Substrate: PTEN (Lipid phosphatase)
Seq-ID: O08586 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-2832839   NHRF1_HUMAN
MINT-2832929   NHRF2_MOUSE
MINT-2832945   NHRF2_HUMAN
MINT-2833145   PGFRB_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
magnesium ion binding,
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity,
protein tyrosine phosphatase activity,
phosphatidylinositol-3-phosphatase activity,
protein serine/threonine phosphatase activity,
protein tyrosine/serine/threonine phosphatase activity,
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity,
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity,
PDZ domain binding		 nucleus inositol phosphate dephosphorylation,
cardiac muscle tissue development,
central nervous system development,
negative regulation of apoptosis,
regulation of cell cycle,
angiogenesis,
regulation of myeloid cell apoptosis,
negative regulation of epithelial cell proliferation,
regulation of neuron projection development,
apoptosis,
protein amino acid dephosphorylation,
prostate gland growth,
phosphoinositide dephosphorylation,
negative regulation of cell migration,
induction of apoptosis,
endothelial cell migration,
regulation of B cell apoptosis,
regulation of protein stability,
negative regulation of focal adhesion assembly,
negative regulation of protein kinase B signaling cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 370 SSSTSVTPDVSDNEPDHYRYS - 17242355
HTP
0.79
 - -
0.76
 - low
S 380 SDNEPDHYRYSDTTDSDPENE - 14522959
LTP
1.00
 - -
0.87
 - low
S 385 DHYRYSDTTDSDPENEPFDED - 17242355
HTP
1.00
 - -
0.86
 - low

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