Substrate: Bcr (Breakpoint cluster region protein)
Seq-ID: P11274 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-69534   AT2B1_HUMAN
MINT-69536   CLH1_HUMAN
MINT-69537   CFTR_HUMAN
MINT-69540   ZO2_HUMAN
MINT-69542   RGS12_HUMAN
MINT-4961172   AFAD_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
protein serine/threonine kinase activity,
ATP binding,
GTPase activator activity		 intracellular protein amino acid phosphorylation,
signal transduction,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 122 EPEARPDGEGSPGKARPGTAR - 18220336
HTP
0.35
 - -
0.96
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG Fes 8955135
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG Fes 10405761
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG - 12522270
HTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG - 9178913
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG - 12124177
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG - 9407116
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG Abl 16912036
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG HCK 16912036
LTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 177 QPGADAEKPFYVNVEFHHERG - 18083107
HTP
0.75
 ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2		 -
0.68
 - medium
Y 231 SSVGDASRPPYRGRSSESSCG - 16497976
HTP
0.00
 - -
0.75
 - medium
Y 246 SESSCGVDGDYEDAELNPRFL Fes 8955135
LTP
1.00
 ABL1 SH2;
GRB10 SH2;
GRB2 SH2		 -
0.57
 - medium
Y 276 GSRPPWPPLEYQPYQSIYVGG Fes 8955135
LTP
0.00
 ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2		 -
0.58
 - medium
Y 279 PPWPPLEYQPYQSIYVGGMME Fes 8955135
LTP
1.00
 ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2		 -
0.58
 - medium
Y 283 PLEYQPYQSIYVGGMMEGEGK Fes 8955135
LTP
1.00
 ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2		 -
0.61
 - medium
T 310 QSTSEQEKRLTWPRRSYSPRS - 12522270
HTP
0.58
 - -
0.68
 - medium
Y 328 PRSFEDCGGGYTPDCSSNENL - 9467953
LTP
0.58
 GRB10 SH2 -
0.56
 - medium
Y 360 SSRVSPSPTTYRMFRDKSRSP Abl 9467953
LTP
0.53
 GRB10 SH2 -
0.77
 - medium
Y 436 ADGSFGTPPGYGCAADRAEEQ - 16497976
HTP
0.81
 GRB10 SH2 -
0.71
 - medium
S 459 HQDGLPYIDDSPSSSPHLSSK - 12522270
HTP
0.50
 - -
0.72
 - medium
S 459 HQDGLPYIDDSPSSSPHLSSK - 17081983
HTP
0.50
 - -
0.72
 - medium
S 459 HQDGLPYIDDSPSSSPHLSSK - 18088087
HTP
0.50
 - -
0.72
 - medium
S 459 HQDGLPYIDDSPSSSPHLSSK - 18669648
HTP
0.50
 - -
0.72
 - medium
S 463 LPYIDDSPSSSPHLSSKGRGS - 12522270
HTP
1.00
 - -
0.71
 - medium
S 463 LPYIDDSPSSSPHLSSKGRGS - 18669648
HTP
1.00
 - -
0.71
 - medium
Y 591 FQKLASQLGVYRAFVDNYGVA - 12522270
HTP
1.00
 - RhoGEF
0.08
 - medium
Y 598 LGVYRAFVDNYGVAMEMAEKC - 16497976
HTP
1.00
 - RhoGEF
0.13
 - medium
Y 644 TTKNSLETLLYKPVDRVTRST - 12522270
HTP
1.00
 - RhoGEF
0.34
 - medium
S 1264 AIPAPDSKRQSILFSTEV    - 15144186
HTP
1.00
 - -
0.29
 - medium
S 1264 AIPAPDSKRQSILFSTEV    CK2_alpha 11084041
LTP
1.00
 - -
0.29
 - medium

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