Substrate: FYN (Cytoplasmic tyrosine kinase)
Seq-ID: P06241 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14847   WASP_HUMAN
MINT-15132   HNRPK_RAT
MINT-15408   KHDR1_HUMAN
MINT-15425   SHC1_HUMAN
MINT-16566   FYB_HUMAN
MINT-46000   CTNB1_MOUSE
MINT-50377   RASH_HUMAN
MINT-50652   MAP2_HUMAN
MINT-50666   CBL_HUMAN
MINT-61277   G3BP1_HUMAN
MINT-61574   CTNB1_RAT
MINT-2792095   PAK2_HUMAN
MINT-2792412   ADA15_HUMAN
MINT-2859062   ATX1_HUMAN
MINT-3381335   VGFR2_HUMAN
MINT-3381360   SRC_HUMAN
MINT-3381384   NCK1_HUMAN
MINT-4085360   TNR6_HUMAN
MINT-7214580   5HT6R_HUMAN
MINT-7245838   TRI39_HUMAN
MINT-7245886   ORC1_HUMAN
MINT-7245898   AKAP6_HUMAN
MINT-7245910   CENPA_HUMAN
MINT-7245922   LRBA_HUMAN
MINT-7245934   TRAIP_HUMAN
MINT-7245958   RPP38_HUMAN
MINT-7245970   HCN2_HUMAN
MINT-7246030   ASAP2_HUMAN
MINT-7246102   SYNJ2_HUMAN
MINT-7246150   RIMS1_HUMAN
MINT-7246210   DLGP4_HUMAN
MINT-7246222   LAP2B_HUMAN
MINT-7246246   TGON2_HUMAN
MINT-7246270   EPS15_HUMAN
MINT-7246306   CD2AP_HUMAN
MINT-7246318   MLL4_HUMAN
MINT-7246402   ARHGB_HUMAN
MINT-7246426   FLNC_HUMAN
MINT-7246450   SP1_HUMAN
MINT-7246474   RIMS2_HUMAN
MINT-7246522   ABL1_HUMAN
MINT-7246534   SNX12_HUMAN
MINT-7246558   M4K1_HUMAN
MINT-7246570   PRIC3_HUMAN
MINT-7246594   WNK2_HUMAN
MINT-7246630   RTN4_HUMAN
MINT-7246666   SF3B4_HUMAN
MINT-7246678   NFASC_HUMAN
MINT-7246714   GCF_HUMAN
MINT-7246726   PPR3D_HUMAN
MINT-7246750   BAZ2A_HUMAN
MINT-7246774   KI67_HUMAN
MINT-7246798   DDX41_HUMAN
MINT-7246810   DPOD1_HUMAN
MINT-7246834   FLNA_HUMAN
MINT-7246846   CDC27_HUMAN
MINT-7246870   SNX8_HUMAN
MINT-7246882   ABL2_HUMAN
MINT-7246918   ASAP1_HUMAN
MINT-7246930   MED14_HUMAN
MINT-7246954   WIPF1_HUMAN
MINT-7246978   E41L3_HUMAN
MINT-7247002   BCAR1_HUMAN
MINT-7247014   MYPT1_HUMAN
MINT-7247038   CAF1A_HUMAN
MINT-7247050   SHRM2_HUMAN
MINT-7247074   VP13A_HUMAN
MINT-7247086   CDKL5_HUMAN
MINT-7247098   ICAL_HUMAN
MINT-7247122   RRAS_HUMAN
MINT-7247134   NELFB_HUMAN
MINT-7247146   SPN90_HUMAN
MINT-7247158   CKAP5_HUMAN
MINT-7247170   FANCA_HUMAN
MINT-7247182   HDAC6_HUMAN
MINT-7247194   SNX3_HUMAN
MINT-7247206   BRPF3_HUMAN
MINT-7247230   XRCC1_HUMAN
MINT-7247242   DAB2_HUMAN
MINT-7247254   M4K5_HUMAN
MINT-7247290   STF1_HUMAN
MINT-7247302   DOCK1_HUMAN
MINT-7247350   BRCA2_HUMAN
MINT-7247374   RPGF1_HUMAN
MINT-7247422   DAG1_HUMAN
MINT-7247434   SUV92_HUMAN
MINT-7247446   FCG2B_HUMAN
MINT-7247458   FCG2C_HUMAN
MINT-7247482   CELR3_HUMAN
MINT-7247530   SOS1_HUMAN
MINT-7247554   MOS_HUMAN
MINT-7247566   SNX17_HUMAN
MINT-7306611   LCP2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
metal ion binding,
glycoprotein binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding		 plasma membrane,
endosome,
cytosol		 learning,
feeding behavior,
calcium ion transport,
interspecies interaction between organisms,
T cell receptor signaling pathway,
intracellular protein kinase cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 12 GCVQCKDKEATKLTEERDGSL - 15537652
LTP
0.10
 - -
0.52
 --
S 21 ATKLTEERDGSLNQSSGYRYG - 17192257
HTP
0.28
 - -
0.60
 --
S 21 ATKLTEERDGSLNQSSGYRYG - 18088087
HTP
0.28
 - -
0.60
 --
S 21 ATKLTEERDGSLNQSSGYRYG - 18669648
HTP
0.28
 - -
0.60
 --
Y 28 RDGSLNQSSGYRYGTDPTPQH Fyn 9425276
LTP
0.06
 - -
0.68
 --
Y 28 RDGSLNQSSGYRYGTDPTPQH PDGFR_beta 9425276
LTP
0.06
 - -
0.68
 --
Y 30 GSLNQSSGYRYGTDPTPQHYP Fyn 9425276
LTP
0.56
 - -
0.61
 --
Y 39 RYGTDPTPQHYPSFGVTSIPN Fyn 9425276
LTP
0.19
 - -
0.52
 --
Y 213 YKIRKLDNGGYYITTRAQFET - 18083107
HTP
0.70
 - SH2
0.20
 1G83 16.16%
Y 214 KIRKLDNGGYYITTRAQFETL - 16497976
HTP
1.00
 - SH2
0.21
 1G83 20.52%
Y 214 KIRKLDNGGYYITTRAQFETL - 18083107
HTP
1.00
 - SH2
0.21
 1G83 20.52%
Y 420 GLARLIEDNEYTARQGAKFPI Fyn 1985196
LTP
1.00
 - TyrKc
0.16
 2DQ7 44.98%
Y 420 GLARLIEDNEYTARQGAKFPI - 17192257
HTP
1.00
 - TyrKc
0.16
 2DQ7 44.98%
Y 420 GLARLIEDNEYTARQGAKFPI - 18088087
HTP
1.00
 - TyrKc
0.16
 2DQ7 44.98%
Y 420 GLARLIEDNEYTARQGAKFPI - 18083107
HTP
1.00
 - TyrKc
0.16
 2DQ7 44.98%
Y 440 IKWTAPEAALYGRFTIKSDVW - 18083107
HTP
0.79
 - TyrKc
0.07
 2DQ7 72.49%
Y 531 EDYFTATEPQYQPGENL     Csk 1985196
LTP
0.94
 MOD_TYR_CSK
 Fyn SH2;
Src SH2		 -
0.42
 --

Substrate: FYN (Cytoplasmic tyrosine kinase)
Seq-ID: P39688 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19527   BCAR1_MOUSE
MINT-19677   FAK1_MOUSE
MINT-19705   RAVR1_MOUSE
MINT-19779   KHDR1_MOUSE
MINT-19886   Q8C2G0_MOUSE
MINT-58736   SLAF1_MOUSE
MINT-58748   FYB_MOUSE
MINT-58749   SKAP2_MOUSE
MINT-7214442   P85A_MOUSE
MINT-7214472   PLCG2_MOUSE
MINT-7214763   CBL_MOUSE
MINT-7214822   CBL_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
tubulin binding		 plasma membrane,
cytosol		 myelination,
regulation of cell shape,
neuron migration,
protein amino acid autophosphorylation,
activated T cell proliferation,
peptidyl-tyrosine phosphorylation,
detection of mechanical stimulus involved in sensory perception of pain,
forebrain development,
response to ethanol
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 28 RDGSLNQSSGYRYGTDPTPQH - 8144681
LTP
0.05
 - -
0.67
 --
Y 420 GLARLIEDNEYTARQGAKFPI - 16339530
LTP
1.00
 - TyrKc
0.16
 2DQ7 44.98%
Y 531 EDYFTATEPQYQPGENL     - 16339530
LTP
0.89
 - -
0.42
 --

Substrate: FYN (Cytoplasmic tyrosine kinase)
Seq-ID: P39688-2 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
tubulin binding		 plasma membrane,
cytosol		 myelination,
regulation of cell shape,
neuron migration,
protein amino acid autophosphorylation,
activated T cell proliferation,
peptidyl-tyrosine phosphorylation,
detection of mechanical stimulus involved in sensory perception of pain,
forebrain development,
response to ethanol
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 21 AAKLTEERDGSLNQSSGYRYG - 19144319
HTP
0.25
 - -
0.57
 - low
Y 417 GLARLIEDNEYTARQGAKFPI - 19144319
HTP
1.00
 - TyrKc
0.16
 - low

Valid HTML 4.01 Transitional