Substrate: Beta-2 adrenergic receptor (Protein G coupled receptor)
Seq-ID: P04274 [Mesocricetus auratus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
norepinephrine binding,
beta2-adrenergic receptor activity		 plasma membrane,
receptor complex,
integral to membrane		 positive regulation of MAPKKK cascade,
receptor-mediated endocytosis,
activation of adenylate cyclase activity,
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 132 ETLCVIAVDRYIAITSPFKYQ INSR 8557631
LTP
1.00
 - 7tm_1
0.01
 - medium
Y 132 ETLCVIAVDRYIAITSPFKYQ IGF1R 8910597
LTP
1.00
 - 7tm_1
0.01
 - medium
Y 141 RYIAITSPFKYQSLLTKNKAR - 8521811
LTP
1.00
 - 7tm_1
0.02
 - medium
Y 141 RYIAITSPFKYQSLLTKNKAR INSR 8557631
LTP
1.00
 - 7tm_1
0.02
 - medium
Y 350 LCLRRSSSKAYGNGYSSNSNG - 8521811
LTP
0.10
 GRB2 SH2 -
0.30
 - medium
Y 350 LCLRRSSSKAYGNGYSSNSNG INSR 8557631
LTP
0.10
 GRB2 SH2 -
0.30
 - medium
Y 354 RSSSKAYGNGYSSNSNGKTDY - 8521811
LTP
0.08
 - -
0.42
 - medium
Y 354 RSSSKAYGNGYSSNSNGKTDY INSR 8557631
LTP
0.08
 - -
0.42
 - medium
Y 364 YSSNSNGKTDYMGEASGCQLG - 8521811
LTP
0.15
 - -
0.39
 - medium
Y 364 YSSNSNGKTDYMGEASGCQLG INSR 8557631
LTP
0.15
 - -
0.39
 - medium
S 369 NGKTDYMGEASGCQLGQEKES GRK_group 8132675
LTP
0.16
 - -
0.42
 - medium
S 379 SGCQLGQEKESERLCEDPPGT GRK_group 8132675
LTP
0.72
 - -
0.46
 - medium
T 389 SERLCEDPPGTESFVNCQGTV GRK_group 8132675
LTP
0.45
 - -
0.37
 - medium
S 391 RLCEDPPGTESFVNCQGTVPS GRK_group 8132675
LTP
0.23
 - -
0.35
 - medium
S 406 QGTVPSLSLDSQGRNCSTNDS GRK_group 8132675
LTP
0.44
 - -
0.43
 - medium
S 412 LSLDSQGRNCSTNDSPL     GRK_group 8132675
LTP
0.44
 - -
0.48
 - medium
T 413 SLDSQGRNCSTNDSPL      GRK_group 8132675
LTP
0.93
 - -
0.49
 - medium
S 416 SQGRNCSTNDSPL         GRK_group 8132675
LTP
0.00
 - -
0.44
 - medium

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