Substrate: CD3 epsilon (T cell surface glycoprotein)
Seq-ID: P07766 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-7213943   NCK2_HUMAN
MINT-7214058   EPS8_HUMAN
MINT-7214076   ES8L2_HUMAN
MINT-7214253   ES8L1_HUMAN
MINT-7234008   NCK1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
T cell receptor binding,
protein heterodimerization activity,
protein kinase binding,
receptor signaling complex scaffold activity,
transmembrane receptor activity,
receptor signaling protein activity		 external side of plasma membrane,
integral to plasma membrane		 signal complex assembly,
G-protein coupled receptor protein signaling pathway
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 188 ERPPPVPNPDYEPIRKGQRDL - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.67
 - medium
Y 188 ERPPPVPNPDYEPIRKGQRDL - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.67
 - medium
Y 188 ERPPPVPNPDYEPIRKGQRDL - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.67
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 12522270
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15144186
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15592455
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 16094384
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 15659558
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium
Y 199 EPIRKGQRDLYSGLNQRRI   - 18083107
HTP
1.00
 Fyn SH2;
Lck SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2		 ITAM
0.40
 - medium

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