Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

STAT 3 (Transcription factor)

Seq-ID:

P40763 [Homo sapiens]

Download:

Interaction Network(s):

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-74756 ERBB2_HUMAN
MINT-6764613 PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein dimerization activity, calcium ion binding, hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity, protein kinase binding, transcription activator activity, transcription factor binding, sequence-specific DNA binding transcription factor activity	plasma membrane, cytoplasm, nucleus	interleukin-6-mediated signaling pathway, eating behavior, glucose homeostasis, cellular component movement, response to estradiol stimulus, temperature homeostasis, interspecies interaction between organisms, JAK-STAT cascade involved in growth hormone signaling pathway, sexual reproduction, eye photoreceptor cell differentiation, negative regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	691	EAFGKYCRPESQEHPEADPGS	-	17525332	HTP	0.18		-	-	0.67	-	-
Y	705	PEADPGSAAPYLKTKFICVTP	-	9083098	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	11429593	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	JAK2	9582023	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	15592455	HTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	12244095	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	14551213	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	ALK	11850821	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	9305919	LTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
Y	705	PEADPGSAAPYLKTKFICVTP	-	18083107	HTP	0.63		STAT3 SH2	-	0.34	1BG1	138.86%
T	714	PYLKTKFICVTPTTCSNTIDL	-	18669648	HTP	0.16		-	-	0.21	1BG1	20.55%
T	717	KTKFICVTPTTCSNTIDLPMS	-	18669648	HTP	0.44		-	-	0.27	-	-
S	727	TCSNTIDLPMSPRTLDSLMQF	-	14551213	LTP	0.75		-	-	0.45	-	-
S	727	TCSNTIDLPMSPRTLDSLMQF	IRAK1	15465816	LTP	0.75		-	-	0.45	-	-
S	727	TCSNTIDLPMSPRTLDSLMQF	PKC_delta	16951338	LTP	0.75		-	-	0.45	-	-
S	727	TCSNTIDLPMSPRTLDSLMQF	-	18669648	HTP	0.75		-	-	0.45	-	-