Substrate: Amyloid beta A4 protein (Cell surface receptor)
Seq-ID: P12023 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-18945   NUMB_MOUSE
MINT-45971   JIP1_HUMAN
MINT-7894126   DLG4_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
serine-type endopeptidase inhibitor activity,
DNA binding,
metal ion binding,
heparin binding		 cytoplasmic vesicle,
neuromuscular junction,
coated pit,
integral to membrane,
Golgi apparatus,
apical part of cell,
spindle midzone,
axon,
perinuclear region of cytoplasm,
ciliary rootlet		 dendrite development,
smooth endoplasmic reticulum calcium ion homeostasis,
G2 phase of mitotic cell cycle,
positive regulation of mitotic cell cycle,
regulation of multicellular organism growth,
ionotropic glutamate receptor signaling pathway,
mRNA polyadenylation,
collateral sprouting in the absence of injury,
adult locomotory behavior,
extracellular matrix organization,
Notch signaling pathway,
regulation of translation,
visual learning,
synaptic growth at neuromuscular junction,
axon midline choice point recognition,
cell adhesion,
neuron remodeling,
neuromuscular process controlling balance,
positive regulation of transcription from RNA polymerase II promoter,
mating behavior,
endocytosis,
forebrain development,
axon cargo transport,
cellular copper ion homeostasis,
protein amino acid phosphorylation,
suckling behavior,
regulation of synapse structure and activity,
regulation of epidermal growth factor receptor activity
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 743 HGVVEVDAAVTPEERHLSKMQ - 14722157
LTP
1.00
 - APP_amyloid
0.46
 --
Y 757 RHLSKMQQNGYENPTYKFFEQ - 11877420
LTP
1.00
 - APP_amyloid
0.38
 --

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