Statistics: | ||
Instances | 42.914 | |
Kinases | 299 | |
References | 3.657 | |
Sequences | 11.224 | |
Substrates | 8.698 |
Substrate: | DNA topoisomerase II, alpha (DNA topoisomerase II alpha) |
---|---|
Seq-ID: | P11388 [Homo sapiens] |
Download: | fasta csv |
Interaction Network(s): | - |
External Source(s): | |
MINT Interaction(s): | |
GO-Terms: | [show] |
Conservation: | |
Click on table headers for sorting |
Res. | Pos. | Sequence | Kinase | PMID | Src | Cons. | ELM | Binding Domain | SMART/Pfam | IUPRED score | PDB | P3D Acc. |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S | 4 | MEVSPLQPVNENMQ | - | 17081983 | HTP |
0.48 |
- | - | 0.48 |
- | - |
|
S | 29 | KKNEDAKKRLSVERIYQKKTQ | PKC_group | 7499337 | LTP |
1.00 |
- | - | 0.40 |
1ZXM |
59.02% |
|
S | 29 | KKNEDAKKRLSVERIYQKKTQ | - | 17081983 | HTP |
1.00 |
- | - | 0.40 |
1ZXM |
59.02% |
|
S | 1106 | KVPDEEENEESDNEKETEKSD | - | 16565220 | HTP |
0.28 |
- | TOP4c | 0.88 |
- | - |
|
S | 1106 | KVPDEEENEESDNEKETEKSD | - | 17081983 | HTP |
0.28 |
- | TOP4c | 0.88 |
- | - |
|
S | 1106 | KVPDEEENEESDNEKETEKSD | - | 17287340 | HTP |
0.28 |
- | TOP4c | 0.88 |
- | - |
|
S | 1106 | KVPDEEENEESDNEKETEKSD | - | 18669648 | HTP |
0.28 |
- | TOP4c | 0.88 |
- | - |
|
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | CDK1 | 7635160 | LTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | MAPK1 | 7635160 | LTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | MAPK3 | 7635160 | LTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | - | 16565220 | HTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | - | 17081983 | HTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | - | 16964243 | HTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | - | 18220336 | HTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
S | 1213 | KKTQMAEVLPSPRGQRVIPRI | - | 18669648 | HTP |
0.91 |
MOD_ProDKin_1 |
- | - | 0.70 |
- | - |
T | 1244 | KNKKKIKNENTEGSPQEDGVE | - | 18669648 | HTP |
0.10 |
- | - | 0.83 |
- | - |
|
S | 1247 | KKIKNENTEGSPQEDGVELEG | CDK1 | 7635160 | LTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1247 | KKIKNENTEGSPQEDGVELEG | MAPK1 | 7635160 | LTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1247 | KKIKNENTEGSPQEDGVELEG | MAPK3 | 7635160 | LTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1247 | KKIKNENTEGSPQEDGVELEG | - | 16565220 | HTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1247 | KKIKNENTEGSPQEDGVELEG | - | 17081983 | HTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1247 | KKIKNENTEGSPQEDGVELEG | - | 17287340 | HTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1247 | KKIKNENTEGSPQEDGVELEG | - | 18669648 | HTP |
0.20 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 1295 | IKKGKKRNPWSDSESDRSSDE | - | 16565220 | HTP |
0.83 |
- | - | 0.83 |
- | - |
|
S | 1297 | KGKKRNPWSDSESDRSSDESN | - | 16565220 | HTP |
0.46 |
- | - | 0.83 |
- | - |
|
T | 1327 | PRRAATKTKFTMDLDSDEDFS | - | 18669648 | HTP |
0.67 |
- | - | 0.70 |
- | - |
|
S | 1332 | TKTKFTMDLDSDEDFSDFDEK | - | 17081983 | HTP |
0.14 |
- | - | 0.64 |
- | - |
|
S | 1332 | TKTKFTMDLDSDEDFSDFDEK | - | 18669648 | HTP |
0.14 |
- | - | 0.64 |
- | - |
|
S | 1337 | TMDLDSDEDFSDFDEKTDDED | - | 17081983 | HTP |
0.47 |
- | - | 0.68 |
- | - |
|
S | 1337 | TMDLDSDEDFSDFDEKTDDED | - | 18669648 | HTP |
0.47 |
- | - | 0.68 |
- | - |
|
T | 1343 | DEDFSDFDEKTDDEDFVPSDA | CK2_group | 9804834 | LTP |
0.12 |
MOD_CK2_1 |
- | - | 0.73 |
- | - |
T | 1343 | DEDFSDFDEKTDDEDFVPSDA | PKC_beta | 7499337 | LTP |
0.12 |
MOD_CK2_1 |
- | - | 0.73 |
- | - |
T | 1343 | DEDFSDFDEKTDDEDFVPSDA | - | 17081983 | HTP |
0.12 |
MOD_CK2_1 |
- | - | 0.73 |
- | - |
T | 1343 | DEDFSDFDEKTDDEDFVPSDA | - | 18669648 | HTP |
0.12 |
MOD_CK2_1 |
- | - | 0.73 |
- | - |
S | 1351 | EKTDDEDFVPSDASPPKTKTS | - | 16565220 | HTP |
0.16 |
- | - | 0.86 |
- | - |
|
S | 1351 | EKTDDEDFVPSDASPPKTKTS | - | 17081983 | HTP |
0.16 |
- | - | 0.86 |
- | - |
|
S | 1351 | EKTDDEDFVPSDASPPKTKTS | - | 18669648 | HTP |
0.16 |
- | - | 0.86 |
- | - |
|
S | 1354 | DDEDFVPSDASPPKTKTSPKL | CDK1 | 7635160 | LTP |
0.04 |
MOD_CDK_SPxK_1 |
- | - | 0.87 |
- | - |
S | 1354 | DDEDFVPSDASPPKTKTSPKL | MAPK1 | 7635160 | LTP |
0.04 |
MOD_CDK_SPxK_1 |
- | - | 0.87 |
- | - |
S | 1354 | DDEDFVPSDASPPKTKTSPKL | MAPK3 | 7635160 | LTP |
0.04 |
MOD_CDK_SPxK_1 |
- | - | 0.87 |
- | - |
S | 1354 | DDEDFVPSDASPPKTKTSPKL | - | 16565220 | HTP |
0.04 |
MOD_CDK_SPxK_1 |
- | - | 0.87 |
- | - |
S | 1354 | DDEDFVPSDASPPKTKTSPKL | - | 17081983 | HTP |
0.04 |
MOD_CDK_SPxK_1 |
- | - | 0.87 |
- | - |
S | 1354 | DDEDFVPSDASPPKTKTSPKL | - | 18669648 | HTP |
0.04 |
MOD_CDK_SPxK_1 |
- | - | 0.87 |
- | - |
T | 1358 | FVPSDASPPKTKTSPKLSNKE | - | 18669648 | HTP |
0.04 |
- | - | 0.87 |
- | - |
|
S | 1361 | SDASPPKTKTSPKLSNKELKP | CDK1 | 7635160 | LTP |
0.24 |
MOD_ProDKin_1 |
- | - | 0.89 |
- | - |
S | 1361 | SDASPPKTKTSPKLSNKELKP | MAPK1 | 7635160 | LTP |
0.24 |
MOD_ProDKin_1 |
- | - | 0.89 |
- | - |
S | 1361 | SDASPPKTKTSPKLSNKELKP | MAPK3 | 7635160 | LTP |
0.24 |
MOD_ProDKin_1 |
- | - | 0.89 |
- | - |
S | 1374 | LSNKELKPQKSVVSDLEADDV | - | 17081983 | HTP |
0.27 |
- | - | 0.77 |
- | - |
|
S | 1374 | LSNKELKPQKSVVSDLEADDV | - | 16964243 | HTP |
0.27 |
- | - | 0.77 |
- | - |
|
S | 1374 | LSNKELKPQKSVVSDLEADDV | - | 17287340 | HTP |
0.27 |
- | - | 0.77 |
- | - |
|
S | 1374 | LSNKELKPQKSVVSDLEADDV | - | 18669648 | HTP |
0.27 |
- | - | 0.77 |
- | - |
|
S | 1377 | KELKPQKSVVSDLEADDVKGS | - | 9761967 | LTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1377 | KELKPQKSVVSDLEADDVKGS | CK2_group | 7961967 | LTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1377 | KELKPQKSVVSDLEADDVKGS | CK2_alpha | 7961967 | LTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1377 | KELKPQKSVVSDLEADDVKGS | - | 17081983 | HTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1377 | KELKPQKSVVSDLEADDVKGS | - | 16964243 | HTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1377 | KELKPQKSVVSDLEADDVKGS | - | 17287340 | HTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1377 | KELKPQKSVVSDLEADDVKGS | - | 18669648 | HTP |
0.43 |
MOD_CK2_1 |
- | - | 0.77 |
- | - |
S | 1387 | SDLEADDVKGSVPLSSSPPAT | - | 16565220 | HTP |
0.66 |
- | - | 0.83 |
- | - |
|
S | 1391 | ADDVKGSVPLSSSPPATHFPD | - | 18669648 | HTP |
0.21 |
- | - | 0.84 |
- | - |
|
S | 1392 | DDVKGSVPLSSSPPATHFPDE | - | 18669648 | HTP |
0.33 |
- | - | 0.85 |
- | - |
|
S | 1393 | DVKGSVPLSSSPPATHFPDET | CDK1 | 7635160 | LTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
S | 1393 | DVKGSVPLSSSPPATHFPDET | MAPK1 | 7635160 | LTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
S | 1393 | DVKGSVPLSSSPPATHFPDET | MAPK3 | 7635160 | LTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
S | 1393 | DVKGSVPLSSSPPATHFPDET | - | 16565220 | HTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
S | 1393 | DVKGSVPLSSSPPATHFPDET | - | 17081983 | HTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
S | 1393 | DVKGSVPLSSSPPATHFPDET | - | 18220336 | HTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
S | 1393 | DVKGSVPLSSSPPATHFPDET | - | 18669648 | HTP |
0.19 |
MOD_ProDKin_1 |
- | - | 0.86 |
- | - |
T | 1397 | SVPLSSSPPATHFPDETEITN | - | 18669648 | HTP |
0.08 |
- | - | 0.86 |
- | - |
|
S | 1449 | KGTKRDPALNSGVSQKPDPAK | - | 18669648 | HTP |
0.51 |
- | DTHCT | 0.90 |
- | - |
|
S | 1452 | KRDPALNSGVSQKPDPAKTKN | - | 18669648 | HTP |
0.62 |
- | DTHCT | 0.90 |
- | - |
|
S | 1469 | KTKNRRKRKPSTSDDSDSNFE | - | 18669648 | HTP |
0.16 |
- | DTHCT | 0.85 |
- | - |
|
T | 1470 | TKNRRKRKPSTSDDSDSNFEK | - | 18669648 | HTP |
0.08 |
- | DTHCT | 0.82 |
- | - |
|
S | 1471 | KNRRKRKPSTSDDSDSNFEKI | - | 18669648 | HTP |
0.53 |
- | DTHCT | 0.81 |
- | - |
|
S | 1474 | RKRKPSTSDDSDSNFEKIVSK | - | 15302935 | HTP |
0.85 |
- | DTHCT | 0.75 |
- | - |
|
S | 1474 | RKRKPSTSDDSDSNFEKIVSK | - | 18669648 | HTP |
0.85 |
- | DTHCT | 0.75 |
- | - |
|
S | 1491 | IVSKAVTSKKSKGESDDFHMD | - | 18669648 | HTP |
0.42 |
- | DTHCT | 0.63 |
- | - |
|
S | 1495 | AVTSKKSKGESDDFHMDFDSA | - | 18669648 | HTP |
0.34 |
- | DTHCT | 0.66 |
- | - |
|
S | 1504 | ESDDFHMDFDSAVAPRAKSVR | - | 18220336 | HTP |
0.34 |
- | DTHCT | 0.68 |
- | - |
|
S | 1504 | ESDDFHMDFDSAVAPRAKSVR | - | 18669648 | HTP |
0.34 |
- | DTHCT | 0.68 |
- | - |
|
S | 1525 | AKKPIKYLEESDEDDLF | - | 9761967 | LTP |
0.95 |
- | - | 0.51 |
- | - |
|
S | 1525 | AKKPIKYLEESDEDDLF | CK2_group | 7961967 | LTP |
0.95 |
- | - | 0.51 |
- | - |
|
S | 1525 | AKKPIKYLEESDEDDLF | CK2_alpha | 7961967 | LTP |
0.95 |
- | - | 0.51 |
- | - |
|
S | 1525 | AKKPIKYLEESDEDDLF | - | 17081983 | HTP |
0.95 |
- | - | 0.51 |
- | - |
|
S | 1525 | AKKPIKYLEESDEDDLF | - | 16964243 | HTP |
0.95 |
- | - | 0.51 |
- | - |
|
S | 1525 | AKKPIKYLEESDEDDLF | - | 18669648 | HTP |
0.95 |
- | - | 0.51 |
- | - |