Substrate: Ku70 (DNA repair protein)
Seq-ID: P12956 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-60809   Z512B_HUMAN
MINT-61696   SMAD3_HUMAN
MINT-63311   FMNL_HUMAN
MINT-63409   RLA1_HUMAN
MINT-63486   PECA1_HUMAN
MINT-63718   VATE1_HUMAN
MINT-63953   RRAS2_HUMAN
MINT-63980   1433Z_HUMAN
MINT-64134   SNTA1_HUMAN
MINT-65113   ACD_HUMAN
MINT-65145   CDCA5_HUMAN
MINT-65245   ARAP1_HUMAN
MINT-65249   CRML_HUMAN
MINT-73060   WBP4_HUMAN
MINT-3978316   HD_HUMAN
MINT-3979927   CLH1_HUMAN
MINT-4051792   KU86_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP-dependent DNA helicase activity,
5`-deoxyribose-5-phosphate lyase activity,
protein C-terminus binding,
transcription activator activity,
double-stranded DNA binding,
ATP binding,
promoter binding		 membrane fraction,
Ku70:Ku80 complex,
nuclear telomere cap complex,
transcription factor complex,
DNA-dependent protein kinase-DNA ligase 4 complex		 double-strand break repair via nonhomologous end joining,
provirus integration,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
DNA ligation,
telomere maintenance,
initiation of viral infection
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 6      MSGWESYYKTEGDEEA - 10026262
LTP
0.10
 - -
0.50
 --
S 6      MSGWESYYKTEGDEEA - 15941674
LTP
0.10
 - -
0.50
 --
S 37 SGDYKYSGRDSLIFLVDASKA - 15302935
HTP
1.00
 - Ku_N
0.16
 1JEQ 0.00%
S 222 DISLFYRDIISIAEDEDLRVH - 16097034
HTP
0.93
 - Ku_N
0.07
 1JEQ 17.21%

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