Substrate: PKC alpha (Serine/threonine kinase)
Seq-ID: P20444 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-4545254   CLOCK_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
calcium-dependent protein kinase C activity,
ATP binding,
zinc ion binding,
protein binding		 plasma membrane,
mitochondrion,
nucleus		 positive regulation of protein amino acid phosphorylation,
inactivation of MAPK activity,
negative regulation of insulin receptor signaling pathway,
negative regulation of cell proliferation,
negative regulation of glucose import,
cellular calcium ion homeostasis,
neutrophil chemotaxis,
positive regulation of inflammatory response,
regulation of muscle contraction,
induction of apoptosis by intracellular signals,
induction of positive chemotaxis,
regulation of the force of heart contraction,
regulation of peptidyl-tyrosine phosphorylation,
chondrocyte differentiation,
negative regulation of protein amino acid phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 319 KLGPVGNKVISPSEDRKQPSN - 17114649
HTP
0.16
 - -
0.65
 - medium
T 497 EHMMDGVTTRTFCGTPDYIAP PKC_beta 15364915
LTP
1.00
 - S_TKc
0.20
 - medium
S 657 NIDQSDFEGFSYVNPQFVHPI - 12881490
LTP
0.88
 - S_TK_X
0.23
 - medium
S 657 NIDQSDFEGFSYVNPQFVHPI - 17141160
LTP
0.88
 - S_TK_X
0.23
 - medium
Y 658 IDQSDFEGFSYVNPQFVHPIL SYK 12881490
LTP
0.55
 - S_TK_X
0.24
 - medium

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