| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| Endocrine transmitter regulatory protein |
neurexin binding |
neurexin binding,
Rab GTPase binding,
phospholipid binding,
zinc ion binding,
transporter activity |
synaptic vesicle,
extrinsic to membrane |
intracellular protein transport,
exocytosis |
| LAT |
Adaptor molecule involved in the TCR signal pathway |
SH3/SH2 adaptor activity,
receptor signaling protein activity |
immunological synapse,
integral to membrane,
membrane raft,
integral to plasma membrane |
calcium-mediated signaling,
cellular defense response,
inflammatory response,
regulation of T cell activation,
transmembrane receptor protein tyrosine kinase signaling pathway,
integrin-mediated signaling pathway,
gene expression,
mast cell degranulation,
Ras protein signal transduction |
| cAMP-dependent protein kinase type II-alpha regulatory subunit |
cAMP-dependent protein kinase type II-alpha regulatory chain |
kinase activity,
cAMP binding,
cAMP-dependent protein kinase regulator activity |
cAMP-dependent protein kinase complex,
cytosol,
membrane fraction |
intracellular signaling pathway,
regulation of protein amino acid phosphorylation,
signal transduction,
activation of protein kinase A activity,
hormone-mediated signaling pathway |
| cAMP-dependent protein kinase type II-beta regulatory subunit |
cAMP-dependent protein kinase type II-beta regulatory chain |
cAMP binding,
cAMP-dependent protein kinase regulator activity |
cAMP-dependent protein kinase complex,
cytosol |
intracellular signaling pathway,
fatty acid metabolic process,
regulation of protein amino acid phosphorylation,
cell proliferation,
protein amino acid phosphorylation,
organ morphogenesis,
learning,
signal transduction,
activation of protein kinase A activity,
hormone-mediated signaling pathway |
| Coagulation factor IX |
coagulation factor IX precursor (EC 3.4.21.22) (christmas factor) (from PhosphoBase) |
serine-type endopeptidase activity,
calcium ion binding |
plasma membrane,
extracellular region |
blood coagulation, extrinsic pathway,
proteolysis |
| Ras-related protein Rab-4A |
ras-related protein Rab-4A (from PhosphoBase) |
GDP binding,
GTP binding,
GTPase activity |
|
small GTPase mediated signal transduction |
| Phosphorylase b kinase beta regulatory chain |
phosphorylase b kinase beta regulatory chain (from PhosphoBase) |
calmodulin binding,
glucan 1,4-alpha-glucosidase activity |
plasma membrane |
glycogen metabolic process |
| Myosin regulatory light chain 2, smooth muscle |
myosin regulatory light chain 2, smooth muscle major isoform (from PhosphoBase) |
calcium ion binding,
motor activity,
protein binding |
myosin complex |
|
| cAMP-dependent protein kinase type I-alpha regulatory subunit |
cAMP-dependent protein kinase, type I-alpha regulatory chain (from PhosphoBase) |
cAMP binding,
cAMP-dependent protein kinase regulator activity,
protein binding |
cAMP-dependent protein kinase complex,
cytoplasm,
cytosol,
neuromuscular junction |
intracellular signaling pathway,
mesoderm formation,
regulation of protein amino acid phosphorylation,
cell proliferation,
protein amino acid phosphorylation,
regulation of transcription from RNA polymerase II promoter,
signal transduction,
activation of protein kinase A activity,
hormone-mediated signaling pathway |
| Ras-related protein Rap-1b |
ras-related protein rap-1b (GTP-binding protein smg p21b) (from PhosphoBase) |
GDP binding,
GTP binding,
GTPase activity,
protein binding |
plasma membrane,
cytosol |
|
| cAMP-dependent protein kinase regulatory subunit |
cAMP-dependent protein kinase regulatory chain (from PhosphoBase) |
identical protein binding,
cAMP binding,
cAMP-dependent protein kinase regulator activity,
cAMP-dependent protein kinase inhibitor activity |
plasma membrane,
cAMP-dependent protein kinase complex,
cytoplasm,
nucleus |
negative regulation of Ras protein signal transduction,
regulation of protein amino acid phosphorylation,
signal transduction |
| Myosin regulatory light chain 2, skeletal muscle |
myosin regulatory light chain 2, skeletal muscle isoform (MLC-2) (from PhosphoBase) |
calcium ion binding,
structural constituent of muscle,
motor activity |
myosin complex |
skeletal muscle tissue development |
| Coagulation factor V |
Coagulation factor V |
copper ion binding,
oxidoreductase activity |
plasma membrane,
extracellular region,
platelet alpha granule lumen |
oxidation reduction,
blood coagulation,
cell adhesion |
| Regulator of G-protein signaling 10, isoform a |
GTPase activating protein |
signal transducer activity,
protein binding |
|
negative regulation of signal transduction |
| Adenylate cyclase 3 |
Adenylate cyclase |
adenylate cyclase activity,
metal ion binding,
ATP binding,
calmodulin binding |
plasma membrane,
cytoplasm,
integral to membrane,
integral to plasma membrane |
sensory perception of smell,
inhibition of adenylate cyclase activity by G-protein signaling pathway,
response to stimulus,
activation of protein kinase A activity,
activation of adenylate cyclase activity,
activation of adenylate cyclase activity by G-protein signaling pathway,
hormone-mediated signaling pathway |
| Protein zero related protein |
Immunoglobulin |
structural molecule activity,
protein binding |
integral to plasma membrane |
cell-cell signaling,
transmembrane receptor protein tyrosine kinase signaling pathway |
| Clathrin light polypeptide B |
Structural protein |
structural molecule activity,
protein binding |
clathrin coat of trans-Golgi network vesicle,
clathrin coat of coated pit |
vesicle-mediated transport,
intracellular protein transport |
| Ras related protein 1A |
GTPase |
GTP binding,
GTPase activity |
plasma membrane,
cytosol |
|
| Ras-related protein |
GTPase |
GDP binding,
GTP binding,
GTPase activity,
protein binding |
plasma membrane,
intracellular |
Ras protein signal transduction |
| Parathyroid hormone related protein |
Peptide hormone |
hormone activity |
cytoplasm,
extracellular space,
nucleus |
epidermis development,
negative regulation of cell proliferation,
cell-cell signaling,
regulation of gene expression,
cAMP metabolic process,
positive regulation of cAMP biosynthetic process,
positive regulation of cell proliferation,
skeletal system development,
female pregnancy,
negative regulation of chondrocyte differentiation,
activation of adenylate cyclase activity by G-protein signaling pathway |
| Coagulation Factor III |
Coagulation factor |
cell surface binding,
protease binding,
phospholipid binding |
integral to membrane,
intrinsic to external side of plasma membrane,
extracellular matrix,
extracellular space |
positive regulation of endothelial cell proliferation,
activation of caspase activity,
positive regulation of angiogenesis,
blood coagulation, extrinsic pathway,
positive regulation of platelet-derived growth factor receptor signaling pathway,
positive regulation of positive chemotaxis,
anti-apoptosis,
positive regulation of protein kinase B signaling cascade,
activation of blood coagulation via clotting cascade,
activation of plasma proteins involved in acute inflammatory response |
| Ras-related protein Rab-5B |
GTPase |
GTP binding,
GTPase activity,
GTP-dependent protein binding |
plasma membrane,
early endosome membrane,
melanosome,
membrane fraction |
protein transport,
small GTPase mediated signal transduction |
| Phosphorylase b kinase alpha regulatory chain, skeletal muscle isoform |
Enzyme: Phosphorylase |
calmodulin binding,
phosphorylase kinase activity,
glucan 1,4-alpha-glucosidase activity |
plasma membrane,
cytoplasm,
intracellular membrane-bounded organelle |
glycogen metabolic process |
| Clathrin heavy chain 1 |
Structural protein |
structural molecule activity,
protein binding |
spindle,
melanosome,
clathrin coat of trans-Golgi network vesicle,
clathrin coat of coated pit,
mitochondrion |
vesicle-mediated transport,
intracellular protein transport,
mitosis,
receptor internalization,
post-Golgi vesicle-mediated transport,
transferrin transport |
| cAMP response element modulator |
Transcription factor |
protein dimerization activity,
sequence-specific DNA binding,
cAMP response element binding protein binding,
sequence-specific DNA binding transcription factor activity,
protein binding |
transcription factor complex |
spermatogenesis,
regulation of transcription, DNA-dependent,
glycosphingolipid metabolic process,
transcription,
signal transduction,
cell differentiation,
multicellular organismal development |
| Metal-regulatory transcription factor |
Transcription factor |
transcription coactivator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity |
nucleus |
transcription |
| Protein phosphatase 1, regulatory subunit 3A |
Serine/threonine phosphatase |
|
integral to membrane |
glycogen metabolic process |
| Vaccinia related kinase 1 |
Serine/threonine kinase |
ATP binding,
protein serine/threonine kinase activity,
protein binding |
cytoplasm,
nucleolus |
|
| JAW1-related protein MRVI1A long isoform |
Unclassified |
|
sarcoplasmic reticulum,
integral to membrane,
endoplasmic reticulum membrane,
perinuclear region of cytoplasm |
|
| NF-kappa-B essential modulator |
Serine/threonine kinase |
metal ion binding,
signal transducer activity,
protein domain specific binding |
nucleus |
activation of NF-kappaB-inducing kinase activity,
B cell homeostasis,
interspecies interaction between organisms,
T cell receptor signaling pathway,
induction of apoptosis,
transcription,
immune response,
positive regulation of NF-kappaB transcription factor activity,
response to DNA damage stimulus |
| Hepatoma up-regulated protein |
Unclassified |
phosphoprotein phosphatase activity,
protein binding |
nucleus,
spindle pole centrosome |
positive regulation of mitotic metaphase/anaphase transition,
cell-cell signaling,
cell proliferation,
mitotic chromosome movement towards spindle pole |
| Megakaryocyte stimulating factor |
Cell junction protein |
scavenger receptor activity,
polysaccharide binding,
protein binding |
extracellular region |
cell proliferation,
immune response |
| Serum inhibited-related protein |
Unclassified |
|
|
|
| Calcium-regulated heat stable protein 1 |
Calcium binding protein |
DNA binding,
phosphatase binding,
protein binding |
cytoplasm,
cytosol |
intracellular signaling pathway,
calcium-mediated signaling,
regulation of transcription, DNA-dependent |
| Adenylate cyclase 6 |
Adenylate cyclase |
metal ion binding,
ATP binding |
integral to membrane |
inhibition of adenylate cyclase activity by G-protein signaling pathway,
activation of protein kinase A activity,
activation of adenylate cyclase activity by G-protein signaling pathway,
hormone-mediated signaling pathway |
| Myeloid translocation related protein 1 |
Transcription factor |
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
protein binding |
nucleus |
regulation of transcription, DNA-dependent |
| Transcriptional regulator ERG |
Transcription factor |
signal transducer activity,
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity,
protein binding |
cytoplasm,
ribonucleoprotein complex,
nucleus |
regulation of transcription, DNA-dependent,
cell proliferation,
protein amino acid phosphorylation,
transcription,
multicellular organismal development |
| Eukaryotic translation elongation factor 2 |
Translation regulatory protein |
GTP binding,
GTPase activity,
translation elongation factor activity,
protein binding |
cytoplasm,
ribonucleoprotein complex |
|
| Fos-related antigen 2 |
Transcription factor |
protein dimerization activity,
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity |
nucleus |
regulation of transcription, DNA-dependent,
cell death,
regulation of transcription from RNA polymerase II promoter |
| Regulator of chromosome condensation |
Guanine nucleotide exchange factor |
histone binding,
nucleosomal DNA binding,
Ran guanyl-nucleotide exchange factor activity |
cytoplasm,
nuclear chromatin,
condensed nuclear chromosome |
regulation of mitosis,
mitosis,
spindle assembly,
cell division,
regulation of S phase of mitotic cell cycle,
chromosome segregation,
G1/S transition of mitotic cell cycle,
mitotic spindle organization |
| Regulatory factor X 1 |
Transcription regulatory protein |
RNA polymerase II transcription factor activity, enhancer binding,
protein binding |
nucleus |
regulation of transcription, DNA-dependent,
transcription,
immune response |
| Cleavage and polyadenylation specificity factor 1 |
RNA binding protein |
mRNA 3`-UTR binding,
protein binding |
mRNA cleavage and polyadenylation specificity factor complex |
mRNA polyadenylation,
RNA splicing,
mRNA cleavage |
| ADP ribosylation factor GTPase activating protein 1 |
GTPase activating protein |
ARF GTPase activator activity,
zinc ion binding |
Golgi membrane |
vesicle-mediated transport,
retrograde vesicle-mediated transport, Golgi to ER,
protein transport,
COPI coating of Golgi vesicle,
regulation of ARF GTPase activity |
| OSBP related protein 11 |
Transport/cargo protein |
|
|
lipid transport,
steroid metabolic process |
| Cleavage and polyadenylation specificity factor 2 |
RNA binding protein |
RNA binding,
hydrolase activity,
protein binding |
nucleus |
histone mRNA 3`-end processing,
RNA splicing |
| La-related protein 4 |
Unclassified |
RNA binding |
|
|
| 26S protease regulatory subunit 4 |
26S protease regulatory subunit 4 |
ATPase activity,
ATP binding,
protein binding |
cytoplasm,
proteasome complex,
nucleus |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Protein phosphatase 1, regulatory subunit 12A |
Myosin phosphatase target subunit 1 |
phosphoprotein phosphatase activity,
signal transducer activity,
protein binding |
cytoplasm |
regulation of nucleocytoplasmic transport,
protein amino acid dephosphorylation |
| Latrophilin-1 precursor |
Unclassified |
G-protein coupled receptor activity,
sugar binding |
plasma membrane,
integral to membrane |
neuropeptide signaling pathway |
| Cyclic AMP-regulated phosphoprotein, 21 kD, isoform 1 |
Unclassified |
nucleic acid binding |
cytoplasm |
|
| Clathrin coat assembly protein AP180 |
Clathrin coat associated protein AP180 |
clathrin heavy chain binding,
phosphatidylinositol binding |
AP-2 adaptor complex |
clathrin coat assembly,
neurotransmitter secretion |
| Cell death regulator Aven |
|
protein binding |
membrane fraction,
intracellular,
membrane,
endomembrane system |
apoptosis,
anti-apoptosis |
| Myosin regulatory light chain 2, smooth muscle isoform |
|
calcium ion binding,
structural constituent of muscle,
motor activity |
myosin complex,
muscle myosin complex |
regulation of muscle contraction,
muscle contraction |
| NAP-1 related protein |
Nucleosome assembly protein 1-like 1 |
protein binding |
chromatin assembly complex,
melanosome,
nucleus |
DNA replication,
positive regulation of cell proliferation,
nucleosome assembly |
| 26S proteasome non-ATPase regulatory subunit 4 |
proteasome subunit |
protein binding |
proteasome complex |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| A6 related protein |
Unclassified |
ATP binding,
actin binding |
cytoskeleton,
perinuclear region of cytoplasm |
|
| Adenylate cyclase type IX |
Adenylate cyclase activity |
adenylate cyclase activity,
metal ion binding,
ATP binding |
plasma membrane,
integral to membrane,
integral to plasma membrane |
inhibition of adenylate cyclase activity by G-protein signaling pathway,
activation of protein kinase A activity,
activation of adenylate cyclase activity,
activation of adenylate cyclase activity by G-protein signaling pathway,
hormone-mediated signaling pathway |
| ADP-ribosylation factor GTPase-activating protein 3 |
GTPase activating protein |
ARF GTPase activator activity,
protein transporter activity,
zinc ion binding |
cytosol,
Golgi membrane |
vesicle-mediated transport,
intracellular protein transport,
protein secretion,
regulation of ARF GTPase activity |
| Cleavage stimulation factor, 50 kDa subunit |
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs |
RNA binding,
protein binding |
nucleus |
mRNA polyadenylation,
RNA splicing,
mRNA cleavage |
| Cytoplasmic polyadenylation element binding protein |
Unclassified |
RNA binding,
protein binding |
ribonucleoprotein complex,
protein complex,
spindle pole,
microtubule organizing center,
membrane |
regulation of translation,
mRNA processing |
| Dual specificity tyrosine-phosphorylation regulated kinase 3 |
Ser/Thr protein kinase family |
ATP binding,
magnesium ion binding,
protein serine/threonine kinase activity,
protein tyrosine kinase activity,
protein binding |
nucleus |
protein amino acid phosphorylation,
erythrocyte differentiation |
| Eukaryotic translation initiation factor 1 |
Translation initiation factor activity |
translation initiation factor activity |
cytoplasm |
response to stress |
| Eukaryotic translation initiation factor 3 subunit 6 |
Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA |
translation initiation factor activity,
protein N-terminus binding |
cytosol,
eukaryotic translation initiation factor 3 complex,
nucleoplasm |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,
negative regulation of translational initiation |
| Eukaryotic translation initiation factor 4H |
Unclassified |
translation initiation factor activity,
RNA binding,
nucleotide binding,
protein binding |
cytosol,
perinuclear region of cytoplasm,
eukaryotic translation initiation factor 4F complex |
interspecies interaction between organisms |
| Fragile X mental retardation syndrome-related protein 1 |
RNA-binding protein |
mRNA 3`-UTR binding,
G-quadruplex RNA binding,
protein binding |
costamere,
polysome,
nucleolus,
nucleus |
apoptosis,
negative regulation of translation,
muscle organ development,
cell differentiation |
| Malate dehydrogenase, mitochondrial precursor |
LDH/MDH superfamily. MDH type 1 family |
L-malate dehydrogenase activity |
mitochondrial matrix |
tricarboxylic acid cycle,
oxidation reduction,
glycolysis,
malate metabolic process |
| Monocarboxylate transporter 1 |
Proton-linked monocarboxylate transporter |
symporter activity,
mevalonate transmembrane transporter activity,
secondary active monocarboxylate transmembrane transporter activity,
protein binding |
plasma membrane,
integral to membrane,
membrane fraction,
mitochondrion |
organic anion transport |
| Phosphatidylinositol 3-kinase regulatory beta subunit |
Binds to activated (phosphorylated) protein-tyrosine |
phosphoinositide 3-kinase regulator activity,
protein binding |
phosphoinositide 3-kinase complex |
negative regulation of anti-apoptosis,
signal transduction,
insulin receptor signaling pathway |
| Polyadenylate-binding protein 1 |
Binds the poly(A) tail of mRNA |
translation activator activity,
poly(A) RNA binding,
nucleotide binding,
protein C-terminus binding |
cytosol,
spliceosomal complex |
mRNA stabilization,
mRNA polyadenylation,
RNA splicing |
| Protein phosphatase 1 regulatory subunit 14B |
Inhibitor of PPP1CA |
phosphoprotein phosphatase inhibitor activity,
protein binding |
cytoplasm |
regulation of phosphorylation |
| Protein phosphatase 1 regulatory subunit 14C |
Inhibitor of PPP1CA |
protein binding |
cytoplasm,
membrane |
regulation of phosphorylation |
| Ras-related protein Rab-7 |
Small GTPase superfamily |
GTP binding,
GTPase activity,
protein binding |
melanosome,
Golgi apparatus,
phagocytic vesicle,
late endosome,
lysosome |
intracellular protein transport,
endocytosis,
protein transport,
small GTPase mediated signal transduction |
| Regulating synaptic membrane exocytosis protein 1 |
Transport/cargo protein |
Rab GTPase binding,
zinc ion binding |
cell junction,
presynaptic membrane |
visual perception,
intracellular protein transport,
synaptic vesicle exocytosis,
response to stimulus,
cellular membrane fusion,
exocytosis,
positive regulation of synaptic vesicle fusion to presynaptic membrane,
protein complex assembly,
regulated secretory pathway,
neurotransmitter transport,
calcium ion-dependent exocytosis,
regulation of long-term neuronal synaptic plasticity |
| Serine/threonine-protein kinase LATS2 |
Ser/Thr protein kinase family |
metal ion binding,
ATP binding,
protein serine/threonine kinase activity,
protein binding |
spindle pole,
microtubule organizing center,
nucleus |
negative regulation of cyclin-dependent protein kinase activity,
negative regulation of canonical Wnt receptor signaling pathway,
mitosis,
protein amino acid phosphorylation,
cell division,
G1/S transition of mitotic cell cycle,
hippo signaling cascade,
hormone-mediated signaling pathway,
intracellular protein kinase cascade |
| SV2 RELATED PROTEIN homolog |
Unclassified |
ion transmembrane transporter activity |
cell junction,
integral to membrane,
synaptic vesicle membrane |
|
| Translationally controlled tumor protein |
TCTP family |
calcium ion binding,
protein binding |
multivesicular body,
extracellular space |
calcium ion transport,
anti-apoptosis,
cellular calcium ion homeostasis,
response to virus |
| LATS1 |
serine/threonine kinase |
ATP binding,
magnesium ion binding,
protein serine/threonine kinase activity,
protein kinase binding |
spindle pole,
microtubule organizing center |
negative regulation of cyclin-dependent protein kinase activity,
cytoplasmic sequestering of protein,
positive regulation of peptidyl-serine phosphorylation,
negative regulation of canonical Wnt receptor signaling pathway,
mitosis,
sister chromatid segregation,
protein amino acid phosphorylation,
cell division,
regulation of actin filament polymerization,
hippo signaling cascade,
G2/M transition of mitotic cell cycle,
hormone-mediated signaling pathway |
| LAT2 |
protein binding, SH2 domain binding |
SH2 domain binding |
plasma membrane,
integral to membrane,
membrane raft |
calcium-mediated signaling,
B cell receptor signaling pathway,
mast cell degranulation,
B cell activation |
| PI-3-kinase-related kinase SMG-1 |
inositol or phosphatidylinositol kinase activity |
metal ion binding,
ATP binding,
protein serine/threonine kinase activity,
protein binding |
cytoplasm,
nucleus |
mRNA export from nucleus,
protein amino acid autophosphorylation,
phosphoinositide phosphorylation,
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,
DNA repair,
response to stress,
peptidyl-serine phosphorylation |
| Eukaryotic translation initiation factor 2-alpha kinase 4 |
eukaryotic translation initiation factor |
ATP binding,
eukaryotic translation initiation factor 2alpha kinase activity,
protein binding |
cytosolic ribosome |
cellular response to starvation,
regulation of translational initiation in response to stress,
endoplasmic reticulum unfolded protein response,
protein amino acid phosphorylation,
negative regulation of translation |
| Actin-related protein 8 |
unclassified |
transcription regulator activity,
protein binding |
cytoplasm,
cytoskeleton,
Ino80 complex |
chromatin remodeling |
| Adhesion-regulating molecule 1 precursor |
unclassified |
endopeptidase activator activity,
protease binding,
proteasome binding |
cytoplasm,
membrane fraction,
proteasome complex,
integral to plasma membrane,
nucleus |
proteasome assembly,
RNA elongation from RNA polymerase II promoter |
| Arsenite related gene 1 |
unclassified |
kinetochore binding,
protein binding |
outer kinetochore of condensed chromosome,
spindle pole,
microtubule organizing center,
nucleus |
protein localization to kinetochore,
mitotic metaphase plate congression,
cell division,
establishment of mitotic spindle orientation |
| Carbonic anhydrase-related protein 10 |
unclassified |
|
|
brain development |
| Clathrin heavy chain 2 |
signal transducer activity |
signal transducer activity,
structural molecule activity,
protein binding |
spindle,
clathrin coat of trans-Golgi network vesicle,
clathrin coat of coated pit,
trans-Golgi network |
anatomical structure morphogenesis,
intracellular protein transport,
mitosis,
receptor-mediated endocytosis,
positive regulation of glucose import |
| Interferon regulatory factor 2 binding protein 1 variant |
unclassified |
|
nucleus |
regulation of transcription,
transcription |
| Lung cancer metastasis-related protein |
protein binding |
RNA polymerase II transcription mediator activity |
|
transcription,
regulation of transcription from RNA polymerase II promoter |
| Mid-1-related chloride channel 1 |
chloride channel activity |
|
integral to membrane,
Golgi apparatus,
endoplasmic reticulum,
nucleus |
|
| Monocarboxylate transporter 4 |
monocarboxylic acid transporter activity |
symporter activity,
secondary active monocarboxylate transmembrane transporter activity |
plasma membrane,
integral to membrane,
membrane fraction,
integral to plasma membrane |
organic anion transport |
| Monocarboxylate transporter 7 |
monocarboxylic acid transporter activity |
symporter activity,
monocarboxylic acid transmembrane transporter activity |
membrane fraction,
integral to plasma membrane |
|
| Myotubularin-related protein 2 |
phosphatase activity |
protein tyrosine phosphatase activity,
inositol or phosphatidylinositol phosphatase activity,
protein tyrosine/serine/threonine phosphatase activity |
nucleus |
protein amino acid dephosphorylation |
| Osteoclast-stimulating factor 1 |
protein binding |
identical protein binding,
SH3 domain binding |
cytoplasm |
ossification,
signal transduction |
| Ras-related protein Rab-8A |
unclassified |
GTP binding,
protein binding |
plasma membrane,
nonmotile primary cilium |
vesicle docking involved in exocytosis,
cilium assembly,
Golgi vesicle fusion to target membrane,
protein transport,
small GTPase mediated signal transduction |
| Ras-related protein Rab-9A |
GTPase activity |
GDP binding,
GTP binding,
GTPase activity,
protein binding |
plasma membrane,
endoplasmic reticulum membrane,
Golgi membrane,
late endosome,
lysosome |
protein transport,
small GTPase mediated signal transduction |
| Ras-related protein R-Ras2 |
protein binding |
GTP binding,
GTPase activity,
protein binding |
plasma membrane,
endoplasmic reticulum,
intracellular |
positive regulation of cell migration,
Ras protein signal transduction |
| Secreted frizzled-related protein 2 precursor |
unclassified |
fibronectin binding,
integrin binding |
extracellular matrix,
extracellular space |
positive regulation of cell adhesion mediated by integrin,
patterning of blood vessels,
sclerotome development,
positive regulation of cell growth,
negative regulation of cell proliferation,
positive regulation of anti-apoptosis,
positive regulation of apoptosis,
cell-cell signaling,
Wnt receptor signaling pathway,
positive regulation of angiogenesis,
negative regulation of cell migration,
dermatome development,
positive regulation of cell proliferation,
outflow tract morphogenesis,
hemopoietic stem cell proliferation,
negative regulation of cell growth,
negative regulation of peptidyl-tyrosine phosphorylation,
cardiac left ventricle morphogenesis,
regulation of stem cell division,
negative regulation of gene expression |
| Small ubiquitin-related modifier 1 precursor |
protein binding |
ubiquitin protein ligase binding |
cytoplasm,
nuclear pore,
nuclear membrane,
nuclear speck |
positive regulation of protein complex assembly,
negative regulation of transcription,
positive regulation of proteasomal ubiquitin-dependent protein catabolic process,
protein sumoylation,
negative regulation of transcription factor activity,
DNA repair,
regulation of protein localization |
| Adapter-related protein complex 3 beta 1 subunit |
unclassified |
protein transporter activity,
protein phosphatase binding |
membrane coat,
Golgi apparatus,
clathrin coated vesicle membrane,
trans-Golgi network |
positive regulation of NK T cell differentiation,
endocytosis,
blood coagulation,
antigen processing and presentation, exogenous lipid antigen via MHC class Ib,
protein targeting to lysosome,
zinc ion transport |
| Bcl-2-related proline-rich protein |
unclassified |
|
|
apoptosis |
| Cleavage stimulation factor, 64 kDa subunit |
protein binding |
RNA binding,
nucleotide binding,
protein binding |
nucleus |
mRNA polyadenylation,
RNA splicing,
mRNA cleavage |
| Eukaryotic translation initiation factor 4 gamma 3 |
protein binding |
translation initiation factor activity,
RNA binding,
RNA cap binding,
protein binding |
eukaryotic translation initiation factor 4F complex |
interspecies interaction between organisms,
RNA metabolic process |
| NMDA receptor regulated protein 1 |
binding |
N-acetyltransferase activity,
protein binding |
cytoplasm,
transcription factor complex,
perinuclear region of cytoplasm |
positive regulation of transcription, DNA-dependent,
N-terminal protein amino acid acetylation,
transcription,
angiogenesis,
cell differentiation |
| Oxysterol binding protein-related protein 9 |
unclassified |
|
|
|
| Phosphatase and actin regulator 2 |
unclassified |
phosphoprotein phosphatase inhibitor activity,
actin binding |
|
|
| Regulator of nonsense transcripts 1 |
ATP-dependent RNA helicase activity |
DNA binding,
chromatin binding,
RNA binding,
ATP binding,
ATP-dependent RNA helicase activity,
zinc ion binding,
protein binding |
chromatin,
cytoplasmic mRNA processing body |
mRNA export from nucleus,
DNA replication,
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,
histone mRNA catabolic process,
DNA repair,
regulation of translational termination,
cell cycle |
| Apoptosis stimulating of p53 protein 2 |
NF-kappaB binding |
SH3/SH2 adaptor activity,
SH3 domain binding,
NF-kappaB binding |
perinuclear region of cytoplasm,
nucleus |
embryo development ending in birth or egg hatching,
apoptosis,
heart development,
induction of apoptosis,
central nervous system development,
cell cycle,
response to ionizing radiation,
negative regulation of cell cycle |
| SR-related CTD associated factor 6 |
RNA binding |
RNA binding |
perinuclear region of cytoplasm,
endoplasmic reticulum |
negative regulation of cell proliferation,
nervous system development,
RNA processing,
cellular calcium ion homeostasis |
| TATA element modulatory factor |
transcription factor activity |
DNA binding,
RNA polymerase II transcription factor activity,
transcription cofactor activity |
Golgi membrane,
nucleus |
regulation of transcription, DNA-dependent,
transcription from RNA polymerase II promoter |
| Transducer of regulated CREB protein 3 |
unclassified |
|
cytoplasm,
nucleus |
regulation of transcription,
interspecies interaction between organisms,
transcription |
| U2 snRNP auxiliary factor 35 kDa subunit related-protein 2 |
unclassified |
RNA binding,
nucleotide binding,
zinc ion binding |
U12-type spliceosomal complex |
RNA splicing |
| Latrophilin-3 |
Unclassified |
G-protein coupled receptor activity,
sugar binding |
plasma membrane,
integral to membrane |
neuropeptide signaling pathway |
| Runt-related transcription factor 2 |
|
specific transcriptional repressor activity,
RNA polymerase II transcription factor activity,
chromatin binding,
ATP binding,
promoter binding,
transcription activator activity,
sequence-specific DNA binding transcription factor activity,
protein binding |
cytoplasm,
transcription factor complex,
nucleus |
chondrocyte development,
regulation of fibroblast growth factor receptor signaling pathway,
osteoblast fate commitment,
osteoblast differentiation,
cell maturation,
negative regulation of transcription,
negative regulation of smoothened signaling pathway,
positive regulation of chondrocyte differentiation,
odontogenesis of dentine-containing tooth,
regulation of transcription, DNA-dependent,
positive regulation of osteoblast differentiation,
regulation of odontogenesis of dentine-containing tooth,
positive regulation of cell proliferation,
transcription,
endochondral ossification,
positive regulation of transcription from RNA polymerase II promoter |
| Density-regulated protein |
|
translation initiation factor activity,
protein binding |
|
|
| Rho-related BTB domain-containing protein 1. |
|
GTP binding,
protein binding |
intracellular |
small GTPase mediated signal transduction |
| Ras-related protein Rab-6A |
|
GTP binding,
GTPase activity |
Golgi membrane |
vesicle-mediated transport,
intracellular protein transport,
small GTPase mediated signal transduction |
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 |
|
p53 binding |
npBAF complex,
nBAF complex,
SWI/SNF complex,
nucleolus,
nucleoplasm,
nuclear chromosome |
positive regulation of gene-specific transcription from RNA polymerase II promoter,
chromatin remodeling,
DNA integration,
interspecies interaction between organisms,
nervous system development,
transcription,
positive regulation of transcription factor activity,
cell cycle,
retroviral genome replication |
| NMDA receptor-regulated protein 2. |
|
|
nucleus |
|
| CREB-regulated transcription coactivator 1 |
|
cAMP response element binding protein binding |
cytoplasm,
nucleus |
interspecies interaction between organisms,
transcription,
positive regulation of transcription from RNA polymerase II promoter |
| PRKC apoptosis WT1 regulator protein |
|
transcription corepressor activity,
enzyme binding,
leucine zipper domain binding |
plasma membrane,
cytoplasm,
nucleus |
apoptosis,
positive regulation of apoptosis,
transcription,
negative regulation of transcription from RNA polymerase II promoter |
| Dihydropyrimidinase-related protein 5 |
|
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
cytoplasm |
axon guidance,
signal transduction |
| Oxysterol-binding protein-related protein 6 |
|
|
|
lipid transport,
steroid metabolic process |
| Regulating synaptic membrane exocytosis protein 4 |
|
|
cell junction,
synapse |
exocytosis,
neurotransmitter transport |
| Secretion-regulating guanine nucleotide exchange factor |
|
Ran guanyl-nucleotide exchange factor activity,
protein binding |
cytoplasm,
nucleus |
negative regulation of protein secretion,
signal transduction |
| ADP-ribosylation factor-binding protein GGA1 |
|
protein binding |
clathrin adaptor complex,
Golgi apparatus part,
endosome membrane |
vesicle-mediated transport,
intracellular protein transport |
| ADP-ribosylation factor-like protein 2-binding protein |
|
small GTPase regulator activity |
mitochondrial intermembrane space,
microtubule organizing center |
signal transduction |
| Actin-related protein 5 |
|
transcription regulator activity,
protein binding |
Ino80 complex |
chromatin remodeling,
transcription |
| Adenylate kinase 2, mitochondrial |
|
ATP binding,
adenylate kinase activity,
protein binding |
mitochondrial intermembrane space |
|
| cAMP-dependent protein kinase type II regulatory subunit |
|
cAMP binding,
cAMP-dependent protein kinase regulator activity,
protein binding |
cAMP-dependent protein kinase complex,
cytoplasm |
behavioral response to ethanol,
regulation of protein amino acid phosphorylation,
axon guidance,
signal transduction,
locomotor rhythm,
behavioral response to cocaine |
| Guanylate kinase-associated protein mars |
|
protein binding |
plasma membrane,
spindle,
cytoplasm,
nucleoplasm |
kinetochore assembly,
cell-cell signaling,
M phase of mitotic cell cycle,
regulation of mitotic cell cycle,
spindle stabilization,
chromosome segregation |
| JmjC domain-containing histone demethylation protein 1 |
|
DNA binding,
histone demethylase activity (H3-K36 specific),
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen,
zinc ion binding,
protein binding |
nucleus |
oxidation reduction,
regulation of transcription,
transcription |
| La-related protein CG11505 |
|
RNA binding,
protein binding |
|
|
| La-related protein dlarp |
|
RNA binding,
protein binding |
cytosol |
mitochondrion inheritance,
spindle assembly involved in male meiosis,
syncytial blastoderm mitotic cell cycle,
salivary gland cell autophagic cell death |
| Lateral signaling target protein 2 homolog |
|
zinc ion binding |
|
|
| Protein anoxia up-regulated |
|
protein binding |
|
response to oxidative stress |
| Regulator of telomere elongation helicase 1 homolog |
|
DNA binding,
iron-sulfur cluster binding,
metal ion binding,
ATP binding,
ATP-dependent DNA helicase activity |
nucleus |
regulation of double-strand break repair via homologous recombination,
DNA repair |
| Sphingomyelin synthase-related 1 |
|
|
integral to membrane |
sphingomyelin biosynthetic process |
| Translationally-controlled tumor protein homolog |
|
guanyl-nucleotide exchange factor activity,
calcium ion binding,
protein binding |
cytoplasm |
positive regulation of cell size,
positive regulation of multicellular organism growth |
| Cyclin-dependent kinases regulatory subunit 2 |
|
|
|
|
