Substrate: PDGF-R beta (Beta platelet-derived growth factor receptor)
Seq-ID: P09619 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-2832596   NHRF2_HUMAN
MINT-2832984   PTEN_HUMAN
MINT-2833042   NHRF1_HUMAN
MINT-6762380   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
vascular endothelial growth factor receptor activity,
platelet-derived growth factor binding,
platelet activating factor receptor activity,
platelet-derived growth factor receptor binding,
ATP binding,
platelet-derived growth factor beta-receptor activity		 integral to plasma membrane positive regulation of cell proliferation,
positive regulation of cell migration,
protein amino acid autophosphorylation,
peptidyl-tyrosine phosphorylation,
cell chemotaxis
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 562 LIMLWQKKPRYEIRWKVIESV PDGFR_beta 10821867
LTP
1.00
 - -
0.06
 - medium
Y 579 IESVSSDGHEYIYVDPMQLPY PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
SLA SH2;
Src SH2;
STAT5 SH2;
YES1 SH2		 -
0.15
 - medium
Y 581 SVSSDGHEYIYVDPMQLPYDS PDGFR_beta 8617789
LTP
1.00
 Fyn SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2;
RASA_group SH2;
SLA SH2;
Src SH2;
STAT5 SH2;
YES1 SH2		 -
0.16
 - medium
Y 716 DKRRPPSAELYSNALPVGLPL PDGFR_beta 8940081
LTP
1.00
 GRB2 SH2;
GRB7 SH2		 TyrKc
0.46
 - medium
Y 716 DKRRPPSAELYSNALPVGLPL PDGFR_beta 7935391
LTP
1.00
 GRB2 SH2;
GRB7 SH2		 TyrKc
0.46
 - medium
Y 740 VSLTGESDGGYMDMSKDESVD PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2		 TyrKc
0.45
 - medium
Y 751 MDMSKDESVDYVPMLDMKGDV PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
Src SH2		 TyrKc
0.29
 - medium
Y 751 MDMSKDESVDYVPMLDMKGDV PDGFR_group 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
Src SH2		 TyrKc
0.29
 - medium
Y 763 PMLDMKGDVKYADIESSNYMA - 10821867
LTP
0.28
 PTPN11 SH2 TyrKc
0.21
 - medium
Y 763 PMLDMKGDVKYADIESSNYMA PDGFR_beta N.N.
LTP
0.28
 PTPN11 SH2 TyrKc
0.21
 - medium
Y 763 PMLDMKGDVKYADIESSNYMA PDGFR_beta 10391677
LTP
0.28
 PTPN11 SH2 TyrKc
0.21
 - medium
Y 771 VKYADIESSNYMAPYDNYVPS PDGFR_beta 8195171
LTP
1.00
 CRK SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2		 TyrKc
0.25
 - medium
Y 775 DIESSNYMAPYDNYVPSAPER PDGFR_beta 8940081
LTP
1.00
 GRB2 SH2;
GRB7 SH2;
STAT5 SH2		 TyrKc
0.34
 - medium
Y 778 SSNYMAPYDNYVPSAPERTCR PDGFR_beta 10821867
LTP
0.02
 - TyrKc
0.33
 - medium
Y 778 SSNYMAPYDNYVPSAPERTCR - 9394017
LTP
0.02
 - TyrKc
0.33
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_beta 10821867
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_group 10821867
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_beta 2550144
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_group 2550144
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 1009 RSPLDTSSVLYTAVQPNEGDN PDGFR_beta 8195171
LTP
0.02
 NCK SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2		 -
0.61
 - medium
Y 1021 AVQPNEGDNDYIIPLPDPKPE PDGFR_beta 12062403
LTP
1.00
 PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2		 -
0.75
 - medium
S 1104 CPAPRAEAEDSFL         GRK-2 15271984
LTP
0.00
 - -
0.66
 - medium

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