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NameDescriptionMolecular FunctionCellular ComponentBiological Process
Lilrb3 Unclassified receptor activity cytokine-mediated signaling pathway,
B cell homeostasis,
B cell mediated immunity,
myeloid dendritic cell differentiation
IL10RB Histocompatibility receptor receptor activity integral to membrane blood coagulation
Phosphoenolpyruvate carboxylase 3 phosphoenolpyruvate carboxylase 3 (EC 4.1.1.31) (CP46) (from PhosphoBase) phosphoenolpyruvate carboxylase activity cytoplasm tricarboxylic acid cycle,
photosynthesis,
carbon fixation
ErbB2 Receptor tyrosine kinase epidermal growth factor receptor activity,
ErbB-3 class receptor binding,
DNA binding,
identical protein binding,
ATP binding,
protein heterodimerization activity,
transmembrane receptor protein tyrosine kinase activity,
protein C-terminus binding,
receptor signaling protein tyrosine kinase activity,
protein phosphatase binding
receptor complex,
integral to membrane,
perinuclear region of cytoplasm,
apical plasma membrane,
nucleus
negative regulation of immature T cell proliferation in the thymus,
regulation of transcription,
heart development,
protein amino acid autophosphorylation,
transmembrane receptor protein tyrosine kinase signaling pathway,
wound healing,
positive regulation of MAP kinase activity,
cell proliferation,
motor axon guidance,
regulation of angiogenesis,
transcription,
neuromuscular junction development,
myelination,
peripheral nervous system development,
phosphoinositide 3-kinase cascade,
phosphoinositide-mediated signaling,
positive regulation of cell adhesion,
positive regulation of epithelial cell proliferation
ErbB3 Receptor tyrosine kinase ATP binding,
protein heterodimerization activity,
transmembrane receptor protein tyrosine kinase activity,
receptor signaling protein tyrosine kinase activity,
protein homodimerization activity,
protein tyrosine kinase activator activity,
growth factor binding
receptor complex,
basolateral plasma membrane,
integral to plasma membrane,
extracellular space
positive regulation of phosphoinositide 3-kinase cascade,
heart development,
negative regulation of secretion,
transmembrane receptor protein tyrosine kinase signaling pathway,
cranial nerve development,
wound healing,
Schwann cell differentiation,
protein amino acid phosphorylation,
negative regulation of signal transduction,
phosphoinositide 3-kinase cascade,
neuron apoptosis,
negative regulation of neuron apoptosis,
regulation of cell proliferation,
negative regulation of cell adhesion
Ornithine decarboxylase ornithine decarboxylase (EC 4.1.1.17) (ODC) (from PhosphoBase) ornithine decarboxylase activity cytosol kidney development,
positive regulation of cell proliferation,
polyamine biosynthetic process
RB retinoblastoma-associated protein (pp110) (p105-RB) (RB) (from PhosphoBase) DNA binding,
androgen receptor binding,
kinase binding,
phosphoprotein binding,
transcription repressor activity,
ubiquitin protein ligase binding,
transcription factor binding,
transcription coactivator activity,
sequence-specific DNA binding transcription factor activity
spindle,
transcription factor complex,
Rb-E2F complex,
PML body,
chromatin,
SWI/SNF complex
enucleate erythrocyte differentiation,
mitotic cell cycle G1/S transition checkpoint,
regulation of transcription involved in G1/S phase of mitotic cell cycle,
negative regulation of cell proliferation,
cell cycle arrest,
G1 phase,
chromatin remodeling,
interspecies interaction between organisms,
negative regulation of transcription factor activity,
chromatin modification,
transcription,
cell division,
negative regulation of cell growth,
G1/S transition of mitotic cell cycle,
regulation of lipid kinase activity,
negative regulation of S phase of mitotic cell cycle,
myoblast differentiation,
striated muscle cell differentiation,
M phase,
androgen receptor signaling pathway,
Ras protein signal transduction,
positive regulation of transcription from RNA polymerase II promoter,
negative regulation of protein kinase activity,
negative regulation of transcription from RNA polymerase II promoter,
positive regulation of macrophage differentiation
Carbon catabolite derepressing protein kinase carbon catabolite derepressing protein kinase (EC 2.7.1.-) (from PhosphoBase) ATP binding,
AMP-activated protein kinase activity,
protein binding
fungal-type vacuole,
nuclear envelope lumen,
mitochondrion,
nuclear membrane,
AMP-activated protein kinase complex
invasive growth in response to glucose limitation,
carbohydrate metabolic process,
biofilm formation,
pseudohyphal growth,
protein amino acid phosphorylation,
positive regulation of gluconeogenesis,
signal transduction,
replicative cell aging,
negative regulation of translation,
cell adhesion,
cellular response to nitrogen starvation
Grb2 Adaptor molecule epidermal growth factor receptor binding,
insulin receptor substrate binding,
SH3/SH2 adaptor activity
cytosol,
Golgi apparatus
epidermal growth factor receptor signaling pathway,
cell-cell signaling,
interspecies interaction between organisms,
receptor internalization,
Ras protein signal transduction,
insulin receptor signaling pathway
Acetyl-CoA carboxylase 1 Enzyme: Carboxylase metal ion binding,
ATP binding,
biotin binding,
acetyl-CoA carboxylase activity,
biotin carboxylase activity,
protein binding
soluble fraction,
mitochondrion
response to drug,
fatty acid biosynthetic process,
tissue homeostasis,
multicellular organismal protein metabolic process,
response to organic cyclic substance,
acetyl-CoA metabolic process,
lipid homeostasis
Sodium bicarbonate cotransporter Membrane transport protein inorganic anion exchanger activity,
symporter activity,
sodium:bicarbonate symporter activity
basolateral plasma membrane,
integral to plasma membrane
regulation of pH,
sodium ion transport
Carboxy terminus of Hsp70-interacting protein Enzyme: Ligase Hsp90 protein binding,
kinase binding,
ubiquitin-ubiquitin ligase activity,
protein homodimerization activity,
TPR domain binding,
protein binding, bridging,
SMAD binding,
misfolded protein binding,
Hsp70 protein binding
cytoplasm,
nuclear inclusion body,
ubiquitin ligase complex,
ubiquitin conjugating enzyme complex
ubiquitin-dependent SMAD protein catabolic process,
protein maturation,
regulation of glucocorticoid metabolic process,
cellular response to misfolded protein,
positive regulation of proteasomal ubiquitin-dependent protein catabolic process,
misfolded or incompletely synthesized protein catabolic process,
positive regulation of cellular chaperone-mediated protein complex assembly,
protein autoubiquitination,
protein folding,
proteasomal ubiquitin-dependent protein catabolic process,
positive regulation of protein ubiquitination,
protein polyubiquitination
Erbin Adapter molecule structural constituent of cytoskeleton,
ErbB-2 class receptor binding,
integrin binding,
protein binding
cytoplasm,
hemidesmosome,
basement membrane,
nucleus
cell growth,
epidermal growth factor receptor signaling pathway,
establishment or maintenance of epithelial cell apical/basal polarity,
intermediate filament cytoskeleton organization,
protein targeting,
basal protein localization,
integrin-mediated signaling pathway,
cell cycle,
signal transduction,
cell adhesion
Sodium bicarbonate cotransporter 3 presumably ion transport inorganic anion exchanger activity,
symporter activity,
sodium:bicarbonate symporter activity,
protein binding
cytoplasm,
stereocilium,
basolateral plasma membrane,
integral to membrane,
apical plasma membrane
sodium ion transport
Ubiquitin carboxyl-terminal hydrolase 24 Ubiquitin C-Terminal Hydrolase ubiquitin thiolesterase activity,
cysteine-type peptidase activity
ubiquitin-dependent protein catabolic process
Grb10 Adapter molecule insulin receptor binding,
SH3/SH2 adaptor activity,
phosphotyrosine binding
plasma membrane,
cytoplasm,
cytosol
negative regulation of glucose import,
insulin-like growth factor receptor signaling pathway,
positive regulation of vascular endothelial growth factor receptor signaling pathway,
negative regulation of phosphorylation,
negative regulation of glycogen biosynthetic process,
negative regulation of insulin receptor signaling pathway,
negative regulation of Wnt receptor signaling pathway,
insulin receptor signaling pathway,
positive regulation of phosphorylation
Ubiquitin carboxyl-terminal hydrolase 5 Ubiquitin proteasome system protein ubiquitin thiolesterase activity,
cysteine-type endopeptidase activity,
cysteine-type peptidase activity,
zinc ion binding,
protein binding
lysosome positive regulation of proteasomal ubiquitin-dependent protein catabolic process,
ubiquitin-dependent protein catabolic process,
protein K48-linked deubiquitination
Carbon catabolite repressor CRES Metal ion binding protein nucleic acid binding,
zinc ion binding
intracellular
Monocarboxylate transporter 1 Proton-linked monocarboxylate transporter symporter activity,
mevalonate transmembrane transporter activity,
secondary active monocarboxylate transmembrane transporter activity,
protein binding
plasma membrane,
integral to membrane,
membrane fraction,
mitochondrion
organic anion transport
Probable ubiquitin carboxyl-terminal hydrolase FAF-X May function as a ubiquitin-protein or polyubiquitin hydrolase ubiquitin thiolesterase activity,
cysteine-type endopeptidase activity,
co-SMAD binding,
cysteine-type peptidase activity
cytoplasm mitosis,
ubiquitin-dependent protein catabolic process,
cell division,
BMP signaling pathway,
protein deubiquitination,
chromosome segregation,
female gamete generation,
transforming growth factor beta receptor signaling pathway
SH3-containing GRB2-like protein 1 Possible regulatory role in synaptic vesicle recycling lipid binding,
protein binding
early endosome membrane endocytosis,
central nervous system development,
signal transduction
SH3-domain GRB2-like Unclassified protein binding clathrin adaptor complex vesicle-mediated transport,
intracellular protein transport
Lrba Unclassified binding,
protein binding
plasma membrane,
integral to membrane,
Golgi apparatus,
endoplasmic reticulum,
cytoplasmic membrane-bounded vesicle,
trans-Golgi network,
lysosome
endosome transport,
signal transduction
Nrbp1 Unclassified ATP binding,
protein homodimerization activity,
protein kinase activity
perinuclear region of cytoplasm,
lamellipodium,
cell cortex,
membrane,
endomembrane system
protein amino acid phosphorylation,
ER to Golgi vesicle-mediated transport
Purb DNA binding protein mRNA binding,
single-stranded DNA binding,
double-stranded telomeric DNA binding,
SMAD binding,
transcription factor binding,
sequence-specific DNA binding transcription factor activity
DNA replication factor A complex regulation of myeloid cell differentiation,
apoptosis,
DNA unwinding involved in replication,
cell proliferation,
transcription,
negative regulation of transcription, DNA-dependent,
cell differentiation
RBM15B Unclassified RNA binding,
nucleotide binding,
protein binding
nucleoplasm regulation of alternative nuclear mRNA splicing, via spliceosome,
regulation of transcription,
interspecies interaction between organisms,
mRNA processing,
transcription,
RNA splicing
RBM16 Unclassified RNA binding,
nucleotide binding,
RNA polymerase core enzyme binding
spliceosomal complex,
nuclear matrix
mRNA processing,
RNA splicing
RBM25 RNA-binding motif mRNA binding,
nucleotide binding,
protein binding
cytoplasm,
nuclear speck
regulation of alternative nuclear mRNA splicing, via spliceosome,
apoptosis,
mRNA processing,
RNA splicing
RRBP1 Unclassified receptor activity ribosome,
integral to endoplasmic reticulum membrane
transmembrane transport,
protein transport,
translation
Serbp1 Unclassified mRNA 3`-UTR binding,
protein binding
perinuclear region of cytoplasm,
nucleus
regulation of mRNA stability
Sorbs1 Unclassified insulin receptor binding,
SH3/SH2 adaptor activity,
actin binding,
protein kinase binding
stress fiber,
cytosol,
membrane raft,
zonula adherens,
cell-cell adherens junction,
focal adhesion,
nucleus
stress fiber assembly,
focal adhesion assembly,
muscle contraction,
positive regulation of glycogen biosynthetic process,
positive regulation of lipid biosynthetic process,
glucose transport,
positive regulation of establishment of protein localization in plasma membrane,
insulin receptor signaling pathway,
positive regulation of glucose import
ErbB4 protein binding, protein heterodimerization activity ATP binding,
transmembrane receptor protein tyrosine kinase activity,
receptor signaling protein tyrosine kinase activity,
protein binding
basolateral plasma membrane,
integral to membrane,
nucleus
regulation of transcription,
transmembrane receptor protein tyrosine kinase signaling pathway,
cell proliferation,
transcription,
peptidyl-tyrosine phosphorylation
THRB protein binding, thyroid hormone receptor activity transcription corepressor activity,
steroid hormone receptor activity,
sequence-specific DNA binding,
thyroid hormone receptor activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity
nucleus regulation of transcription, DNA-dependent,
transcription, DNA-dependent
LILRB2 receptor activity receptor activity membrane fraction,
integral to plasma membrane
cellular defense response,
cell-cell signaling,
immune response,
cell surface receptor linked signaling pathway
Carbonic anhydrase-related protein 10 unclassified brain development
HNRBF-2 unclassified protein binding cytoplasm,
nucleus
regulation of transcription,
transcription
HSRBC protein kinase activity
MAK16-like protein RBM13 unclassified nucleolus
Monocarboxylate transporter 4 monocarboxylic acid transporter activity symporter activity,
secondary active monocarboxylate transmembrane transporter activity
plasma membrane,
integral to membrane,
membrane fraction,
integral to plasma membrane
organic anion transport
Monocarboxylate transporter 7 monocarboxylic acid transporter activity symporter activity,
monocarboxylic acid transmembrane transporter activity
membrane fraction,
integral to plasma membrane
Ankycorbin unclassified protein binding cytoskeleton,
cell cortex
RB1-inducible coiled-coil protein 1 unclassified protein binding ULK1-ATG13-FIP200 complex,
cytosol,
pre-autophagosomal structure,
nucleus
JNK cascade,
regulation of transcription,
heart development,
positive regulation of protein amino acid phosphorylation,
negative regulation of apoptosis,
transcription,
positive regulation of cell size,
cell cycle,
autophagic vacuole assembly,
liver development
Rb-associated protein unclassified protein homodimerization activity,
ubiquitin protein ligase binding,
zinc ion binding
synaptosome,
ubiquitin ligase complex,
chromosome,
nucleus
histone monoubiquitination,
histone H2B ubiquitination,
ubiquitin-dependent protein catabolic process
SH3-containing GRB2-like protein 2 identical protein binding identical protein binding,
lipid binding
plasma membrane,
cytosol
endocytosis,
central nervous system development,
post-Golgi vesicle-mediated transport,
signal transduction
RBM17 nucleotide binding RNA binding,
nucleic acid binding,
nucleotide binding,
protein binding
spliceosomal complex,
intracellular
mRNA processing,
RNA splicing, via transesterification reactions,
RNA splicing
VprBP protein unclassified protein binding cytoplasm,
nucleus
interspecies interaction between organisms
Gabrb3 Extracellular ligand gated channel chloride channel activity,
extracellular ligand-gated ion channel activity,
GABA-A receptor activity
cell junction,
chloride channel complex,
postsynaptic membrane
Grb7 Adapter molecule SH3/SH2 adaptor activity cytosol epidermal growth factor receptor signaling pathway
Rbm12ba RNA-binding protein RNA binding,
nucleotide binding
Hrb RNA binding protein DNA binding,
ARF GTPase activator activity,
RNA binding,
zinc ion binding,
protein binding
neuronal cell body,
cell projection,
Golgi apparatus,
nuclear pore,
cytoplasmic membrane-bounded vesicle,
nucleus
spermatid nucleus differentiation,
mRNA export from nucleus,
transport,
spermatogenesis,
intermediate filament organization,
regulation of ARF GTPase activity,
cell differentiation,
acrosome assembly,
multicellular organismal development
Rbpms2 RNA-binding protein nucleic acid binding,
nucleotide binding
Grb14 Adapter molecule SH3/SH2 adaptor activity Golgi membrane,
endosome membrane
RBM27 RNA binding protein RNA binding,
nucleotide binding,
zinc ion binding
cytoplasm,
nuclear speck
mRNA processing
SRBD1 RNA-binding protein RNA binding,
hydrolase activity, acting on ester bonds
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Ubiquitin carboxyl-terminal hydrolase 1 ubiquitin-specific protease activity,
ubiquitin thiolesterase activity,
cysteine-type endopeptidase activity,
protein binding
nucleoplasm ubiquitin-dependent protein catabolic process,
monoubiquitinated protein deubiquitination,
response to UV,
DNA repair,
regulation of DNA repair
Histone-binding protein RBBP7 protein binding ESC/E(Z) complex,
NuRD complex
regulation of transcription,
DNA replication,
cell proliferation,
chromatin modification,
transcription,
negative regulation of cell growth,
multicellular organismal development,
cellular heat acclimation
Ubiquitin carboxyl-terminal hydrolase 31 ubiquitin thiolesterase activity,
cysteine-type peptidase activity
ubiquitin-dependent protein catabolic process
LILRB4 antigen binding,
receptor activity
plasma membrane,
integral to membrane
Ubiquitin carboxyl-terminal hydrolase 28 ubiquitin-specific protease activity,
ubiquitin thiolesterase activity,
protein binding
nucleoplasm DNA damage checkpoint,
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis,
ubiquitin-dependent protein catabolic process,
cell proliferation,
DNA repair,
protein deubiquitination,
response to ionizing radiation
rbf-1 Rab GTPase binding,
zinc ion binding,
transporter activity
cell junction,
synaptic vesicle
intracellular protein transport,
exocytosis,
positive regulation of locomotion
rbc-2
Carboxypeptidase D structural constituent of cuticle,
metallocarboxypeptidase activity,
zinc ion binding,
protein binding
integral to membrane phagocytosis, engulfment,
imaginal disc-derived wing morphogenesis,
proteolysis
Hrb27C single-stranded DNA binding,
mRNA 3`-UTR binding,
mRNA 5`-UTR binding,
nucleotide binding,
protein binding
cytoplasm,
ribonucleoprotein complex,
protein complex,
nucleoplasm
negative regulation of oskar mRNA translation,
positive regulation of translation,
axon guidance,
pole plasm oskar mRNA localization,
border follicle cell migration,
regulation of nuclear mRNA splicing, via spliceosome
Probable RNA-binding protein orb2 RNA binding,
nucleotide binding,
protein binding
long-term memory,
male courtship behavior
M6PRBP1 protein binding lipid particle,
Golgi apparatus,
endosome membrane
vesicle-mediated transport
RBMS1 RNA binding,
single-stranded DNA binding,
double-stranded DNA binding,
protein binding
nucleus DNA replication,
RNA processing
CIRBP mRNA 3`-UTR binding,
SSU rRNA binding,
nucleotide binding,
translation repressor activity,
protein binding
stress granule,
nucleoplasm
stress granule assembly,
response to cold,
positive regulation of translation,
response to UV,
mRNA stabilization
SCARB2 receptor activity,
protein binding
lysosomal membrane,
membrane fraction,
integral to plasma membrane
cell adhesion
RBMS2 RNA binding,
nucleotide binding
nucleus RNA processing
RBPMS poly(A) RNA binding,
nucleotide binding,
transcription coactivator activity
cytoplasm,
nucleus
positive regulation of pathway-restricted SMAD protein phosphorylation,
transcription,
RNA processing,
positive regulation of SMAD protein nuclear translocation
RBM41 RNA binding,
nucleotide binding
RBM28 RNA binding,
nucleotide binding
spliceosomal complex,
nucleolus
mRNA processing,
RNA splicing

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