Substrate: p53 (Cellular tumor antigen p53)
Seq-ID: P10361 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
RNA polymerase II transcription factor activity,
ubiquitin protein ligase binding,
DNA strand annealing activity,
copper ion binding,
ATP binding,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
transcription repressor activity,
sequence-specific DNA binding,
protein C-terminus binding		 cytosol,
transcription factor complex,
nucleolus,
soluble fraction,
endoplasmic reticulum,
mitochondrion,
chromatin		 positive regulation of gene-specific transcription from RNA polymerase II promoter,
response to amino acid stimulus,
response to oxidative stress,
response to drug,
response to vitamin B3,
cell cycle,
positive regulation of apoptosis,
negative regulation of smooth muscle cell proliferation,
response to cytokine stimulus,
response to X-ray,
response to tumor cell,
regulation of intracellular pH,
response to caffeine,
nucleotide-excision repair,
response to retinoic acid,
wound healing,
multicellular organismal development,
response to hyperoxia,
positive regulation of leukocyte migration,
response to metal ion,
response to UV,
transcription,
negative regulation of cell growth,
positive regulation of cell cycle,
activation of caspase activity by cytochrome c,
cell aging
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 6      MEDSQSDMSIELPLSQ CK1_group 7862459
LTP
0.18
 MOD_CK1_1
 - P53_TAD
0.73
 - medium
S 9   MEDSQSDMSIELPLSQETF CK1_group 7862459
LTP
0.75
 MOD_CK1_1
 - P53_TAD
0.65
 - medium
S 15 QSDMSIELPLSQETFSCLWKL DNA-PK 7862459
LTP
1.00
 MOD_PIKK_1
 - P53_TAD
0.35
 - medium
S 39 DDILPTTATGSPNSMEDLFLP - 7862459
LTP
0.75
 - -
0.59
 - medium
S 313 KRALPTSTSSSPQQKKKPLDG CDK1 7862459
LTP
0.95
 - -
0.78
 - medium

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