Substrate: PKC alpha (Serine/threonine kinase)
Seq-ID: P17252 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-62532   RBP1_HUMAN
MINT-2490678   RAC1_HUMAN
MINT-2833162   BRAF_HUMAN
MINT-2833275   KPCE_HUMAN
MINT-2833291   KS6A2_HUMAN
MINT-3973484   NCF1_HUMAN
MINT-4298329   NUMB_DROME
MINT-4300836   INADL_HUMAN
MINT-4507294   JAK1_HUMAN
MINT-4507312   TYK2_HUMAN
MINT-4507332   IF2A_HUMAN
MINT-4507367   JAK2_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone kinase activity (H3-T6 specific),
ATP binding,
enzyme binding,
zinc ion binding		 plasma membrane,
cytosol,
endoplasmic reticulum		 induction of apoptosis by extracellular signals,
response to interleukin-1
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 195 PMDPNGLSDPYVKLKLIPDPK - 18083107
HTP
0.91
 - C2
0.45
 3GPE 6.11%
S 226 RSTLNPQWNESFTFKLKPSDK - 17081983
HTP
0.23
 - C2
0.45
 3GPE 70.49%
S 226 RSTLNPQWNESFTFKLKPSDK - 17192257
HTP
0.23
 - C2
0.45
 3GPE 70.49%
S 319 KLGPAGNKVISPSEDRKQPSN - 17081983
HTP
0.18
 - -
0.68
 --
S 319 KLGPAGNKVISPSEDRKQPSN - 16964243
HTP
0.18
 - -
0.68
 --
S 319 KLGPAGNKVISPSEDRKQPSN - 18088087
HTP
0.18
 - -
0.68
 --
T 497 EHMMDGVTTRTFCGTPDYIAP - 17192257
HTP
1.00
 - S_TKc
0.20
 --
T 501 DGVTTRTFCGTPDYIAPEIIA - 17192257
HTP
1.00
 - S_TKc
0.14
 --
T 638 KFFTRGQPVLTPPDQLVIANI - 15314172
LTP
0.92
 - S_TK_X
0.36
 --
T 638 KFFTRGQPVLTPPDQLVIANI - 14581488
LTP
0.92
 - S_TK_X
0.36
 --
T 638 KFFTRGQPVLTPPDQLVIANI - 17192257
HTP
0.92
 - S_TK_X
0.36
 --
S 657 NIDQSDFEGFSYVNPQFVHPI PKC_alpha 8856079
LTP
0.84
 - S_TK_X
0.23
 --
Y 658 IDQSDFEGFSYVNPQFVHPIL SYK 12881490
LTP
0.55
 - S_TK_X
0.23
 --
Y 658 IDQSDFEGFSYVNPQFVHPIL - 17192257
HTP
0.55
 - S_TK_X
0.23
 --

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