Phospho.ELM Result

a database of S/T/Y phosphorylation sites

PDK1 (3-phosphoinositide dependent protein kinase-1; serine/threonine kinase)

Seq-ID:

O15530 [Homo sapiens]

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Interaction Network(s):

External Source(s):

MINT Interaction(s):

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GO-Terms:

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Molecular Function	Cellular Component	Biological Process
3-phosphoinositide-dependent protein kinase activity, ATP binding, protein binding	plasma membrane, cytosol	intracellular signaling pathway, actin cytoskeleton organization, cellular response to insulin stimulus, positive regulation of establishment of protein localization in plasma membrane, negative regulation of protein kinase activity, peptidyl-threonine phosphorylation, activation of protein kinase B activity

Conservation:

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Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	241	SPESKQARANSFVGTAQYVSP	PDK-1	10455013	LTP	1.00	YWHAH 14-3-3; YWHAQ 14-3-3	S_TKc	0.25	1UU3	123.77%
S	241	SPESKQARANSFVGTAQYVSP	-	15302935	HTP	1.00	YWHAH 14-3-3; YWHAQ 14-3-3	S_TKc	0.25	1UU3	123.77%
S	241	SPESKQARANSFVGTAQYVSP	-	18669648	HTP	1.00	YWHAH 14-3-3; YWHAQ 14-3-3	S_TKc	0.25	1UU3	123.77%