Substrate: Beta-arrestin 1 (Adapter molecule)
Seq-ID: P49407 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19558   RTN3_MOUSE
MINT-19561   SON_MOUSE
MINT-19655   TOP2A_MOUSE
MINT-19697   NF2L2_MOUSE
MINT-19723   VIME_MOUSE
MINT-19787   ROA1_MOUSE
MINT-19799   MDM2_MOUSE
MINT-4791905   AGTR1_HUMAN
MINT-7263136   MK10_HUMAN
MINT-7263254   M3K5_HUMAN
MINT-7263269   MP2K4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin-like growth factor receptor binding,
ubiquitin protein ligase binding,
enzyme inhibitor activity,
GTPase activator activity,
angiotensin receptor binding,
transcription factor binding,
promoter binding		 plasma membrane,
membrane fraction,
pseudopodium,
chromatin,
cytoplasmic membrane-bounded vesicle,
coated pit,
soluble fraction,
nucleus		 positive regulation of ERK1 and ERK2 cascade,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of interleukin-8 production,
negative regulation of NF-kappaB transcription factor activity,
histone H4 acetylation,
negative regulation of protein ubiquitination,
negative regulation of signal transduction,
proteasomal ubiquitin-dependent protein catabolic process,
protein ubiquitination,
protein transport,
post-Golgi vesicle-mediated transport,
sensory perception,
positive regulation of histone acetylation,
G-protein coupled receptor internalization,
positive regulation of Rho protein signal transduction,
stress fiber assembly,
negative regulation of interleukin-6 production,
transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 54 DPEYLKERRVYVTLTCAFRYG SRC 17456469
LTP
0.87
 - Arrestin_N
0.10
 1G4M 3.06%
S 412 DKEEEEDGTGSPQLNNR     - 10347142
LTP
0.66
 - -
0.93
 --
S 412 DKEEEEDGTGSPQLNNR     - 9388255
LTP
0.66
 - -
0.93
 --

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