Substrate: IKK-beta (Inhibitor of nuclear factor kappa B kinase beta subunit)
Seq-ID: O14920 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-47842   IKBA_HUMAN
MINT-47854   IKBB_HUMAN
MINT-47955   IKKA_HUMAN
MINT-48066   HS71L_HUMAN
MINT-48067   GRP78_HUMAN
MINT-48068   HSP7C_HUMAN
MINT-48070   GRP75_HUMAN
MINT-48071   IQGA1_HUMAN
MINT-48072   CDC37_HUMAN
MINT-48073   SYEP_HUMAN
MINT-48074   C1QBP_HUMAN
MINT-48075   SMRC1_HUMAN
MINT-48077   MYH10_HUMAN
MINT-48078   ACTG_HUMAN
MINT-48080   CLH1_HUMAN
MINT-48084   CALM_HUMAN
MINT-48085   TBB5_HUMAN
MINT-48086   TBB4_HUMAN
MINT-48087   K1967_HUMAN
MINT-48088   FLNA_HUMAN
MINT-48089   HNRPU_HUMAN
MINT-48090   PARP1_HUMAN
MINT-48091   HS90A_HUMAN
MINT-48093   HS90B_HUMAN
MINT-48174   NEMO_HUMAN
MINT-48434   M3K3_HUMAN
MINT-48728   NFKB2_HUMAN
MINT-48828   M3K14_HUMAN
MINT-50167   TF65_HUMAN
MINT-4652778   M3K7_HUMAN
MINT-4787797   MARK3_HUMAN
MINT-7295816   P53_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
transcription activator activity,
IkappaB kinase activity,
ATP binding		 membrane raft anti-apoptosis,
positive regulation of NF-kappaB transcription factor activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 177 LGYAKELDQGSLCTSFVGTLQ IKK_group 10779355
LTP
0.94
 - STYKc
0.08
 --
S 181 KELDQGSLCTSFVGTLQYLAP IKK_group 10195894
LTP
0.96
 - STYKc
0.08
 --
S 670 IACSKVRGPVSGSPDSMNASR IKK_group 10195894
LTP
0.19
 - -
0.55
 --
S 672 CSKVRGPVSGSPDSMNASRLS IKK_group 10195894
LTP
1.00
 - -
0.63
 --
S 672 CSKVRGPVSGSPDSMNASRLS - 18669648
HTP
1.00
 - -
0.63
 --
S 675 VRGPVSGSPDSMNASRLSQPG IKK_group 10195894
LTP
0.30
 - -
0.70
 --
S 682 SPDSMNASRLSQPGQLMSQPS IKK_group 10195894
LTP
0.19
 - -
0.73
 --
S 689 SRLSQPGQLMSQPSTASNSLP IKK_group 10195894
LTP
0.20
 - -
0.70
 --
S 692 SQPGQLMSQPSTASNSLPEPA IKK_group 10195894
LTP
0.79
 - -
0.75
 --
S 695 GQLMSQPSTASNSLPEPAKKS IKK_group 10195894
LTP
0.17
 - -
0.75
 --
S 697 LMSQPSTASNSLPEPAKKSEE IKK_group 10195894
LTP
0.31
 - -
0.74
 --
S 705 SNSLPEPAKKSEELVAEAHNL IKK_group 10195894
LTP
0.12
 - -
0.56
 3BRV 95.08%
S 733 IQDTVREQDQSFTALDWSWLQ IKK_group 10195894
LTP
1.00
 - -
0.41
 3BRV 40.98%
S 740 QDQSFTALDWSWLQTEEEEHS IKK_group 10195894
LTP
1.00
 - -
0.44
 3BRV 59.84%
S 750 SWLQTEEEEHSCLEQAS     IKK_group 10195894
LTP
0.19
 - -
0.52
 --

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