Substrate: Abl (Proto-oncogene tyrosine-protein kinase ABL1)
Seq-ID: P00519 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16419   WASF1_HUMAN
MINT-50717   CBL_HUMAN
MINT-59466   RIN1_HUMAN
MINT-74427   EGFR_HUMAN
MINT-74429   ERBB2_HUMAN
MINT-74430   ERBB3_HUMAN
MINT-74431   ERBB4_HUMAN
MINT-1955124   KPCD_HUMAN
MINT-1955144   B2CL1_HUMAN
MINT-2831131   EP300_HUMAN
MINT-2880967   MUC1_HUMAN
MINT-3390302   ABI2_HUMAN
MINT-4508216   CTNB1_HUMAN
MINT-6787710   PTN1_HUMAN
MINT-7034009   RAD51_HUMAN
MINT-7046591   SHB_HUMAN
MINT-7213827   PRDX1_HUMAN
MINT-7213847   BRCA1_HUMAN
MINT-7214943   M4K1_MOUSE
MINT-7218198   ADA15_HUMAN
MINT-7226098   ITB2_HUMAN
MINT-7226309   TLN2_HUMAN
MINT-7226674   VAV_HUMAN
MINT-7232904   HCK_HUMAN
MINT-7243294   TRI39_HUMAN
MINT-7243330   RPP38_HUMAN
MINT-7243390   HCN2_HUMAN
MINT-7243438   NFASC_HUMAN
MINT-7243462   CENPA_HUMAN
MINT-7243522   DYN2_HUMAN
MINT-7243582   DDX41_HUMAN
MINT-7243594   TGON2_HUMAN
MINT-7243606   SF3B4_HUMAN
MINT-7243630   AKAP6_HUMAN
MINT-7243654   BAZ2A_HUMAN
MINT-7243690   ORC1_HUMAN
MINT-7243726   MLL4_HUMAN
MINT-7243738   BRCA2_HUMAN
MINT-7243798   DPOD1_HUMAN
MINT-7243810   CELR3_HUMAN
MINT-7243846   SUV92_HUMAN
MINT-7243858   KI67_HUMAN
MINT-7243870   FLNC_HUMAN
MINT-7243882   CDKL5_HUMAN
MINT-7243894   CKAP5_HUMAN
MINT-7243906   PRIC3_HUMAN
MINT-7243954   SNX8_HUMAN
MINT-7243966   EPS15_HUMAN
MINT-7243978   VP13A_HUMAN
MINT-7243990   SNX12_HUMAN
MINT-7244002   SNX17_HUMAN
MINT-7244026   CDC27_HUMAN
MINT-7244086   SPN90_HUMAN
MINT-7244098   LRBA_HUMAN
MINT-7244134   CTGE5_HUMAN
MINT-7244146   ICAL_HUMAN
MINT-7244182   FETUA_HUMAN
MINT-7244194   WNK2_HUMAN
MINT-7244206   RPGF1_HUMAN
MINT-7244230   CD2AP_HUMAN
MINT-7244302   ARHGB_HUMAN
MINT-7244314   SP1_HUMAN
MINT-7244350   OSBL5_HUMAN
MINT-7244362   RTN4_HUMAN
MINT-7244374   MED14_HUMAN
MINT-7244446   SYNJ2_HUMAN
MINT-7244482   ACAP1_HUMAN
MINT-7244494   NELFB_HUMAN
MINT-7244542   LAP2B_HUMAN
MINT-7244554   P2RX7_HUMAN
MINT-7244566   FYB_HUMAN
MINT-7244602   E41L3_HUMAN
MINT-7244614   SNX3_HUMAN
MINT-7244626   GT2D1_HUMAN
MINT-7244638   DYN1_HUMAN
MINT-7244650   ASAP1_HUMAN
MINT-7244662   G3BP2_HUMAN
MINT-7244674   DNLI3_HUMAN
MINT-7244698   DLGP4_HUMAN
MINT-7244746   BRPF3_HUMAN
MINT-7244806   M4K1_HUMAN
MINT-7244830   CUL7_HUMAN
MINT-7244866   FLNA_HUMAN
MINT-7244878   RIMS1_HUMAN
MINT-7245034   SRC_HUMAN
MINT-7246522   FYN_HUMAN
MINT-7249642   NCK1_HUMAN
MINT-7251418   P85A_HUMAN
MINT-7252738   PLCG1_HUMAN
MINT-7253218   GRB2_HUMAN
MINT-7254106   CRK_HUMAN
MINT-7297574   MAVS_HUMAN
MINT-7301011   TOP1_HUMAN
MINT-7309761   P73_HUMAN
MINT-7385614   3BP1_MOUSE
MINT-7385781   ABI1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
magnesium ion binding,
manganese ion binding,
DNA binding,
protein C-terminus binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
proline-rich region binding		 cytosol,
nuclear membrane,
cytoskeleton,
nucleolus,
perinuclear region of cytoplasm		 regulation of transcription involved in S phase of mitotic cell cycle,
mismatch repair,
actin cytoskeleton organization,
signal transduction,
cell adhesion,
peptidyl-tyrosine phosphorylation,
positive regulation of oxidoreductase activity,
DNA damage response, signal transduction resulting in induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 185 RINTASDGKLYVSSESRFNTL - 12522270
HTP
0.96
 - SH2
0.32
 1OPK 18.78%
Y 185 RINTASDGKLYVSSESRFNTL - 18083107
HTP
0.96
 - SH2
0.32
 1OPK 18.78%
Y 226 PAPKRNKPTVYGVSPNYDKWE - 10964922
LTP
1.00
 - -
0.43
 1OPK 24.02%
Y 226 PAPKRNKPTVYGVSPNYDKWE - 11847100
LTP
1.00
 - -
0.43
 1OPK 24.02%
Y 226 PAPKRNKPTVYGVSPNYDKWE - 12522270
HTP
1.00
 - -
0.43
 1OPK 24.02%
Y 264 GEVYEGVWKKYSLTVAVKTLK - 12522270
HTP
1.00
 - TyrKc
0.11
 2HZI 55.02%
Y 393 GLSRLMTGDTYTAHAGAKFPI Abl 11781820
LTP
1.00
 - TyrKc
0.13
 2HZI 29.69%
Y 393 GLSRLMTGDTYTAHAGAKFPI Abl 10964922
LTP
1.00
 - TyrKc
0.13
 2HZI 29.69%
Y 393 GLSRLMTGDTYTAHAGAKFPI - 12522270
HTP
1.00
 - TyrKc
0.13
 2HZI 29.69%
T 394 LSRLMTGDTYTAHAGAKFPIK - 12522270
HTP
1.00
 - TyrKc
0.13
 2HZI 61.64%
S 446 GMSPYPGIDLSQVYELLEKDY ATM 9168116
LTP
0.87
 MOD_PIKK_1
 - TyrKc
0.20
 2HZI 68.03%
S 569 SDPLDHEPAVSPLLPRKERGP - 17081983
HTP
0.75
 - -
0.91
 --
S 569 SDPLDHEPAVSPLLPRKERGP - 17192257
HTP
0.75
 - -
0.91
 --
S 569 SDPLDHEPAVSPLLPRKERGP - 18220336
HTP
0.75
 - -
0.91
 --
S 569 SDPLDHEPAVSPLLPRKERGP - 18669648
HTP
0.75
 - -
0.91
 --
T 735 GAKDTEWRSVTLPRDLQSTGR TTK 18794806
LTP
1.00
 - -
0.74
 --
T 844 EEAGKGSALGTPAAAEPVTPT - 18669648
HTP
0.10
 - -
0.91
 --
T 852 LGTPAAAEPVTPTSKAGSGAP - 18669648
HTP
0.10
 - -
0.92
 --
T 854 TPAAAEPVTPTSKAGSGAPGG - 18669648
HTP
0.64
 - -
0.93
 --
S 917 AGKAGGKPSQSPSQEAAGEAV - 18669648
HTP
0.40
 - -
0.91
 --
S 949 DAVNSDAAKPSQPGEGLKKPV - 17081983
HTP
0.50
 - -
0.84
 --

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