Substrate: A-kinase anchoring protein. (kinase activity, Rho guanyl-nucleotide exchange factor activity)
Seq-ID: Q12802 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
cAMP-dependent protein kinase activity,
metal ion binding,
signal transducer activity,
protein binding		 membrane fraction,
cytosol,
nucleus,
membrane		 induction of apoptosis by extracellular signals,
apoptosis,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 393 VEPAPIVDSGTVSDQDSCLQS - 18669648
HTP
 - - -
0.71
 - medium
S 395 PAPIVDSGTVSDQDSCLQSLP - 18669648
HTP
 - - -
0.65
 - medium
T 784 VPDQAVISDSTFSLANSPGSE - 18669648
HTP
 - - -
0.72
 - medium
S 790 ISDSTFSLANSPGSESVTKDD - 18669648
HTP
 - - -
0.73
 - medium
S 793 STFSLANSPGSESVTKDDALS - 18669648
HTP
 - - -
0.70
 - medium
T 797 LANSPGSESVTKDDALSFVPS - 18669648
HTP
 - - -
0.73
 - medium
T 815 VPSQKEKGTATPELHTATDYR - 18669648
HTP
 - - -
0.82
 - medium
S 983 AKDKALQLSNSPGASSAFLKA - 16964243
HTP
 - - -
0.51
 - medium
S 983 AKDKALQLSNSPGASSAFLKA - 18669648
HTP
 - - -
0.51
 - medium
T 1170 GKLEGADHSCTMGDAEEAQID - 18669648
HTP
 - - -
0.74
 - medium
S 1411 DAASLLASKQSPECENFLDVG - 18669648
HTP
 - - -
0.43
 - medium
S 1492 DRHSSHGSDVSLSQILKPNRS - 18669648
HTP
 - - -
0.69
 - medium
S 1559 SVLRSSMRSLSPFRRHSWGPG - 17081983
HTP
 - - -
0.53
 - medium
S 1559 SVLRSSMRSLSPFRRHSWGPG - 18669648
HTP
 - - -
0.53
 - medium
S 1565 MRSLSPFRRHSWGPGKNAASD PKA_group 15229649
LTP
 - MOD_PKA_1
 - -
0.66
 - medium
S 1565 MRSLSPFRRHSWGPGKNAASD - 17081983
HTP
 - MOD_PKA_1
 - -
0.66
 - medium
S 1600 VVRRPPIHRRSFSLEGLTGGA - 18669648
HTP
 - - -
0.57
 - medium
S 1602 RRPPIHRRSFSLEGLTGGAGV - 18669648
HTP
 - - -
0.60
 - medium
S 1645 SGEERVDSLVSLSEEDLESDQ - 18669648
HTP
 - - -
0.61
 - medium
S 1647 EERVDSLVSLSEEDLESDQRE - 18669648
HTP
 - - -
0.62
 - medium
S 1750 KSGTKVSRTFSYIKNKMSSSK - 18669648
HTP
 - - -
0.45
 - medium
S 1876 KPSQPKERPRSAVLLVDETAT - 18669648
HTP
 - - -
0.69
 - medium
S 1929 MSNTWKFLSHSTDSLNKISKV - 17081983
HTP
 - - -
0.41
 - medium
S 1929 MSNTWKFLSHSTDSLNKISKV - 18669648
HTP
 - - -
0.41
 - medium
T 1930 SNTWKFLSHSTDSLNKISKVN - 18669648
HTP
 - - -
0.40
 - medium
S 1932 TWKFLSHSTDSLNKISKVNES - 17081983
HTP
 - - -
0.42
 - medium
S 1932 TWKFLSHSTDSLNKISKVNES - 18669648
HTP
 - - -
0.42
 - medium
T 1943 LNKISKVNESTESLTDEGVGT - 18669648
HTP
 - - -
0.59
 - medium
T 1947 SKVNESTESLTDEGVGTDMNE - 18669648
HTP
 - - -
0.67
 - medium
S 2345 LNRDEDEGIPSENEEEKKMLD - 17081983
HTP
 - - COIL
0.78
 - medium
S 2398 ECSTPLPEDCSPTHSPRVLFR - 18669648
HTP
 - - -
0.70
 - medium
T 2400 STPLPEDCSPTHSPRVLFRSN - 18669648
HTP
 - - -
0.72
 - medium
S 2402 PLPEDCSPTHSPRVLFRSNTE - 18669648
HTP
 - - -
0.72
 - medium
S 2561 LVLSERALTRSLSRPSSLIEQ - 18669648
HTP
 - - -
0.47
 - medium
S 2563 LSERALTRSLSRPSSLIEQEK - 18669648
HTP
 - - -
0.50
 - medium
S 2567 ALTRSLSRPSSLIEQEKQRSL - 18669648
HTP
 - - -
0.56
 - medium
S 2703 KLMRIPSFFPSPEEPPSPSAP - 18669648
HTP
 - - -
0.89
 - medium
S 2709 SFFPSPEEPPSPSAPSIAKSG - 18669648
HTP
 - - -
0.90
 - medium
S 2728 SGSLDSELSVSPKRNSISRTH - 16964243
HTP
 - - -
0.77
 - medium
S 2728 SGSLDSELSVSPKRNSISRTH - 18669648
HTP
 - - -
0.77
 - medium
S 2733 SELSVSPKRNSISRTHKDKGP PKA_group 15383279
LTP
 - MOD_PKA_1
 - -
0.79
 - medium

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