Substrate: Poly [ADP-ribose] polymerase 1
Seq-ID: P09874 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16977   P53_HUMAN
MINT-48090   IKKB_HUMAN
MINT-48220   NEMO_HUMAN
MINT-48757   NFKB2_HUMAN
MINT-7294936   XRCC1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
NAD+ ADP-ribosyltransferase activity,
DNA binding,
identical protein binding,
transcription factor binding,
zinc ion binding,
protein N-terminus binding		 transcription factor complex,
nucleolus,
nuclear envelope		 transcription from RNA polymerase II promoter,
regulation of transcription,
protein amino acid ADP-ribosylation,
cellular response to insulin stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 41 DSLRMAIMVQSPMFDGKVPHW - 18669648
HTP
1.00
 - zf-PARP
0.32
 --
S 179 ELGFRPEYSASQLKGFSLLAT - 17525332
HTP
0.06
 - zf-PARP
0.34
 --
T 368 PPETSASVAATPPPSTASAPA - 18669648
HTP
0.40
 - -
0.65
 --
S 372 SASVAATPPPSTASAPAAVNS - 18669648
HTP
0.17
 - -
0.62
 --
S 782 EVAYSLLRGGSDDSSKDPIDV - 18669648
HTP
0.52
 - PARP_reg
0.36
 2RD6 63.11%

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