Substrate: Proteasome subunit alpha type 2 (Peptidase T1A family)
Seq-ID: P25787 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-51360   PSA4_HUMAN
MINT-3373107   PSMD4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
threonine-type endopeptidase activity,
protein binding		 cytoplasm,
proteasome core complex, alpha-subunit complex,
nucleus		 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,
response to virus
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 24 SPSGKLVQIEYALAAVAGGAP - 15592455
HTP
0.94
 - Proteasome_A_N
0.12
 1IRU 67.25%
Y 57 ATEKKQKSILYDERSVHKVEP - 18083107
HTP
0.42
 - Proteasome
0.32
 1IRU 63.32%
Y 76 EPITKHIGLVYSGMGPDYRVL - 18083107
HTP
0.98
 - Proteasome
0.13
 1IRU 13.54%
Y 98 HRARKLAQQYYLVYQEPIPTA - 15592455
HTP
0.60
 - Proteasome
0.12
 1IRU 36.68%

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