Substrate: Tyrosine-protein phosphatase, non-receptor type 6 (Protein tyrosine phosphatase containing SH2 domains)
Seq-ID: P29351 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-74896   EPOR_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
protein tyrosine phosphatase activity,
phosphotyrosine binding,
SH2 domain binding		 cytoplasm,
nucleus,
alpha-beta T cell receptor complex		 intracellular signaling pathway,
B cell receptor signaling pathway,
negative regulation of T cell proliferation,
negative regulation of MAP kinase activity,
cytokine-mediated signaling pathway,
natural killer cell mediated cytotoxicity,
negative regulation of T cell receptor signaling pathway,
negative regulation of peptidyl-tyrosine phosphorylation,
protein amino acid dephosphorylation,
negative regulation of humoral immune response mediated by circulating immunoglobulin,
negative regulation of MAPKKK cascade,
regulation of B cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 536 IQSQKGQESEYGNITYPPAVR - 8114715
LTP
1.00
 - -
0.52
 - medium
Y 564 RTSSKHKEEVYENVHSKSKKE - 8114715
LTP
1.00
 - -
0.68
 - medium

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