Substrate: Caspase-8 precursor (Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death)
Seq-ID: O89110 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-4051926   ANDR_HUMAN
MINT-4051954   CASP8_HUMAN
MINT-4085319   TNR6_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cysteine-type endopeptidase activity mitochondrion,
Noc1p-Noc2p complex		 macrophage differentiation,
angiogenesis,
apoptosis,
heart development,
neural tube formation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 188 YERSSTERRMSLEGREELPPS - 17242355
HTP
0.10
 - -
0.63
 - medium

Valid HTML 4.01 Transitional