Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Beta-2 adrenergic receptor (Protein G coupled receptor)

Seq-ID:

P07550 [Homo sapiens]

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Interaction Network(s):

External Source(s):

MINT Interaction(s):

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GO-Terms:

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Molecular Function	Cellular Component	Biological Process
potassium channel regulator activity, protein homodimerization activity, norepinephrine binding, beta2-adrenergic receptor activity	receptor complex, endosome, integral to plasma membrane, lysosome	positive regulation of MAPKKK cascade, receptor-mediated endocytosis, activation of transmembrane receptor protein tyrosine kinase activity, endosome to lysosome transport, desensitization of G-protein coupled receptor protein signaling pathway by arrestin

Conservation:

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Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	132	ETLCVIAVDRYFAITSPFKYQ	IGF1R	8910597	LTP	1.00		-	7tm_1	0.01	2R4R	24.02%
Y	141	RYFAITSPFKYQSLLTKNKAR	IGF1R	8910597	LTP	1.00		-	7tm_1	0.01	2R4R	13.10%
S	246	SEGRFHVQNLSQVEQDGRTGH	-	17525332	HTP	0.18		-	7tm_1	0.31	-	-
S	262	GRTGHGLRRSSKFCLKEHKAL	-	8083204	LTP	1.00	MOD_PKA_1	-	7tm_1	0.20	-	-
S	262	GRTGHGLRRSSKFCLKEHKAL	PKA_group	11146000	LTP	1.00	MOD_PKA_1	-	7tm_1	0.20	-	-
Y	326	YVNSGFNPLIYCRSPDFRIAF	-	7559596	LTP	0.99		-	TRANS	0.06	2R4R	8.30%
S	345	AFQELLCLRRSSLKAYGNGYS	-	8083204	LTP	0.14	MOD_PKA_1	-	-	0.08	2R4R	83.61%
S	345	AFQELLCLRRSSLKAYGNGYS	PKA_group	11146000	LTP	0.14	MOD_PKA_1	-	-	0.08	2R4R	83.61%
S	346	FQELLCLRRSSLKAYGNGYSS	-	8083204	LTP	0.18	MOD_PKA_1	-	-	0.10	2R4R	28.69%
S	346	FQELLCLRRSSLKAYGNGYSS	PKA_group	11146000	LTP	0.18	MOD_PKA_1	-	-	0.10	2R4R	28.69%
S	346	FQELLCLRRSSLKAYGNGYSS	PKB_group	11809767	LTP	0.18	MOD_PKA_1	-	-	0.10	2R4R	28.69%
S	355	SSLKAYGNGYSSNGNTGEQSG	GRK_group	14722251	LTP	0.13		-	-	0.42	-	-
S	356	SLKAYGNGYSSNGNTGEQSGY	GRK_group	14722251	LTP	0.04		-	-	0.42	-	-
T	384	NKLLCEDLPGTEDFVGHQGTV	GRK-2	8662852	LTP	0.67		-	-	0.31	-	-
T	384	NKLLCEDLPGTEDFVGHQGTV	GRK-5	8662852	LTP	0.67		-	-	0.31	-	-
T	393	GTEDFVGHQGTVPSDNIDSQG	GRK-5	8662852	LTP	0.19		-	-	0.50	-	-
S	396	DFVGHQGTVPSDNIDSQGRNC	GRK-2	8662852	LTP	0.08		-	-	0.50	-	-
S	396	DFVGHQGTVPSDNIDSQGRNC	GRK-5	8662852	LTP	0.08		-	-	0.50	-	-
S	401	QGTVPSDNIDSQGRNCSTNDS	GRK-2	8662852	LTP	0.24		-	-	0.53	-	-
S	401	QGTVPSDNIDSQGRNCSTNDS	GRK-5	8662852	LTP	0.24		-	-	0.53	-	-
S	407	DNIDSQGRNCSTNDSLL	GRK-2	8662852	LTP	0.21		-	-	0.44	-	-
S	407	DNIDSQGRNCSTNDSLL	GRK-5	8662852	LTP	0.21		-	-	0.44	-	-
S	411	SQGRNCSTNDSLL	GRK-5	8662852	LTP	0.00		-	-	0.34	-	-