Substrate: LATS1 (serine/threonine kinase)
Seq-ID: O95835 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
magnesium ion binding,
protein serine/threonine kinase activity,
protein kinase binding,
ATP binding		 spindle pole,
microtubule organizing center		 negative regulation of cyclin-dependent protein kinase activity,
protein amino acid phosphorylation,
cell division,
cytoplasmic sequestering of protein,
regulation of actin filament polymerization,
positive regulation of peptidyl-serine phosphorylation,
hippo signaling cascade,
negative regulation of canonical Wnt receptor signaling pathway,
mitosis,
sister chromatid segregation,
G2/M transition of mitotic cell cycle,
hormone-mediated signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 244 VNPPPPPQVRSVTPPPPPRGQ - 15302935
HTP
0.57
 - -
0.98
 - medium
T 246 PPPPPQVRSVTPPPPPRGQTP - 18669648
HTP
0.24
 - -
0.98
 - medium
S 278 WEPNSQTKRYSGNMEYVISRI - 18220336
HTP
0.58
 - -
0.68
 - medium
S 278 WEPNSQTKRYSGNMEYVISRI - 18669648
HTP
0.58
 - -
0.68
 - medium
S 464 WQPNIPVRSNSFNNPLGNRAS - 15302935
HTP
1.00
 - -
0.77
 - medium
S 464 WQPNIPVRSNSFNNPLGNRAS - 18669648
HTP
1.00
 - -
0.77
 - medium
S 613 GDKEKKQITTSPITVRKNKKD - 15688006
LTP
1.00
 - -
0.81
 - medium
S 613 GDKEKKQITTSPITVRKNKKD CDK1 12372621
LTP
1.00
 - -
0.81
 - medium
S 633 DEERRESRIQSYSPQAFKFFM - 15688006
LTP
0.47
 - -
0.51
 - medium
S 674 LENEMMRVGLSQDAQDQMRKM - 17525332
HTP
0.65
 - -
0.54
 - medium
S 909 ARQHQRCLAHSLVGTPNYIAP - 15688006
LTP
1.00
 - S_TKc
0.25
 - medium
T 1079 KHPEHAFYEFTFRRFFDDNGY - 15688006
LTP
1.00
 - S_TK_X
0.28
 - medium
S 1111 YINSQGSEQQSDEDDQNTGSE - 15688006
LTP
0.00
 - -
0.90
 - medium

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