Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Retinoic acid receptor alpha (Nuclear hormone receptor family)

Seq-ID:

P10276 [Homo sapiens]

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Interaction Network(s):

External Source(s):

MINT Interaction(s):

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GO-Terms:

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Molecular Function	Cellular Component	Biological Process
protein heterodimerization activity, retinoic acid binding, retinoic acid receptor activity, chromatin DNA binding, protein domain specific binding, transcription corepressor activity, enzyme binding, retinoic acid-responsive element binding, transcription coactivator activity, zinc ion binding, receptor binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity	cytoplasm, cell surface, nucleus	negative regulation of granulocyte differentiation, negative regulation of tumor necrosis factor production, positive regulation of cell cycle, response to estradiol stimulus, positive regulation of gene-specific transcription, positive regulation of interleukin-5 production, positive regulation of binding, cellular response to estrogen stimulus, estrogen receptor signaling pathway, cellular response to retinoic acid, negative regulation of interferon-gamma production, positive regulation of transcription from RNA polymerase II promoter, apoptotic cell clearance, positive regulation of interleukin-13 production, negative regulation of gene-specific transcription, positive regulation of interleukin-4 production, positive regulation of cell proliferation, protein amino acid phosphorylation, transcription, positive regulation of T-helper 2 cell differentiation

Conservation:

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Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	77	SSEEIVPSPPSPPPLPRIYKP	CDK7	9230306	LTP	0.97	-	-	0.48	-	-
T	181	KPECSESYTLTPEVGELIEKV	-	15657432	LTP	0.22	-	-	0.27	-	-
S	445	GGLAPPPGSCSPSLSPSSNRS	-	15657432	LTP	0.31	-	-	0.90	-	-
S	461	SSNRSSPATHSP	-	15657432	LTP	0.21	-	-	0.68	-	-