Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

STAT 5 (Transcription factor)

Seq-ID:

P42229 [Homo sapiens]

Download:

Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-50646   ESR1_HUMAN
MINT-58264   STAP2_HUMAN
MINT-6793989   PTN1_HUMAN
MINT-7891339   EPOR_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, sequence-specific DNA binding transcription factor activity, protein binding	cytoplasm, nucleus	valine metabolic process, oxaloacetate metabolic process, transcription, creatinine metabolic process, isoleucine metabolic process, JAK-STAT cascade, taurine metabolic process, allantoin metabolic process, fatty acid metabolic process, citrate metabolic process, 2-oxoglutarate metabolic process, succinate metabolic process, creatine metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	90	GFLLKIKLGHYATQLQKTYDR	-	16497976	HTP	0.04		-	STAT_int	0.12	-	medium
S	193	QAQFAQLAQLSPQERLSRETA	-	18669648	HTP	0.74		-	STAT_alpha	0.30	-	medium
Y	694	TPVLAKAVDGYVKPQIKQVVP	Lyn	11641791	LTP	0.25		CRKL SH2; PTPN11 SH2; STAT5 SH2	SH2	0.20	-	medium
Y	694	TPVLAKAVDGYVKPQIKQVVP	SRC	11641791	LTP	0.25		CRKL SH2; PTPN11 SH2; STAT5 SH2	SH2	0.20	-	medium
Y	694	TPVLAKAVDGYVKPQIKQVVP	JAK2	11641791	LTP	0.25		CRKL SH2; PTPN11 SH2; STAT5 SH2	SH2	0.20	-	medium
Y	694	TPVLAKAVDGYVKPQIKQVVP	-	17081983	HTP	0.25		CRKL SH2; PTPN11 SH2; STAT5 SH2	SH2	0.20	-	medium
Y	694	TPVLAKAVDGYVKPQIKQVVP	-	18083107	HTP	0.25		CRKL SH2; PTPN11 SH2; STAT5 SH2	SH2	0.20	-	medium
S	780	RPMDSLDSRLSPPAGLFTSAR	MAPK1	10194762	LTP	0.43	MOD_ProDKin_1	-	-	0.55	-	medium
S	780	RPMDSLDSRLSPPAGLFTSAR	MAPK3	10194762	LTP	0.43	MOD_ProDKin_1	-	-	0.55	-	medium