Substrate: DRIM (Unclassified)
Seq-ID: O75691 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-48187   NEMO_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein binding cytoplasm,
preribosome, small subunit precursor,
small-subunit processome,
nucleolus,
nucleoplasm,
90S preribosome		 negative regulation of cell proliferation,
endonucleolytic cleavage in 5`-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),
endonucleolytic cleavage to generate mature 5`-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 788 MTDEKSVGDESWEQTQEGDVG - 16565220
HTP
0.03
 - -
0.65
 - medium
T 1741 KSLSDNGQPGTPDPADSGGTS - 15302935
HTP
0.00
 - -
0.84
 - medium
T 1741 KSLSDNGQPGTPDPADSGGTS - 18669648
HTP
0.00
 - -
0.84
 - medium
T 2064 PPQSCLLLPPTPVRGGQKAVV - 16565220
HTP
1.00
 - -
0.33
 - medium
S 2637 SRIAKLEAAYSPRNPLKRTCI - 15302935
HTP
0.09
 - -
0.17
 - medium

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