Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

GSK-3 alpha (Glycogen synthase kinase-3 alpha)

Seq-ID:

P49840 [Homo sapiens]

Download:

Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

MINT-4544606 AXN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, tau-protein kinase activity, ATP binding, protein kinase A catalytic subunit binding	beta-catenin destruction complex, cytosol	positive regulation of protein catabolic process, protein amino acid phosphorylation, negative regulation of insulin receptor signaling pathway, negative regulation of transferase activity, negative regulation of glucose import, insulin receptor signaling pathway, negative regulation of UDP-glucose catabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	19	GGPGGSGRARTSSFAEPGGGG	-	18669648	HTP	0.72		-	-	0.92	-	medium
S	20	GPGGSGRARTSSFAEPGGGGG	-	18669648	HTP	0.24		-	-	0.92	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKA_group	11035810	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKC_group	11884598	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	-	11749387	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKB_group	11577096	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	-	17192257	HTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKB_group	11563975	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
S	21	PGGSGRARTSSFAEPGGGGGG	PKB_group	11340086	LTP	0.71	MOD_PKB_1	-	-	0.91	-	medium
Y	279	QLVRGEPNVSYICSRYYRAPE	-	15592455	HTP	1.00		-	S_TKc	0.08	-	medium
Y	279	QLVRGEPNVSYICSRYYRAPE	-	17192257	HTP	1.00		-	S_TKc	0.08	-	medium
Y	279	QLVRGEPNVSYICSRYYRAPE	-	18088087	HTP	1.00		-	S_TKc	0.08	-	medium
Y	279	QLVRGEPNVSYICSRYYRAPE	-	18083107	HTP	1.00		-	S_TKc	0.08	-	medium
Y	279	QLVRGEPNVSYICSRYYRAPE	-	18669648	HTP	1.00		-	S_TKc	0.08	-	medium