Substrate: CDKN2A (cyclin-dependent protein kinase inhibitor a..., protein binding)
Seq-ID: P42771 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-25084   CDK6_HUMAN
MINT-50391   CC45L_HUMAN
MINT-50406   CDC6_HUMAN
MINT-50444   GEMI_HUMAN
MINT-58445   B3AT_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cyclin-dependent protein kinase inhibitor activity,
protein kinase binding,
NF-kappaB binding,
protein binding		 cytoplasm,
nucleus		 negative regulation of cyclin-dependent protein kinase activity,
senescence,
negative regulation of NF-kappaB transcription factor activity,
negative regulation of cell proliferation,
negative regulation of cell growth,
cell cycle arrest,
G1/S transition of mitotic cell cycle,
negative regulation of cell-matrix adhesion,
positive regulation of smooth muscle cell apoptosis,
Ras protein signal transduction,
induction of apoptosis,
cell cycle checkpoint,
positive regulation of myeloid cell apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 7     MEPAAGSSMEPSADWLA - 12529334
LTP
0.59
 - -
0.54
 --
S 8    MEPAAGSSMEPSADWLAT - 12529334
LTP
0.59
 - -
0.52
 --
S 140 LRAAAGGTRGSNHARIDAAEG - 12529334
LTP
0.51
 - -
0.56
 --
S 152 HARIDAAEGPSDIPD       - 12529334
LTP
0.32
 - -
0.66
 --

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