Substrate: PI3-kinase p85-alpha subunit (Adaptor molecule. Phopshatidylinositol 3-kinase regulatory alpha subunit.)
Seq-ID: P26450 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19635   CTNB1_MOUSE
MINT-19729   PK3CB_HUMAN
MINT-19828   SH3G1_MOUSE
MINT-59445   EPOR_MOUSE
MINT-6381887   IRS1_MOUSE
MINT-7214388   LYN_MOUSE
MINT-7214429   BLK_MOUSE
MINT-7214442   FYN_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ErbB-3 class receptor binding,
1-phosphatidylinositol-3-kinase activity,
insulin-like growth factor receptor binding,
phosphoinositide 3-kinase regulator activity,
insulin receptor binding,
insulin receptor substrate binding		 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex B cell differentiation,
protein amino acid phosphorylation,
negative regulation of apoptosis,
positive regulation of cell migration,
signal transduction,
insulin-like growth factor receptor signaling pathway,
negative regulation of cell-matrix adhesion,
negative regulation of osteoclast differentiation,
insulin receptor signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 508 CQTQERYSKEYIGKFKREGNE PDGFR_beta 8086421
LTP
1.00
 - -
0.48
 2RD0 86.90%
Y 607 WLGNENTEDQYSLVEDDEDLP - 15592455
HTP
1.00
 - -
0.55
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