Substrate: INF-alpha REC (Interferon receptor)
Seq-ID: P17181 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
MINT-73134   TYK2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
type I interferon receptor activity integral to plasma membrane blood coagulation,
JAK-STAT cascade,
response to virus
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 466 AAKVFLRCINYVFFPSLKPSS Tyk2 8605876
LTP
1.00
 STAT1 SH2;
STAT2 SH2;
STAT3 SH2;
TYK2 SH2		 -
0.03
 - low
Y 466 AAKVFLRCINYVFFPSLKPSS Tyk2 8700538
LTP
1.00
 STAT1 SH2;
STAT2 SH2;
STAT3 SH2;
TYK2 SH2		 -
0.03
 - low
Y 481 SLKPSSSIDEYFSEQPLKNLL Tyk2 7526154
LTP
1.00
 STAT2 SH2;
TYK2 SH2		 -
0.24
 - low
S 495 QPLKNLLLSTSEEQIEKCFII - 15659558
HTP
1.00
 - -
0.14
 - low
S 535 KKYSSQTSQDSGNYSNEDESE - 15337770
LTP
1.00
 - -
0.70
 - low

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