Substrate: APBB1 (beta-amyloid binding, histone acetyltransferase binding)
Seq-ID: O00213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-74469   EGFR_HUMAN
MINT-74470   ERBB2_HUMAN
MINT-2856943   ATX1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone binding,
beta-amyloid binding,
transcription activator activity,
chromatin binding,
transcription factor binding,
proline-rich region binding		 plasma membrane,
cytoplasm,
lamellipodium,
synapse,
nucleus,
growth cone		 negative regulation of thymidylate synthase biosynthetic process,
transcription,
histone H4 acetylation,
apoptosis,
negative regulation of cell growth,
cell cycle arrest,
signal transduction,
negative regulation of S phase of mitotic cell cycle,
positive regulation of apoptosis,
axonogenesis,
response to DNA damage stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 175 DDEEEEEDLSSPPGLPEPLES MAPK1 14697653
LTP
1.00
 MOD_ProDKin_1
 - -
0.97
 --
S 287 TTQWEPPGRASPSQGSSPQEE MAPK1 14697653
LTP
0.01
 MOD_ProDKin_1
 - -
0.95
 --
S 347 GTLTFPAQSLSPEPLPQEEEK MAPK1 14697653
LTP
0.04
 MOD_ProDKin_1
 - -
0.82
 --
T 709 SLKPKRLGAHTP          MAPK1 14697653
LTP
0.00
 - -
0.31
 --

Substrate: APBB1 (beta-amyloid binding, histone acetyltransferase binding)
Seq-ID: P46933 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-49648   A4_HUMAN
MINT-49663   ABL1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
beta-amyloid binding,
transcription factor binding,
protein complex binding		 plasma membrane,
dendritic spine,
presynaptic membrane,
lamellipodium,
nucleus,
perinuclear region of cytoplasm,
protein complex,
growth cone,
postsynaptic membrane		 negative regulation of thymidylate synthase biosynthetic process,
transcription,
histone H4 acetylation,
apoptosis,
negative regulation of cell growth,
cell cycle arrest,
negative regulation of S phase of mitotic cell cycle,
positive regulation of apoptosis,
positive regulation of protein secretion,
positive regulation of DNA repair,
response to iron ion,
double-strand break repair,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 611 VLGECRVRFLSFLAVGRDVHT SGK_group 18304449
LTP
1.00
 - PTB
0.03
 3DXC 38.52%

Substrate: APBB1 (beta-amyloid binding, histone acetyltransferase binding)
Seq-ID: Q9QXJ1 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-7261896   P53_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
beta-amyloid binding,
transcription factor binding,
histone acetyltransferase binding		 plasma membrane,
lamellipodium,
nucleus,
growth cone		 negative regulation of thymidylate synthase biosynthetic process,
protein stabilization,
axon guidance,
transcription,
histone H4 acetylation,
apoptosis,
negative regulation of cell growth,
cell cycle arrest,
negative regulation of S phase of mitotic cell cycle,
positive regulation of apoptosis,
extracellular matrix organization,
neuron migration,
positive regulation of DNA repair,
visual learning,
double-strand break repair,
positive regulation of transcription from RNA polymerase II promoter,
actin filament-based movement
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 547 NELVQKFQVYYLGNVPVAKPV Abl 15031292
LTP
1.00
 - PTB
0.07
 3DXC 6.99%

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