Substrate: Src (Proto-oncogene tyrosine-protein kinase Src)
Seq-ID: P12931 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14765   DDR2_HUMAN
MINT-15459   CAV1_HUMAN
MINT-46002   CTNB1_MOUSE
MINT-50376   RASH_HUMAN
MINT-62340   KPCD_HUMAN
MINT-62342   CDCP1_HUMAN
MINT-65953   DYN1_HUMAN
MINT-65954   DYN2_HUMAN
MINT-68512   PDC6I_HUMAN
MINT-74753   ERBB3_HUMAN
MINT-2792760   PAK2_HUMAN
MINT-2793013   ADA15_HUMAN
MINT-2840132   TLR3_HUMAN
MINT-3381308   FAK1_HUMAN
MINT-3381360   FYN_HUMAN
MINT-4051815   ADRB2_HUMAN
MINT-4961196   AFAD_HUMAN
MINT-4980122   SNIP_MOUSE
MINT-5210599   SNIP_HUMAN
MINT-6539730   CBL_HUMAN
MINT-6771405   FAK1_MOUSE
MINT-6794909   ACTS_HUMAN
MINT-6795322   ACTN1_HUMAN
MINT-6795447   PTN1_HUMAN
MINT-7035260   HNRPK_HUMAN
MINT-7040283   CBLB_HUMAN
MINT-7104422   BCAR1_HUMAN
MINT-7145938   RL10_HUMAN
MINT-7244986   ASAP1_HUMAN
MINT-7244998   FANCA_HUMAN
MINT-7245022   PHAR2_HUMAN
MINT-7245034   ABL1_HUMAN
MINT-7245058   DLGP4_HUMAN
MINT-7245070   SNX17_HUMAN
MINT-7245106   RTN4_HUMAN
MINT-7245118   ASAP2_HUMAN
MINT-7245142   E41L3_HUMAN
MINT-7245154   ICAL_HUMAN
MINT-7245214   FCG2B_HUMAN
MINT-7245226   FCG2C_HUMAN
MINT-7245334   SHAN2_HUMAN
MINT-7245346   SHRM2_HUMAN
MINT-7245358   DNLI3_HUMAN
MINT-7245370   EIF3D_HUMAN
MINT-7245406   HCN2_HUMAN
MINT-7245490   CKAP5_HUMAN
MINT-7245502   M4K1_HUMAN
MINT-7245538   RPP38_HUMAN
MINT-7245562   SP1_HUMAN
MINT-7245574   DOCK1_HUMAN
MINT-7245586   RLGPB_HUMAN
MINT-7245598   ABL2_HUMAN
MINT-7245610   CELR2_HUMAN
MINT-7245622   SOS1_HUMAN
MINT-7245634   AKAP6_HUMAN
MINT-7245670   DPOD1_HUMAN
MINT-7245682   DAG1_HUMAN
MINT-7245694   SNX3_HUMAN
MINT-7245730   KI67_HUMAN
MINT-7245742   CD97_HUMAN
MINT-7245754   RPGF1_HUMAN
MINT-7245778   ACAP1_HUMAN
MINT-7245790   PRIC3_HUMAN
MINT-7245814   AKAP2_HUMAN
MINT-7245826   RRAS_HUMAN
MINT-7296136   P85A_HUMAN
MINT-7296149   ACTB_HUMAN
MINT-7306598   LCP2_HUMAN
MINT-7552515   PTPRA_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3/SH2 adaptor activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
integrin binding,
SH2 domain binding		 caveola,
cytosol		 protein amino acid phosphorylation,
regulation of bone resorption,
signal complex assembly,
regulation of vascular permeability,
response to interleukin-1,
interspecies interaction between organisms,
Ras protein signal transduction,
positive regulation of integrin activation,
intracellular protein kinase cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 12 GSNKSKPKDASQRRRSLEPAE - 2136766
LTP
0.21
 - -
0.89
 --
S 17 KPKDASQRRRSLEPAENVHGA PKA_group 11804588
LTP
0.24
 MOD_PKA_1
 - -
0.88
 --
S 17 KPKDASQRRRSLEPAENVHGA - 17081983
HTP
0.24
 MOD_PKA_1
 - -
0.88
 --
S 17 KPKDASQRRRSLEPAENVHGA - 17192257
HTP
0.24
 MOD_PKA_1
 - -
0.88
 --
S 17 KPKDASQRRRSLEPAENVHGA - 18088087
HTP
0.24
 MOD_PKA_1
 - -
0.88
 --
S 69 AEPKLFGGFNSSDTVTSPQRA - 17192257
HTP
0.41
 - -
0.61
 --
T 74 FGGFNSSDTVTSPQRAGPLAG - 18088087
HTP
0.52
 - -
0.62
 --
S 75 GGFNSSDTVTSPQRAGPLAGG CDK_group 10544291
LTP
0.14
 MOD_CDK_SPxK_1
 - -
0.64
 --
S 75 GGFNSSDTVTSPQRAGPLAGG CDK5 10544291
LTP
0.14
 MOD_CDK_SPxK_1
 - -
0.64
 --
S 75 GGFNSSDTVTSPQRAGPLAGG - 17192257
HTP
0.14
 MOD_CDK_SPxK_1
 - -
0.64
 --
S 97 TTFVALYDYESRTETDLSFKK - 1713455
LTP
0.16
 - SH3
0.32
 1FMK 36.07%
Y 216 KIRKLDSGGFYITSRTQFNSL SRC 12753909
LTP
1.00
 - SH2
0.20
 1FMK 20.09%
Y 338 LYAVVSEEPIYIVTEYMSKGS SRC 7578094
LTP
1.00
 - TyrKc
0.07
 1FMK 17.03%
Y 419 GLARLIEDNEYTARQGAKFPI - 6273838
LTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 419 GLARLIEDNEYTARQGAKFPI - 11278940
LTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 419 GLARLIEDNEYTARQGAKFPI SRC 7578094
LTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 419 GLARLIEDNEYTARQGAKFPI SRC 11804588
LTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 419 GLARLIEDNEYTARQGAKFPI SRC 15489898
LTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 419 GLARLIEDNEYTARQGAKFPI - 17081983
HTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 419 GLARLIEDNEYTARQGAKFPI - 17192257
HTP
1.00
 CBL PTB;
Csk SH2;
Src SH2		 TyrKc
0.17
 1Y57 26.20%
Y 439 IKWTAPEAALYGRFTIKSDVW - 18083107
HTP
0.85
 - TyrKc
0.08
 1FMK 64.63%
Y 530 EDYFTSTEPQYQPGENL     - 3103926
LTP
0.94
 MOD_TYR_CSK
 Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2		 -
0.46
 1FMK 18.34%
Y 530 EDYFTSTEPQYQPGENL     Csk 12468645
LTP
0.94
 MOD_TYR_CSK
 Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2		 -
0.46
 1FMK 18.34%
Y 530 EDYFTSTEPQYQPGENL     - 12387813
LTP
0.94
 MOD_TYR_CSK
 Csk SH2;
Fyn SH2;
Lck SH2;
PIK3R1 SH2;
Src SH2		 -
0.46
 1FMK 18.34%

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