Substrate: cdc25A (Dual specificity phosphatase)
Seq-ID: P30304 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-15591   CHK2_HUMAN
MINT-3294407   1433Z_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein tyrosine phosphatase activity,
protein binding		 nucleoplasm regulation of cyclin-dependent protein kinase activity,
cell division,
protein amino acid dephosphorylation,
mitosis,
DNA replication,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 18 PHRRRLLFACSPPPASQPVVK CDK1 12411508
LTP
0.22
 - -
0.54
 - high
S 76 KNNSNLQRMGSSESTDSGFCL - 12110582
LTP
1.00
 - -
0.62
 - high
S 76 KNNSNLQRMGSSESTDSGFCL CHK1 14681206
LTP
1.00
 - -
0.62
 - high
S 76 KNNSNLQRMGSSESTDSGFCL CHK1 12759351
LTP
1.00
 - -
0.62
 - high
S 79 SNLQRMGSSESTDSGFCLDSP - 14681206
LTP
1.00
 - -
0.63
 - high
S 82 QRMGSSESTDSGFCLDSPGPL - 14681206
LTP
0.23
 - -
0.66
 - high
S 88 ESTDSGFCLDSPGPLDSKENL - 14603323
LTP
1.00
 - M-inducer_phosp
0.67
 - high
S 116 HSLPQKLLGCSPALKRSHSDS CDK1 12411508
LTP
1.00
 - M-inducer_phosp
0.51
 - high
S 116 HSLPQKLLGCSPALKRSHSDS PIM-1 12411508
LTP
1.00
 - M-inducer_phosp
0.51
 - high
S 124 GCSPALKRSHSDSLDHDIFQL CHK1 12399544
LTP
0.29
 - M-inducer_phosp
0.45
 - high
S 124 GCSPALKRSHSDSLDHDIFQL CHK1 12676583
LTP
0.29
 - M-inducer_phosp
0.45
 - high
S 124 GCSPALKRSHSDSLDHDIFQL CHK1 12759351
LTP
0.29
 - M-inducer_phosp
0.45
 - high
S 124 GCSPALKRSHSDSLDHDIFQL CHK2 11298456
LTP
0.29
 - M-inducer_phosp
0.45
 - high
S 178 GKDLFTQRQNSAPARMLSSNE CHK2 12676583
LTP
1.00
 - M-inducer_phosp
0.69
 - high
S 178 GKDLFTQRQNSAPARMLSSNE CHK1 12676583
LTP
1.00
 - M-inducer_phosp
0.69
 - high
S 279 TRSVLKRPERSQEESPPGSTK CHK2 12676583
LTP
0.07
 - M-inducer_phosp
0.89
 - high
S 279 TRSVLKRPERSQEESPPGSTK CHK1 12676583
LTP
0.07
 - M-inducer_phosp
0.89
 - high
S 293 SPPGSTKRRKSMSGASPKEST CHK2 12676583
LTP
1.00
 - M-inducer_phosp
0.89
 - high
S 293 SPPGSTKRRKSMSGASPKEST CHK1 12676583
LTP
1.00
 - M-inducer_phosp
0.89
 - high
T 507 DLKKFRTKSRTWAGEKSKREM CHK1 14559997
LTP
1.00
 - -
0.37
 - high

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