Substrate: Nuclear factor NF-kappa-B p105 subunit (Nuclear factor NF-kappa-B p105 subunit)
Seq-ID: P19838 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-47827   M3K8_HUMAN
MINT-47861   IKBB_HUMAN
MINT-48545   TPR_HUMAN
MINT-48546   KCRB_HUMAN
MINT-48547   CLH1_HUMAN
MINT-48555   VIME_HUMAN
MINT-48556   ADT3_HUMAN
MINT-48557   DESP_HUMAN
MINT-48560   JIP4_HUMAN
MINT-48561   COPB2_HUMAN
MINT-48636   BAG2_HUMAN
MINT-48638   NEMO_HUMAN
MINT-48639   HS71L_HUMAN
MINT-48640   GRP78_HUMAN
MINT-48641   HSP7C_HUMAN
MINT-48642   HNRPF_HUMAN
MINT-48643   IKKA_HUMAN
MINT-48644   ADT2_HUMAN
MINT-48645   GRP75_HUMAN
MINT-48646   RUVB2_HUMAN
MINT-48648   IMA3_HUMAN
MINT-48650   DNJA1_HUMAN
MINT-48651   IMA4_HUMAN
MINT-48653   C1QBP_HUMAN
MINT-48654   EF1A2_HUMAN
MINT-48655   MATR3_HUMAN
MINT-48656   IKBA_HUMAN
MINT-48659   MYH10_HUMAN
MINT-48660   PYR1_HUMAN
MINT-48663   ACTG_HUMAN
MINT-48665   STUB1_HUMAN
MINT-48666   REL_HUMAN
MINT-48669   TBB6_HUMAN
MINT-48670   CALM_HUMAN
MINT-48671   NONO_HUMAN
MINT-48672   TBB5_HUMAN
MINT-48673   TBB4_HUMAN
MINT-48675   K1967_HUMAN
MINT-48677   DNJA3_HUMAN
MINT-48678   MYH9_HUMAN
MINT-48679   RS8_HUMAN
MINT-48680   SFPQ_HUMAN
MINT-48682   HS90A_HUMAN
MINT-48684   PRKDC_HUMAN
MINT-48685   MYL6_HUMAN
MINT-48687   HNRPM_HUMAN
MINT-48688   HS90B_HUMAN
MINT-48689   ML12A_HUMAN
MINT-48724   NFKB2_HUMAN
MINT-48996   RELB_HUMAN
MINT-50169   HDAC1_HUMAN
MINT-7023862   CTNB1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
promoter binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 cytosol,
I-kappaB/NF-kappaB complex,
nucleoplasm		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription from RNA polymerase II promoter,
positive regulation of transcription,
negative regulation of cellular protein metabolic process,
apoptosis,
anti-apoptosis,
negative regulation of cholesterol transport,
membrane protein intracellular domain proteolysis,
positive regulation of lipid storage,
signal transduction,
inflammatory response,
positive regulation of macrophage derived foam cell differentiation,
negative regulation of vitamin D biosynthetic process,
negative regulation of calcidiol 1-monooxygenase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 337 ASVFVQLRRKSDLETSEPKPF PKA_group 12947093
LTP
1.00
 MOD_PKA_1
 - IPT
0.42
 1U3J 67.21%
S 337 ASVFVQLRRKSDLETSEPKPF PKA_group 15642694
LTP
1.00
 MOD_PKA_1
 - IPT
0.42
 1U3J 67.21%
S 893 EAIEVIQAASSPVKTTSQAHS - 8522173
LTP
0.88
 - -
0.46
 --
S 903 SPVKTTSQAHSLPLSPASTRQ GSK-3_beta 12871932
LTP
 - MOD_GSK3_1
 - -
0.66
 --
S 903 SPVKTTSQAHSLPLSPASTRQ - 18669648
HTP
 - MOD_GSK3_1
 - -
0.66
 --
S 907 TTSQAHSLPLSPASTRQQIDE GSK-3_beta 12871932
LTP
 - MOD_GSK3_1
 - -
0.62
 --
S 907 TTSQAHSLPLSPASTRQQIDE - 18220336
HTP
 - MOD_GSK3_1
 - -
0.62
 --
S 907 TTSQAHSLPLSPASTRQQIDE - 18669648
HTP
 - MOD_GSK3_1
 - -
0.62
 --
S 923 QQIDELRDSDSVCDSGVETSF IKK_group 11158290
LTP
0.09
 - -
0.49
 --
S 923 QQIDELRDSDSVCDSGVETSF IKK_alpha 11158290
LTP
0.09
 - -
0.49
 --
S 923 QQIDELRDSDSVCDSGVETSF IKK_beta 10469655
LTP
0.09
 - -
0.49
 --
S 923 QQIDELRDSDSVCDSGVETSF IKK_alpha 10469655
LTP
0.09
 - -
0.49
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_group 11158290
LTP
1.00
 - -
0.41
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_alpha 11158290
LTP
1.00
 - -
0.41
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_group 12482991
LTP
1.00
 - -
0.41
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_alpha 12482991
LTP
1.00
 - -
0.41
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_beta 10469655
LTP
1.00
 - -
0.41
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_alpha 10469655
LTP
1.00
 - -
0.41
 --
T 939 VETSFRKLSFTESLTSGASLL - 18669648
HTP
0.06
 - -
0.34
 --
S 941 TSFRKLSFTESLTSGASLLTL - 18669648
HTP
0.19
 - -
0.32
 --

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