a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	MAP3K7 (Mitogen-activated protein kinase kinase kinase 7)
Seq-ID:	ENSMUSP00000040307 [Mus musculus]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein serine/threonine kinase activity, MAP kinase kinase activity, ATP binding negative regulation of apoptosis, angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, MAPKKK cascade, I-kappaB phosphorylation, transforming growth factor beta receptor signaling pathway, positive regulation of JNK cascade, neural tube formation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	389	LPPTSEGKRMSADMSEIEARI	-	19144319	HTP	0.74		-	-	0.78	-	medium

Substrate:	MAP3K7 (Mitogen-activated protein kinase kinase kinase 7)
Seq-ID:	O43318 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-2842623   TAB1_HUMAN MINT-2842686   TAB2_HUMAN MINT-3391633   MP2K7_HUMAN MINT-4652778   IKKB_HUMAN MINT-4652797   NEMO_HUMAN MINT-6177574   MALT1_HUMAN MINT-6629291   JIP1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, ATP binding, MAP kinase kinase kinase activity, protein binding cytosol, endosome membrane positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JUN kinase activity, positive regulation of T cell cytokine production, activation of NF-kappaB-inducing kinase activity, I-kappaB phosphorylation, positive regulation of T cell activation, transforming growth factor beta receptor signaling pathway, T cell receptor signaling pathway, positive regulation of interleukin-2 production
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	184	CDFGTACDIQTHMTNNKGSAA	MAP3K7	10838074	LTP	1.00		-	STYKc	0.22	-	low
T	187	GTACDIQTHMTNNKGSAAWMA	MAP3K7	10838074	LTP	1.00		-	STYKc	0.26	-	low
S	192	IQTHMTNNKGSAAWMAPEVFE	MAP3K7	10838074	LTP	1.00		-	STYKc	0.31	-	low
S	389	LPPTSEGKRMSADMSEIEARI	-	18669648	HTP	0.79		-	-	0.80	-	low
S	439	ISGNGQPRRRSIQDLTVTGTE	-	18088087	HTP	0.68		-	-	0.79	-	low
S	439	ISGNGQPRRRSIQDLTVTGTE	-	18669648	HTP	0.68		-	-	0.79	-	low
S	454	TVTGTEPGQVSSRSSSPSVRM	-	18669648	HTP	0.25		-	-	0.79	-	low
S	455	VTGTEPGQVSSRSSSPSVRMI	-	18669648	HTP	0.02		-	-	0.79	-	low

Substrate:	MAP3K7 (Mitogen-activated protein kinase kinase kinase 7)
Seq-ID:	ENSMUSP00000040307 [Mus musculus]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, MAP kinase kinase activity, ATP binding, MAP kinase kinase kinase activity, protein binding negative regulation of apoptosis, angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, MAPKKK cascade, I-kappaB phosphorylation, transforming growth factor beta receptor signaling pathway, positive regulation of JNK cascade, neural tube formation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	439	ISGNGQPRRRSIQDLTVTGTE	-	19144319	HTP	0.75		-	-	0.78	-	medium

Substrate:	MAP3K7 (Mitogen-activated protein kinase kinase kinase 7)
Seq-ID:	ENSP00000358335 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	439	ISGNGQPRRRSIQDLTVTGTE	-	17081983	HTP	-		-	-	0.79	-	low

Substrate:	MAP3K7 (Mitogen-activated protein kinase kinase kinase 7)
Seq-ID:	Q62073 [Mus musculus]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, MAP kinase kinase activity, ATP binding, MAP kinase kinase kinase activity, protein binding negative regulation of apoptosis, angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, MAPKKK cascade, positive regulation of JUN kinase activity, I-kappaB phosphorylation, transforming growth factor beta receptor signaling pathway, positive regulation of JNK cascade, neural tube formation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	192	IQTHMTNNKGSAAWMAPEVFE	MAP3K7	10702308	LTP	1.00		-	STYKc	0.31	-	medium
S	412	TAGNGQPRRRSIQDLTVTGTE	-	17242355	HTP	0.66		-	-	0.84	-	medium
S	412	TAGNGQPRRRSIQDLTVTGTE	-	15647289	LTP	0.66		-	-	0.84	-	medium
S	412	TAGNGQPRRRSIQDLTVTGTE	-	17114649	HTP	0.66		-	-	0.84	-	medium