:

CFTR (cystic fibrosis transmembrane conductance regulator (CFTR) (from PhosphoBase))

Seq-ID:

P13569 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-60075   NHRF1_MOUSE
MINT-69537   BCR_HUMAN
MINT-73263   NHRF3_MOUSE
MINT-1783772   GOPC_HUMAN
MINT-1787402   NHRF2_HUMAN
MINT-1794992   CALX_HUMAN
MINT-1796681   NHRF1_HUMAN
MINT-7218998   UBP19_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
channel-conductance-controlling ATPase activity, ATP-binding and phosphorylation-dependent chloride channel activity, ATP binding, enzyme binding, PDZ domain binding	early endosome membrane, basolateral plasma membrane, chloride channel complex, apical plasma membrane	respiratory gaseous exchange

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	660	FDQFSAERRNSILTETLHRFS	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.28	2BBS	43.44%
S	700	TGEFGEKRKNSILNPINSIRK	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.41	-	-
S	737	DSDEPLERRLSLVPDSEQGEA	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.64	-	-
S	753	EQGEAILPRISVISTGPTLQA	PKA_group	7530719	LTP	0.34	MOD_PKA_2	-	-	0.48	-	-
S	768	GPTLQARRRQSVLNLMTHSVN	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.46	-	-
S	795	RKTTASTRKVSLAPQANLTEL	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.40	-	-
S	813	TELDIYSRRLSQETGLEISEE	PKA_group	1377674	LTP	1.00	MOD_PKA_1	-	-	0.29	-	-

Substrate:

Chorionic gonadotrophin beta subunit (choriogonatropin beta chain precursor (from PhosphoBase))

Seq-ID:

P01233 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-24926 GLHA_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
hormone activity	extracellular region, soluble fraction	apoptosis, signal transduction, cell-cell signaling, female gamete generation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	86	VCNYRDVRFESIRLPGCPRGV	PKA_group	6196363	LTP	0.16		-	GHB	0.16	1HCN	57.38%
S	116	LSCQCALCRRSTTDCGGPKDH	PKA_group	6196363	LTP	0.22	MOD_PKA_1	-	GHB	0.11	1HCN	78.69%
T	117	SCQCALCRRSTTDCGGPKDHP	PKA_group	6196363	LTP	0.84	MOD_PKA_1	-	GHB	0.12	1HCN	59.59%

Substrate:

Common beta c subunit (Cytokine recpetor common beta chain)

Seq-ID:

P32927 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cytokine receptor activity	granulocyte macrophage colony-stimulating factor receptor complex	respiratory gaseous exchange

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	601	GPYLGPPHSRSLPDILGQPEP	PKA_group	10949031	LTP	1.00		YWHAQ 14-3-3; YWHAZ 14-3-3	-	0.90	-	medium

Substrate:

Connexin 32 (Intercellular channel)

Seq-ID:

P08033 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
gap junction channel activity	connexon complex, integral to membrane, endoplasmic reticulum	protein oligomerization, cell communication, purine ribonucleotide transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	233	RRSNPPSRKGSGFGHRLSPEY	PKA_group	2170122	LTP	0.61	MOD_PKA_1	-	-	0.52	-	medium

Substrate:

Connexin 32 (Intercellular channel)

Seq-ID:

P08034 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
gap junction channel activity	connexon complex, integral to membrane, endoplasmic reticulum membrane	nervous system development, cell-cell signaling

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	233	RRSNPPSRKGSGFGHRLSPEY	PKA_group	8390988	LTP	0.49	MOD_PKA_1	-	-	0.52	-	low

Substrate:

CPI-17 (Inhibitor of PPP1CA)

Seq-ID:

Q96A00 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-16604 KC1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity, protein binding	cytoplasm	regulation of phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	38	GGLQKRHARVTVKYDRRELQR	PKA_group	15003508	LTP	1.00	MOD_PKA_2	-	PP1_inhibitor	0.51	-	medium

Substrate:

CTP synthase (Enzyme: Ligase)

Seq-ID:

P17812 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-3296359 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP binding, CTP synthase activity, protein binding		CTP biosynthetic process, response to drug, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	455	GGTMRLGKRRTLFQTKNSVMR	PKA_group	17189248	LTP	1.00	MOD_PKA_1	-	GATase	0.37	-	medium

Substrate:

Cullin 5 (Ubiquitin proteasome system protein)

Seq-ID:

Q93034 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-61623 SMAD2_HUMAN
MINT-7277713 ELOA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, calcium channel activity, ubiquitin protein ligase binding	cytosol, cullin-RING ubiquitin ligase complex	negative regulation of cell proliferation, cell cycle arrest, G1/S transition of mitotic cell cycle, induction of apoptosis by intracellular signals, interspecies interaction between organisms, ubiquitin-dependent protein catabolic process, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	730	IQIMKMRKKISNAQLQTELVE	PKA_group	10898738	LTP	0.31	MOD_PKA_1	-	Cullin_Nedd8	0.16	3DPL	31.97%

Substrate:

Cut like 1 (Transcription regulatory protein)

Seq-ID:

P39880 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13924   RB_HUMAN
MINT-64663   BIN1_HUMAN
MINT-64665   RECQ5_HUMAN
MINT-64666   RNZ2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity	nucleus	transcription, negative regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1215	EKKAYMKRRHSSVSDSQPCEP	PKA_group	16574653	LTP	1.00	MOD_PKA_1	-	-	0.68	-	medium

Substrate:

Cyclic-AMP-dependent transcription factor ATF-2 (Transcription factor)

Seq-ID:

P15336 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-1788416   JUNB_HUMAN
MINT-6628041   JUN_HUMAN
MINT-6628046   CITE1_HUMAN
MINT-6699865   I2BP1_HUMAN
MINT-7555703   HDAC4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, protein dimerization activity, RNA polymerase II transcription factor activity, transcription coactivator activity, zinc ion binding, sequence-specific DNA binding transcription factor activity	nucleoplasm	transcription, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	44	TLKFGPARNDSVIVADQTPTP	PKA_group	1661585	LTP	0.00		-	-	0.62	-	-
S	44	TLKFGPARNDSVIVADQTPTP	PKA_group	1661585	LTP	0.00		-	-	0.62	-	-

Substrate:

Cyclin D1 (Cyclin D1)

Seq-ID:

P24385 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-50433   CDK4_HUMAN
MINT-50434   CDK6_HUMAN
MINT-50435   MCM10_HUMAN
MINT-50437   CDN1A_HUMAN
MINT-7033534   CDK4_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding	cytosol, cyclin-dependent protein kinase holoenzyme complex, nucleoplasm	positive regulation of protein amino acid phosphorylation, cell division, response to UV-A, mitotic cell cycle G1/S DNA damage checkpoint, G1/S transition of mitotic cell cycle, response to drug, positive regulation of cyclin-dependent protein kinase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	90	LAMNYLDRFLSLEPVKKSRLQ	PKA_group	8058338	LTP	1.00	-	CYCLIN	0.08	2W96	14.75%
S	197	ALCATDVKFISNPPSMVAAGS	PKA_group	8058338	LTP	0.06	-	Cyclin_C	0.16	2W96	57.38%
S	234	LSYYRLTRFLSRVIKCDPDCL	PKA_group	8058338	LTP	0.15	-	Cyclin_C	0.05	2W96	4.10%

Substrate:

Cytochrome P450 2B1 (cytochrome P450 IIB1 (P450-B) (from PhosphoBase))

Seq-ID:

P00176 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
heme binding, electron carrier activity, aromatase activity, steroid hydroxylase activity	microsome, endoplasmic reticulum membrane	response to sulfur dioxide, oxidation reduction, drug metabolic process, response to organic cyclic substance, response to drug, response to calcium ion, response to insulin stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	128	GERWKALRRFSLATMRDFGMG	PKA_group	2583091	LTP	0.97	MOD_PKA_1	-	p450	0.10	-	medium

Substrate:

Cytochrome P450 2B2 (cytochrome P450 IIB2 (P450E) (from PhosphoBase))

Seq-ID:

P04167 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
heme binding, electron carrier activity, aromatase activity, steroid hydroxylase activity	microsome, endoplasmic reticulum membrane	oxidation reduction, drug metabolic process, response to organic cyclic substance, aging, response to calcium ion, nicotine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	128	GERWKALRRFSLATMRDFGMG	PKA_group	2583091	LTP	0.97	MOD_PKA_1	-	p450	0.10	-	low

Substrate:

DARPP-32 (Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32))

Seq-ID:

P07516 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity	cytoplasm	signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	34	QVEMIRRRRPTPAMLFRLSEH	PKA_group	3511054	LTP	1.00		-	DARPP-32	0.73	-	high

Substrate:

Dematin (Structural protein)

Seq-ID:

Q08495 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-64072 SMD2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
actin binding	cytoplasm, actin cytoskeleton	actin filament capping, actin filament bundle assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	403	WKRNELKKKASLF	PKA_group	7615546	LTP	0.00		-	VHP	0.24	-	-

Substrate:

Desmin (desmin (from PhosphoBase))

Seq-ID:

P02542 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity	intermediate filament, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	29	GGTSPVFPRASFGSRGSGSSV	PKA_group	3359992	LTP	0.69	MOD_PKA_2	-	Filament_head	0.50	-	low
S	35	FPRASFGSRGSGSSVTSRVYQ	PKA_group	3359992	LTP	0.83	MOD_PKA_2	-	Filament_head	0.41	-	low
S	50	TSRVYQVSRTSAVPTLSTFRT	PKA_group	3359992	LTP	0.97	MOD_PKA_2	-	Filament_head	0.39	-	low

Substrate:

Desmoplakin (Cytoskeletal protein)

Seq-ID:

P15924 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48119   IKKE_HUMAN
MINT-48557   NFKB1_HUMAN
MINT-49027   RELB_HUMAN
MINT-1792815   PKP4_HUMAN
MINT-3318871   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, protein binding, bridging	desmosome, cornified envelope	keratinocyte differentiation, peptide cross-linking

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2849	SGSRSGSRRGSFDATGNSSYS	PKA_group	7525582	LTP	1.00	MOD_PKA_1	-	-	0.58	-	-

Substrate:

DPDE4 (Enzyme: Phosphodiesterase)

Seq-ID:

Q07343 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, 3`,5`-cyclic-AMP phosphodiesterase activity	cytosol, insoluble fraction, soluble fraction	signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	133	TFPGHSQRRESFLYRSDSDYD	PKA_group	12441002	LTP	1.00	MOD_PKA_1	-	-	0.52	-	low

Substrate:

Drp1 (GTPase)

Seq-ID:

O00429 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, protein binding	cis-Golgi network, cytosol, mitochondrial outer membrane, endoplasmic reticulum, endomembrane system	mitochondrial fragmentation involved in apoptosis, mitochondrial membrane organization, cell communication, multicellular organismal development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	637	DVPVPVARKLSAREQRDCEVI	PKA_group	17553808	LTP	0.71	MOD_PKA_1	-	-	0.40	-	medium

Substrate:

Drp1 (GTPase)

Seq-ID:

O35303 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, protein binding	microsome, mitochondrion, cytosol, peroxisome, membrane, endomembrane system

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	656	DVPVPVARKLSAREQRDCEVI	PKA_group	17721437	LTP	0.69	MOD_PKA_1	-	-	0.40	-	low

Substrate:

E3 ubiquitin-protein ligase Nedd-4-like protein (Ubiquitin-protein ligase activity)

Seq-ID:

Q96PU5 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-61615 SMAD2_HUMAN
MINT-63860 GDIR1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sodium channel regulator activity, protein binding, ubiquitin-protein ligase activity	cytoplasm	positive regulation of endocytosis, water homeostasis, excretion, sodium ion transport, interspecies interaction between organisms, cellular sodium ion homeostasis, regulation of protein catabolic process, response to metal ion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	342	REPSSRLRSCSVTDAVAEQGH	PKA_group	15328345	LTP	0.96		-	-	0.73	-	medium
T	367	SAPAGRARSSTVTGGEEPTPS	PKA_group	15328345	LTP	0.04	MOD_PKA_2	-	-	0.90	-	medium
S	448	EPQIRRPRSLSSPTVTLSAPL	PKA_group	15328345	LTP	1.00		-	-	0.74	-	medium

Substrate:

eIF-2-beta (eukaryotic translation initation factor 2 beta subunit (from PhosphoBase))

Seq-ID:

P41035 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
translation initiation factor activity, metal ion binding

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	218	QVVRVGTKKTSFVNFTDICKL	PKA_group	8024572	LTP	0.21	MOD_PKA_1	-	eIF2B_5	0.18	-	medium

Substrate:

Erythrocyte band 7 integral membrane protein (erythrocyte band 7 integral membrane protein (stomatin) (from PhosphoBase))

Seq-ID:

P27105 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	integral to plasma membrane, melanosome, cytoskeleton, membrane raft	protein homooligomerization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	10	MAEKRHTRDSEAQRLPDSFK	PKA_group	8373790	LTP	0.14	MOD_PKA_1	-	-	0.49	-	low

Substrate:

Erythrocyte membrane protein band 4.2 (erythrocyte membrane protein band 4.2 (P4.2) (pallidin) (from PhosphoBase))

Seq-ID:

P16452 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, ATP binding, protein-glutamine gamma-glutamyltransferase activity, protein binding	plasma membrane, cytoplasm, cytoskeleton	erythrocyte maturation, regulation of cell shape, peptide cross-linking

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	248	EGALLNKRRGSVPILRQWLTG	PKA_group	8499466	LTP	1.00	MOD_PKA_1	-	Transglut_core	0.21	-	medium

Substrate:

Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )

Seq-ID:

P03372 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13786   BRCA1_HUMAN
MINT-50646   STA5A_HUMAN
MINT-50709   M3K1_HUMAN
MINT-5222241   NCOA1_HUMAN
MINT-6169667   EGFR_HUMAN
MINT-6614126   SMCA4_HUMAN
MINT-6614301   CHD3_HUMAN
MINT-6614361   MTA1_HUMAN
MINT-6614421   MTA2_HUMAN
MINT-6761899   PTN1_HUMAN
MINT-6761906   PTN6_HUMAN
MINT-7013584   PA1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
beta-catenin binding, nitric-oxide synthase regulator activity, estrogen response element binding, steroid binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, estrogen receptor activity	chromatin remodeling complex	response to estradiol stimulus, transcription, DNA-dependent, regulation of transcription, DNA-dependent, positive regulation of retinoic acid receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	236	QCTIDKNRRKSCQACRLRKCY	PKA_group	9891036	LTP	1.00	MOD_PKA_1	-	ZnF_C4	0.22	1HCQ	73.77%

Substrate:

ETV5 (transcription factor activity)

Seq-ID:

P41161 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
promoter binding, sequence-specific DNA binding transcription factor activity	nucleus	cellular response to oxidative stress, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	367	REGPPYQRRGSLQLWQFLVTL	PKA_group	11682477	LTP	1.00	MOD_PKA_1	-	ETS	0.21	-	low

Substrate:

FGF2 (protein binding)

Seq-ID:

P09038 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
fibroblast growth factor receptor binding, heparin binding, growth factor activity	extracellular space	branching involved in ureteric bud morphogenesis, positive regulation of cell fate specification, positive regulation of ERK1 and ERK2 cascade, positive regulation of blood vessel endothelial cell migration, positive regulation of cardiac muscle cell proliferation, negative regulation of cell death, negative regulation of blood vessel endothelial cell migration, activation of MAPK activity, chondroblast differentiation, chemotaxis, cell migration involved in sprouting angiogenesis, Ras protein signal transduction, positive regulation of cell division, fibroblast growth factor receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	121	NYNTYRSRKYTSWYVALKRTG	PKA_group	2541433	LTP	-	MOD_PKA_1	-	FGF	0.20	1BFG	53.42%

Substrate:

Fibrinogen alpha chain (fibrinogen (from PhosphoBase))

Seq-ID:

P02671 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-62797 BAT2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
eukaryotic cell surface binding, protein binding, bridging, receptor binding	external side of plasma membrane, fibrinogen complex, platelet alpha granule lumen	signal transduction, protein polymerization, response to calcium ion, platelet activation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	460	TSGSTTTTRRSCSKTVTKTVI	PKA_group	6255944	LTP	1.00	MOD_PKA_2	-	-	0.65	-	medium

Substrate:

Fructose-1,6-bisphosphatase (fructose-1,6-bisphosphatase (from PhosphoBase))

Seq-ID:

P09201 [Saccharomyces cerevisiae]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
fructose 1,6-bisphosphate 1-phosphatase activity, identical protein binding, metal ion binding	cytosol	gluconeogenesis, oxygen and reactive oxygen species metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	12	PTLVNGPRRDSTEGFDTDIIT	PKA_group	3005313	LTP	0.17	MOD_PKA_1	-	-	0.40	-	medium

Substrate:

Fructose-1,6-bisphosphatase (fructose-1,6-bisphosphatase (from PhosphoBase))

Seq-ID:

P19112 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
fructose 1,6-bisphosphate 1-phosphatase activity, metal ion binding, monosaccharide binding	cytosol, soluble fraction	gluconeogenesis, fructose 6-phosphate metabolic process, cellular response to insulin stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	339	LEIYNKDKAKSRPSLPLPQSR	PKA_group	2824503	LTP	0.14	MOD_PKA_2	-	-	0.48	-	medium
S	342	YNKDKAKSRPSLPLPQSRARE	PKA_group	6274412	LTP	0.48	MOD_PKA_2	-	-	0.61	-	medium
S	357	QSRARESPVHSICDELF	PKA_group	2824503	LTP	-		-	-	0.36	-	medium

Substrate:

G alpha 13 (G protein)

Seq-ID:

Q14344 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTPase activity, GTP binding, signal transducer activity	melanosome	cellular component movement

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	203	QQDILLARRPTKGIHEYDFEI	PKA_group	12399457	LTP	1.00	MOD_PKA_1	-	G_alpha	0.20	-	low

Substrate:

GABA(A) receptor B1 (gamma-aminobutyric-acid receptor beta-1 subunit precursor (from PhosphoBase))

Seq-ID:

P18505 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity	cell junction, integral to plasma membrane, chloride channel complex, postsynaptic membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	434	PSKGRIRRRASQLKVKIPDLT	PKA_group	1321150	LTP	0.79	MOD_PKA_1	-	Neur_chan_memb	0.42	-	medium

Substrate:

GFAP (glial fibrillary acidic protein, astrocyte (GFAP) (from PhosphoBase))

Seq-ID:

Q28115 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	intermediate filament, cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	7	MERRRVTSATRRSYVSS	PKA_group	2155236	LTP	0.11	MOD_PKA_1	-	Filament_head	0.53	-	medium
S	8	MERRRVTSATRRSYVSSS	PKA_group	2155236	LTP	0.95	MOD_PKA_1	-	Filament_head	0.53	-	medium
S	13	RRRVTSATRRSYVSSSEMVVG	PKA_group	2155236	LTP	0.72	MOD_PKA_2	-	Filament_head	0.47	-	medium
S	34	GRRLGPGTRLSLARMPPPLPA	PKA_group	2155236	LTP	1.00	MOD_PKA_2	-	Filament_head	0.58	-	medium

Substrate:

GFPT2 (glutamine-fructose-6-phosphate transaminase...)

Seq-ID:

O94808 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sugar binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity	cytoplasm	carbohydrate biosynthetic process, fructose 6-phosphate metabolic process, energy reserve metabolic process, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	202	PGEAVATRRGSPLLIGVRSKY	PKA_group	15133036	LTP	0.99		-	GATase_2	0.24	-	medium

Substrate:

Glucosamine--fructose-6-phosphate aminotransferase (Enzyme: Aminotransferase)

Seq-ID:

Q06210 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sugar binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity	cytoplasm	carbohydrate biosynthetic process, fructose 6-phosphate metabolic process, energy reserve metabolic process, glutamine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	205	PGQAVGTRRGSPLLIGVRSEH	PKA_group	10806197	LTP	0.99	-	GATase_2	0.38	-	medium
S	205	PGQAVGTRRGSPLLIGVRSEH	PKA_group	9836513	LTP	0.99	-	GATase_2	0.38	-	medium
S	235	LYRTARTQIGSKFTRWGSQGE	PKA_group	10806197	LTP	-	-	-	0.38	-	medium
S	235	LYRTARTQIGSKFTRWGSQGE	PKA_group	9836513	LTP	-	-	-	0.38	-	medium

Substrate:

GluR-1 (Extracellular ligand gated channel)

Seq-ID:

P42261 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-18147 KAPCA_HUMAN
MINT-49811 CXCR2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
kainate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity	endocytic vesicle membrane, cell junction, endoplasmic reticulum membrane, postsynaptic membrane	synaptic transmission

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	863	AIRTSTLPRNSGAGASSGGSG	PKA_group	8663994	LTP	0.42	MOD_PKA_2	-	-	0.60	-	low

Substrate:

GluR-4 (Extracellular ligand gated channel)

Seq-ID:

P48058 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-17826 KCC2A_HUMAN
MINT-49874 KAPCA_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
extracellular-glutamate-gated ion channel activity	endocytic vesicle membrane, cell junction, postsynaptic membrane	glutamate signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	862	SEAIRNKARLSITGSVGENGR	PKA_group	10366608	LTP	0.94	MOD_PKA_2	-	-	0.30	-	low

Substrate:

GluR-6 (glutamate receptor 6 precursor (GluR-6) (glutamate receptor, (from PhosphoBase))

Seq-ID:

Q13002 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
kainate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity	cell junction, postsynaptic membrane	positive regulation of synaptic transmission, neuron apoptosis, regulation of short-term neuronal synaptic plasticity, glutamate signaling pathway, induction of programmed cell death in response to chemical stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	697	DGATMTFFKKSKISTYDKMWA	PKA_group	8382377	LTP	0.98		-	PBPe	0.09	1S50	16.39%
S	715	MWAFMSSRRQSVLVKSNEEGI	PKA_group	8382377	LTP	0.82	MOD_PKA_1	-	PBPe	0.22	1S50	45.08%

Substrate:

Glycogenin-1 (glycogenin (from PhosphoBase))

Seq-ID:

P13280 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
glycogenin glucosyltransferase activity		glycogen biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	44	RLAVLTTPQVSDTMRKALEIV	PKA_group	3151442	LTP	0.97		-	Glyco_transf_8	0.22	1LL2	34.43%

Substrate:

GMF-beta (Glia maturation factor)

Seq-ID:

P60983 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
enzyme activator activity, protein kinase inhibitor activity, growth factor activity, actin binding, signal transducer activity	intracellular	nervous system development, protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	27	KLRKFRFRKETNNAAIIMKID	PKA_group	9030586	LTP	0.31	MOD_PKA_1	-	ADF	0.19	-	medium
S	83	YKYQHDDGRVSYPLCFIFSSP	PKA_group	9030586	LTP	0.96	MOD_PKA_2	-	ADF	0.09	-	medium

Substrate:

GRK7 (ser/thr kinase)

Seq-ID:

Q8WTQ7 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
G-protein coupled receptor kinase activity, ATP binding, signal transducer activity	membrane	protein amino acid phosphorylation, visual perception, response to stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	23	NTAYLQARKPSDCDSKELQRR	PKA_group	15946941	LTP	0.04	MOD_PKA_1	-	-	0.43	-	medium
S	36	DSKELQRRRRSLALPGLQGCA	PKA_group	15946941	LTP	0.19	MOD_PKA_1	-	-	0.38	-	medium

Substrate:

GSK-3 alpha (Glycogen synthase kinase-3 alpha)

Seq-ID:

P49840 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-4544606 AXN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, tau-protein kinase activity, ATP binding, protein kinase A catalytic subunit binding	beta-catenin destruction complex, cytosol	positive regulation of protein catabolic process, protein amino acid phosphorylation, negative regulation of insulin receptor signaling pathway, negative regulation of transferase activity, negative regulation of glucose import, insulin receptor signaling pathway, negative regulation of UDP-glucose catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	PGGSGRARTSSFAEPGGGGGG	PKA_group	11035810	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium

Substrate:

GSK-3 beta (Glycogen synthase kinase-3 beta)

Seq-ID:

P49841 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-65985   DBPA_HUMAN
MINT-65986   YBOX1_HUMAN
MINT-2837737   PSN1_HUMAN
MINT-3974216   TAU_HUMAN
MINT-4049759   PCM1_HUMAN
MINT-4049773   NIN_HUMAN
MINT-4508051   CTNB1_HUMAN
MINT-4508259   AXN1_HUMAN
MINT-4793253   P53_HUMAN
MINT-6761890   PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, tau-protein kinase activity, p53 binding, beta-catenin binding, ATP binding, protein kinase A catalytic subunit binding, NF-kappaB binding	Axin-APC-beta-catenin-GSK3B complex, beta-catenin destruction complex, cytosol, nucleus	positive regulation of protein catabolic process, hippocampus development, negative regulation of apoptosis, positive regulation of protein export from nucleus, positive regulation of Rac GTPase activity, positive regulation of protein complex assembly, peptidyl-serine phosphorylation, glycogen metabolic process, superior temporal gyrus development, canonical Wnt receptor signaling pathway, ER overload response, negative regulation of protein binding, positive regulation of cell-matrix adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	9	MSGRPRTTSFAESCKPVQQ	PKA_group	11035810	LTP	0.60	MOD_PKA_2	-	-	0.61	-	-

Substrate:

HAND1 (Transcription factor)

Seq-ID:

O96004 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, protein homodimerization activity, bHLH transcription factor binding, transcription coactivator activity	cytoplasm, nucleolus, nucleoplasm	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, cardiac left ventricle formation, positive regulation of gene-specific transcription from RNA polymerase II promoter, angiogenesis, cardiac septum morphogenesis, cardiac right ventricle formation, heart looping, ventricular cardiac muscle tissue morphogenesis, trophectodermal cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	98	LGGRLGRRKGSGPKKERRRTE	PKA_group	14636580	LTP	0.22	MOD_PKA_1	-	HLH	0.85	-	medium
T	107	GSGPKKERRRTESINSAFAEL	PKA_group	14636580	LTP	1.00	MOD_PKA_1	-	HLH	0.70	-	medium
S	109	GPKKERRRTESINSAFAELRE	PKA_group	14636580	LTP	1.00	MOD_PKA_1	-	HLH	0.63	-	medium

Substrate:

HDAC8 (histone deacetylase activity, transcription factor binding)

Seq-ID:

Q9BY41 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-5207405 P53_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
metal ion binding, histone deacetylase activity, transcription factor binding	histone deacetylase complex, cytoplasm, nuclear chromosome	transcription, histone deacetylation, chromatin assembly or disassembly, negative regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	39	DSLAKIPKRASMVHSLIEAYA	PKA_group	14701748	LTP	0.20	MOD_PKA_1	-	Hist_deacetyl	0.15	3EW8	22.95%

Substrate:

Histone H1.1

Seq-ID:

P02253 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	nucleosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	35	KKPAGARRKASGPPVSELITK	PKA_group	1137958	LTP	1.00	MOD_PKA_1	-	H15	0.64	-	medium

Substrate:

Histone H2A.c/d/i/n/p (histone H2A.1 (from PhosphoBase))

Seq-ID:

P0C0S9 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	nucleus, nucleosome	nucleosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	20	KARAKAKTRSSRAGLQFPVGR	PKA_group	1137958	LTP	-	MOD_PKA_2	-	H2A	0.50	2CV5	59.02%

Substrate:

Histone H2B.a/g/h/k/l (histone H2B (from PhosphoBase))

Seq-ID:

P62807 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding, protein binding	nucleus, nucleosome	defense response to bacterium, nucleosome assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	15	AKSAPAPKKGSKKAVTKAQKK	PKA_group	1137958	LTP	0.00	MOD_PKA_1	-	-	0.79	-	-
S	33	QKKDGKKRKRSRKESYSVYVY	PKA_group	192223	LTP	0.30	MOD_PKA_1	-	H2B	0.53	2CV5	98.36%
S	37	GKKRKRSRKESYSVYVYKVLK	PKA_group	192223	LTP	1.00	MOD_PKA_1	-	H2B	0.42	2CV5	47.54%

Substrate:

HLA-A1 (MHC complex protein)

Seq-ID:

P30443 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
MHC class I receptor activity	MHC class I protein complex, integral to plasma membrane	immune response, interspecies interaction between organisms, antigen processing and presentation of peptide antigen via MHC class I

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	336	VVAAVMWRRKSSDRKGGSYTQ	PKA_group	6333425	LTP	0.95	MOD_PKA_1	-	MHC_I_C	0.38	-	medium
S	337	VAAVMWRRKSSDRKGGSYTQA	PKA_group	6333425	LTP	0.95	MOD_PKA_1	-	MHC_I_C	0.41	-	medium
S	343	RRKSSDRKGGSYTQAASSDSA	PKA_group	6333425	LTP	0.89		-	MHC_I_C	0.61	-	medium

Substrate:

HMG14 (Transcription regulatory protein)

Seq-ID:

P02316 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	chromatin, nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	MPKRKVSSAEGAAKEEPK	PKA_group	6279643	LTP	0.00	MOD_PKA_1	-	HMG17	0.91	-	medium

Substrate:

HMG14 (Transcription regulatory protein)

Seq-ID:

P05114 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
positive transcription elongation factor activity, DNA binding, RNA polymerase II transcription factor activity	cytoplasm, chromatin, nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	GAAKEEPKRRSARLSAKPPAK	PKA_group	11438671	LTP	1.00	MOD_PKA_1	-	HMG17	0.91	-	medium
S	25	EEPKRRSARLSAKPPAKVEAK	PKA_group	11438671	LTP	1.00	MOD_PKA_2	-	HMG17	0.91	-	medium

Substrate:

hnRPA1 (RNA binding protein)

Seq-ID:

P09651 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-48852   M3K14_HUMAN
MINT-62794   BAT2_HUMAN
MINT-3296922   1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nucleotide binding, single-stranded RNA binding, single-stranded DNA binding, protein binding	spliceosomal complex, cytoplasm, nucleolus, nucleoplasm, heterogeneous nuclear ribonucleoprotein complex	mRNA transport, nuclear import, interspecies interaction between organisms, RNA export from nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	199	ASSSQRGRSGSGNFGGGRGGG	PKA_group	8451194	LTP	0.27		-	-	0.70	-	-

Substrate:

hnRPD (Ribonucleoprotein)

Seq-ID:

Q14103 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
nucleotide binding, transcription activator activity, telomeric DNA binding, RNA binding, protein binding	chromosome, heterogeneous nuclear ribonucleoprotein complex	transcription, regulation of transcription, DNA-dependent, RNA catabolic process, RNA splicing

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	87	EGHSNSSPRHSEAATAQREEW	PKA_group	12819195	LTP	-	MOD_PKA_2	-	-	0.85	-	-

Substrate:

HRH1 (G-protein coupled receptor activity, histamine receptor activity)

Seq-ID:

P35367 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
histamine receptor activity	integral to plasma membrane	inflammatory response, activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	398	KFTWKRLRSHSRQYVSGLHMN	PKA_group	15107581	LTP	1.00		-	7tm_1	0.19	-	medium

Substrate:

HSP27 (heat shock 27 kD protein (HSP 27) (from PhosphoBase))

Seq-ID:

P14602 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	plasma membrane, insoluble fraction, soluble fraction, nucleus, Z disc	response to heat

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	15	RVPFSLLRSPSWEPFRDWYPA	PKA_group	1332886	LTP	1.00		-	-	0.14	-	medium
S	86	AFSRALNRQLSSGVSEIRQTA	PKA_group	1332886	LTP	0.31		-	-	0.41	-	medium

Substrate:

Inositol 1,4,5-trisphosphate receptor type 1 (inositol 1,4,5-trisphosphate-binding protein type 1 receptor (from PhosphoBase))

Seq-ID:

P29994 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, protein binding	plasma membrane, secretory granule membrane, integral to membrane, endoplasmic reticulum membrane, membrane raft, postsynaptic density	elevation of cytosolic calcium ion concentration

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1756	GNIRPSGRRESLTSFGNGPLS	PKA_group	7935353	LTP	0.50	MOD_PKA_1	-	-	0.64	-	medium

Substrate:

Integrin alpha 4 (Cell surface receptor)

Seq-ID:

P13612 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
receptor activity, identical protein binding	integrin complex	B cell differentiation, integrin-mediated signaling pathway, leukocyte cell-cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1027	SILQEENRRDSWSYINSKSND	PKA_group	11533025	LTP	0.05	MOD_PKA_1	-	-	0.36	-	medium

Substrate:

IPP1 (protein phosphatase inhibitor 1 (IPP-1) (from PhosphoBase))

Seq-ID:

P01099 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity		signal transduction, glycogen metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	35	AAEQIRRRRPTPATLVLTSDQ	PKA_group	193727	LTP	1.00		-	DARPP-32	0.89	-	medium

Substrate:

L-plastin (Calcium binding protein)

Seq-ID:

P13796 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding	cell junction, cytosol, ruffle membrane	T cell activation involved in immune response, regulation of intracellular protein transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	5	MARGSVSDEEMMELR	PKA_group	10446213	LTP	0.28	MOD_PKA_2	-	-	0.45	-	medium
S	7	MARGSVSDEEMMELREA	PKA_group	10446213	LTP	0.81	MOD_PKA_2	-	-	0.41	-	medium

Substrate:

Lamin Dm0 (lamin Dm0 (from PhosphoBase))

Seq-ID:

P08928 [Drosophila melanogaster]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-42096 IMA_DROME
MINT-42822 OTE_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, receptor binding	lipid particle, microtubule associated complex, lamin filament, nuclear envelope	gonad morphogenesis, terminal branching, open tracheal system, central nervous system development, compound eye morphogenesis, nuclear migration, chromatin silencing, chitin-based cuticle development, mitotic nuclear envelope reassembly, digestive tract morphogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	50	ASSPLSPTRHSRVAEKVELQN	PKA_group	9013881	LTP	1.00	MOD_PKA_2	-	-	0.80	-	medium

Substrate:

LASP1 (Cytoskeletal protein)

Seq-ID:

Q14847 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-66300 TRP13_HUMAN
MINT-66313 PLS1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ion transmembrane transporter activity, SH3/SH2 adaptor activity, zinc ion binding, actin binding	focal adhesion, cortical actin cytoskeleton

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	146	GEGMEPERRDSQDGSSYRRPL	PKA_group	12571245	LTP	0.95	MOD_PKA_1	-	-	0.90	-	low

Substrate:

Lipase hormone sensitive (Enzyme: Lipase)

Seq-ID:

P15304 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-7211789 KAPCA_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
rRNA primary transcript binding, acylglycerol lipase activity, RNA polymerase I transcription termination factor activity, hormone-sensitive lipase activity, protein binding	lipid particle, mitochondrion, caveola, cytosol, extracellular space, nucleus	triglyceride catabolic process, response to drug, female pregnancy, cholesterol metabolic process, transcription initiation from RNA polymerase I promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	863	SGRLTESMRRSVSEAALAQPE	PKA_group	15294048	LTP	0.17	MOD_PKA_2	-	Abhydrolase_3	0.63	-	medium
S	959	AFPDGFHPRRSSQGVLHMPLY	PKA_group	15294048	LTP	0.13	MOD_PKA_1	-	Abhydrolase_3	0.44	-	medium
S	960	FPDGFHPRRSSQGVLHMPLYS	PKA_group	15294048	LTP	0.32	MOD_PKA_1	-	Abhydrolase_3	0.42	-	medium

Substrate:

Lipase hormone sensitive (Enzyme: Lipase)

Seq-ID:

P16386 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
rRNA primary transcript binding, RNA polymerase I transcription termination factor activity, hormone-sensitive lipase activity, lipase activity	mitochondrion, caveola, cytosol, nucleus	lipid catabolic process, cholesterol metabolic process, transcription initiation from RNA polymerase I promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	8	KTEPMRRSVSEAALTQPE	PKA_group	3345839	LTP	0.79	MOD_PKA_2	-	-	0.92	-	medium

Substrate:

Lipase hormone sensitive (Enzyme: Lipase)

Seq-ID:

Q05469 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
hormone-sensitive lipase activity, protein binding	caveola, cytosol	protein amino acid phosphorylation, cholesterol metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	853	SEPIAEPMRRSVSEAALAQPQ	PKA_group	3345839	LTP	0.17	MOD_PKA_2	-	Abhydrolase_3	0.69	-	medium
S	853	SEPIAEPMRRSVSEAALAQPQ	PKA_group	16188906	LTP	0.17	MOD_PKA_2	-	Abhydrolase_3	0.69	-	medium
S	855	PIAEPMRRSVSEAALAQPQGP	PKA_group	15033481	LTP	0.43	MOD_PKA_2	-	Abhydrolase_3	0.72	-	medium
S	950	AFPEGFHPRRSSQGATQMPLY	PKA_group	9417067	LTP	0.13	MOD_PKA_1	-	Abhydrolase_3	0.62	-	medium
S	951	FPEGFHPRRSSQGATQMPLYS	PKA_group	9417067	LTP	0.32	MOD_PKA_1	-	Abhydrolase_3	0.60	-	medium

Substrate:

Lipocortin I (annexinI) ( Ca++, phospholipids and actin-binding protein)

Seq-ID:

P04083 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-51101 EGFR_HUMAN
MINT-3297886 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium-dependent phospholipid binding, calcium ion binding, phospholipase A2 inhibitor activity, protein binding, bridging, structural molecule activity, receptor binding	extracellular region, cilium, cytoplasm, basolateral plasma membrane, cornified envelope, nucleus	positive regulation of vesicle fusion, lipid metabolic process, keratinocyte differentiation, anti-apoptosis, cellular component movement, signal transduction, inflammatory response, cell surface receptor linked signaling pathway, peptide cross-linking

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	216	LYEAGERRKGTDVNVFNTILT	PKA_group	2457390	LTP	1.00	MOD_PKA_1	-	ANX	0.31	1AIN	0.0%

Substrate:

Lysozyme C (egg white lysozyme C (from PhosphoBase))

Seq-ID:

P00698 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
lysozyme activity	extracellular space	defense response to bacterium, cell wall macromolecule catabolic process, cytolysis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	42	RHGLDNYRGYSLGNWVCAAKF	PKA_group	169238	LTP	1.00		-	LYZ1	0.05	1V7S	39.34%
S	68	TQATNRNTDGSTDYGILQINS	PKA_group	169238	LTP	1.00	MOD_PKA_2	-	LYZ1	0.28	1V7S	0.00%

Substrate:

MBP (myelin basic protein (MBP) (from PhosphoBase))

Seq-ID:

P02687 [Bos taurus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6613181 MK01_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of myelin sheath, protein binding	plasma membrane, myelin sheath

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	7	AAQKRPSQRSKYLASAS	PKA_group	2413024	LTP	0.42	MOD_PKA_1	-	-	0.80	-	low
S	10	AAQKRPSQRSKYLASASTMD	PKA_group	2413024	LTP	0.12	MOD_PKA_1	-	-	0.82	-	low
T	33	RHGFLPRHRDTGILDSLGRFF	PKA_group	4833512	LTP	0.17	MOD_PKA_2	-	Myelin_MBP	0.52	-	low
S	54	GSDRGAPKRGSGKDGHHAART	PKA_group	2413024	LTP	0.45	MOD_PKA_1	-	Myelin_MBP	0.87	-	low
S	109	PPSQGKGRGLSLSRFSWGAEG	PKA_group	4833512	LTP	1.00		-	Myelin_MBP	0.71	-	low
S	131	KPGFGYGGRASDYKSAHKGLK	PKA_group	2413024	LTP	0.87	MOD_PKA_2	-	Myelin_MBP	0.63	-	low
S	160	SKIFKLGGRDSRSGSPMARR	PKA_group	2413024	LTP	1.00	MOD_PKA_2	-	Myelin_MBP	0.71	-	low

Substrate:

Melanocortin 4 receptor (G protein coupled receptor)

Seq-ID:

P32245 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ubiquitin protein ligase binding, neuropeptide binding, melanocyte-stimulating hormone receptor activity	plasma membrane, integral to membrane	positive regulation of cAMP biosynthetic process, positive regulation of bone resorption, feeding behavior, G-protein signaling, coupled to cAMP nucleotide second messenger

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	312	YALRSQELRKTFKEIICCYPL	PKA_group	12639913	LTP	1.00	MOD_PKA_2	-	7TM_GPCR_Srsx	0.01	-	low
S	329	CYPLGGLCDLSSRY	PKA_group	12639913	LTP	0.20		-	-	0.01	-	low
S	330	YPLGGLCDLSSRY	PKA_group	12639913	LTP	0.00		-	-	0.01	-	low

Substrate:

Merlin (Probably acts as a ,15, stabilizing protein)

Seq-ID:

P35240 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cytoskeletal protein binding	early endosome, cytoskeleton, nucleolus, ruffle membrane, extrinsic to membrane, perinuclear region of cytoplasm, filopodium membrane	negative regulation of DNA replication, actin cytoskeleton organization, negative regulation of tyrosine phosphorylation of Stat5 protein, positive regulation of stress fiber assembly, negative regulation of cell proliferation, regulation of hippo signaling cascade, negative regulation of cell-matrix adhesion, Schwann cell proliferation, negative regulation of cell-cell adhesion, negative regulation of cell migration, negative regulation of tyrosine phosphorylation of Stat3 protein

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	518	DFKDTDMKRLSMEIEKEKVEY	PKA_group	14981079	LTP	1.00	MOD_PKA_1	-	COIL	0.46	-	medium

Substrate:

MHC class II transactivator (Transcription regulatory protein)

Seq-ID:

P33076 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, protein C-terminus binding, RNA polymerase II transcription factor activity, transcription activator binding, ATP binding, transcription coactivator activity, ubiquitin binding, promoter binding, protein complex binding	nucleus	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription, response to interferon-gamma, positive regulation of MHC class II biosynthetic process, response to antibiotic, positive regulation of transcription from RNA polymerase II promoter, negative regulation of collagen biosynthetic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	834	HVVQELPGRLSFLGTRLTPPD	PKA_group	11416140	LTP	1.00	MOD_PKA_2	-	-	0.30	-	medium
S	1050	PSLAASLLRLSLYNNCICDVG	PKA_group	11416140	LTP	0.18	MOD_PKA_2	-	LRR	0.04	-	medium

Substrate:

MLCK (Serine/threonine Kinase)

Seq-ID:

Q15746 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7250086 NCK1_HUMAN
MINT-7252174 P85A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
myosin light chain kinase activity, metal ion binding, ATP binding, actin binding, calmodulin binding	cytosol	protein amino acid phosphorylation, muscle contraction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	13	DVKLVASSHISKTSLSVDPSR	PKA_group	11964068	LTP	1.00		-	-	0.39	-	medium

Substrate:

Moesin (Adapter molecule)

Seq-ID:

P26038 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, cell adhesion molecule binding, receptor binding	filopodium, cytoplasm, cytoskeleton, nucleolus, microvillus membrane, extrinsic to membrane, apical plasma membrane	membrane to membrane docking, leukocyte cell-cell adhesion, leukocyte migration

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	558	NMRLGRDKYKTLRQIRQGNTK	PKA_group	15634677	LTP	0.98		-	ERM	0.69	-	medium

Substrate:

Mybpc3 (Myosin-binding protein)

Seq-ID:

O70468 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of cytoskeleton, myosin heavy chain binding, actin binding	A band	myosin filament assembly, heart morphogenesis, cardiac muscle contraction, regulation of heart rate, cell adhesion, sarcomere organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	273	LDLRSAFRRTSLAGAGRRTSD	PKA_group	20151718	LTP	1.00	MOD_PKA_1	-	-	0.46	-	low
S	282	TSLAGAGRRTSDSHEDAGTPD	PKA_group	20151718	LTP	0.15	MOD_PKA_1	-	-	0.67	-	low
S	302	DFSSLLKKRDSFRRDSKLEAP	PKA_group	20151718	LTP	0.20	MOD_PKA_1	-	-	0.44	-	low
S	307	LKKRDSFRRDSKLEAPAEEDV	PKA_group	20151718	LTP	0.30	MOD_PKA_1	-	-	0.46	-	low

Substrate:

Mybpc3 (Myosin-binding protein)

Seq-ID:

Q14896 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATPase activator activity, myosin heavy chain binding, structural constituent of muscle, titin binding, actin binding	C zone, striated myosin muscle thick filament	positive regulation of ATPase activity, regulation of striated muscle contraction, regulation of muscle filament sliding, cardiac muscle contraction, ventricular cardiac muscle tissue morphogenesis, cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	275	LDLLSAFRRTSLAGGGRRISD	PKA_group	20151718	LTP	1.00	MOD_PKA_1	-	-	0.30	-	low
S	275	LDLLSAFRRTSLAGGGRRISD	PKA_group	18802026	LTP	1.00	MOD_PKA_1	-	-	0.30	-	low
S	284	TSLAGGGRRISDSHEDTGILD	PKA_group	20151718	LTP	0.14	MOD_PKA_1	-	-	0.42	-	low
S	284	TSLAGGGRRISDSHEDTGILD	PKA_group	18802026	LTP	0.14	MOD_PKA_1	-	-	0.42	-	low
S	304	DFSSLLKKSSSFRTPRDSKLE	PKA_group	20151718	LTP	0.20	MOD_PKA_1	-	-	0.36	-	low
S	304	DFSSLLKKSSSFRTPRDSKLE	PKA_group	18802026	LTP	0.20	MOD_PKA_1	-	-	0.36	-	low
S	311	KSSSFRTPRDSKLEAPAEEDV	PKA_group	20151718	LTP	0.01	MOD_PKA_2	-	-	0.49	-	low

Substrate:

MYOM1 (structural constituent of muscle)

Seq-ID:

P52179 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of muscle	striated myosin muscle thick filament

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	482	AEKARLKSPLSTLDWTVIVTE	PKA_group	9029142	LTP	0.00		-	-	0.29	-	medium

Substrate:

Neurabin II protein (Cytoskeletal protein)

Seq-ID:

Q96SB3 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-62199 PP1A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoprotein phosphatase inhibitor activity, protein phosphatase 1 binding, actin binding	dendritic spine, cell junction, protein phosphatase type 1 complex, cytoskeleton, synapse, nucleoplasm	nervous system development, negative regulation of cell growth, cell cycle arrest, regulation of exit from mitosis, regulation of cell proliferation, regulation of cell growth by extracellular stimulus, RNA splicing, cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	94	PRASERGVRLSLPRASSLNEN	PKA_group	12417592	LTP	0.21	MOD_PKA_2	-	-	0.75	-	medium
S	100	GVRLSLPRASSLNENVDHSAL	PKA_group	12417592	LTP	1.00	MOD_PKA_2	-	-	0.62	-	medium

Substrate:

Neutrophil cytosol factor 1 (Neutrophil cytosol factor 1)

Seq-ID:

P14598 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-58638   TF65_HUMAN
MINT-66383   TRIM9_HUMAN
MINT-74863   ACTB_HUMAN
MINT-3973484   KPCA_HUMAN
MINT-3973536   KPCD_HUMAN
MINT-7135171   GNAI2_HUMAN
MINT-7300360   NCF4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
SH3 domain binding, phosphoinositide binding, GTPase activity, GTP binding, electron carrier activity	cytosol, NADPH oxidase complex, soluble fraction	protein targeting to membrane, superoxide anion generation, cellular defense response, innate immune response, cell communication, respiratory burst

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	303	QIKRGAPPRRSSIRNAHSIHQ	PKA_group	7520867	LTP	1.00	MOD_PKA_1	-	-	0.76	1NG2	44.26%
S	320	SIHQRSRKRLSQDAYRRNSVR	PKA_group	8626435	LTP	1.00	MOD_PKA_1	-	-	0.59	1NG2	58.20%
S	320	SIHQRSRKRLSQDAYRRNSVR	PKA_group	7520867	LTP	1.00	MOD_PKA_1	-	-	0.59	1NG2	58.20%
S	328	RLSQDAYRRNSVRFLQQRRRQ	PKA_group	8626435	LTP	0.99	MOD_PKA_1	-	-	0.56	1NG2	0.00%
S	348	QARPGPQSPGSPLEEERQTQR	PKA_group	8626435	LTP	0.81	MOD_CK2_1	-	p47_phox_C	0.94	-	-
S	359	PLEEERQTQRSKPQPAVPPRP	PKA_group	8626435	LTP	0.71	MOD_PKA_2	-	p47_phox_C	0.94	-	-
S	370	KPQPAVPPRPSADLILNRCSE	PKA_group	8626435	LTP	1.00	MOD_PKA_2	-	p47_phox_C	0.80	-	-

Substrate:

NF-ATc1 (Transcription factor)

Seq-ID:

O95644 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-3319626 1433Z_HUMAN
MINT-6166975 OGT1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
FK506 binding, transcription activator activity, promoter binding, sequence-specific DNA binding transcription factor activity, protein binding	cytoplasm, nucleus	intracellular signaling pathway, transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	245	RHSPSTSPRASVTEESWLGAR	PKA_group	9072970	LTP	1.00	MOD_PKA_2	-	-	0.73	-	low
S	269	PASPCNKRKYSLNGRQPPYSP	PKA_group	9072970	LTP	0.94	MOD_PKA_1	-	-	0.68	-	low
S	294	TPSPHGSPRVSVTDDSWLGNT	PKA_group	12351631	LTP	1.00	MOD_PKA_2	-	-	0.77	-	low

Substrate:

NFE2L1 (transcription cofactor activity, transcription factor activity)

Seq-ID:

Q14494 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, protein dimerization activity, transcription cofactor activity, sequence-specific DNA binding transcription factor activity	nucleus	transcription from RNA polymerase II promoter, heme biosynthetic process, anatomical structure morphogenesis, inflammatory response, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	599	LPPPSALKKGSKEKQADFLDK	PKA_group	15308669	LTP	0.20	MOD_PKA_1	-	-	0.62	-	medium

Substrate:

NIPP1 (RNA binding protein)

Seq-ID:

Q12972 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-15257   CDC5L_HUMAN
MINT-62188   PP1A_HUMAN
MINT-64092   STC2_HUMAN
MINT-64094   SETB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding, protein serine/threonine phosphatase inhibitor activity, endonuclease activity, ribonuclease E activity, RNA binding, protein binding	spliceosomal complex, cytoplasm, nuclear speck	mRNA processing, transcription, regulation of transcription, RNA catabolic process, RNA splicing

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	178	EFNTAHNKRISTLTIEEGNLD	PKA_group	9407077	LTP	1.00	MOD_PKA_1	-	-	0.55	-	medium
S	199	IQRPKRKRKNSRVTFSEDDEI	PKA_group	9407077	LTP	0.19	MOD_PKA_1	-	-	0.70	-	medium

Substrate:

Nitric-oxide synthase, brain (Enzyme: Synthetase)

Seq-ID:

P29476 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-58323 AT2B4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amino acid binding, protein homodimerization activity, heme binding, cadmium ion binding, enzyme binding, NADP or NADPH binding, FAD binding, calmodulin binding, nitric-oxide synthase activity, FMN binding	dendritic spine, cytosol, nuclear membrane, synapse, photoreceptor inner segment, mitochondrial outer membrane, azurophil granule, perinuclear region of cytoplasm, sarcolemma	response to organic nitrogen, negative regulation of blood pressure, response to vitamin E, oxidation reduction, response to hypoxia, response to estrogen stimulus, response to organic cyclic substance, aging, response to heat, arginine catabolic process, negative regulation of insulin secretion, nitric oxide biosynthetic process, negative regulation of heart contraction, regulation of sensory perception of pain, response to ethanol, positive regulation of vasodilation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	374	QYYSSIKRFGSKAHMDRLEEV	PKA_group	1721813	LTP	1.00		-	NO_synthase	0.32	1OM4	25.41%

Substrate:

Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)

Seq-ID:

P29474 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
arginine binding, actin monomer binding, heme binding, cadmium ion binding, NADP or NADPH binding, FAD binding, calmodulin binding, nitric-oxide synthase activity, tetrahydrobiopterin binding, FMN binding	Golgi membrane, caveola, cytosol, cytoskeleton	regulation of blood vessel size, positive regulation of vasodilation, oxidation reduction, blood vessel remodeling, regulation of systemic arterial blood pressure by endothelin, anti-apoptosis, response to heat, positive regulation of guanylate cyclase activity, arginine catabolic process, negative regulation of muscle hyperplasia, positive regulation of angiogenesis, nitric oxide biosynthetic process, smooth muscle hyperplasia, endothelial cell migration, negative regulation of platelet activation, response to fluid shear stress, mitochondrion organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	633	VSSWRRKRKESSNTDSAGALG	PKA_group	12171920	LTP	0.04	MOD_PKA_1	-	Flavodoxin_1	0.47	-	-

Substrate:

Nopp140 (Transcription factor)

Seq-ID:

Q14978 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-73494 VE7_HPV16
MINT-3296095 1433Z_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTP binding, ATP binding, protein binding	cytoplasm, nucleolus	rRNA processing, mitosis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	623	KRKKGEKRASSPFRRVREEEI	PKA_group	12167624	LTP	0.65	MOD_PKA_1	-	SRP40_C	0.71	-	medium

Substrate:

NPR-A (Guanylate cyclase)

Seq-ID:

P16066 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-61913 MCAF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
GTP binding, guanylate cyclase activity, ATP binding, peptide receptor activity, G-protein coupled, protein kinase activity, natriuretic peptide receptor activity	integral to plasma membrane	regulation of blood vessel size, protein amino acid phosphorylation, diuresis, receptor guanylyl cyclase signaling pathway, negative regulation of angiogenesis, regulation of blood pressure, negative regulation of cell growth, natriuresis, regulation of vasodilation, regulation of vascular permeability

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	529	SLERHLRSAGSRLTLSGRGSN	PKA_group	9528788	LTP	1.00	MOD_PKA_2	-	STYKc	0.37	-	medium

Substrate:

Nuclear factor NF-kappa-B p105 subunit (Nuclear factor NF-kappa-B p105 subunit)

Seq-ID:

P19838 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-47827   M3K8_HUMAN
MINT-47861   IKBB_HUMAN
MINT-48545   TPR_HUMAN
MINT-48546   KCRB_HUMAN
MINT-48547   CLH1_HUMAN
MINT-48555   VIME_HUMAN
MINT-48556   ADT3_HUMAN
MINT-48557   DESP_HUMAN
MINT-48560   JIP4_HUMAN
MINT-48561   COPB2_HUMAN
MINT-48636   BAG2_HUMAN
MINT-48638   NEMO_HUMAN
MINT-48639   HS71L_HUMAN
MINT-48640   GRP78_HUMAN
MINT-48641   HSP7C_HUMAN
MINT-48642   HNRPF_HUMAN
MINT-48643   IKKA_HUMAN
MINT-48644   ADT2_HUMAN
MINT-48645   GRP75_HUMAN
MINT-48646   RUVB2_HUMAN
MINT-48648   IMA3_HUMAN
MINT-48650   DNJA1_HUMAN
MINT-48651   IMA4_HUMAN
MINT-48653   C1QBP_HUMAN
MINT-48654   EF1A2_HUMAN
MINT-48655   MATR3_HUMAN
MINT-48656   IKBA_HUMAN
MINT-48659   MYH10_HUMAN
MINT-48660   PYR1_HUMAN
MINT-48663   ACTG_HUMAN
MINT-48665   STUB1_HUMAN
MINT-48666   REL_HUMAN
MINT-48669   TBB6_HUMAN
MINT-48670   CALM_HUMAN
MINT-48671   NONO_HUMAN
MINT-48672   TBB5_HUMAN
MINT-48673   TBB4_HUMAN
MINT-48675   K1967_HUMAN
MINT-48677   DNJA3_HUMAN
MINT-48678   MYH9_HUMAN
MINT-48679   RS8_HUMAN
MINT-48680   SFPQ_HUMAN
MINT-48682   HS90A_HUMAN
MINT-48684   PRKDC_HUMAN
MINT-48685   MYL6_HUMAN
MINT-48687   HNRPM_HUMAN
MINT-48688   HS90B_HUMAN
MINT-48689   ML12A_HUMAN
MINT-48724   NFKB2_HUMAN
MINT-48996   RELB_HUMAN
MINT-50169   HDAC1_HUMAN
MINT-7023862   CTNB1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
promoter binding, sequence-specific DNA binding transcription factor activity, protein binding	cytosol, I-kappaB/NF-kappaB complex, nucleoplasm	negative regulation of gene-specific transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, positive regulation of transcription, negative regulation of cellular protein metabolic process, apoptosis, anti-apoptosis, negative regulation of cholesterol transport, membrane protein intracellular domain proteolysis, positive regulation of lipid storage, signal transduction, inflammatory response, positive regulation of macrophage derived foam cell differentiation, negative regulation of vitamin D biosynthetic process, negative regulation of calcidiol 1-monooxygenase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	337	ASVFVQLRRKSDLETSEPKPF	PKA_group	12947093	LTP	1.00	MOD_PKA_1	-	IPT	0.42	1U3J	67.21%
S	337	ASVFVQLRRKSDLETSEPKPF	PKA_group	15642694	LTP	1.00	MOD_PKA_1	-	IPT	0.42	1U3J	67.21%

Substrate:

Octamer binding transcription factor 1 (Transcription factor)

Seq-ID:

P14859 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6803426 SP1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, protein binding		transcription, negative regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	385	GLSRRRKKRTSIETNIRVALE	PKA_group	1684878	LTP	1.00	MOD_PKA_1	-	HOX	0.43	1HF0	90.16%

Substrate:

Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR (Early response protein NAK1) (TR3 orphan receptor))

Seq-ID:

P22829 [Rattus norvegicus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
zinc ion binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity	nucleus	transcription

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	340	GMVKEVVRTDSLKGRRGRLPS	PKA_group	8227042	LTP	1.00		-	-	0.49	1CIT	104.92%
S	350	SLKGRRGRLPSKPKQPPDASP	PKA_group	8227042	LTP	1.00		-	-	0.78	1CIT	100.82%

Substrate:

PCTAIRE1 (Serine/threonine-protein kinase PCTAIRE-1)

Seq-ID:

Q00536 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cyclin-dependent protein kinase activity,