Substrate: PPARG (Transcription factor)
Seq-ID: P37231 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
specific transcriptional repressor activity,
transcription activator binding,
transcription activator activity,
arachidonic acid binding,
zinc ion binding,
promoter binding,
sequence-specific DNA binding transcription factor activity,
drug binding,
retinoid X receptor binding,
prostaglandin receptor activity,
steroid hormone receptor activity		 cytosol,
nucleus		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
regulation of blood pressure,
epithelial cell differentiation,
white fat cell differentiation,
lipoprotein transport,
negative regulation of receptor biosynthetic process,
negative regulation of sequestering of triglyceride,
positive regulation of transcription factor activity,
activation of caspase activity,
placenta development,
cell fate commitment,
cell maturation,
innate immune response,
lipid homeostasis,
negative regulation of macrophage derived foam cell differentiation,
low-density lipoprotein receptor biosynthetic process,
monocyte differentiation,
regulation of cholesterol transporter activity,
response to lipid,
long-chain fatty acid transport,
positive regulation of fat cell differentiation,
response to low-density lipoprotein stimulus,
cellular response to insulin stimulus,
negative regulation of cholesterol storage,
induction of apoptosis,
transcription,
glucose homeostasis
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 112 YQSAIKVEPASPPYYSEKTQL MAPK1 9030579
LTP
1.00
 MOD_ProDKin_1
 - -
0.37
 - medium
S 112 YQSAIKVEPASPPYYSEKTQL MAPK8 9030579
LTP
1.00
 MOD_ProDKin_1
 - -
0.37
 - medium

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