Substrate: Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )
Seq-ID: P03372 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-13786   BRCA1_HUMAN
MINT-50646   STA5A_HUMAN
MINT-50709   M3K1_HUMAN
MINT-5222241   NCOA1_HUMAN
MINT-6169667   EGFR_HUMAN
MINT-6614126   SMCA4_HUMAN
MINT-6614301   CHD3_HUMAN
MINT-6614361   MTA1_HUMAN
MINT-6614421   MTA2_HUMAN
MINT-6761899   PTN1_HUMAN
MINT-6761906   PTN6_HUMAN
MINT-7013584   PA1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
beta-catenin binding,
nitric-oxide synthase regulator activity,
estrogen response element binding,
steroid binding,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
estrogen receptor activity		 chromatin remodeling complex response to estradiol stimulus,
transcription, DNA-dependent,
regulation of transcription, DNA-dependent,
positive regulation of retinoic acid receptor signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 46 ERPLGEVYLDSSKPAVYNYPE - 20043841
LTP
0.14
 - Oest_recep
0.37
 --
S 47 RPLGEVYLDSSKPAVYNYPEG - 20043841
LTP
0.91
 - Oest_recep
0.38
 --
Y 52 VYLDSSKPAVYNYPEGAAYEF - 20101225
LTP
0.00
 SHC1 SH2 Oest_recep
0.31
 --
S 102 NGLGGFPPLNSVSPSPLMLLH GSK-3_beta 16076840
LTP
0.85
 MOD_GSK3_1
 - Oest_recep
0.46
 --
S 102 NGLGGFPPLNSVSPSPLMLLH - 18984578
LTP
0.85
 MOD_GSK3_1
 - Oest_recep
0.46
 --
S 104 LGGFPPLNSVSPSPLMLLHPP - 8308015
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP CDK_group 10949034
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP GSK-3_beta 10949034
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP GSK-3_beta 16076840
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP CDK_group 10428798
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP - 18984578
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP - 16741565
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 104 LGGFPPLNSVSPSPLMLLHPP - 20043841
LTP
0.61
 MOD_GSK3_1
 - Oest_recep
0.48
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ - 8308015
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ - 10949034
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ GSK-3_beta 16076840
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ CDK_group 10428798
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ - 18984578
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ - 16741565
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 106 GFPPLNSVSPSPLMLLHPPPQ - 20043841
LTP
0.96
 MOD_GSK3_1
 - Oest_recep
0.52
 --
S 118 LMLLHPPPQLSPFLQPHGQQV RSK_group 7838153
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV MAPK_group 12093745
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV - 9528769
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV CDK7 10949034
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV GSK-3_beta 16076840
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV - 15528270
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV CDK7 15461668
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV MAPK1 15059947
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV MAPK_group 12118371
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV CDK7 12118371
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV MAPK3 7491495
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV - 18984578
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV - 16741565
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 118 LMLLHPPPQLSPFLQPHGQQV - 20043841
LTP
1.00
 MOD_ProDKin_1
 - Oest_recep
0.50
 --
S 154 AGPPAFYRPNSDNRRQGGRER - 18984578
LTP
0.29
 - Oest_recep
0.72
 --
S 167 RRQGGRERLASTNDKGSMAME RSK_group 7838153
LTP
0.28
 MOD_PKB_1
 - Oest_recep
0.75
 --
S 167 RRQGGRERLASTNDKGSMAME - 9528769
LTP
0.28
 MOD_PKB_1
 - Oest_recep
0.75
 --
S 167 RRQGGRERLASTNDKGSMAME RSK_group 11432835
LTP
0.28
 MOD_PKB_1
 - Oest_recep
0.75
 --
S 167 RRQGGRERLASTNDKGSMAME PKB_beta 11139588
LTP
0.28
 MOD_PKB_1
 - Oest_recep
0.75
 --
S 167 RRQGGRERLASTNDKGSMAME - 18984578
LTP
0.28
 MOD_PKB_1
 - Oest_recep
0.75
 --
S 167 RRQGGRERLASTNDKGSMAME - 16741565
LTP
0.28
 MOD_PKB_1
 - Oest_recep
0.75
 --
S 212 CEGCKAFFKRSIQGHNDYMCP - 18984578
LTP
1.00
 - ZnF_C4
0.19
 1HCQ 1.64%
Y 219 FKRSIQGHNDYMCPATNQCTI - 20101225
LTP
1.00
 - ZnF_C4
0.33
 1HCQ 22.71%
S 236 QCTIDKNRRKSCQACRLRKCY PKA_group 9891036
LTP
1.00
 MOD_PKA_1
 - ZnF_C4
0.22
 1HCQ 73.77%
S 236 QCTIDKNRRKSCQACRLRKCY - 18984578
LTP
1.00
 MOD_PKA_1
 - ZnF_C4
0.22
 1HCQ 73.77%
S 236 QCTIDKNRRKSCQACRLRKCY - 16741565
LTP
1.00
 MOD_PKA_1
 - ZnF_C4
0.22
 1HCQ 73.77%
S 282 DDGEGRGEVGSAGDMRAANLW - 20043841
LTP
0.19
 - -
0.51
 --
S 294 GDMRAANLWPSPLMIKRSKKN - 18984578
LTP
0.16
 - -
0.34
 --
S 294 GDMRAANLWPSPLMIKRSKKN - 20043841
LTP
0.16
 - -
0.34
 --
S 305 PLMIKRSKKNSLALSLTADQM PAK1 12374744
LTP
0.93
 - -
0.31
 2QA8 64.75%
S 305 PLMIKRSKKNSLALSLTADQM - 15193262
LTP
0.93
 - -
0.31
 2QA8 64.75%
S 305 PLMIKRSKKNSLALSLTADQM - 16741565
LTP
0.93
 - -
0.31
 2QA8 64.75%
S 305 PLMIKRSKKNSLALSLTADQM - 16452229
LTP
0.93
 - -
0.31
 2QA8 64.75%
S 305 PLMIKRSKKNSLALSLTADQM - 17627277
LTP
0.93
 - -
0.31
 2QA8 64.75%
T 311 SKKNSLALSLTADQMVSALLD MAPK_group 12138194
LTP
0.27
 - -
0.28
 2IOG 52.05%
T 311 SKKNSLALSLTADQMVSALLD MAPK14 12138194
LTP
0.27
 - -
0.28
 2IOG 52.05%
T 311 SKKNSLALSLTADQMVSALLD - 16741565
LTP
0.27
 - -
0.28
 2IOG 52.05%
Y 537 SMKCKNVVPLYDLLLEMLDAH Lck 7539106
LTP
0.96
 Src SH2 Hormone_recep
0.06
 2IOG 27.07%
Y 537 SMKCKNVVPLYDLLLEMLDAH SRC 7539106
LTP
0.96
 Src SH2 Hormone_recep
0.06
 2IOG 27.07%
Y 537 SMKCKNVVPLYDLLLEMLDAH - 16741565
LTP
0.96
 Src SH2 Hormone_recep
0.06
 2IOG 27.07%
S 554 LDAHRLHAPTSRGGASVEETD - 18984578
LTP
0.10
 - -
0.61
 --
S 559 LHAPTSRGGASVEETDQSHLA - 18984578
LTP
0.57
 - -
0.67
 --
S 559 LHAPTSRGGASVEETDQSHLA - 20043841
LTP
0.57
 - -
0.67
 --

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