Substrate: Rho guanine nucleotide exchange factor 11 (protein binding)
Seq-ID: O15085 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7244302   ABL1_HUMAN
MINT-7246402   FYN_HUMAN
MINT-7250998   NCK1_HUMAN
MINT-7251574   P85A_HUMAN
MINT-7252498   PLCG1_HUMAN
MINT-7253674   GRB2_HUMAN
MINT-7254864   CRK_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
G-protein-coupled receptor binding,
GTPase activator activity,
signal transducer activity		 plasma membrane,
cytosol		 induction of apoptosis by extracellular signals,
regulation of cell growth,
actin cytoskeleton organization,
cytokinesis,
apoptosis,
establishment of cell polarity,
cellular component movement,
positive regulation of transcription, DNA-dependent,
Rho protein signal transduction,
striated muscle contraction,
regulation of Rho protein signal transduction,
G-protein coupled receptor protein signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 245 ESLMNRNSVLSDPGLDSPRTS - 18669648
HTP
1.00
 - -
0.74
 - medium
S 251 NSVLSDPGLDSPRTSPVIMAR - 17081983
HTP
1.00
 - -
0.64
 - medium
S 251 NSVLSDPGLDSPRTSPVIMAR - 18669648
HTP
1.00
 - -
0.64
 - medium
T 254 LSDPGLDSPRTSPVIMARVAQ - 18669648
HTP
1.00
 - -
0.65
 - medium
S 255 SDPGLDSPRTSPVIMARVAQH - 18669648
HTP
1.00
 - -
0.66
 - medium
S 663 SSSTSSLSTRSLENPTPPFTP - 17081983
HTP
1.00
 - -
0.82
 - medium
T 668 SLSTRSLENPTPPFTPKMGRR - 17081983
HTP
1.00
 - -
0.80
 - medium
T 668 SLSTRSLENPTPPFTPKMGRR - 18669648
HTP
1.00
 - -
0.80
 - medium
T 672 RSLENPTPPFTPKMGRRSIES - 18669648
HTP
1.00
 - -
0.81
 - medium
S 1155 VLLEDPEQEGSAEEEELGVLP - 18669648
HTP
0.73
 - -
0.87
 - medium
S 1295 LEHLPPRTRNSGIWESPELDR - 18669648
HTP
1.00
 - -
0.77
 - medium
S 1300 PRTRNSGIWESPELDRNLAED - 18669648
HTP
1.00
 - -
0.83
 - medium
S 1457 RELLKSLGGESSGGTTPVGSF - 18669648
HTP
0.08
 - -
0.81
 - medium
S 1458 ELLKSLGGESSGGTTPVGSFH - 18669648
HTP
1.00
 - -
0.82
 - medium
T 1461 KSLGGESSGGTTPVGSFHTEA - 18669648
HTP
1.00
 - -
0.83
 - medium
T 1462 SLGGESSGGTTPVGSFHTEAA - 18669648
HTP
1.00
 - -
0.83
 - medium
S 1466 ESSGGTTPVGSFHTEAARWTD - 18669648
HTP
1.00
 - -
0.81
 - medium
T 1475 GSFHTEAARWTDGSLSPPAKE - 18669648
HTP
1.00
 - -
0.81
 - medium
S 1480 EAARWTDGSLSPPAKEPLASD - 18669648
HTP
1.00
 - -
0.85
 - medium
S 1489 LSPPAKEPLASDSRNSHELGP - 18669648
HTP
1.00
 - -
0.91
 - medium
S 1491 PPAKEPLASDSRNSHELGPCP - 18669648
HTP
0.87
 - -
0.90
 - medium

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