Substrate: USP8 (Enzyme: ubiquitin hydrolase)
Seq-ID: P40818 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50371   1433T_HUMAN
MINT-50951   1433B_HUMAN
MINT-3318133   1433Z_HUMAN
MINT-3975807   1433S_HUMAN
MINT-6946830   CHM2A_HUMAN
MINT-6946846   CHM2B_HUMAN
MINT-6946902   CHMP5_HUMAN
MINT-7034470   NBR1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
ubiquitin thiolesterase activity,
ubiquitin-specific protease activity,
cysteine-type endopeptidase activity		 early endosome,
cytosol,
endosome membrane,
nucleus,
extrinsic to plasma membrane		 cell cycle,
endosome organization,
protein K48-linked deubiquitination,
ubiquitin-dependent protein catabolic process,
cell proliferation,
protein K63-linked deubiquitination
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 378 QNERMGPLNISTPVEPVAASK - 18669648
HTP
0.21
 - -
0.69
 - medium
S 389 TPVEPVAASKSDVSPIIQPVP - 18669648
HTP
0.38
 - -
0.60
 - medium
S 392 EPVAASKSDVSPIIQPVPSIK - 18669648
HTP
0.95
 - -
0.58
 - medium
S 452 PDRSTKPVVFSPTLMLTDEEK - 18669648
HTP
0.56
 - -
0.72
 - medium
Y 717 DREPSKLKRSYSSPDITQAIQ - 18669648
HTP
1.00
 - -
0.72
 - medium
S 718 REPSKLKRSYSSPDITQAIQE - 18220336
HTP
1.00
 - -
0.71
 - medium
S 718 REPSKLKRSYSSPDITQAIQE - 18669648
HTP
1.00
 - -
0.71
 - medium
S 719 EPSKLKRSYSSPDITQAIQEE - 18669648
HTP
1.00
 - -
0.71
 - medium

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