Substrate: CD95 antigen (Cell surface receptor)
Seq-ID: P25445 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-18737   FADD_HUMAN
MINT-4055317   CASP8_HUMAN
MINT-4085360   FYN_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
transmembrane receptor activity,
kinase binding		 extracellular region,
death-inducing signaling complex,
cytosol,
integral to membrane,
soluble fraction		 positive regulation of necrotic cell death,
induction of apoptosis by extracellular signals,
protein complex assembly,
anti-apoptosis,
immune response,
activation of pro-apoptotic gene products
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 91 DCVPCQEGKEYTDKAHFSSKC - 17195092
LTP
1.00
 - TNFR
0.11
 --
Y 91 DCVPCQEGKEYTDKAHFSSKC - 15660394
LTP
1.00
 - TNFR
0.11
 --
S 209 CRKHRKENQGSHESPTLNPET - 18669648
HTP
0.82
 - -
0.63
 --
S 212 HRKENQGSHESPTLNPETVAI - 18669648
HTP
1.00
 - -
0.60
 --
T 214 KENQGSHESPTLNPETVAINL - 18669648
HTP
0.07
 - -
0.56
 --
T 219 SHESPTLNPETVAINLSDVDL - 18669648
HTP
0.17
 - DEATH
0.41
 --
Y 232 INLSDVDLSKYITTIAGVMTL - 17195092
LTP
1.00
 - DEATH
0.16
 3EZQ 40.61%
Y 232 INLSDVDLSKYITTIAGVMTL - 15660394
LTP
1.00
 - DEATH
0.16
 3EZQ 40.61%
Y 291 WHQLHGKKEAYDTLIKDLKKA - 17195092
LTP
0.97
 Fyn SH2;
INPP5D SH2		 DEATH
0.33
 3EZQ 62.45%
Y 291 WHQLHGKKEAYDTLIKDLKKA - 15660394
LTP
0.97
 Fyn SH2;
INPP5D SH2		 DEATH
0.33
 3EZQ 62.45%

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