Substrate: PDHE1-A type I (pyruvate dehydrogenase E1 component (from PhosphoBase))
Seq-ID: P08559 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
pyruvate dehydrogenase (acetyl-transferring) activity,
protein binding		 mitochondrial matrix oxidation reduction,
regulation of acetyl-CoA biosynthetic process from pyruvate,
glycolysis
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 231 ICENNRYGMGTSVERAAASTD - 18669648
HTP
0.98
 - E1_dh
0.24
 2OZL 36.30%
S 232 CENNRYGMGTSVERAAASTDY - 7273851
LTP
0.97
 - E1_dh
0.27
 2OZL 14.75%
S 232 CENNRYGMGTSVERAAASTDY - 15302935
HTP
0.97
 - E1_dh
0.27
 2OZL 14.75%
S 232 CENNRYGMGTSVERAAASTDY - 17081983
HTP
0.97
 - E1_dh
0.27
 2OZL 14.75%
S 232 CENNRYGMGTSVERAAASTDY - 18088087
HTP
0.97
 - E1_dh
0.27
 2OZL 14.75%
S 232 CENNRYGMGTSVERAAASTDY - 18220336
HTP
0.97
 - E1_dh
0.27
 2OZL 14.75%
Y 289 PILMELQTYRYHGHSMSDPGV - 16497976
HTP
1.00
 - E1_dh
0.33
 2OZL 5.24%
Y 289 PILMELQTYRYHGHSMSDPGV - 18083107
HTP
1.00
 - E1_dh
0.33
 2OZL 5.24%
S 293 ELQTYRYHGHSMSDPGVSYRT - 7273851
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT - 15302935
HTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK1 11486000
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK2 11486000
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK3 11486000
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK4 11486000
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK1 16436377
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK2 16436377
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK3 16436377
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT PDHK4 16436377
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT - 17081983
HTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT - 17474719
LTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 293 ELQTYRYHGHSMSDPGVSYRT - 18220336
HTP
1.00
 - E1_dh
0.37
 2OZL 13.11%
S 295 QTYRYHGHSMSDPGVSYRTRE - 17081983
HTP
1.00
 - E1_dh
0.43
 2OZL 76.23%
S 295 QTYRYHGHSMSDPGVSYRTRE - 18220336
HTP
1.00
 - E1_dh
0.43
 2OZL 76.23%
S 300 HGHSMSDPGVSYRTREEIQEV - 7273851
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV - 15302935
HTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK1 11486000
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK2 11486000
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK3 11486000
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK4 11486000
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK1 16436377
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK2 16436377
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK3 16436377
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV PDHK4 16436377
LTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV - 17081983
HTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
S 300 HGHSMSDPGVSYRTREEIQEV - 18220336
HTP
1.00
 - E1_dh
0.50
 2OZL 90.16%
Y 301 GHSMSDPGVSYRTREEIQEVR - 16497976
HTP
1.00
 - E1_dh
0.52
 2OZL 20.96%
Y 301 GHSMSDPGVSYRTREEIQEVR - 18083107
HTP
1.00
 - E1_dh
0.52
 2OZL 20.96%
Y 301 GHSMSDPGVSYRTREEIQEVR - 18220336
HTP
1.00
 - E1_dh
0.52
 2OZL 20.96%

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