Substrate: ECE1 (metalloendopeptidase activity)
Seq-ID: P42892 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
metal ion binding,
peptide hormone binding,
metalloendopeptidase activity		 plasma membrane,
Weibel-Palade body,
membrane fraction,
external side of plasma membrane,
early endosome,
integral to membrane,
intrinsic to endosome membrane,
perinuclear region of cytoplasm		 calcitonin catabolic process,
bradykinin catabolic process,
regulation of systemic arterial blood pressure by endothelin,
regulation of vasoconstriction,
endothelin maturation,
heart development,
substance P catabolic process,
positive regulation of receptor recycling,
embryonic digit morphogenesis,
ear development
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 34 ATLDEEDLVDSLSEGDAYPNG - 17081983
HTP
0.15
 - -
0.38
 - medium
S 34 ATLDEEDLVDSLSEGDAYPNG - 18669648
HTP
0.15
 - -
0.38
 - medium
S 36 LDEEDLVDSLSEGDAYPNGLQ - 18669648
HTP
0.53
 - -
0.36
 - medium
S 51 YPNGLQVNFHSPRSGQRCWAA - 18669648
HTP
0.00
 - -
0.26
 - medium

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