Substrate: VEGFR-2 (Receptor tyrosine kinase)
Seq-ID: P35968 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-49634   CADH5_HUMAN
MINT-49637   SHC1_HUMAN
MINT-2834292   NRP1_HUMAN
MINT-3381238   GRB2_HUMAN
MINT-3381278   NCK1_HUMAN
MINT-3381335   FYN_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Hsp90 protein binding,
vascular endothelial growth factor receptor activity,
receptor signaling protein tyrosine kinase activity,
ATP binding,
growth factor binding,
integrin binding		 integral to plasma membrane positive regulation of positive chemotaxis,
protein amino acid phosphorylation,
positive regulation of endothelial cell proliferation,
angiogenesis,
regulation of cell shape,
interspecies interaction between organisms,
positive regulation of endothelial cell migration,
positive regulation of focal adhesion assembly
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 801 RANGGELKTGYLSIVMDPDEL - 11741094
LTP
1.00
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2		 -
0.23
 --
Y 951 KGARFRQGKDYVGAIPVDLKR KDR 10579917
LTP
0.03
 - TyrKc
0.21
 2OH4 25.23%
Y 951 KGARFRQGKDYVGAIPVDLKR - 11435426
LTP
0.03
 - TyrKc
0.21
 2OH4 25.23%
Y 996 VEEEEAPEDLYKDFLTLEHLI KDR 10579917
LTP
0.30
 - TyrKc
0.13
 2P2H 26.20%
Y 1054 ICDFGLARDIYKDPDYVRKGD KDR 10579917
LTP
1.00
 - TyrKc
0.13
 1YWN 75.55%
Y 1054 ICDFGLARDIYKDPDYVRKGD - 18083107
HTP
1.00
 - TyrKc
0.13
 1YWN 75.55%
Y 1059 LARDIYKDPDYVRKGDARLPL - 10579917
LTP
1.00
 - TyrKc
0.18
 1YWN 103.49%
Y 1059 LARDIYKDPDYVRKGDARLPL - 11435426
LTP
1.00
 - TyrKc
0.18
 1YWN 103.49%
Y 1059 LARDIYKDPDYVRKGDARLPL - 18083107
HTP
1.00
 - TyrKc
0.18
 1YWN 103.49%
Y 1175 QANAQQDGKDYIVLPISETLS KDR 10579917
LTP
1.00
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2		 -
0.41
 --
Y 1175 QANAQQDGKDYIVLPISETLS KDR 11387210
LTP
1.00
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2		 -
0.41
 --
Y 1175 QANAQQDGKDYIVLPISETLS - 10749680
LTP
1.00
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2		 -
0.41
 --
Y 1175 QANAQQDGKDYIVLPISETLS - 14532277
LTP
1.00
 PLCG1 SH2;
PLCG2 SH2;
PLCG_group SH2;
SHB SH2;
SHC2 SH2		 -
0.41
 --
Y 1214 EEEVCDPKFHYDNTAGISQYL KDR 12023952
LTP
0.24
 Src SH2 -
0.46
 --
Y 1214 EEEVCDPKFHYDNTAGISQYL KDR 11387210
LTP
0.24
 Src SH2 -
0.46
 --

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