Substrate: APBB1 (beta-amyloid binding, histone acetyltransferase binding)
Seq-ID: O00213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-74469   EGFR_HUMAN
MINT-74470   ERBB2_HUMAN
MINT-2856943   ATX1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone binding,
beta-amyloid binding,
transcription activator activity,
chromatin binding,
transcription factor binding,
proline-rich region binding		 plasma membrane,
cytoplasm,
lamellipodium,
synapse,
nucleus,
growth cone		 negative regulation of thymidylate synthase biosynthetic process,
transcription,
histone H4 acetylation,
apoptosis,
negative regulation of cell growth,
cell cycle arrest,
signal transduction,
negative regulation of S phase of mitotic cell cycle,
positive regulation of apoptosis,
axonogenesis,
response to DNA damage stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 175 DDEEEEEDLSSPPGLPEPLES MAPK1 14697653
LTP
1.00
 MOD_ProDKin_1
 - -
0.97
 --
S 287 TTQWEPPGRASPSQGSSPQEE MAPK1 14697653
LTP
0.01
 MOD_ProDKin_1
 - -
0.95
 --
S 347 GTLTFPAQSLSPEPLPQEEEK MAPK1 14697653
LTP
0.04
 MOD_ProDKin_1
 - -
0.82
 --
T 709 SLKPKRLGAHTP          MAPK1 14697653
LTP
0.00
 - -
0.31
 --

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