Substrate: Hic-5 (Androgen receptor binding)
Seq-ID: O43294 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-61742   HIPK3_HUMAN
MINT-2863575   UBQL4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
I-SMAD binding,
androgen receptor binding,
transcription coactivator activity,
zinc ion binding,
Roundabout binding		 focal adhesion,
cytoplasm,
cytoskeleton,
nuclear matrix		 ubiquitin-dependent SMAD protein catabolic process,
transcription from RNA polymerase II promoter,
negative regulation of cell proliferation,
negative regulation of transforming growth factor beta receptor signaling pathway,
positive regulation of transcription, DNA-dependent,
Wnt receptor signaling pathway,
positive regulation of transforming growth factor beta receptor signaling pathway,
androgen receptor signaling pathway,
cell adhesion,
positive regulation of epithelial to mesenchymal transition
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 33 APKERPAEPLTPPPSYGHQPQ - 17081983
HTP
0.20
 - -
0.96
 - medium
Y 60 SGASGDKDHLYSTVCKPRSPK Fyn 10838081
LTP
0.08
 - -
0.75
 - medium
S 68 HLYSTVCKPRSPKPAAPAAPP - 17081983
HTP
0.26
 - -
0.73
 - medium
S 122 MSQFPSSKVASGEQKEDQSED - 17287340
HTP
0.65
 - -
0.88
 - medium
S 137 EDQSEDKKRPSLPSSPSPGLP - 17081983
HTP
0.00
 - -
0.94
 - medium
S 143 KKRPSLPSSPSPGLPKASATS - 17081983
HTP
0.16
 - -
0.87
 - medium
T 188 GPTQPPVVSSTNEGSPSPPEP - 17081983
HTP
0.02
 - -
0.94
 - medium

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