Substrate: Menin.
Seq-ID: O00255 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
four-way junction DNA binding,
R-SMAD binding,
double-stranded DNA binding,
protein N-terminus binding,
Y-form DNA binding		 histone methyltransferase complex,
chromatin,
cytosol,
nuclear matrix,
soluble fraction,
cleavage furrow		 negative regulation of cyclin-dependent protein kinase activity,
response to UV,
negative regulation of transcription factor activity,
DNA repair,
negative regulation of cell proliferation,
MAPKKK cascade,
osteoblast development,
negative regulation of osteoblast differentiation,
response to gamma radiation,
positive regulation of transforming growth factor beta receptor signaling pathway,
negative regulation of JNK cascade,
negative regulation of transcription from RNA polymerase II promoter,
negative regulation of protein amino acid phosphorylation,
negative regulation of telomerase activity
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 399 EAGEERPGEQSQGTQSQGSAL - 17525332
HTP
0.40
 - Menin
0.85
 - medium
T 599 QVQMKKQKVSTPSDYTLSFLK - 18669648
HTP
0.47
 - Menin
0.59
 - medium

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